O3 Holding GmbH – Publication Q4 2025 Interim Report

BIOGGIO, SWITZERLAND, 28 February 2026 – O3 Holding GmbH (the Company), the holding company of KD Pharma Group, a leading CDMO in pharmaceutical and nutritional lipids, announces that the publication of its Q4 2025 Interim Report, due  under the bond terms for The Company’s FRN Senior Secured EUR 180,000,000 bond issue with ISIN NO0013360552 issued on 28 October 2024, has now been published on the Company’s website (www.kdpharmagroup.com/investor-relations).

For further information please contact:

investor.relations@kdpharmagroup.com

Immunic, Inc. Reports Year-End 2025 Financial Results and Provides Corporate Update

– Top-Line Data from Phase 3 ENSURE Trials of Vidofludimus Calcium in Relapsing Multiple Sclerosis Expected by Year-End 2026 – 

– Raised Proceeds of $200 Million in a Private Placement, with Potential for up to an Additional $200 Million – 

– Net Proceeds Expected to Fund Completion of Phase 3 ENSURE Trials in Relapsing Multiple Sclerosis, Initiation of Phase 3 Trial in Primary Progressive Multiple Sclerosis and Begin of Transition into a Commercial Organization – 

NEW YORK, February 26, 2026 – Immunic, Inc. (Nasdaq: IMUX), a late-stage biotechnology company pioneering the development of novel oral therapies for neurologic and gastrointestinal diseases, today announced financial results for the year ended December 31, 2025, and provided a corporate update.

“The phase 3 ENSURE-1 and ENSURE-2 trials of our lead asset, orally available nuclear receptor-related 1 (Nurr1) activator, vidofludimus calcium (IMU-838) in relapsing multiple sclerosis (RMS) continue to progress, with top-line data expected to be available by the end of 2026,” stated Daniel Vitt, Ph.D., Chief Executive Officer of Immunic. “As we continue to advance our multiple sclerosis (MS) program with vidofludimus calcium, we were extremely pleased to have recently announced the successful completion of an oversubscribed private placement of up to $400 million in gross proceeds, with $200 million in upfront gross proceeds. This financing is truly a pivotal milestone for Immunic and positions us to confidently transition into a fully integrated commercial-stage company. The transaction was led by our existing investor BVF Partners L.P. with participation from a group of highly regarded new and other existing investors. This level of commitment reflects growing confidence in our program and reinforces our belief in vidofludimus calcium’s potential to address the underlying drivers of MS progression.”

“The proceeds from the initial closing are expected to fund our operations through the ENSURE top-line data and our planned RMS New Drug Application (NDA) submission in the United States in mid-2027, with a targeted potential regulatory approval date in 2028,” continued Dr. Vitt. “They also support preparations for the potential launch of vidofludimus calcium in RMS, including expansion of our medical and commercial infrastructure. Additionally, based on the totality of the phase 2 CALLIPER trial data in progressive MS, which showed not only substantial and medically relevant reductions for vidofludimus calcium in delaying 24-week confirmed disability progression but also statistically significant 24-week confirmed disability improvement, while confirming the drug’s favorable safety and tolerability profile already observed in previous clinical trials, we plan to initiate a confirmatory phase 3 program in primary progressive multiple sclerosis (PPMS) later this year as well.”

Jason Tardio, President and Chief Operating Officer of Immunic, added, “This is an exciting moment for Immunic and for individuals living with MS, as we believe that vidofludimus calcium could represent a potentially transformative approach to disease modification. Current oral therapies for RMS mainly control inflammation and relapses, often have complex safety and tolerability issues and do not adequately address the neurodegenerative processes driving disability progression and long-term disability. In contrast, vidofludimus calcium is uniquely designed to provide direct neuroprotective effects by enhancing neuronal survival and function through Nurr1 activation, while reducing new inflammatory damage via selective DHODH inhibition. This first-in-class mechanism has the potential to address the two key biological drivers of disability progression—relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA)—potentially offering advantages over currently available therapies that primarily focus on inflammatory relapses. As such, we believe vidofludimus calcium may achieve a best-in-class benefit-risk profile and, therefore, could represent a large commercial opportunity in the global MS market, which is projected to reach over $30 billion by the early 2030s.” 

Fourth Quarter 2025 and Subsequent Highlights 

• February 2026: Completed an oversubscribed private placement of up to $400 million in gross proceeds, led by existing investor BVF Partners L.P. with participation from Aberdeen Investments, Avidity Partners, Coastlands Capital, EcoR1 Capital, Janus Henderson Investors, OrbiMed, RA Capital Management, TCGX, Trails Edge Capital Partners, Vivo Capital, Woodline Partners LP, and other institutional investors. A total of $200 million in gross proceeds to Immunic was received upon closing on February 17, 2026.
  • Simona Skerjanec, former SVP, Global Head of Neuroscience and Rare Diseases at Roche, elevated to Interim Chairperson of the Board of Directors. Dr. Duane Nash, former Chairman, remains a member of the Board. Thor Nagel, Principal at BVF Partners L.P., appointed to the Board. Plans underway for further Board refreshment to support the company’s evolution into a commercial-stage organization.
  • Initiated search for a new Chief Executive Officer with deep commercial expertise in MS to lead Immunic into its next stage of growth and commercialization. Subsequently, Dr. Vitt will return to his roots and transition to a new senior executive role focused on scientific strategy and portfolio advancement, while remaining on the Board.
• February 2026: Presented additional data from the phase 2 CALLIPER trial of vidofludimus calcium in patients with progressive MS at the ACTRIMS Forum 2026. The findings, presented in two poster presentations, provide additional evidence of vidofludimus calcium’s effects on key biological drivers of disease progression, including antiviral immune responses linked to Epstein-Barr virus (EBV) and magnetic resonance imaging (MRI) markers of both acute-focal and chronic-compartmentalized inflammation. The findings further reinforce Immunic’s belief that vidofludimus calcium has the potential to address underlying mechanisms of disease progression in MS patients.

Anticipated Clinical Milestones

• Vidofludimus calcium in MS:

• Top-line data from the twin phase 3 ENSURE-1 and ENSURE-2 trials in RMS is expected by the end of 2026. Subsequently, Immunic plans to submit an NDA in the United States in mid-2027, with a targeted potential regulatory approval date in 2028.
• Initiation of a phase 3 clinical program in PPMS is expected later this year and estimated to take approximately 3.5 to 4 years to complete.

• IMU-856: The company continues preparing for further clinical testing of IMU-856, contingent on financing, licensing or partnering.

Financial and Operating Results 

• Research and Development (R&D) Expenses were $82.0 million for the twelve months ended December 31, 2025, as compared to $80.0 million for the twelve months ended December 31, 2024. The $1.9 million increase reflects (i) a $3.9 million increase in external development costs related to the vidofludimus calcium program and (ii) a $1.8 million increase in personnel expenses for R&D. The increase was offset by (i) a $3.0 million decrease in external development costs related to IMU-856 and (ii) a $0.8 million decrease across numerous categories.
• General and Administrative (G&A) Expenses were $21.2 million for the twelve months ended December 31, 2025, as compared to $18.0 million for the same period ended December 31, 2024. The $3.2 million increase was due to (i) a $1.9 million increase related to personnel expenses, of which $0.3 million was related to non-cash stock compensation, (ii) a $0.8 million increase in legal and consultancy expenses and (iii) a $0.5 million increase related to costs across numerous categories. 
• Interest Income was $1.0 million for the twelve months ended December 31, 2025, as compared to $3.4 million for the twelve months ended December 31, 2024. The $2.4 million decrease was due to a lower average cash balance.
• In the twelve months ended December 31, 2024, there was a non-cash charge related to the change in value of the tranche rights associated with the January 2024 Financing from January 8, 2024 until March 4, 2024. These tranches were initially classified as a liability, but were reclassified to equity on March 4, 2024, when stockholders approved the increase in the company’s authorized shares from 130 million to 500 million shares of common stock and, therefore, the tranche 2 and tranche 3 rights needed to be revalued to fair value upon the reclassification to equity. There was no change in fair value of the tranche rights recognized in the twelve months ended December 31, 2025.
• Other Income (Expense) was $5.0 million for the twelve months ended December 31, 2025, as compared to ($1.0 million) for the same period ended December 31, 2024. The $6.1 million increase was primarily attributable to (i) $4.8 million of grant income from the German Federal Ministry of Finance, of which $1.0 million was recognized in the first quarter 2025 and $3.8 million was recognized in the fourth quarter 2025, (ii) a $1.7 million expense related to the portion of deal costs from the January 2024 Financing related to the tranche rights that were established at the time of the deal closing in 2024 and (iii) a $0.3 million increase across numerous categories. The increase was offset by a $0.7 million decrease in research and development tax incentives for clinical trials in Australia due to lower clinical trial spend in Australia.
• Net Loss for the twelve months ended December 31, 2025, was approximately $97.2 million, or $0.62 per basic and diluted share, based on 155,688,030 weighted average common shares outstanding, compared to a net loss of approximately $100.5 million, or $1.00 per basic and diluted share, based on 100,174,766 weighted average common shares outstanding for the same period ended December 31, 2024.
• Cash and Cash Equivalents as of December 31, 2025 were approximately $15.5 million. With these funds and the approximately $187.0 million net cash proceeds raised in the February 2026 private placement, Immunic expects to be able to fund its operations into late 2027. 

About Immunic, Inc.

Immunic, Inc. (Nasdaq: IMUX) is a late-stage biotechnology company pioneering the development of novel oral therapies for neurologic and gastrointestinal diseases. The company’s lead development program, vidofludimus calcium (IMU-838), is currently in phase 3 clinical trials for the treatment of relapsing multiple sclerosis, for which top-line data is expected to be available by the end of 2026. It has already shown therapeutic activity in phase 2 clinical trials in relapsing-remitting multiple sclerosis, progressive multiple sclerosis and other diseases. Vidofludimus calcium combines neuroprotective effects, through its mechanism as a first-in-class nuclear receptor-related 1 (Nurr1) activator, with additional anti-inflammatory and anti-viral effects, by selectively inhibiting the enzyme dihydroorotate dehydrogenase (DHODH). IMU-856, which targets the protein Sirtuin 6 (SIRT6), is intended to restore intestinal barrier function and regenerate bowel epithelium, which could potentially be applicable in numerous gastrointestinal diseases such as celiac disease, inflammatory bowel disease, and Graft-versus-Host-Disease. IMU-381 comprises next-generation molecules in preclinical testing for neurologic, gastrointestinal and other autoimmune diseases leveraging the company’s Nurr1 platform. For further information, please visit: www.imux.com.

Cautionary Statement Regarding Forward-Looking Statements

This press release contains “forward-looking statements” that involve substantial risks and uncertainties for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, included in this press release regarding strategy, future operations, future financial position, future revenue, projected expenses, sufficiency of cash and cash runway, expected timing, development and results of clinical trials, prospects, plans and objectives of management are forward-looking statements. Examples of such statements include, but are not limited to, statements relating to Immunic’s development programs and the targeted diseases; the potential for Immunic’s development programs to safely and effectively target diseases; preclinical and clinical data for Immunic’s development programs; the feasibility of advancing vidofludimus calcium to a confirmatory phase 3 clinical trial in progressive multiple sclerosis; the timing of current and future clinical trials, anticipated clinical milestones and regulatory approvals; the nature, strategy and focus of the company and further updates with respect thereto; and the development and commercial potential of any product candidates of the company. Immunic may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in the forward-looking statements and you should not place undue reliance on these forward-looking statements. Such statements are based on management’s current expectations and involve substantial risks and uncertainties. Actual results and performance could differ materially from those projected in the forward-looking statements as a result of many factors, including, without limitation, increasing inflation, tariffs and macroeconomics trends, impacts of the Ukraine – Russia conflict and the conflict in the Middle East on planned and ongoing clinical trials, risks and uncertainties associated with the ability to project future cash utilization and reserves needed for contingent future liabilities and business operations, the availability of sufficient financial and other resources to meet business objectives and operational requirements, and the ability to raise sufficient capital to continue as a going concern, the fact that the results of earlier preclinical studies and clinical trials may not be predictive of future clinical trial results, any changes to the size of the target markets for the company’s products or product candidates, the protection and market exclusivity provided by Immunic’s intellectual property, risks related to the drug development and the regulatory approval process and the impact of competitive products and technological changes. A further list and descriptions of these risks, uncertainties and other factors can be found in the section captioned “Risk Factors,” in the company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2025, filed with the SEC on February 26, 2026, and in the company’s subsequent filings with the SEC. Copies of these filings are available online at www.sec.gov or ir.imux.com/sec-filings. Any forward-looking statement made in this release speaks only as of the date of this release. Immunic disclaims any intent or obligation to update these forward-looking statements to reflect events or circumstances that exist after the date on which they were made. Immunic expressly disclaims all liability in respect to actions taken or not taken based on any or all of the contents of this press release.

Contact Information

Immunic, Inc.
Jessica Breu
Vice President Investor Relations and Communications
+49 89 2080 477 09
jessica.breu@imux.com

US IR Contact
Rx Communications Group
Paula Schwartz
+1 917 633 7790
immunic@rxir.com

US Media Contact
KCSA Strategic Communications
Caitlin Kasunich
+1 212 896 1241
ckasunich@kcsa.com

Berlin, Germany, 26 February 2026. Eckert & Ziegler SE (ISIN DE0005659700, TecDAX) today announced that it has entered a partnership with Molecular Partners AG to enable the development and future manufacturing of Molecular Partners’ radiolabeled therapeutics (Radio-DARPins) based on its proprietary Designed Ankyrin Repeat Protein (DARPin) technology platform.

Under the agreement, Eckert & Ziegler will support Molecular Partners with a comprehensive range of services covering development activities for Radio-DARPins with Actinium-225 and Lutetium-177 payloads which show potential in the treatment of various cancers. The collaboration will leverage Eckert & Ziegler’s state-of-the-art laboratories, including the newly established development laboratory in Berlin. Thanks to its carefully selected and matched technical equipment, the facility offers ideal conditions for the advancement of radiopharmaceuticals based on alpha emitters.

DARPin molecules are a novel class of custom-built proteins. Their structure and favorable pharmacokinetic properties make them an attractive vector for the development of targeted radiopharmaceuticals, with the potential to address significant unmet medical needs.

“Supporting highly innovative companies such as Molecular Partners in developing their promising technology platforms is a key objective of our group,” said Dr. Harald Hasselmann, CEO of Eckert & Ziegler. “Bringing together our expertise in isotopes, radiochemistry and development infrastructure with our partners’ innovations will enable patients worldwide to benefit from new treatments in the future.”

The collaboration further strengthens Eckert & Ziegler’s position as a preferred partner for companies developing innovative radiopharmaceutical platforms and underscores its role in supporting the growing radiopharmaceutical ecosystem from early development through clinical supply to commercial phases.

About Eckert & Ziegler
Eckert & Ziegler SE, with more than 1,000 employees, is a leading specialist in isotope-related components for nuclear medicine and radiation therapy. The company offers a broad range of services and products for the radiopharmaceutical industry, from early development work to contract manufacturing and distribution. Eckert & Ziegler shares (ISIN DE0005659700) are listed in the TecDAX index of Deutsche Börse.
Contributing to saving lives.

About Molecular Partners AG
Molecular Partners AG (SIX: MOLN, NASDAQ: MOLN) is a clinical-stage biotech company pioneering a novel class of protein drugs known as DARPin therapeutics, for medical challenges other treatment modalities cannot readily address. Molecular Partners leverages the key properties of DARPins to design and develop differentiated therapeutics for cancer patients, including targeted radiopharmaceuticals and next-generation immune cell engagers. The Company has proprietary programs in various stages of pre-clinical and clinical development, as well as programs developed through partnerships with leading pharmaceutical companies and academic centers. Molecular Partners, founded in 2004, has offices in both Zurich, Switzerland and Concord, MA, USA. For more information, visit www.molecularpartners.com and find us on LinkedIn and Twitter / X @MolecularPrtnrs

Contact
Eckert & Ziegler SE
Robert-Rössle-Str. 10, 13125 Berlin, Germany
Jan Schöpflin, Marketing / Karolin Riehle, Investor Relations
jan.schoepflin@ezag.de / karolin.riehle@ezag.de
Tel.: +49 (0) 30 / 94 10 84-138; www.ezag.com

Molecular Partners
Seth Lewis, SVP Investor Relations & Strategy
Concord, Massachusetts, U.S.
seth.lewis@molecularpartners.com
Tel: +1 781 420 2361

Laura Jeanbart, PhD, Head of Portfolio Management & Communications
Zurich-Schlieren, Switzerland
laura.jeanbart@molecularpartners.com
Tel: +41 44 575 19 35

Gerresheimer AG: BaFin announces expansion of audit of 2024 consolidated financial statements and initiation of audit of 2025 Half-Year Financial Report

Düsseldorf, February 25, 2026. The German Federal Financial Supervisory Authority (BaFin) has informed Gerresheimer AG (ISIN: DE000A0LD6E6, “Gerresheimer”) that it intends to

• expand the audit of the published consolidated financial statements and the related Group management report for the 2023/2024 financial year of Gerresheimer AG, which was initiated on September 18, 2025, and

• initiate an audit of the published condensed interim consolidated financial statements and the related interim group management report for the period from December 1, 2024, to May 31, 2025, of Gerresheimer AG.

Expansion of the audit of the 2024 consolidated financial statements
According to BaFin, the reason for expanding the audit of the consolidated financial statements and the associated Group management report for the 2024 financial year from December 1, 2023, to November 30, 2024, is “concrete evidence that

1. the lease liabilities reported in the balance sheet with a carrying amount of €65.5 million and/or the undiscounted payment obligations corresponding to the lease liabilities disclosed in the notes may be incorrect;
    
2. the disclosure of the useful lives of development costs capitalized as intangible assets with a carrying amount of €29.4 million may be incorrect;
    
3. assets of the Advanced Technologies segment, which are reported in the balance sheet with a carrying amount of EUR 196.5 million, may have been impaired and that the impairment required in this case was not recognized.”

The assets of the Advanced Technologies segment relate to Sensile Medical AG, Olten, Switzerland. On February 10, 2026, Gerresheimer announced that non-cash impairments of approximately EUR 220 to 240 million were expected in the 2025 consolidated financial statements. These mainly relate to impairments of technology and development projects of Sensile Medical AG, Olten, Switzerland, and, among others, impairment losses to the assets of Gerresheimer Moulded Glass Chicago Inc., Chicago, USA.

Initiation of Audit of the 2025 Half-Year Financial Report
According to BaFin, the reason for the audit of the interim consolidated financial statements and the accompanying interim group management report for the period from December 1, 2024, to May 31, 2025 (Half-Year Financial Report) is “concrete indications that

1. the assessment of certain risks in the interim group management report for the period from December 1, 2024, to May 31, 2025, in conjunction with the 2023/24 Group management report, was no longer accurate due to the financing of the acquisition of Bormioli Pharma;

2. the recognition of impairment losses on assets was incorrectly omitted;
    
3. revenues and cost of sales in connection with bill and hold agreements were incorrectly recognized.”

In its 2025 Half-Year Financial Report, the Company classified the risks from acquisitions, divestments, and cooperations, as well as the liquidity risk, as low, unchanged from the 2024 consolidated financial statements. BaFin sees indications that maintaining the risk classification was no longer appropriate.
With regards to the recognition of revenues and costs in connection with bill and hold agreements, BaFin also intends to examine in the 2025 Half-Year Financial Report whether these revenues should have been recognized in the first half of 2025 or only at a later date. Linked to this is the accounting of inventories as of the balance sheet date of May 31, 2025.

On December 22, 2025, the Company had already announced that it would comprehensively correct revenues from bill and hold agreements, not include revenues from new bill and hold agreements in the 2025 consolidated financial statements, and refrain from this practice in the future. In addition, the Company had announced that it would also correct the recognition of revenues from bill and hold agreements in the following interim financial information for the 2026 financial year by adjusting the previous year’s figures.

Gerresheimer expects BaFin to initiate the announced expansion of its audit of the 2024 consolidated financial statements and the audit of the interim financial statements for the first half of 2025.

The Company will continue to cooperate fully with BaFin in the context of the audits in order to clarify the facts transparently.

______________________

End of insider information

Contact Gerresheimer AG

Investor Relations

Guido Pickert
Vice President Investor Relations

T: +49 211 6181 220
gerresheimer.ir@gerresheimer.com

PRESS RELEASE

BIO-Europe Spring® 2026 Charts the Future of Life Sciences from Lisbon’s Shores

MUNICH, GERMANY – February 25, 2026. The 20th annual BIO-Europe Spring is heading to Lisbon, Portugal, from March 23–25, 2026, with a digital experience to follow on March 31–April 1. For the first time, BIO-Europe Spring and LSX Europe will take place back-to-back as part of the Life Sciences Spring Innovation Week, creating a unique meeting point for the life science industry. With engagement already on the rise, Lisbon is poised to deliver expanded partnering, investment, and cross-border collaboration opportunities across the global life sciences ecosystem.

BIO-Europe Spring connects Europe’s top innovation centers with the global life sciences industry to cultivate thriving strategic partnerships. The 2026 edition in Lisbon will bring together over 3,700 international stakeholders – from academia, startups and scaling biotechs to top pharma executives and investors – for more than 20,000 high-impact partnering meetings.

Lisbon and Greater Lisbon, home to a rapidly growing life sciences cluster, feature internationally competitive pharmaceutical and biotech activity, world-class research institutions, major multinational hubs, and an emerging venture capital community – making the city an ideal host for this “must-attend” Life Sciences Spring Innovation Week.

For its 2026 edition, BIO-Europe Spring will feature an engaging program, curated by EBD Group (an Informa company), offering insightful content, high-impact partnering, and extensive networking opportunities.

BIO-Europe Spring 2026 Program Highlights Include:

• Opening plenary – Where the Compass Points: Redrawing the Map of Biotech Partnering
  Dive into a dynamic discussion about biotech partnering strategies by experienced executives from BioNTech, CellmAbs, Novo Holdings, and Ottimo Bio.
• The Art of Wayfinding with AI in Drug Discovery and Development
  Explore how AI is enhancing drug discovery and development and the complexities of integrating AI into the future of therapeutic innovations.
• Forecasting the Waves: Biopharma Investment Landscape
  Join globally recognized venture capital and strategic investors from LifeArc, Syncona, Biovance Capital, Sofinnova Partners, and Forbion to gain insights into navigating today’s biopharma funding landscape.
• High tide: China’s Innovation and Global Partnerships
  Understand the growing momentum of cross-border partnerships and the significant opportunities China brings to global biopharma companies to drive innovation.

Partnering and Registration

Partnering for BIO-Europe Spring is now open and in full swing. One-to-one meetings will be powered by partneringONE®, an industry-standard platform that enables delegates to search, request, schedule, and conduct meetings efficiently.

BIO-Europe Spring continues to provide a global platform for the biopharma community to connect. To enhance access and extend engagement beyond the in-person event, the conference will continue with two days of virtual partnering on March 31–April 1, allowing participants to connect regardless of time zone or travel constraints.

Registration information for BIO-Europe Spring is available online. Discounted rates are still available until March 20, 2026, with the next early bird deadline approaching on March 6, 2026.

Additional Links and Information

BIO-Europe Spring is organized by EBD Group, an Informa company.

For more information and live updates, please visit the conference website at: https://informaconnect.com/bioeurope-spring and follow BIO-Europe Spring 2026 on LinkedIn.

About Informa and EBD Group

EBD Group’s mission is to help collaborations get started across the life science value chain. Our range of partnering conferences has grown to become the largest and most productive conference portfolio in the industry. Each one of our landmark events, held in key life science markets around the world, is powered by our state-of-the-art partnering software, partneringONE, that enables delegates to efficiently identify and engage with new opportunities via one-to-one meetings. Today, our events and those of our sister organization, LSX, (BIO-Europe, BIO-Europe Spring®, LSX Europe, Biotech Showcase™, LSX USA, Investival Showcase USA, ChinaBio® Partnering Forum, Asia Bio Partnering Forum, LSX Nordic, BioEquity Europe, Investival Showcase EU, and the European Lifestars Awards) annually attract more than 15,000 senior life science executives who engage in over 50,000 one-to-one partnering meetings. These vital one-to-one engagements are the wellspring of deals that drive innovation in our industry.

EBD is an Informa company. Informa is a leading international Live B2B Events, B2B Digital Services, and Academic Markets Group. Informa is a member of the FTSE 100 and works in over 30 countries.

For more information, please visit: https://informaconnect.com/partnering-investment-strategy/

Media Contacts: 
MC Services AG
+49 89 2102280
contact@mc-services.eu

Informa 
Paul Gilbertson 
paul.gilbertson@informa.com

Corporate News

Darwin AG Announces Preliminary Group Revenue for 2025 and Confirms Strategic Growth Trajectory

Munich, February 25, 2026 – Darwin AG (ISIN DE000A3C35W0) today announces its preliminary consolidated revenue for the 2025 financial year. Based on preliminary financial figures, the company generated consolidated revenue of approximately €55 million in the 2025 financial year (previous year: €25.3 million). This corresponds to revenue growth of approximately 117% compared to the previous year.

In addition, the company expects to report a positive consolidated net result.

“We are very satisfied with the development of consolidated revenues in the 2025 financial year. The preliminary revenue figures underline the operational strength of our group,” comments CEO Dr. Daniel Wallerstorfer. “With the products of our wholly owned subsidiary Novogenia GmbH, we have gained international visibility for our comprehensive genetic analyses and the personalized nutritional supplements based on them. The strategic partnerships with 10X Health (USA) and M42 (Abu Dhabi) form the foundation for a new phase of scaling. For Darwin AG, we see significant potential for sustainable value creation through the implementation of these major projects and additional initiatives.”

The full audited consolidated financial figures for 2025 will be published together with the 2025 Annual Report on May 12, 2026.

About Darwin AG

The “Darwin Group” (i.e. Darwin AG including its subsidiaries), headquartered in Munich (Germany), is a European healthcare company, particularly active in the field of human genetics and the development of personalized products based on genetic analysis. The genetic analyses conducted in the company’s own laboratory are used in the diagnosis, treatment, and prevention of diseases, as well as in the production of individually tailored nutritional supplements and cosmetics. Darwin also acts as a partner to physicians, therapists, pharmacists, nutritionists, and fitness trainers, helping to ensure treatment or support that is as optimal as possible for the patient’s or client’s needs by analyzing their respective genetic predispositions. In addition, Darwin holds investments in innovative companies in the biotech, healthcare, and life sciences sectors.

Contact:

BRAIN Biotech announces 3M 25/26 results and breakthrough at BioIncubator company SolasCure: Aurase Wound Gel showing strong clinical evidence of superior debridement and healing in chronic wounds

• Aurase shows dual action on chronic wound debridement and healing
• SolasCure preparing fund raising for clinical phase 2b/3
• Sequential growth forecasted in the next quarters for BRAINBiocatalysts

ZWINGENBERG, Germany, February 25, 2026 – BRAIN Biotech AG, a leading provider of specialty enzymes and innovative biosolutions for industry, has published its financial figures for the first three months of the fiscal year 2025/26.

BRAIN Biotech Group generated Q1 revenue of € 11.9 million compared to € 13.1 million in the same period of the previous year, a decrease of 9.0 %. The group strongly improved the adjusted EBITDA to € 0.3 million from € -0.7 million in the same period last year, reflecting the strong performance of the BRAINBioIncubator segment. The BRAINBioIncubator segment benefitted from a milestone income of € 1.0 million from the deucrictibant program. The core segment BRAINBiocatalysts had the expected slow start to the year but is forecasted to show sequential growth over the next quarters.

The company today announced very positive news on its BRAINBioIncubator participation SolasCure. SolasCure is an independent clinical development company in which BRAIN Biotech holds a 35 % stake and additional production rights to the active pharmaceutical ingredient (API) tarumase. SolasCure has now successfully completed an extension study of Phase 2a clinical development. The treatment of chronic wounds with Aurase^® Wound Gel which combines a hydrogel with the enzymatic active ingredient tarumase shows both a 22 times more effective wound debridement and a 7 times accelerated healing compared to the current standard of care in the control group. SolasCure sees a total addressable market for the advanced treatment of chronic wounds of around US$ 4.3 billion in the US alone.

With this positive clinical data, SolasCure is now seeking a larger financing round to secure funding for the next steps in clinical development. Adriaan Moelker, CEO BRAIN Biotech, comments: “I am really thrilled by the clinical data the SolasCure team has been able to demonstrate. There is a large global need for innovation in advanced wound care. Aurase Wound Gel has demonstrated to accelerate wound debridement and healing at the same time and has therefore the potential to become a best-in-class first line treatment for chronic wounds with a large addressable market. We at BRAIN Biotech are very proud to have invented this enzyme and to be an active partner in its commercialization.”

Development of the segments

Revenues in the core segment BRAINBiocatalysts (enzymes, microorganisms and ingredients) decreased by 16.3 % from € 11.9 million to € 10.0 million in the reporting period. This decrease is largely attributable to lower sales of baking enzymes and to the beverage industry. The company is currently commissioning a new state-of-the-art joint production site in the Netherlands. The move and combination of production sites to and within the Netherlands was one root cause of lower sales in the quarter next to lower general customer demand. BRAIN Biotech Group expects to finalize commissioning of the new plant during Q2 2025/26. Adjusted EBITDA in the BRAINBiocatalysts segment decreased from € 0.8 million to € 0.5 million, mainly due to lower revenues and negative product mix effects. The company is forecasting sequential revenue growth for the BRAINBiocatalysts segment over the next quarters after the soft start in Q1.

Revenues within the BRAINBioIncubator segment (research-intensive R&D projects with industrial partners and own projects) rose strongly by € 0.7 million to € 1.9 million from € 1.2 million in the previous year. The company has been able to harvest a major milestone payment of € 1.0 million from the deucrictibant project for the treatment of hereditary angioedema. Milestone income in combination with lower personnel costs significantly improved adjusted EBITDA to € 0.7 million (€ – 0.7 million last year).

The BRAIN Biotech Holding mainly includes personnel expenses and other expenses for Group administration, further development of the BRAIN Biotech Group, stock exchange listing costs, group financing and M&A activities. The adjusted EBITDA for the holding was slightly lower at € -0.9 million compared to the previous year and fully within the budget planning.

Outlook

For the financial year 2025/26, BRAIN Biotech AG maintains its outlook for the core segment BRAINBiocatalysts with expected sales around last year’s level and an associated adjusted EBITDA margin of around 10 %. The company upgrades its guidance for the segment BRAINBioIncubator to a positive adjusted EBITDA (previously around break-even). It maintains its view that revenues in this segment are expected to grow markedly, targeting around € 5 million in the financial year.

Key financial data for the first three months of the fiscal year 2025/26

1 Revenues + change in inventories + other income including R&D grants

2 The reconciliation from adjusted to unadjusted EBITDA can be found in the 3M report for the period ended December 31^st, 2025

Further information

BRAIN Biotech AG 3M Report 2025/26:
https://www.brain-biotech-group.com/en/investors/financial-publications-calendar/financial-reports/

Financial Calendar:

https://www.brain-biotech-group.com/en/investors/financial-publications-calendar/financial-calendar/

+++

Contact Media

Dr. Stephanie Konle, PR & Corporate Communications
Phone: +49 6251 9331-70
Email: stk@brain-biotech.com

Contact Investor Relations

Martina Schuster, Investor Relations
Phone: +49 6251 9331-69
Email: ms@brain-biotech.com

BRAIN Biotech

The BRAIN Biotech Group is a leader in researching, developing, and producing specialty enzymes, focusing on the food and life sciences industries. In addition, the group develops microbial production strains and scalable bioprocesses for the economic production of specialty enzymes and other proteins. BRAIN Biotech also offers customized biological solutions to the industry for more sustainable products and efficient processes.

BRAIN Biotech AG is the parent company of the BRAIN Biotech Group. The company´s activities are divided into two business segments: BRAINBiocatalysts (development, production, and distribution of specialty enzymes, microorganisms, and ingredients) and BRAINBioIncubator (research-intensive development projects and pharmaceuticals).

BRAIN Biotech operates its own fermentation facilities in the UK and has additional production sites in continental Europe and the US. BRAIN Biotech AG has been listed on the Frankfurt Stock Exchange since February 9, 2016 (Ticker symbol: BNN; ISIN: DE0005203947 / WKN: 520394). In the 2024/25 fiscal year, the group generated revenue of € 49.6 million with around 280 employees. For more information, visit: www.brain-biotech-group.com.

The BRAIN Biotech Group on social media and on the internet:

BRAIN Biotech Gruppe

Web: www.brain-biotech-group.com

LinkedIn: https://www.linkedin.com/company/brainbiotech

Threads: https://www.threads.net/@brainbiotechag

Bluesky: https://bsky.app/profile/brain-biotech-group.com

X: https://x.com/BRAINbiotech

Youtube: https://www.youtube.com/channel/UCS33HJqku674X22UQ8QIsyg

Biocatalysts Ltd (Production, Distribution)

Website: https://www.biocatalysts.com/

LinkedIn: Biocatalysts Ltd on LinkedIn / BRAIN-Biocatalysts Life Science Solutions on LinkedIn

BRAIN Biotech Zwingenberg (Technologies & R&D Services)

Website: www.brain-biotech.com

LinkedIn: BRAIN Biotech Technologies & Services

AnalyticonDiscovery (R&D)

Web: https://ac-discovery.com/

LinkedIn: https://www.linkedin.com/company/analyticon-discovery/

Disclaimer

This press release contains forward-looking statements. These statements reflect the current views, expectations, and assumptions of the management of BRAIN Biotech AG, and are based on information currently available to the management.

Forward-looking statements are no guarantees of future performance, and entail both known and unknown risks as well as uncertainties that could cause actual results, performance or events to differ materially from those expressed or implied in such statements. Numerous factors exist that could influence the future performance of and future developments at BRAIN Biotech AG and the BRAIN Biotech Group. Such factors include, but are not limited to, changes in the general economic and competitive environment, risks associated with capital markets, currency exchange rate fluctuations, changes in international and national laws and regulations, in particular with respect to tax laws and regulations, as well as other factors.

BRAIN Biotech AG does not undertake any obligation to update or revise any forward-looking statements.

Pentixapharm Receives FDA “Study May Proceed” Letters for Dual Theranostic INDs in CXCR4-Based Hemato-Oncology Program

• U.S. Investigational New Drug (IND) applications for radiotheranostic pair PentixaFor and PentixaTher became active following completion of the FDA 30-day review period.
• Proposed phase I/II trial designed to confirm the suitability of CXCR4-directed radiotherapy for bone marrow conditioning in patients undergoing stem cell transplant.
• Overall aim is to complement or reduce conventional chemotherapy for acute myeloid leukemia (AML) and multiple myeloma (MM) patients.

Berlin, Germany – February 25, 2026 – Pentixapharm Holding AG (Frankfurt Prime Standard: PTP), an advanced clinical-stage biotech developing novel radiopharmaceuticals, today announced that the U.S. Food and Drug Administration (FDA) has completed its 30-day safety review of two Investigational New Drug (IND) applications for the Company’s CXCR4-targeted theranostic program in hemato-oncology and confirmed that the proposed clinical study may proceed.

The two IND submissions support the single PENTHERA Phase I/II protocol, which evaluates the combined use of PentixaFor imaging and [⁹⁰Y]Y-PentixaTher as targeted bone marrow conditioning prior to stem cell transplantation in patients with acute myeloid leukemia (AML) and multiple myeloma (MM).

Hematopoietic Stem cell transplantation remains the only potentially curative treatment option for many patients with these hematologic malignancies, yet conventional conditioning regimens rely on highly toxic chemotherapy and/or total body irradiation. Pentixapharm’s CXCR4-directed radiopharmaceutical approach is designed to enable more biologically targeted conditioning while delivering antitumor activity with precision.

In Europe and the US alone, AML and MM together account for more than 25,000 stem cell transplantations annually, each requiring a conditioning regimen prior to transplant.

“The U.S. INDs provide important regulatory validation of our CXCR4-targeted approach and support its advancement in the stem cell transplant setting, combining PentixaFor imaging with [⁹⁰Y]Y-PentixaTher,” said Dirk Pleimes, CEO of Pentixapharm. “AML and MM are significant hematologic malignancies where transplantation remains central to treatment. We believe that targeted bone marrow conditioning has the potential to offer a differentiated strategy within this established chemotherapy-based paradigm. This regulatory milestone also builds on our ongoing investigator-initiated clinical studies in AML in Europe.”

The Company will determine the timing of future clinical studies under the IND in accordance with its broader portfolio prioritisation and resource planning.

About Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)
AML and MM are serious hematologic malignancies associated with high relapse rates and ongoing unmet medical need. In eligible patients, stem cell transplantation represents a potentially curative treatment option. Conditioning therapy prior to transplantation, designed to reduce residual disease and prepare the bone marrow for engraftment, is an established component of the procedure. Conventional conditioning regimens typically rely on intensive chemotherapy and/or external beam radiation, which act systemically and may be associated with significant off-target toxicity.

About Pentixapharm

Pentixapharm is an advanced clinical-stage biotech expanding the boundaries of radiopharmaceuticals. Headquartered in Berlin, Germany, the company develops precision diagnostics and therapeutics in oncology and cardiology to transform patient care. Its clinical pipeline is anchored by CXCR4-targeted PET-CT programs, including a Phase 3-ready candidate for the improved diagnosis of hypertensive patients with primary aldosteronism, which is intended to enable targeted treatment of the underlying causes of hypertension. CXCR4-based developments also include pioneering therapeutic programs in hematological cancers. Furthermore, Pentixapharm is advancing a next-generation antibody platform targeting CD24, an emerging immune-checkpoint marker over-expressed in multiple hard-to-treat cancers. Complemented by CXCR4 and CD24 intellectual property protection and a reliable isotope supply chain, Pentixapharm is poised to deliver meaningful patient benefit and sustainable growth in one of the fastest-growing areas of precision medicine.

Pentixapharm Investor and Media Contact
ir@pentixapharm.com

#FutureFresenius: REJUVENATE in action – Delivering accelerated performance for long-term value creation; 2025 yet another year of strong delivery

FY/25 – Strong organic revenue and excellent Core EPS growth; REJUVENATE phase spurs profitable growth, drives stronger balance sheet, and creates significant value.

• Group revenue¹ at €22,554 million with organic growth of 7%^1,2 reflecting the consistent execution across Fresenius Kabi and Fresenius Helios.
• Group EBIT¹ at €2,595 million with 6%³ growth in constant currency driven in particular by Fresenius Kabi’s Growth Vectors and the strong performance of Fresenius Helios in Spain; Group EBIT margin¹ at 11.5% despite significant headwinds.
• Core EPS^1,4 increased by 12%³ in constant currency to €2.87 based on strong operating results and significantly decreased interest expense.
• Structural EBIT margin ambition increased for Fresenius Kabi to 17 to 19% (previously 16 to 18%)
• Constant currency Core EPS growth^1,4 established as new guidance metric is expected to be in the range of 5 to 10% in FY/26; organic revenue growth² projected to be in the range of 4 to 7% in FY/26.
• Net debt/EBITDA ratio improved by 30 bp to 2.7x^1,5, well within the self-imposed target corridor of 2.5 to 3.0x; driven by cash flow delivery leading to significant debt reduction.
• Dividend proposal of €1.05 per share; year-on-year increase of 5%, in line with the Company’s dividend payout ratio of 30 to 40%.

Q4/25 – Closing the year with an outstanding quarter; excellent organic revenue and EBIT growth; excellent operating cashflow.

• Group revenue¹ at €5,875 million with organic growth of 9%^1,2 driven by contributions from both, Fresenius Kabi and Fresenius Helios.
• Group EBIT¹ at €713 million with constant currency growth of 13%³ on the back of the continued powerful operating performance at Fresenius Kabi and the expected strong acceleration at Fresenius Helios; Group EBIT margin¹ improved by 40 bp to 12.1%.
• Core EPS^1,4 growth in constant currency of 16%³ further accelerated to €0.78, driven by consistent operating strength and lower interest expenses.
• Operating cashflow of €1,340 million, a year-on-year increase of 36% driven by disciplined capex spending and focus on net working capital at Fresenius Kabi, and Fresenius Helios successfully driving receivables collection.

Michael Sen, CEO of Fresenius: “2025 was a pivotal year for Fresenius. With disciplined execution of our #FutureFresenius strategy and a strong performance from Team Fresenius, we met our upgraded full-year guidance by delivering another quarter of competitive growth, increasing organic revenue by 9%, EBIT by 13% and Core EPS by 16% at constant currency. 2025 capped a year of continued momentum across the Company: We further strengthened the balance sheet, and upgraded our guidance, while preparing the business through targeted investment for the next phase of growth. All of this leads to a proposed dividend of €1.05 per share, underscoring our commitment to creating shareholder value.

With #FutureFresenius we have transformed our Company, positioning ourselves to deliver future success in a new world order. Looking ahead, we enter 2026 with strong foundations and clear priorities. We are confident in our ability to deliver profitable, sustainable growth with the guidance of organic revenue growth of 4% to 7% and constant currency Core EPS growth of 5% to 10%, while continuing to create long term value across the healthcare ecosystem for patients, customers, partners, and shareholders.”

Guidance for Fiscal Year 2026¹

Fresenius Group⁶: organic revenue growth² in the range of 4% to 7%; constant currency Core EPS^1,4 growth expected in the range of 5% to 10%;
EBIT margin⁹ of ~11.5%.

Fresenius Kabi⁷: organic revenue growth³ in the mid- to high-single-digit percentage range; EBIT margin¹ of 16.5% to 17.0%.
Structural EBIT margin¹ ambition raised to 17% to 19% (previously 16% to 18%) following Kabi’s rigorous strategy execution leading to consistent margin expansion over the past several years.

Fresenius Helios⁸: organic revenue growth in the mid-single-digit percentage range; EBIT margin of 10.0% to 10.5%.

Assumptions to guidance: The company acknowledges that the prevailing trends of fast-moving macroeconomic and geopolitical environment continue, resulting in increased volatility and a higher level of operational uncertainty. The guidance does not take into account potential extreme scenarios that could affect the company, its peers, and the healthcare sector as a whole. Potential implications of the United States Supreme Court ruling as of February 20, 2026, are currently being evaluated but cannot be fully assessed at this stage and are hence not reflected in the FY/26 guidance. 

Dividend proposal of €1.05 per share reflects capital allocation priorities

Fresenius remains fully commitment to delivering attractive shareholder returns. For fiscal year 2025, the Company will propose a dividend of €1.05 per share. This corresponds to a payout ratio of 37%, at the upper half of the 30% to 40% range of core net income^1,4, as specified in the Fresenius Financial Framework.
 

Fresenius Group – Business development FY and Q4/2025

FY/25: Strong performance despite significant macroeconomic headwinds; twice upgraded guidance delivered.

Organic revenue¹ grew 7%² reaching the top-end of the 5% to 7% guide while the 6%³ constant currency Group EBIT growth before special items secured the midpoint of the guided range of 4% to 8%. The Company achieved this despite significant headwinds including the impact from the absence of energy relief funding at Fresenius Helios, the Volume Based Procurement (VBP) of the nutrition product Ketosteril in China at Fresenius Kabi, as well as FX effects and U.S. tariffs.

Q4/25: Closing the year with an outstanding quarter which led to an increase of Group organic revenue¹ growth of 9%² and revenues reaching €5,875 million.

Group EBIT before special items amounted to €713 million, a significant acceleration with an increase of 13%³ in constant currency fuelled by Fresenius Kabi’s continued powerful operating performance and the expected strong development at Fresenius Helios. The strong acceleration at Helios is due to the very strong top-line development and was supported by strong execution on the Performance Program in Q4/25 as well as the positive effects from the surcharge on invoices of publicly insured patients recognized under other operating income. At Kabi, the operating leverage and additional productivity gains more than compensated the impact from the VBP of the nutrition product Ketosteril in China, and some targeted investments.

Group EBIT margin¹ improved by 40 bp to 12.1%.

Group Core net income^1,4 increased by 16%³ in constant currency to €440 million strongly outpacing revenue growth. The good operating performance of both, Fresenius Kabi and Fresenius Helios, further productivity gains as well as the decreased year-over-year interest expenses drove this performance.

Group Core earnings per share^1,4 rose by 16%³ in constant currency to €0.78.

Operating Companies – Business development FY and Q4/25

Fresenius Kabi

FY/25: Consistent financial performance delivered over the course of the year with excellent organic revenue growth of 7% at the top-end of the structural growth band and an EBIT margin expansion of 70 bps to 16.4%.

Q4/25: Strong finish to the year with organic growth well above the structural growth band of 4% to 7%; Growth Vectors driving the performance headed by continued Biopharma strength; EBIT margin reflects targeted investments, and year-end effects.

Organic revenue growth of 10%² in Q4 driven by the Growth Vectors and led by Biopharma with strong product roll-outs; revenue rose to €2,214 million, making it the highest quarterly revenue amount in Fresenius Kabi’s history; growth as reported was significantly impacted by currency translation effects, primarily from the US Dollar and the Argentinian Peso.

• Growth Vectors with 16% organic revenue² growth; Biopharma 97%, MedTech 5%, and Nutrition 5%
  • Biopharma revenue: €265 million, mainly driven by the tocilizumab biosimilar Tyenne ramp up in Europe and the U.S.; uptake of Otulfi with first sales from the exclusive distribution agreement with CivicaScript in the U.S.
  • MedTech revenue: €425 million with broad-based growth across all regions and segments, Transfusion & Cell Therapy (TCT) and Infusion and Nutrition Systems (INS) both showed solid growth.
  • Nutrition revenue: €602 million driven by strong underlying growth in Europe and Latin America; more than offset the impact from the VBP tender on nutrition product Ketosteril in China.
• Pharma revenue: €922 million, organic revenue increased by 2%² driven by Europe, with good volumes and price mix; U.S. volume growth more than compensated for pricing pressures.
• EBIT¹ of Fresenius Kabi increased to €349 million or 7%³ at constant currency. The performance reflected the operating leverage and the benefit of productivity gains that more than offset the impact of the Ketosteril tender in China and the adverse impact from U.S. tariffs, particularly in MedTech. The performance in the quarter also reflected targeted investments. The EBIT margin¹ was 15.8%.
• EBIT¹ of the Growth Vectors increased by 19%³ in constant currency and amounted to €199 million; EBIT margin¹ improved by 70 bps to 15.4%, making further progress toward Kabi’s structural margin band target.
• EBIT¹ of Pharma increased 2%³ in constant currency to €189 million driven by Europe and the U.S. as well as by ongoing cost efficiencies. EBIT margin¹ at 20.5%.

Fresenius Helios

FY/25: Fresenius Helios delivered organic revenue growth of 7% driven by solid activity growth and favourable pricing in Germany and Spain;
EBIT margin¹ of 9.8% consistent with the target for FY/25.

Q4/25: Fresenius Helios with very strong organic revenue growth and outstanding year-on-year margin improvement. 

8% organic revenue growth in Q4 mainly driven by year-over-year activity levels increase at both, Helios Germany and Helios Spain, and positive pricing; revenue increased by 8% in constant currency to €3,546 million.

• Helios Germany’s organic revenue growth at 6%, reflecting good admission growth and positive pricing; revenues at €2,055 million.
• Helios Spain with organic revenue growth of 11% to €1,491 million driven by strong activity levels and end-of-year payor settlements.
• EBIT¹ of Fresenius Helios at €416 million with 22% growth at constant currency. The acceleration at Helios reflects the very strong top-line development and was fuelled by the significant ramp up of the Performance Program in Q4/25 and the positive effects from the surcharge on invoices of publicly insured patient in Germany recognized under other operating income. EBIT margin¹ of Fresenius Helios improved by 130 bp to 11.7%.
• EBIT¹ of Helios Germany increased by 52% to €194 million reflecting the significant ramp up of the Performance Program in Q4/25 and the positive effects from the surcharge on invoices of publicly insured patient in Germany; EBIT margin¹ improved by 280 bp to 9.4% compared to Q4/2024.
• EBIT¹ of Helios Spain increased by 6% in constant currency to €224 million; EBIT margin¹ at 15.0% reflects some year-end effects as well as the good topline development.
• Helios Performance Programme delivering substantial cost savings in Q4/25 adding up to the expected roughly €100 million contributions in FY/25.

Footnotes

¹ Before special items

² Organic growth rate adjusted for accounting effects related to Argentina hyperinflation

³ Growth rate adjusted for Argentina hyperinflation

⁴ Excluding Fresenius Medical Care

⁵ At average exchange rates for both net debt and EBITDA; pro forma closed

 acquisitions/divestitures, including lease liabilities, including Fresenius Medical Care

 dividend, net debt adjusted for the valuation effect of the exchangeable bond

⁶ 2025 base: €22,554 million (revenue), €2.87 (Core EPS^1,4)

⁷ 2025 base: €8,612 million (revenue) and €1,413 million (EBIT)

⁸ 2025 base: €13,550 million (revenue) and €1,328 million (EBIT)

⁹ This metric (EBIT margin) is provided solely for modelling purposes and does not form part of the official guidance; 2025 Base: €2,595 million

Group figures Q4 and FY/25

Conference call and Audio webcast

As part of the publication of the Q4 and FY 2025 results, a conference call will be held on February 25, 2026 at 1:30 p.m. CET / 7:30 a.m. EST. All investors are cordially invited to follow the conference call in a live audio webcast at https://www.fresenius.com/investors. Following the call, a replay will be available on our website. 

Press Contact

Friederike Segeberg                                     Timo Lindemann
Group Communications                                Group Communications
Fresenius SE & Co. KGaA                            Fresenius SE & Co. KGaA
Else-Kröner-Straße 1                                    Else-Kröner-Straße 1
61352 Bad Homburg, Germany                    61352 Bad Homburg, Germany
M +49 (0) 175 9627751                                M +49 (0) 151 15515324
Friederike.Segeberg@fresenius.com           Timo.Lindemann@fresenius.com 

Note on the presentation of financial figures

• If no timeframe is specified, information refers to Q4/2025.
• Consolidated results for Q4 and FY 2025 as well as for Q4 and FY 2024 include special items. An overview of the results for Q4 and FY 2025 – before and after special items – is available on our website.
• Growth rates in constant currency of Fresenius Kabi are adjusted. Adjustments relate to the hyperinflation in Argentina. Accordingly, constant currency growth rates of the Fresenius Group are also adjusted.
• Information on the performance indicators is available on our website at https://www.fresenius.com/alternative-performance-measures.

Fresenius SE & Co. KGaA (Frankfurt/Xetra: FRE) is a global healthcare company headquartered in Bad Homburg v. d. Höhe, Germany. In the 2025 fiscal year, Fresenius generated €22.6 billion in annual revenue. Fresenius currently counts over 178,000 employees. The Fresenius Group comprises the operating companies Fresenius Kabi and Fresenius Helios as well as an investment in Fresenius Medical Care. With around 140 hospitals and countless outpatient facilities, Fresenius Helios is the leading private hospital operator in Germany and Spain, treating around 27 million patients every year. Fresenius Kabi’s product portfolio touches the lives of 450 million patients annually and includes a range of highly complex biopharmaceuticals, clinical nutrition, medical technology, and intravenous generic drugs and fluids. Fresenius was established in 1912 by the Frankfurt pharmacist Dr. Eduard Fresenius. After his death, Else Kröner took over management of the company in 1952. She laid the foundations for a global enterprise that today pursues the goal of improving people’s health. The largest shareholder is the non-profit Else Kröner Fresenius Foundation, which is dedicated to advancing medical research and supporting humanitarian projects.

For more information visit the Company’s website at www.fresenius.com.

Visit our media center: www.fresenius.com/media-center

This release contains forward-looking statements that are subject to various risks and uncertainties. Future results could differ materially from those described in these forward-looking statements due to certain factors, e.g. changes in business, economic and competitive conditions, regulatory reforms, results of clinical trials, foreign exchange rate fluctuations, uncertainties in litigation or investigative proceedings, the availability of financing and unforeseen impacts of international conflicts. Fresenius does not undertake any responsibility to update the forward-looking statements in this release.

Fresenius SE & Co. KGaA
Registered Office: Bad Homburg, Germany / Commercial Register: Amtsgericht Bad Homburg, HRB 11852
Chairman of the Supervisory Board: Wolfgang Kirsch

General Partner: Fresenius Management SE
Registered Office: Bad Homburg, Germany / Commercial Register: Amtsgericht Bad Homburg, HRB 11673
Management Board: Michael Sen (Chairman), Pierluigi Antonelli, Sara Hennicken, Robert Möller, Dr. Michael Moser
Chairman of the Supervisory Board: Wolfgang Kirsch