ChromoTek is a biotech company offering a new class of immunologic research tools derived from single domain camel antibodies for cell biology and proteomics.
Chromotek – single domain camel antibodies
ChromoTek’s products are based on its proprietary Chromobody technology. These innovative single domain camel antibody fragments are either coupled to a fluorescent dye (Booster), to a matrix (Nano-Traps), or fused to a fluorescent protein (Chromobodies) or are part of an assay system to study protein-protein interactions (F2H-Assay). Their extremely small size and high stability make them ideal reagents for biomolecular research and live cell assays. ChromoTek’s Nano-Traps (RFP-Trap, GFP-Trap, etc…) are routinely used in thousands of labs to pulldown tagged proteins and interaction partners. Indeed, these recombinant binding proteins allow fast, efficient and reliable analytical and preparative one-step purification of proteins for a multitude of downstream applications (Western Blot, Mass spec, ChIP, etc…). Furthermore, Booster are useful to increase the fluorescence signal in various microscopy applications by attaching a stable chemical fluorescent dye to green fluorescent or red fluorescent protein tags. Additionally, Chromobodies are functional in living cells where they detect and visualize endogenous target structures in real time. Moreover, the F2H-Assay allows to directly visualize protein-protein interactions in live cells. By tethering a fluorescent bait at a defined cellular structure, ChromoTek generates a positional protein-protein interaction biosensor and assay for co-localization of fluorescent prey proteins in living cells. Automated image acquisition and analyses allow researchers to perform high throughput screens for molecules and drugs perturbing specific protein-protein interactions in the cellular environment and in real time.
Founded in 2007 as a spin-off from the Ludwig-Maximilians University Munich (LMU) by a research team around Ulrich Rothbauer, ChromoTek has rapidly developed to become a renowned supplier of innovative reagents as well as a trusted service provider for big pharma. Its management team combines complementary skills and experiences that form a basis for sustained growth (Marion Jung, Katrin Schmidthals and Octavian Schatz). ChromoTek GmbH is based in Germany and USA.
More about Chromotek : www.chromotek.com