Heidelberg Pharma to Receive Milestone Payment from Partner Huadong for Clinical Study with HDP-101 in China

Heidelberg Pharma AG

/ Key word(s): Miscellaneous

Heidelberg Pharma to Receive Milestone Payment from Partner Huadong for Clinical Study with HDP-101 in China

18.03.2026 / 06:55 CET/CEST

The issuer is solely responsible for the content of this announcement.


PRESS RELEASE

Heidelberg Pharma to Receive Milestone Payment from Partner Huadong for Clinical Study with HDP-101 in China

  • First patient dosed in Huadong’s Phase I study with HDP-101 in China
  • Trial will evaluate safety, tolerability, pharmacokinetics and efficacy of  HDP-101 in Chinese population with plasma cell disorders including multiple myeloma

Ladenburg, Germany, 18 March 2026 – Heidelberg Pharma AG (FSE: HPHA), a clinical-stage biotech company developing innovative Antibody Drug Conjugates (ADCs), today announced that its partner Huadong Medicine Co., Ltd., Hangzhou, China, (SZ 000963; Huadong) has reached a development milestone under the terms of the license agreement from February 2022. With the dosing of the first patient in a clinical study with HDP-101 (INN: pamlectabart tismanitin) in China, a planned milestone payment to Heidelberg Pharma became due and is being processed. Financial details were not disclosed.

The clinical Phase I trial will evaluate the safety, tolerability, pharmacokinetics and efficacy of Heidelberg Pharma’s lead ATAC candidate pamlectabart tismanitin in Chinese population with plasma cell disorders including multiple myeloma. This bridging study is conducted in addition to the existing clinical program with this ATAC to ensure that safety and efficacy of the ATAC is comparable across diverse populations. The study has initiated dosing at 140 µg/kg, a dose level previously shown to be safe and well tolerated in the Caucasian ethnicity.

Dr. Donghzou Jeffery Liu, Chief Executive Officer of Heidelberg Pharma AG, commented: “The start of clinical development in China is an important milestone for us and Huadong, enabling us to test this product candidate not only in Europe and the US but also in Asia. With our unique payload Amanitin we have a clear differentiation in the ADC space. We are confident that pamlectabart tismanitin will demonstrate consistent safety and tolerability in the Chinese population and firmly believe in its therapeutic potential for various patient groups.”

About Heidelberg Pharma

Heidelberg Pharma is the first company to develop cancer therapies using Amanitin, a compound derived from the green death cap mushroom. The biological mechanism of action of the toxin represents a new therapeutic modality and is used as a compound in the Amanitin-based ADC technology, the so-called ATAC technology.

The lead candidate HDP-101 (INN: pamlectabart tismanitin) is a BCMA ATAC in clinical development for multiple myeloma. The candidate has been granted Orphan Drug Designation and Fast Track Designation from the FDA. A second ATAC candidate, HDP-102 is in clinical development stage in Non-Hodgkin Lymphoma. HDP-103 against metastatic castration-resistant prostate cancer and HDP-104 targeting gastrointestinal tumors such as colorectal cancer have completed preclinical development. Heidelberg Pharma is open for partnering.

The company is based in Ladenburg, Germany, and is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol HPHA. More information is available at www.heidelberg-pharma.com

ATAC® is a registered trademark of Heidelberg Pharma Research GmbH.

Contact
Heidelberg Pharma AG
Sylvia Wimmer
Senior Director Corporate Communications
Tel.: +49 6203 1009-1004
E-Mail: investors@hdpharma.com
Gregor-Mendel-Str. 22, 68526 Ladenburg
 
IR/PR-Support
MC Services AG
Katja Arnold (CIRO)
Managing Director & Partner
Tel.: +49 89 210 228-40
E-Mail: katja.arnold@mc-services.eu

This communication contains certain forward-looking statements relating to the Company’s business, which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “will” “should” “future”, “potential” or similar expressions or by a general discussion of the Company’s strategy, plans or intentions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results of operations, financial condition, performance, or achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors and partners are cautioned not to place undue reliance on such forward-looking statements. We disclaim any obligation to update any such forward-looking statements to reflect future events or developments.


18.03.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Heidelberg Pharma AG
Gregor-Mendel-Str. 22
68526 Ladenburg
Germany
Phone: +49 (0)89 41 31 38 – 0
Fax: +49 (0)89 41 31 38 – 99
E-mail: investors@hdpharma.com
Internet: www.heidelberg-pharma.com
ISIN: DE000A11QVV0
WKN: A11QVV
Listed: Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Dusseldorf, Munich, Stuttgart, Tradegate BSX
EQS News ID: 2293188

 
End of News EQS News Service

2293188  18.03.2026 CET/CEST

Cantourage Group SE publishes preliminary figures for 2025 – Revenue rises to EUR 92.8 million

Cantourage Group SE

/ Key word(s): Annual Results/Preliminary Results

Cantourage Group SE publishes preliminary figures for 2025 – Revenue rises to EUR 92.8 million

17.03.2026 / 10:04 CET/CEST

The issuer is solely responsible for the content of this announcement.


  • Significant growth in revenue and earnings
  • International expansion sustainably contributes to positive business development
  • Focus on premium products – increasing price competition in the German low-price segment

Cantourage Group SE (ISIN: DE000A3DSV01) today published preliminary consolidated figures for the 2025 financial year. During the reporting period, the company achieved a significant increase in both revenue and earnings, thereby continuing its dynamic growth trajectory as one of the leading European companies in the field of medical cannabis.

Group revenue increased to EUR 92.8 million in the 2025 financial year (previous year: EUR 50.9 million), representing growth of 82.3% compared to the previous year. Preliminary EBITDA rose to EUR 5.7 million (previous year: EUR 3.8 million).

International expansion supports sustainable earnings quality

Strategic expansion into selected core European markets is increasingly contributing to improved revenue and earnings. Business in the United Kingdom continued to develop positively and accounted for more than 20% of total group revenue in the 2025 financial year.

The positioning of Cantourage Group SE as a pan-European pharmaceutical company is showing increasingly positive effects. Economies of scale, optimized supply chains, and a diversified market presence are stabilizing operational development.

“The European medical cannabis market is increasingly entering a new phase of growth. With our scalable sourcing and distribution platform, exclusive supplier partnerships, and regulatory expertise, we are ideally positioned to benefit from this development. Our focus is on meeting rising demand in our core markets, further expanding our capacities, and establishing Cantourage as one of the leading companies in all relevant European medical markets,” explains Philip Schetter, CEO of Cantourage Group SE.

Price competition in the German market – focus on high-margin premium products

Profitability development in the German market in 2025 was affected by increasing price competition in the low-price segment of medical cannabis flowers. This was driven by a significant increase in product supply in the market, which led to noticeable price pressure, particularly during the summer months.

Cantourage is responding to this market development in Germany by specifically adjusting its product portfolio and placing greater emphasis on higher-margin premium products. In doing so, the company benefits from its international network of selected cultivation partners, with whom Cantourage has established long-term and largely exclusive supply relationships.

From management’s perspective, this strategic direction strengthens the structural profitability of the business in the German market while simultaneously reducing dependence on the increasingly competitive low-price segment.

Note: The figures for the 2025 financial year presented in this release are preliminary, unconsolidated, and unaudited. The audited consolidated financial statements for 2024 are available at: https://www.cantourage.com/investoren#konzernabschluesse

 


17.03.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Cantourage Group SE
Feurigstraße 54
10827 Berlin
Germany
E-mail: info@cantourage.com
Internet: https://www.cantourage.com/
ISIN: DE000A3DSV01
WKN: A3DSV0
Listed: Regulated Unofficial Market in Dusseldorf, Frankfurt (Scale), Munich, Stuttgart, Tradegate BSX
EQS News ID: 2292732

 
End of News EQS News Service

2292732  17.03.2026 CET/CEST

Medartis builds on momentum with 16% organic sales growth and core EBITDA margin exceeding 18%

 ​​​​​FULL-YEAR 2025 KEY FINANCIALS

 

in CHF million, rounded

 

FY 2025

 

 

FY 2024

 

Organic growth1
of core business

 

Reported

Non-core
items2

Core

Reported

Non-core
items2

Core

in CHF

at CER

Net sales

269.3

(3.2)

266.1

224.8

(5.2)

219.6

12.0%

15.7%

Gross profit

204.3

11.3

215.6

178.7

3.1

181.7

 

 

EBITDA

51.5

(2.6)

48.8

48.0

(6.3)

41.7

 

 

EBIT

26.0

(1.5)

24.5

7.9

12.9

20.8

 

 

Net profit / loss

9.3

(3.2)

6.1

3.5

7.9

11.4

 

 

 

 

 

 

 

 

 

 

 

Margins in % of sales

 

 

 

 

 

 

Core change as
%-points (PP)

Gross profit

75.9%

 

81.0%

79.5%

 

82.8%

(1.7 PP)

(1.1 PP)

EBITDA

19.1%

 

18.4%

21.4%

 

19.0%

(0.6 PP)

0.6 PP

EBIT

9.7%

 

9.2%

3.5%

 

9.5%

(0.2 PP)

1.2 PP

Basel, 17 March 2026: Medartis Holding AG (MED:SW), a leading orthopaedic company specialising in head and extremity surgery, today reported total sales of CHF 269.3 million for the full year 2025, representing growth of 24.2% at constant exchange rates (CER). Organically, sales rose 15.7% (2024: 11.7%). EMEA was the principal growth driver, advancing by 18.0% and gaining further market share. The strong topline growth enabled Medartis to meet its initial EBITDA margin guidance despite adverse currency effects and US customs tariffs.

 

 

Matthias Schupp, CEO of Medartis, comments on the result: “2025 was a transformative year for Medartis and we achieved our goals by increasing organic sales by 15.7% and maintaining our core EBITDA margin at 18.4% despite significant currency and customs burdens. The acquisition of KeriMedical and NeoOrtho establishes the Medartis Group with three distinctive brands and a multi-tier strategy, expanding our addressable market significantly. We have also strengthened our leadership team, restructured our distribution channels in the United States and Japan, and positioned the company for accelerated growth as part of our head-to-toe strategy.”

 

Acquisitions add over CHF 800 million to addressable market, with further upside

Medartis completed two acquisitions during 2025. The KeriMedical partnership, which commenced in 2020, reached completion in July following FDA approval for the flagship TOUCH prosthesis. Medartis now holds 100% ownership of KeriMedical, strengthening the company’s position in arthroplasty and marking its entry into this segment. Separately, Medartis acquired a 51% controlling stake in NeoOrtho, a fast-growing value player in the Brazilian orthopaedic market. The acquisition enables a multi-tier pricing strategy and expands the company’s presence in Latin America. It represents a strategic entry into the estimated CHF 450 million value market segment in the region, which currently accounts for approximately three-quarters of the total market.

 

Together, these transactions expand Medartis’ addressable market by more than CHF 800 million, based on current market estimates in the segments where the company is active; the long-term potential is estimated to be considerably larger as these segments continue to grow and the company expands its geographical reach. Beyond portfolio expansion, they form part of a broader organisational evolution as Medartis transitions from a centralised, Swiss precision-oriented structure to a more decentralised, multi-brand model. This shift is designed to enable the company to compete more effectively across diverse global markets with differing customer needs and competitive dynamics.

 

Strategic step into personalised implants and titanium printing

With the publication of today’s results, Medartis also announced that it has entered an agreement to acquire CADskills, a Belgium-based specialist in personalised implant solutions and titanium printing, two fast-evolving areas in extremity and head (CMF) surgery. The acquisition reinforces Medartis’ strategic focus on more complex clinical applications with custom-made implants — including replacement of the jaw joint[2], implants designed to sit directly on the bone surface for patients with significant bone loss[3], and facial contouring solutions[4]. CADskills holds certification to manufacture class III medical devices — the highest regulatory classification for implants. The company has also developed deep expertise in titanium 3D printing and operates a highly integrated model encompassing design, manufacturing and packaging. These printing capabilities are transferable to other regions in the future, supporting Medartis’ broader geographic expansion.

 

In addition, the acquisition expands Medartis’ upper extremity replacement offerings through the Carpitech™ family, which includes carpal bone arthoplasties, further consolidating Medartis’ position as a market leader in small bone replacement in the hand.

 

CADskills was founded by Prof. Dr mult. Dr Maurice Mommaerts, whose work and research in patient-specific implant design and additive manufacturing has contributed to advancing the field. Following the integration in the Medartis Group, Mr Mommaerts will provide scientific and clinical expertise to support continuity during the expansion phase. The transaction is structured as an upfront payment complemented by sales-based earnout components. Both parties have agreed not to disclose exact financial details. Closing of the transaction remains subject to the fulfilment of certain conditions, including a successful Foreign Direct Investment (FDI) screening in Belgium.

 

 

PERFORMANCE BY REGION AND PRODUCT CATEGORY

 

Core sales
in CHF million

FY 2025
 

FY 2024
 

Change
in CHF

Change at CER

Organic change
at CER

EMEA

155.4

122.8

26.5%

28.5%

18.0%

US1

50.4

47.1

7.0%

13.4%

13.4%

APAC

33.4

31.1

7.3%

14.0%

13.3%

LATAM1

26.8

18.5

44.9%

57.1%

10.4%

Total Group

266.1

219.6

21.2%

25.6%

15.7%

1 The NSI contract manufacturing business and NeoOrtho’s hip business, which was divested in 2025, were classified as non-core.

 

In the EMEA region, core sales rose substantially from CHF 122.8 million in 2024 to CHF 155.4 million in 2025, reflecting growth of 28.5% at constant exchange rates. The acquired KeriMedical business contributed CHF 14.1 million to the topline since its consolidation in July 2025. Organically, sales rose 18.0% (CER). The UK and Spain were the primary contributors to the 18.0% growth. In Germany, the company’s largest market in Europe, results were solid despite some impact from the transition to the new hybrid DRG reimbursement system[5] for lower extremities. This performance enabled the company to capture additional market share in the region, driven by the expansion of its elbow portfolio, KeriMedical product sales, and greater territorial coverage thanks to a strengthened sales team. The KeriMedical business, currently distributed directly in three markets, accounted for one quarter of regional growth.

The 2025 EMEA performance surpassed expectations. Medartis secured a significant tender in Saudi Arabia and established market access in Malta and the Baltic countries. In Switzerland, the company introduced its new Hand 2 portfolio, strengthened its presence in the French-speaking region, and benefitted from a substantial CMF contract with the region’s largest university clinic.

 

 

Core sales
in CHF million

FY 2025
 

FY 2024
 

Change
in CHF

Change
at CER

Organic change
at CER

Upper Extremities

179.9

148.2

21.4%

25.7%

15.7%

Lower Extremities

47.3

40.7

16.4%

21.0%

15.1%

CMF and Others1

38.8

30.7

26.4%

31.3%

16.8%

Total Group

266.1

219.6

21.2%

25.6%

15.7%

1 The NSI contract manufacturing business and NeoOrtho’s hip business, which was divested in 2025, were classified as non-core.

 

Fundamental changes completed in the US

Medartis’ core US business achieved organic growth of 13.4% at constant exchange rates. Despite a weakening US Dollar, which reduced reported sales by over 6%-points, sales exceeded the CHF 50 million threshold for the first time in the company’s history. The declining contract manufacturing business from the former NSI contributed CHF 1.8 million in sales to total sales, down from CHF 5.2 million in 2024.

 

Growth moderated in H2 primarily due to the strategic sales channel optimisation, during which the company replaced approximately half of its 57 distribution partners to achieve greater brand and product exclusivity in operating theatres. Following the optimisation, the company now operates with 65 distribution partners. Mid-year, the company terminated its relationship with its largest distribution partner in Florida, accounting for nearly 10% of US sales, to address fundamental issues that would have constrained future growth in the region. The affected territories were refilled rapidly and coverage was expanded through five new distributors across Florida, with complete integration expected within 12 months from the onset of the transition. The company also appointed a new regional sales manager for the Southeast region Orlando and Tampa, positioning itself to capitalise on its first US training centre in Orlando, scheduled to open in Q4. Florida represents a strategically important market for TOUCH, given the population density and age demographics in this retirement state. Excluding the unexpected change in Florida, full-year growth would have reached 18%.

 

Concurrent with these developments, the company launched the Avenger radial head prosthesis and prepared for the commercial rollout of TOUCH in 2026, with initial cases performed by key opinion leaders (KOL) and product registration completed in first-mover centres. The registration process through a value analysis committee (VAC) averages up to four months. To support this important launch, Medartis recruited 10 specialists – comprising field experts and education specialists –and established a train-the-trainer programme designed to train more than 300 surgeons with hands-on support in 2026.

 

A strategic portfolio review resulted in streamlining efforts, including the discontinuation of former NSI products, allowing Medartis to concentrate more resources on upper extremities. The year marked an important transition for the region, with FDA approvals, sales channel optimisation, portfolio streamlining, and leadership changes positioning the company for sustained growth. Management anticipates that TOUCH will serve as a catalyst for business expansion and broaden the surgeon base.

 

Sales in the APAC region increased from CHF 31.1 million in 2024 to CHF 33.4 million in 2025, representing growth of 14.0% (CER) and strong currency headwind. Excluding a minor acquisition effect from KeriMedical sales in the region, organic sales growth reached 13.3% (CER). The Asia Pacific region returned to double-digit growth after two years of challenging market conditions. With the adverse pricing impact ceasing in mid-2025 and fuelled by distal radius growth in excess of 9%, Medartis’ Australian business achieved solid performance. Following the first full year of TOUCH product sales, reimbursement approval remains pending. The clinician feedback for TOUCH is positive and the clinical appetite for the basal thumb prostheses remains high. Medartis anticipates a reimbursement decision in H1, which is expected to establish pricing for CMC1[6] arthroplasty on the ‘Prescribed List’ and stimulate patient flow. The Japanese business recorded growth in excess of 50% as the transition to direct distribution for the upper extremity portfolio progressed. New surgeon acquisition and customer conversion from the former local distributor continued to advance, albeit at a slower pace than initially anticipated. The company’s CMF distributor in Japan exceeded planned targets for the Modus product line, whilst APAC distributors delivered single-digit growth, slightly below internal projections.

 

Latin America recorded a turnaround following the regional sales decline in the prior year. Core regional sales in 2025 advanced by 57.1% (CER) to reach CHF 26.8 million. The acquired NeoOrto business contributed CHF 8.3 million to the topline since its consolidation in May 2025. Organically, sales rose 10.4% (CER). In Mexico, sales grew in the double-digit range, where the company completed a successful reorganisation, transitioning to a direct sales model in Mexico City under the new leadership, which is demonstrating early potential. Distributor sales grew robustly. The Brazilian business stabilised, with a notable improvement in the strategically important CMF segment. Medartis defined a new price positioning for the market and sharpened its commercial focus on the principal urban areas. Through the “Cold Fusion” programme, Medartis is merging the back-office and support functions of Medartis LATAM and NeoOrtho in Curitiba.

 

The consolidation is expected to generate operational synergies from 2027 onwards and provide the scale required to support regional growth. The new production facility progressed according to plan and is set to be inaugurated at the end of March 2026. Beyond this integration, Medartis is preparing market entries with both brands in Colombia, Argentina, and Chile during 2026 and 2027. The Latin America strategy is intended to serve as a template for entering other value markets in the future.

 

FINANCIAL PERFORMANCE

 

This media release and other investor and financial press communications include Alternative Performance Measures (APMs), which exclude one-time effects and M&A-related intangible asset amortisation to provide a clearer view of the company’s underlying operating performance. Medartis management uses these metrics to assess Medartis’ financial and operational performance, providing a complementary perspective to standard financial figures as defined by IFRS. To derive the core result for 2025, the following items were excluded from the reported IFRS figures.

 

  • Under ‘non-core business,’ the negative gross profit contribution of CHF 1.3 million from the US contract manufacturing business and the NeoOrtho hip business were excluded from the core results. The former is scheduled for phase-out in the near term, while the latter was divested in H2.
  • Transaction costs of CHF 0.6 million, recorded in general and administrative expenses, relate to the NeoOrtho and KeriMedical acquisitions. The transition of the Swiss pension fund from an insurance-based model to a collective foundation required adjustments to asset and liability recognition under IAS 19, resulting in additional past service costs of CHF 6.6 million. These were classified under ‘others’ and affected both COGS and OPEX. A further CHF 3.0 million was recorded for product write-offs and a legal settlement following the strategic portfolio review and discontinuation of former NSI products.
  • The largest adjustment to the reported IFRS figures related to post ‘M&A effects’, comprising: the amortisation of inventory step-up to fair value of CHF 8.8 million; a revaluation of the historical 49% investment in KeriMedical of CHF 14.5 million; and a release of CHF 8.6 million in contingent consideration liabilities related to the final NSI earn-out payment. The M&A effects together with some smaller items had a positive impact of CHF 13.6 million on reported EBITDA.

 

The following commentary compares the core results for 2025 with those of the prior-year period on a like-for-like basis.

 

In 2025, core gross profit declined by 1.8PP from 82.8% to 81.0%. The gross margin decline reflected unanticipated US tariff-related costs (0.9 PP), foreign exchange headwinds (0.6 PP) and costs associated with capacity expansion across all four manufacturing sites ahead of anticipated demand growth. Manufacturing efficiency improvements provided a partial offset. The premium KeriMedical product portfolio had an accretive effect on the gross margin, whereas the NeoOrtho value business was dilutive owing to lower average selling prices relative to the premium range.

 

Core operating expenses (OPEX) increased at a slower rate than revenue. With OPEX of CHF 194.6 million, the OPEX-to-sales ratio decreased from 73.8% in the prior year to 73.1% in 2025, reflecting disciplined cost management despite continued investment in growth initiatives. Ahead of the FDA approval, the company build-up of the support organisation for the TOUCH rollout in the US and Australia. Excluding the aforementioned non-core elements, and before taxes, D&A and interest, core EBITDA rose from CHF 41.7 million to CHF 48.8 million. The corresponding EBITDA margin declined from 19.0% to 18.4%. This is mainly a result of the lower gross profit margin. The core EBIT margin decreased by 0.2PP to 9.2%, though it improved by 1.2PP on a constant currency basis.

 

The core net result declined from CHF 11.4 million in 2024 to CHF 6.1 million in 2025. This was primarily attributable to the factors outlined above and a lower finance result. In 2025, interest expense on the convertible bond amounted to CHF 3.5 million, with a further CHF 3.3 million in accretion expenses. The higher year-on-year charges reflect the first full-year impact of the convertible bond, which was issued in April 2024 and therefore only affected approximately nine months of the prior-year period (2024 interest expense: CHF 2.5 million). In addition, FX losses of CHF 5.3 million were recorded, mainly related to the depreciation of the US dollar and the Australian dollar. Core income tax expenses of CHF 5.2 million were recorded in 2025, compared to an exceptional income tax credit of CHF 1.0 million in 2024.

 

Operating cash flow increased by CHF 2.7 million to CHF 34.8 million, and free cash flow reached CHF 9.3 million, reflecting CHF 14.4 million in additional capital expenditure compared with the prior year as the company invested heavily in new production machinery in its facilities in the Warsaw, US, Archamps, Besançon, Curitiba and Basel. M&A-related cash outflows totalled CHF 120.8 million, comprising the equity investment in NeoOrtho and the cash consideration as well as the first of three earn-out payments for KeriMedical. At year-end, the company’s cash position stood at CHF 33.0 million (PY: CHF 138.7 million). For further information on the company’s financial performance, please refer to the financial section of the 2025 Annual Report, available on the company’s website.

 

NEW BOARD MEMBER PROPOSED

At the upcoming Annual General Meeting on 23 April 2026, shareholders will be asked to elect Yang Xu to the Board of Directors. Ms Xu currently serves as Chief Financial Officer of JDE Peets. Prior to this role, she held the position of CFO at the Straumann Group. She will succeed Jennifer Dean, who has served as a member of the Board and the Finance and Audit Committee since 2024. Ms Dean has decided not to stand for re-election. The Board thanks her for her contributions.

 

FULL-YEAR 2026 OUTLOOK

(barring any unforeseen circumstances)

 

Medartis expects to strengthen its market position in the US in 2026, supported by the continued rollout of KeriMedical’s TOUCH prosthesis, alongside continued progress in Japan and further expansion across Latin America. As the number of surgeons trained on TOUCH in the US increases progressively, regional sales growth is anticipated to be stronger in the second half of the year than in the first. Based on its assumptions, the company expects organic growth in core sales[7] 16% – 18% over the full-year.

 

The company also expects a core EBITDA margin in the high teens (at CER), reflecting planned investments in growth initiatives and ongoing TOUCH rollout in the US and Australia.

 

————————————————————————————————————

Medartis to Host Full-Year 2025 Results Conference with Q&A

Medartis will present its full-year 2025 results today at 10:30 a.m. CET at its headquarters in Basel.
CEO Matthias Schupp and CFO Peter Hackel will host the event. The conference will be held in English. The presentation materials, Annual Report and a recording of the event are available on the Medartis website (https://medartis.com/en/investors#reports).

If you cannot attend in person, use the webcast link to register and follow the slide presentation and submit questions in writing or via the webcast interface.

IMPORTANT DATES AND UPCOMING INVESTOR EVENTS

Date

Event

Broker

Destination

17 March

2025 full-year results publication

 

Basel, hybrid

18 March

Investor meetings

ZKB

Zurich

19 March

Investor meetings

UBS

Geneva

20 March

Investor meetings

Octavian

Frankfurt

24 March

Investor meetings

UBS

Paris

20 April

Investor meetings

Kepler Cheuvreux

New York

21 April

Investor meetings

Kepler Cheuvreux

Montreal

23 April

Annual General Meeting 2025

 

Basel, HQ

11 Mai

Investor meetings

Stifel

London

12 Mai

European Small and Midcap Conference

UBS

London

3-4 June

Medartis Group Visitor Day (FESSH congress)

 

Basel

18 August

2026 half-year results publication

 

Webcast

5-7 November

Swiss Equity Conference

ZKB

Zurich, CH

Legend: Events highlighted in italic are broadcasted online

 

Your contact:

Medartis Corporate Communications

Fabian Hildbrand, Head of Corporate Communications, investor.relations@medartis.com

Andreas Richter, Corporate Communications Manager, corporate.communication@medartis.com

+41 61 633 37 36 / +41 61 633 37 34

 

About Medartis

Founded in 1997 and headquartered in Basel, Switzerland, the Medartis Group is one of the world’s leading manufacturers and providers of medical devices for surgical fixation of bone fractures and joint replacement for upper and lower extremities as well as for the craniomaxillofacial region. The Group has manufacturing sites in Switzerland, the United States, Brazil, and France. Medartis employs approx. 1,400 individuals across 12 countries, with products offered in over 60 countries globally. Medartis is committed to providing surgeons and operating theatre personnel with the most innovative implants and instruments as well as best-in-class service. For more information, please visit www.medartis.com.

 

Disclaimer

This communication does not constitute an offer or invitation to subscribe for or purchase any securities of Medartis Holding AG. This publication may contain certain forward-looking statements and assessments or intentions concerning the company and its business. Such statements involve certain risks, uncertainties and other factors which could cause the actual results, financial condition, performance or achievements of the company to be materially different from those expressed or implied by such statements. Readers should therefore not place reliance on these statements, particularly in connection with any contract or investment decision. The company disclaims any obligation to update these forward-looking statements, assessments or intentions. Furthermore, neither the company nor any of its directors, officers, employees, agents, counsel or advisers nor any other person makes any representation or warranty, express or implied, as to the accuracy or completeness of the information contained herein or of the views given or implied, and accordingly no reliance should be placed thereon.

 


[1],2 This report and accompanying financial documents include alternative performance measures (APMs), referred to as “core” figures, which provide additional insight into Medartis’ underlying performance. Core figures exclude certain one-time, non-recurring and extraordinary items or items related to M&A. The NSI contract manufacturing business and NeoOrtho’s hip business (divested in H2 2025) contributed CHF 3.2 million to total revenue and were classified as non-core. For a detailed overview of all non-core events in the Income Statement, please refer to APM section of the Annual Report. Organic growth is calculated using fixed exchange rates (CER). To ensure fair comparison, it includes the acquired business’s sales in the baseline figures from the date Medartis assumed control.

[2] Temporomandibular joint replacement, TMJR Parametro™

[3] Subperiosteal implants, AMSJI®™ = Additively Manufactured Subperiosteal Jaw Implant

[4] Facial contouring

[5] DRG = Diagnosis-Related Group. Reimbursement is calculated by applying a indication specific multiplier to a standardised base rate.

[6] Thumb osteoarthritis (CMC = carpometacarpal joint arthritis)

[7] “Organic growth” denotes the increase in sales at constant exchange rates (CER), excluding the sales from acquired or sold businesses (i.e. NeoOrtho, KeriMedical) in the baseline. NSI’s contract manufacturing business and divested NeoOrtho hip business were non-core activities.

PolyPeptide publishes invitation to the annual General Meeting 2026

PolyPeptide Group

/ Key word(s): AGMEGM

PolyPeptide publishes invitation to the annual General Meeting 2026

17.03.2026 / 07:00 CET/CEST


Media release

PolyPeptide publishes invitation to the annual General Meeting 2026

Baar, 17 March 2026 – PolyPeptide Group AG (SIX: PPGN), a specialized global CDMO for peptide-based active pharmaceutical ingredients, published today the invitation to the fifth annual General Meeting, which will take place on 8 April 2026 at the Chollerhalle in Zug.

At PolyPeptide Group AG’s (the “Company”) fifth annual General Meeting, which will take place on 8 April 2026 at the Chollerhalle in Zug (the “AGM 2026”), all six current members of the Board of Directors will stand for re-election. Peter Wilden is proposed for re-election as Chair of the Board of Directors, and Philippe Weber and Peter Wilden as members of the Remuneration and Nomination Committee.

Further proposals include, among others, the re-election of the Statutory Auditors and the Independent Proxy as well as the approval of the maximum aggregate amount of compensation of the Board of Directors and Executive Committee. The shareholders will also be asked to approve the Management Report, Statutory Financial Statements, Consolidated Financial Statements and the report on non-financial matters, in each case, for the financial year 2025 as well as the Remuneration Report 2025 in a separate consultative vote.

The invitation to the AGM 2026 with the detailed proposals and explanations can be found on the Company’s website.

Contact

PolyPeptide Group AG      
Corporate Communications   
Lauren Starr      
mediateam@polypeptide.com     
T: +41 43 502 0580     

PolyPeptide Group AG
Investor Relations 
Tim Brandl 
investorrelations@polypeptide.com 
T: +41 43 502 0580 

About PolyPeptide

PolyPeptide Group AG and its consolidated subsidiaries (“PolyPeptide”) is a specialized Contract Development & Manufacturing Organization (CDMO) for peptide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world. PolyPeptide serves a fast-growing market, offering products and services from pre-clinical to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with significant exposure to metabolic diseases, including GLP-1. Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange.

For more information, please visit polypeptide.com.  

@PolyPeptide — follow us on LinkedIn.

Disclaimer

This media release has been prepared by PolyPeptide Group AG and contains certain forward-looking statements that reflect the current views of management. Such statements are subject to known and unknown risks, uncertainties and other factors that may cause actual developments to differ materially from those expressed or implied in this release. PolyPeptide Group AG is providing the information in this release as of this date and, except as required by applicable laws or regulations, does not undertake any obligation to update any statements contained in it as a result of new information, future events or otherwise.


Additional features:

File: Polypeptide Media release AGM 2026 Invitation (English)


End of Media Release


Language: English
Company: PolyPeptide Group
Neuhofstrasse 24
6340 Baar
Switzerland
Phone: +41435020580
E-mail: mediateam@polypeptide.com
Internet: www.polypeptide.com
ISIN: CH1110760852
Valor: 111076085
Listed: SIX Swiss Exchange
EQS News ID: 2292198

 
End of News EQS News Service

2292198  17.03.2026 CET/CEST

Sartorius Stedim Biotech sharpens strategy with biopharma focus and sets new mid-term growth targets

Sartorius Stedim Biotech SA

/ Key word(s): Forecast

Sartorius Stedim Biotech sharpens strategy with biopharma focus and sets new mid-term growth targets

17-March-2026 / 07:03 CET/CEST


Aubagne, France | March 17, 2026

Sartorius Stedim Biotech sharpens strategy with biopharma focus and sets new mid-term growth targets

 
  • Expanding leading position with biopharma customers in attractive growth markets
  • Strengthening competitive edge with focus on high-growth, high-margin core portfolio and emerging businesses
  • New ambitious mid-term targets set clear path for sustained, profitable growth above market
Sartorius Stedim Biotech, a leading provider of innovative technologies for the manufacture of biologics, is sharpening its strong focus on biopharma customers and outlined its updated strategy and new mid-term financial targets ahead of today’s Capital Markets Day, defining a clear trajectory for sustained abovemarket growth.

“Our resilient business model and strong execution over recent years provide an excellent starting point for the next growth phase,” said Dr. René Fáber, Chief Executive Officer of Sartorius Stedim Biotech. “The biopharma industry faces increasing demands for efficiency, scalability and reliability. We want to address these even better by extending our leadership position in core bioprocessing technologies and building future growth platforms in areas such as advanced therapies and process analytics. With this, we aim to continue to outperform our markets and create long-term value for customers, partners, suppliers, employees and shareholders alike.”

Sartorius Stedim Biotech’s refined strategic focus reflects key developments in the biopharmaceutical industry. Biologics account for a growing share of pipelines, approvals, and manufacturing volumes. In 2025, global biopharma revenues surpassed those of traditional therapies for the first time and are projected to reach around 57percent of global pharma sales by 2030. At the same time, the industry is becoming more complex, driven by emerging new modalities and mounting cost pressures on health care systems. 
 

Strategic initiatives: Driving portfolio evolution, customer experience and efficiency
To continue its strong growth momentum and further expand its established market position in this changing environment, Sartorius Stedim Biotech has defined a set of strategic initiatives.

With regard to its product portfolio, the company aims to further strengthen its core business by reinforcing its leadership positions in mission critical applications in process intensification, single-use technologies and analytics. In addition, Sartorius Stedim Biotech plans to further develop select emerging businesses, including process analytical technologies and offerings for advanced therapy solutions – a dynamically growing market that particularly requires continuous innovation.

Beyond its portfolio, Sartorius Stedim Biotech is responding to shifting expectations within the biopharma industry, including shorter lead times, delivery reliability and more streamlined interactions. To support this, the company is putting customers even more firmly at the center of its actions while systematically enhancing operational efficiency across supply chain performance, product quality and service performance.

Mid-term ambition: Above-market organic sales revenue growth and margin expansion

Based on its assessment of future market development, Sartorius Stedim Biotech expects the bioprocessing market to expand at a rate of approximately 8 to 10 percent per year over the medium term. Against this backdrop and building on its leading market position as well as its focused strategy, Sartorius Stedim Biotech introduced a new mid‑term ambition for the period from 2027 onwards. Management expects the company to consistently outgrow its addressable market by around 100 to 200 basis points per year, targeting organic sales revenue growth of 9 to 12 percent per year in constant currencies. At the same time, Sartorius Stedim Biotech is committed to further expanding its profitability: The underlying EBITDA margin1 is expected to increase by approximately 60 to 85 basis points per year, driven by operating leverage, operational improvements and a growing share of high-margin consumables.

1 Sartorius Stedim Biotech publishes alternative performance measures that are not defined by international accounting standards. These are determined with the aim of improving comparability of business performance over time and within the industry.

  • Constant currencies: figures given in constant currencies eliminate the impact of changes in exchange rates by applying the same exchange rate for the current and the previous period
  • Underlying EBITDA: earnings before interest, taxes, depreciation, and amortization and adjusted for extraordinary items

2 EMEA = Europe, Middle East, Africa

This media release contains forward-looking statements about the future development of the Sartorius Stedim Biotech Group. Forward-looking statements are subject to known and unknown risks, uncertainties, and other factors that could cause actual results to differ materially from those expressed or implied by such statements. Sartorius Stedim Biotech assumes no liability for updating such statements in light of new information or future events. Sartorius Stedim Biotech shall not assume any liability for the correctness of this release. The original French press release is the legally binding version.

Forecasts have been prepared based on historical information and are consistent with accounting policies. All forecast figures are based on constant currencies, as in past years. Management points out that the dynamics and volatilities in the industry have increased significantly in recent years. In addition, uncertainties due to the changed geopolitical situation, such as the emerging decoupling tendencies of various countries as well as the trade policy framework conditions, are playing a greater role. This results in higher uncertainty when forecasting business figures.

Further information
Sartorius Stedim Biotech Capital Markets Day

Financial calendar
March 24, 2026 | Annual General Meeting 
April 23, 2026 | Publication of quarterly figures for January to March 2026 
July 23, 2026 | Publication of half-year figures for January to June 2026 
October 22, 2026 | Publication of nine-month figures for January to September 2026

A profile of Sartorius Stedim Biotech

Sartorius Stedim Biotech is a leading international partner of the biopharmaceutical industry. As a provider of innovative solutions, the company based in Aubagne, France, helps its customers to manufacture biotech medications, such as cell and gene therapies, safely, rapidly, and sustainably. The shares of Sartorius Stedim Biotech S.A. are quoted on the Euronext Paris. The company has a strong global reach with manufacturing and R&D sites as well as sales entities in Europe, North America, and Asia. Sartorius Stedim Biotech regularly expands its portfolio through acquisitions of complementary technologies. In 2025, the company generated sales revenue of around 3 billion euros. Currently, more than 10,200 employees are working for customers around the globe.

Visit our newsroom and follow us on LinkedIn.

Contact 
Leona Malorny 
Head of External Communications 
+49 551 308 4067 
leona.malorny@sartorius.com
 


Attachment

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2292110  17-March-2026 CET/CEST

Major Milestone CF PHARMTECH, INC. 2652.HK Announces IND Acceptance for PAH New Drug with a Globally Innovative Improved Mechanism, Marking Another Milestone for Its Precision Drug Delivery Platform

EQS Newswire / 16/03/2026 / 18:08 UTC+8

Focused on developing high-value inhalation therapies for pulmonary hypertension (PAH and PH-ILD), with clinical potential to expand into pulmonary fibrosis indications (PF-ILD, including IPF and PPF).

Suzhou, China, March 13, 2026 — CF PHARMTECH, INC. (HKEX: 2652.HK, hereinafter referred to as “CF PHARMTECH, INC.” or “the Company”) today announced that the National Medical Products Administration (NMPA) has officially accepted the Investigational New Drug (IND) application for ICF001. Independently developed by the Company, ICF001 is an innovative inhalation powder for the treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD). It is classified as a Class 2.1 improved new chemical drug in China.

Following the recent acceptance of ICF004, ICF001 is another candidate from the Company’s high-barrier respiratory pipeline to reach this milestone, signaling an accelerated harvest phase for CF PHARMTECH, INC.’s innovative R&D. ICF001 utilizes a prodrug-based mechanism designed to achieve long-acting efficacy. As drugs in this class have already demonstrated blockbuster potential in treating rare and serious pulmonary diseases, ICF001 is positioned to capture significant growth as it expands into new indications.

Addressing Unmet Clinical Needs and Filling a Domestic Treatment Gap

ICF001 targets two critical categories of pulmonary hypertension: WHO Group 1 pulmonary arterial hypertension (PAH) and WHO Group 3 pulmonary hypertension associated with interstitial lung disease (PH-ILD). Both conditions are associated with poor prognosis and urgently require better treatment options.

  • PAH: As a rare and progressive disease, PAH continues to carry a heavy disease burden. Even with current standard therapies, the 5-year survival rate remains only around 50%–60%, and median survival is approximately 4–7 years.
  • PH-ILD: Prognosis is even more severe. Pulmonary vascular remodeling caused by interstitial lung disease results in a median survival of only 1.5–3 years, with a 3-year survival rate as low as 25%–40%, making PH-ILD a particularly challenging condition in the pulmonary hypertension field.

Notably, there are currently no approved targeted therapies for PH-ILD in China. The rapid development of ICF001 positions it to potentially become the first inhaled therapy approved for this indication in China, addressing a critical therapeutic void and offering a transformative treatment option for patients worldwide.

Tackling Key Industry Challenges with a Globally Differentiated Improved Mechanism

While the industry is shifting toward long-acting therapies to reduce dosing frequency, existing approaches often face challenges, including single-dose burden, local tolerability, and titration complexity, all of which can affect dose escalation and long-term patient adherence.

ICF001 is designed to address these clinical pain points through precise formulation and pharmacokinetic optimization, with the goal of delivering two key breakthroughs while demonstrating multi-indication expansion potential:

Enhanced patient adherence through reduced dosing frequency

By optimizing molecular structure and formulation, ICF001 increases drug loading efficiency and improves local tolerability, reducing the overall administration burden for long-term therapy.

Optimized pharmacokinetics through a “peak-shaving and trough-filling” profile, balancing safety and efficacy

Delivered directly to the lungs, ICF001 is designed to blunt peak plasma concentration (Cmax) while extending drug exposure (AUC). This “peak-shaving and trough-filling” profile improves systemic tolerability and may enhance clinical efficacy while maintaining safety.

“One drug, Multiple indications” Strategy

Expanding beyond PAH and PH-ILD, ICF001 utilizes a mechanism of action that targets pulmonary fibroblast activation, offering dual potential in pulmonary hypertension and pulmonary fibrosis. Backed by cutting-edge global research and clinical exploration of this drug class, ICF001 is expected to emerge as a next-generation blockbuster, addressing significant unmet needs in the broader respiratory market.

These differentiated advantages represent the Company’s R&D goals and strategic direction based on translational medicine models. If improvements in tolerability and titration efficiency are confirmed in subsequent clinical studies, ICF001 is expected to improve long-term treatment adherence, strengthen efficacy potential, and further expand clinical accessibility.

The rapid acceptance of this IND application marks another critical milestone in the Company’s clinical development of its high-barrier respiratory pipeline. It demonstrates the Company’s solid fundamentals, forward-looking strategic positioning, and efficient execution in innovative drug R&D. Furthermore, it established a strong foundation for the Company to further penetrate the global high-value inhalation therapy market to address unmet clinical needs. The market holds high expectations for the clinical application of such improved new drugs.

Validating Platform Value: Extending from Complex Formulation Capabilities to Innovative Drug Translation

The IND acceptance of ICF001 marks a key transition for CF PHARMTECH, INC.’s inhaled innovative drug program enters the regulatory phase. This progress represents a strategic breakthrough with long-term sustainable development potential:

Strategic Dimension

Implication

Validation of platform translation capability

The Company has integrated complex formulations, delivery systems, device engineering, and unmet clinical needs, demonstrating its capability to advance innovative drug programs.

Replicable R&D model

This progress establishes a proven methodology and a replicable R&D model for future innovation in respiratory and other therapeutic fields.

Value Driver Evolution

Supports a higher-level valuation based on the intersection of precision delivery technology, device engineering, and innovative clinical assets.

 

By leveraging its integrated global capabilities, CF PHARMTECH is building a multi-layered product portfolio centered on the synergy of advanced complex formulations and innovative therapeutics. This strategic focus solidifies the Company’s position in the high-value global inhalation market while enabling the expansion of its proprietary delivery technology into broader therapeutic areas and innovative drug development.

16/03/2026 Dissemination of a Financial Press Release, transmitted by EQS News.
The issuer is solely responsible for the content of this announcement.

Media archive at www.todayir.com

Chia Tai Enterprises International Proposes Name Change to CPBIO Biotech is the Core Growth Engine: Innovation Fuels Diversified Portfolio

EQS Newswire / 16/03/2026 / 19:20 UTC+8

Chia Tai Enterprises International Proposes Name Change to CPBIO

Biotech is the Core Growth Engine: Innovation Fuels Diversified Portfolio

 

(16 March 2026 – Hong Kong) Chia Tai Enterprises International Limited (Stock Code: 03839.HK) is pleased to announce today that it proposes to change its name to “CPBIO Holding Company Limited” (hereinafter referred to as “CPBIO” or the “Company”). The proposed name change aims to accurately reflect the Company’s current principal business and future strategic direction, further reinforcing its vision of becoming a worldleading biotechnology company. Under the new name “CPBIO”, the Company will continue to collaborate with global partners to advance the sustainable development of the biotechnology industry. The proposed change of company name is subject to approval by the shareholders at the general meeting and by the Registrar of Companies in Bermuda.

 

Business Focus: Biotech Contributes All Revenue, Continue to be the Core Growth Engine

This renaming marks a significant milestone in the Company’s history, accurately reflecting that the biotech business (including animal health products and chlortetracycline) now contributes all revenue. As the Company continues to focus and deepen its business operations, future efforts will be concentrated on fields such as synthetic biology and biological products. The new name, “CPBIO”, provides a more intuitive representation of the Company’s core direction – driving future growth through biotechnology and underscores its firm commitment to safeguarding life and health while promoting sustainable industry practices.

 

Core Strategy: Research, Innovation & Globalization to Capture Livestock Industry Upgrade & Biosecurity Trends

Positioned at the forefront of life sciences, CPBIO has successfully transitioned from a premier supplier of animal health products to a global provider of biotechnology solutions. As the global livestock industry accelerates toward large-scale, intensive operations and enhanced biosecurity, market demand for efficient and safe animal health products continues to rise. Leveraging this opportunity, the Company will consistently strengthen product R&D and technical innovation. While expanding its presence in the international market, CPBIO will deepen cooperation with global industry partners to build a robust business foundation based on solid biotechnological capabilities.

 

Corporate Mission: Championing Leadership as a WorldLeading Biotech Firm

As CPBIO embarks on this new chapter, it remains dedicated to upholding and promoting its deeply rooted corporate spirit. The Company consistently adheres to its grand vision of “Becoming a World-class Biotechnology Company” and employs it to steer the high-quality development of every aspect of the business. Under this vision, CPBIO is committed to its corporate mission: With innovative biotechnology, advance animal health, protect the earth, and benefiting mankind. This original aspiration is not only the cornerstone of past success but also the core driving force for future biotech innovation and application.

 

Future Outlook: Innovative and Synthetic Biologics + AI Powers ThroughCycle Growth Engine

CPBIO will activate a new core growth engine: Building on a strengthened life sciences foundation, enhanced global resource synergies, and expanded market networks, the Company will aggressively advance cutting-edge biologics innovation and strategically target the high-growth pet health sector.

At the same time, it will leverage advanced synthetic biology across its value chain while building an AI- and data-driven intelligent ecosystem. These engines will work synergistically to create a diversified biotech portfolio with strong through-cycle resilience, delivering comprehensive industry solutions and creating sustainable, long-term value for shareholders, customers, and partners.

– END –

 

 

About Chia Tai Enterprises International Limited

Listed on the Main Board of the Hong Kong Stock Exchange in July 2015, Chia Tai Enterprises International Limited (“CTEI”) (Stock Code: 03839.HK) is engaged in biotech business and investment business. We have established a strong presence and leadership position in the biotech industry in China.

 

CTEI is a subsidiary of Charoen Pokphand Foods Public Company Limited (Stock Code: CPF.TB, hereinafter referred as “CPF”). CPF is one of the world’s leading agri-food companies and is listed on the Stock Exchange of Thailand.

 

 

This press release is issued by DLK Advisory Limited on behalf of Chia Tai Enterprises International Limited.

 

For enquiries, please contact,

DLK Advisory 金通策略

pr@dlkadvisory.com

Tel: +852 2857 7101

Fax: +852 2857 7103

 

16/03/2026 Dissemination of a Financial Press Release, transmitted by EQS News.
The issuer is solely responsible for the content of this announcement.

Media archive at www.todayir.com

BIO-Europe Spring® 2026: Partnering Momentum Builds as Global Biopharma Leaders Set Course for Lisbon

EBD Group

/ Key word(s): Conference

BIO-Europe Spring® 2026: Partnering Momentum Builds as Global Biopharma Leaders Set Course for Lisbon

16.03.2026 / 11:00 CET/CEST

The issuer is solely responsible for the content of this announcement.


 

PRESS RELEASE

BIO-Europe Spring® 2026: Partnering Momentum Builds as Global Biopharma Leaders Set Course for Lisbon

MUNICH, GERMANY – March 16, 2026. The global biopharmaceutical community is preparing to gather in Lisbon, Portugal, for the 20th edition of BIO-Europe Spring®, the premier springtime partnering conference for the industry, taking place March 23–25, 2026.

More than 3,700 attendees from over 2,000 companies, including leading pharmaceutical firms, innovative biotech companies, and global investors, are expected along Lisbon’s shores for one of Europe’s most important meeting points for life science innovation and dealmaking. Held alongside LSX Europe as part of Life Sciences Spring Innovation Week, this year’s event will create an expanded platform for strategic discussions across biotech, pharma, and investment communities.

Partnering has opened and is now in full swing, with over 20,000 one-to-one meetings expected, reinforcing BIO-Europe Spring’s role as a vital hub for investment, collaboration, and cross-border engagement across the global life sciences ecosystem.

“Portugal’s life sciences sector has developed into a dynamic and internationally connected ecosystem, driven by strong research, innovative biotech companies, and growing investment activity,” said Joana Branco, Director of Innovation and Ecosystem at Biocant Park, co-host sponsor of BIO-Europe Spring 2026. Filipa Sacadura, Director General of P-Bio, also co-host sponsor, added: “Hosting BIO-Europe Spring 2026 in Lisbon is a fantastic opportunity to showcase Portugal’s innovation landscape and connect our biotech community with global industry leaders, investors, and partners.”

“We are excited to bring the 20th annual edition of BIO-Europe Spring to Lisbon, a city whose life sciences ecosystem continues to gain international recognition,” said Claire Macht, Director of BIO-Europe Spring. “With strong participation from biotech innovators, pharmaceutical leaders, and global investors, BIO-Europe Spring 2026 will provide an essential platform to explore new partnering opportunities and help shape the next wave of life science innovation.”

BIO-Europe Spring 2026 will focus on partnering and dealmaking from early-stage innovators to mature biotech companies. The event recently strengthened its collaboration with YVC Collective, a network of more than 600 emerging life sciences venture capital professionals across Europe. Through this partnership, YVC Collective members help review applications for the conference’s Startup Spotlight and Presenting Company programs, ensuring promising early-stage companies gain exposure to investors and industry leaders at a pivotal stage of development.

Key Sessions and Events at BIO-Europe Spring 2026:

The 20th annual BIO-Europe Spring conference will feature an engaging program curated by EBD Group (an Informa company) offering company presentations, panel discussions, and networking opportunities designed to foster collaboration across the life sciences value chain.

A featured panel, “Piecing Together the Therapeutic Landscape with Analyst Insights”, will leverage leading analyst intelligence and data-driven insights to provide a deep dive into the evolving biopharma ecosystem. Moderated by Daniel Chancellor (Evaluate), the panelists Samuel Bennett (Novo Nordisk), Hakan Goker (M Ventures), Laura Lane (Eli Lilly and Company), Toby Richardson (Johnson & Johnson), and Jan Van den Bossche (Andera Partners) will explore emerging trends, market dynamics, and investment opportunities across key therapeutic areas, offering strategic insights to navigate 2026 and beyond.

Another ever-popular, recurring session, “Day in the Life of an Experienced Dealmaker”, will offer a firsthand look at the current state of the life sciences landscape. Anton Gueth (EVOLUTION Life Science Partners), Evonne Sepsis (ESC Advisors), Claudio Costa-Neto (Jeito Capital), Evan Lippman (Teva Pharmaceuticals), and Chris Sheldon (GSK) will share strategies for navigating the complex biotech and pharma ecosystem.

The program will also spotlight emerging innovators through the Startup Spotlight, a live pitch competition showcasing promising biotech startups. Selected companies will present their innovations to the BIO-Europe Spring audience and a panel of expert judges, offering insight into the next generation of life science innovation.

Partnering and Registration for BIO-Europe Spring 2026

One-to-one meetings will be powered by partneringONE®, an industry-standard platform that enables delegates to search, request, schedule, and conduct meetings efficiently. To enhance access and extend engagement beyond the in-person event, the conference will continue with two days of virtual partnering on March 31–April 1, allowing participants to connect regardless of time zone or travel constraints.

Registration information for BIO-Europe Spring is available online. Discounted rates are still available until March 20, 2026.

Additional Links and Information

BIO-Europe Spring is organized by EBD Group, an Informa company.

For more information and live updates, please visit the conference website at: https://informaconnect.com/bioeurope-spring and follow BIO-Europe Spring 2026 on LinkedIn.

About Informa and EBD Group

EBD Group’s mission is to help collaborations get started across the life science value chain. Our range of partnering conferences has grown to become the largest and most productive conference portfolio in the industry. Each one of our landmark events, held in key life science markets around the world, is powered by our state-of-the-art partnering software, partneringONE, that enables delegates to efficiently identify and engage with new opportunities via one-to-one meetings. Today, our events and those of our sister organization, LSX (BIO-Europe, BIO-Europe Spring®, LSX Europe, Biotech Showcase™, LSX USA, Investival Showcase USA, ChinaBio® Partnering Forum, Asia Bio Partnering Forum, LSX Nordic, BioEquity Europe, Investival Showcase EU, and the European Lifestars Awards), annually attract more than 15,000 senior life science executives who engage in over 50,000 one-to-one partnering meetings. These vital one-to-one engagements are the wellspring of deals that drive innovation in our industry.

EBD is an Informa company. Informa is a leading international Live B2B Events, B2B Digital Services, and Academic Markets Group. Informa is a member of the FTSE 100 and works in over 30 countries.

For more information, please visit: https://informaconnect.com/partnering-investment-strategy/

Media Contacts:

MC Services AG
+49 89 2102280
contact@mc-services.eu

Informa
Paul Gilbertson
paul.gilbertson@informa.com


16.03.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
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2291418  16.03.2026 CET/CEST

NVision and Aarhus University Awarded Innovation Fund Denmark Grant to Advance Clinical Translation of Quantum-Enhanced MRI

NVision Imaging Technologies GmbH

/ Key word(s): Miscellaneous

NVision and Aarhus University Awarded Innovation Fund Denmark Grant to Advance Clinical Translation of Quantum-Enhanced MRI

16.03.2026 / 10:15 CET/CEST

The issuer is solely responsible for the content of this announcement.


NVision and Aarhus University Awarded Innovation Fund Denmark Grant to Advance Clinical Translation of Quantum-Enhanced MRI

The €5.4 million (40m DKK) investment for the MIRAQLE project supports the development of scalable, clinically deployable hyperpolarized MRI for early liver cancer diagnostics.
 

ULM, Germany & AARHUS, Denmark — March 16, 2026 — NVision, a quantum technology company, and Aarhus University have secured a €5.4 million (40m DKK) grant for the MIRAQLE project under Denmark’s Grand Solutions in Quantum Technologies program. The award is a significant endorsement of NVision’s quantum hyperpolarization technology and establishes a direct route for quantum-enabled diagnostics to move from the lab to the clinic.

Cancer is often detected too late. Although standard MRI scans are good at showing a tumor’s size and location, they miss the metabolic activity that reveals how aggressive the disease is or whether a treatment is working.

MIRAQLE aims to change this. Researchers from the MR Research Centre at Aarhus University and NVision Imaging Technologies will develop a new type of MRI platform capable of visualizing cancer metabolism. By boosting the imaging agent’s MRI signal, metabolic activity can become visible during a routine MRI scan. This could make it possible to detect serious disease earlier and to monitor treatment effects far more precisely than is currently possible.

Expanding Clinical Applications to Liver Cancer

NVision’s research partnerships are rapidly expanding to cover a diverse range of medical applications. While research at Memorial Sloan Kettering Cancer Center is focused on monitoring treatment efficacy in various cancers, NVision’s recently established research hub at the University of Cambridge Department of Radiology allows for the exploration of both oncology and non-oncology applications, including general liver disease and multiple sclerosis.

The new research project at Aarhus University builds on this momentum with a dedicated focus on liver cancer. In hepatocellular carcinoma, it can be difficult for doctors to distinguish between benign changes and early-stage liver cancer, often delaying diagnosis until the disease is advanced. With NVision’s technology, doctors will be able to not only detect the disease earlier but also assess how aggressive it is.

“Our expanding network of research partnerships enables us to advance the use of hyperpolarized MRI across a broad spectrum of critical medical applications—from early disease detection and stratification to monitoring oncology treatments and tailoring therapies based on metabolic response,” said Prof. Myriam Chaumeil, Head of Research and MIRAQLE project lead at NVision. “Liver cancer is a compelling application because hyperpolarized MRI can reveal the metabolic activity that drives tumor growth in real time, providing insights that conventional imaging cannot offer.”

“We will be able to see how the cancer behaves, not just where it is. This could change the feedback cycle from months to days, making a decisive difference to when and how patients are treated,” said Professor Christoffer Laustsen, project leader and Head of the MR Research Centre at Aarhus University.

Up to 100,000 Times More Sensitive

NVision’s proprietary technology, POLARIS, is based on quantum physics and can make MRI scans up to 100,000 times more sensitive than those available today. This means that even very small changes on the cellular level can be detected. At the same time, the scan is carried out entirely without radioactive radiation – unlike many current methods used in cancer diagnostics. POLARIS is being developed so that it can be used in regular hospitals and integrated into existing MRI infrastructure.

Driving this clinical translation is the goal of the MIRAQLE project, which spans everything from laboratory research to preclinical and clinical studies in hepatocellular carcinoma to demonstrate the technology’s diagnostic value.

Strong European Backing

MIRAQLE strengthens NVision’s robust portfolio of publicly funded European research consortiums. The project joins a growing list of successful initiatives aimed at advancing and commercializing quantum medical technology, including CHARM, HYPERCELL, MAGSENSE, Q-AID, Que-MRT, and most recently, the AURORA project. Together, these consortiums represent more than €35 million in public grant funding secured since 2022 to support the transition of NVision’s technology from the lab to the clinic.

About NVision Imaging

NVision Imaging was founded in 2015 and is headquartered in Ulm, Germany. By leveraging advances in quantum physics, NVision enables real-time visualization of metabolism on standard MRI, aiming to set a new standard for faster drug development, earlier diagnosis, and better therapy decisions. Learn more at nvision-imaging.com.

Contact:

Leah Wiedenmann
NVision
leah.wiedenmann@nvision-imaging.com


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2291810  16.03.2026 CET/CEST

BioVersys Receives Green Light from US FDA for BV100 HABP/VABP Phase 3 Pivotal Trial Start

 

Basel, Switzerland. March 16, 2026, 7am CET

 

 

  • BV100 is a potential best-in-class anti-infective agent in treating hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP), caused by carbapenem-resistant Acinetobacter baumannii (CRAB).
  • US FDA confirms that the BV100 global pivotal Phase 3 HABP/VABP trial may proceed, based on the initial IND submission.
  • BV100 global pivotal Phase 3 is on track to read-out by the end of 2027.

 

BioVersys AG (SIX: BIOV), a multi-asset, clinical stage biopharmaceutical company focusing on research and development of novel antibacterial products for serious life-threatening infections caused by multi-drug resistant (MDR) bacteria, announced today that the US Food and Drug Administration (US FDA) has confirmed that the global Phase 3 pivotal trial to recruit US patients into the RIV-TARGET clinical trial (NCT07326540) can proceed. The Phase 3 trial will recruit patients with hospital-acquired or ventilator-associated bacterial pneumonia (HABP or VABP), due to carbapenem-resistant Acinetobacter baumannii-calcoaceticus Complex (CRABC).

CRABC is a highly-drug resistant Gram-negative pathogen that is recognized as a critical priority by global health authorities. BV100 is a novel intravenous formulation of rifabutin based on the newly identified mode of action for the active uptake of rifabutin into the Acinetobacter baumannii-calcoaceticus complex.  BV100 is being developed for MDR hospital infections caused by Acinetobacter baumannii, including carbapenem-resistant Acinetobacter baumannii (CRAB) strains. BV100 has Qualified Infectious Disease Product (QIDP) Designation from the U.S. FDA, making BV100 eligible for priority FDA review, Fast Track designation, and a five-year extension of market exclusivity.

Dr. Glenn E Dale, Chief Development Officer: “This is a significant step towards our goal of completing the BV100 global Phase 3 trial by the end of 2027. HABP and VABP infections remain a leading cause of infectious disease hospital mortality and represent a substantial burden on healthcare systems. Our teams have already gathered interest from US-based clinical sites to participate in the trial, and this successful IND application will allow us to activate the clinical sites prior to enrolling US patients in the coming months.”

Dr. Marc Gitzinger, Chief Executive Officer of BioVersys: “We are excited about this regulatory development. Enrolling US patients into the trial is an important contribution towards the global nature of the study. This follows closely behind our announcement in December 2025 that we had initiated the BV100 global Phase 3 trial. I am incredibly proud of our team’s multi-pronged efforts in ensuring that this trial can proceed simultaneously in all the key regions of the world. We will bring this much-needed treatment option to patients in dire need.”

Phase 3 trial design

The global Phase 3 trial, is a randomized, active-controlled two-part parallel-group trial to evaluate the efficacy and safety of BV100 plus low-dose polymyxin B in patients with HABP or VABP suspected or confirmed to be due to CRABC infection (RIV-TARGET). Part A is the pivotal, randomized, comparative portion of the trial, employing a partially blinded design aiming to enroll approximately 300 HABP/VABP patients with suspected or confirmed CRABC infections. Patients will be randomized 1:1 to receive either [1] BV100 combined with low dose polymyxin B or [2] colistin combined with high-dose ampicillin-sulbactam, with both arms allowing meropenem as background in case of polymicrobial infections. The primary efficacy endpoint is defined as 28-day all-cause mortality (ACM) in the CRABC microbiological modified intention-to-treat (CRABC m-MITT) population. Secondary efficacy endpoints will include clinical cure status at the test of cure (ToC) in CRABC m-MITT, ventilator free days, time spent in intensive care unit (ICU) and time in hospital. As part of the study protocol, data safety monitoring boards (DSMB)[1] will be convened at regular intervals to review trial progress.

The Phase 3 trial also includes an open-label, non-randomized, additional single group (Part B) to evaluate the efficacy and safety of BV100 plus low-dose polymyxin B in patients with HABP or VABP due to CRABC known to be resistant to colistin or polymyxin B prior to study entry and patients where colistin or polymyxin B regimen has failed prior to study entry. Approximately 25 patients are expected to be enrolled in Part B.

This pivotal Phase 3 trial follows the successful completion of a Phase 2 trial in documented Acinetobacter VABP patients. BV100 combined with polymyxin B demonstrated a clear survival benefit, resulting in a 50% relative reduction in 28-day ACM compared with best available therapy (BAT), in VABP patients suffering from confirmed CRAB infections (28-day ACM: 60% for BAT vs 25% for BV100), and was generally safe and well tolerated. The current Phase 3 trial mimics the successful study design of the positive Phase 2 trial and is expected to read-out towards the end of 2027. Subsequent regulatory submissions aimed at commercial approval are planned in 2028, initially for the US, Europe and China.

In parallel to the Phase 3 pivotal trial an open-label Phase 2b differentiation trial (RIV-CARE) will be initiated in H1 2026 comparing BV100 with BAT in multiple geographies. The Phase 2b trial aims to provide real world evidence of clinical practices in settings with very high drug resistance levels. Interim analysis is planned for end of 2026.

About BV100

BV100 is a novel formulation of rifabutin suitable for intravenous administration, with a recently discovered novel mode of action showing an active uptake of rifabutin into the Gram-negative bacterial species, Acinetobacter baumannii. For the first time, BV100 allows for the targeting of the RNA-polymerase enzyme in Gram-negative bacteria with a human-suitable dose. BV100 is being developed for the treatment of infections caused by Acinetobacter baumannii calcoaceticus complex (ABC), including carbapenem-resistant ABC (CRABC) in critically important indications of ventilator associated bacterial pneumonia (VABP), hospital-acquired bacterial pneumonia (HABP) and bloodstream infections (BSI). BV100 was granted QIDP Designation by the U.S. FDA in May 2019 for use in the treatment of VABP, HABP and BSI, making BV100 eligible for priority FDA review, Fast Track designation, and a five-year extension of market exclusivity upon approval of the first QIDP indication.

 

About Acinetobacter baumannii

Acinetobacter baumannii calcoaceticus complex (ABC) are Gram-negative bacteria found in the environment (e.g., in soil and water) and an opportunistic pathogen in humans, typically infecting critically ill and immunocompromised patients, that can result in severe pneumonia and bloodstream infections in addition to affecting other parts of the body. ABC is considered a significant worldwide threat in the healthcare setting given its ability to survive for prolonged periods on surfaces, combined with its ability to develop or acquire resistance to standard of care antibiotics, e.g. carbapenems. Carbapenem-resistance as well as multi-drug resistance (MDR) rates for ABC are among the highest recorded for any bacteria in current times (The Lancet 2022; 399: 629–55). Incidence and resistance rates for ABC are trending upwards and COVID-19 has exacerbated this significantly. BioVersys forecasts the annual number of carbapenem-resistant A. baumannii infections in hospitals to have surpassed one million globally and due to the limited treatment options, such infections come with high (up to 50%) mortality rates.

 

About BioVersys

BioVersys AG is a multi-asset, clinical stage biopharmaceutical company focused on identifying, developing and commercializing novel antibacterial products for serious life-threatening infections caused by multi-drug resistant (“MDR”) bacteria. Derived from the company’s two internal technology platforms (TRIC and Ansamycin Chemistry), candidates are designed and developed to overcome resistance mechanisms, block virulence production and directly affect the pathogenesis of harmful bacteria towards the identification of new treatment options in the antimicrobial and microbiome fields. This enables BioVersys to address the high unmet medical need for new treatments against life-threatening resistant bacterial infections and bacteria-exacerbated chronic inflammatory microbiome disorders. The company’s most advanced research and development programs address nosocomial infections of Acinetobacter baumannii (BV100, Phase 3), and tuberculosis (alpibectir, Phase 2, in collaboration with GlaxoSmithKline (GSK) and a consortium of the University of Lille, France). BioVersys is located in the biotech hub of Basel, Switzerland.

BioVersys contact 
Hernan Levett, CFO, Tel. +41 61 633 22 50; Mail: hernan.levett@bioversys.com
For media: media@bioversys.com Website: www.bioversys.com

 

 

Disclaimer

This communication expressly or implicitly contains certain forward-looking statements, such as “believe”, “assume”, “expect”, “forecast”, “project”, “may”, “could”, “might”, “will” or similar expressions concerning BioVersys and its business, including with respect to the progress, timing and completion of research, development and clinical studies for product candidates. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of BioVersys to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. BioVersys is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise.

 


[1] The DSMB review is the periodic evaluation of unblinded or partially unblinded clinical trial data by an independent committee of experts to determine whether the study should continue, be modified, or be stopped based on safety, efficacy, or futility considerations.