#news #biotech How large-scale single cell genomics complements metagenomics studies

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How large-scale single cell genomics complements metagenomics studies .Researchers demonstrated the value of conducting large-scale single cell genomics by collecting nearly 500 single cells from a single low diversity hot spring sediment sample. Their work showed that single cell genomics can add significant value to the other commonly used culture-independent sequencing approaches including amplicon and metagenomic sequencing. For example, they showed that the composition of the community was similar across sequencing approaches, that species specific sets of single cells harbored mobile genetic elements that were missed within paired metagenome assembled genomes (MAGs), and that dominant populations varied with respect to the amount of within species recombination, indicating variation in gene flow between the analyzed community members.

from Biotechnology News – Biology News https://ift.tt/Nq42KJM