EvoNext Holdings SA makes available the consolidated financial statements of Ascend Sport Technology AG for the financial year 2025/26

EvoNext Holdings SA / Key word(s): Merger

EvoNext Holdings SA makes available the consolidated financial statements of Ascend Sport Technology AG for the financial year 2025/26

05-Nov-2026 / 07:10 CET/CEST

Release of an ad hoc announcement pursuant to Art. 53 LR

The issuer is solely responsible for the content of this announcement.


This press release or the information contained therein is not being issued and may not be distributed in the United States of America, Canada, Australia or Japan or any other jurisdiction in which the distribution or release would be unlawful or require registration or any other measure and does not constitute an offer of securities for sale in any country.

PRESS RELEASE | AD HOC ANNOUNCEMENT PURSUANT TO ART. 53 LR

EvoNext Holdings SA makes available the consolidated financial statements of Ascend Sport Technology AG for the financial year 2025/26

Reinach / Lucerne, Switzerland, 5 November 2026 – As part of the transaction documentation ahead of the upcoming merger, today EvoNext Holdings SA is making available the unaudited consolidated financial statements of Ascend Sport Technology AG (“Ascend”) for the financial year ended 30 June 2026, together with comparative figures for the financial year ended 30 June 2025.

Ascend reports the following unaudited key figures1:

In CHF million FY 2025/26   FY 2024/25
Income Statement
Net revenues 43.8 37.3
EBITDA 25.0 18.9
Depreciation (3.5) (3.2)
Amortization (9.4) (8.1)
EBIT 12.0 7.5
Net profit 8.7 5.3
Balance Sheet
Cash and cash equivalents   30.1 26.8
Securities 3.0 3.9
Net working capital2 15.1 8.9
Financial liabilities3 2.6 4.0
Total equity 76.0 66.8

1 Net revenues, EBITDA, depreciation, amortization, EBIT and net profit relate to the financial years from 1 July to 30 June (FY 2025/26 and FY 2024/25); all balance sheet items are stated as at 30 June 2026 and 30 June 2025, respectively.
2 Net working capital comprises trade receivables, other current receivables, inventories and accrued income and prepaid expenses, less trade payables, other current liabilities, current provisions and deferred revenue and accrued expenses. It excludes cash and cash equivalents, securities, financial liabilities and non-current provisions.
3 Financial liabilities comprise current and non-current financial liabilities (FY 2025/26: CHF 2.6 million current, nil non-current; FY 2024/25: CHF 2.1 million current, CHF 1.9 million non-current).

All figures are unaudited.

The complete unaudited consolidated financial statements of Ascend for the financial year 2025/26 (without notes), comprising the consolidated balance sheet, income statement and cash flow statement, are available here.

EvoNext Holdings SA and Ascend Sport Technology AG signed the merger agreement on 1 November 2026. The Swiss sports technology holding company Ascend is expected to become, subject to certain conditions including the approval of the shareholders of both companies, a publicly listed entity through a merger into EvoNext with its existing listing on SIX Swiss Exchange.

Contact for investors and media

EvoNext Holdings SA

investors@evonextholdings.com

susanne.muehlemann@lemongrass.agency / +41 79 223 70 81

Disclaimer

This publication constitutes neither an offer to sell nor a solicitation to buy securities of EvoNext Holdings SA and it does not constitute a prospectus or a similar notice within the meaning of articles 35 et seqq. or 69 of the Swiss Financial Services Act. Any offer and listing of any securities in EvoNext Holdings SA (“Securities”) will be made solely by means of, and on the basis of, a prospectus which is to be published. An investment decision regarding any publicly offered Securities should only be made on the basis of such prospectus. The prospectus will be available free of charge from the accompanying bank.

This publication may contain specific forward-looking statements, e.g., statements including terms like “believe”, “assume”, “expect”, “forecast”, “project”, “may”, “could”, “might”, “will” or similar expressions. Such forward-looking statements are subject to known and unknown risks, uncertainties and other factors which may result in a substantial divergence between the actual results, financial situation, development or performance of EvoNext Holdings SA or Ascend Sport Technology AG and those explicitly or implicitly presumed in these statements. Against the background of these uncertainties, readers should not rely on forward-looking statements. EvoNext Holdings SA assumes no responsibility to update forward-looking statements or to adapt them to future events or developments. Moreover, financial information contained in this publication may be preliminary and unaudited.

This communication is being distributed only to, and is directed only at (i) persons outside the United Kingdom, (ii) persons who have professional experience in matters relating to investments falling within article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005 (the “Order”) or (iii) high net worth entities, and other persons to whom it may otherwise lawfully be communicated, falling within Article 49(2) of the Order (all such persons together being referred to as “Relevant Persons”). Any potential investment or investment activity to which this communication relates will be available only to Relevant Persons and will be engaged in only with Relevant Persons. Any person who is not a Relevant Person must not act or rely on this communication or any of its contents.

This communication does not constitute an “offer of securities to the public” within the meaning of Regulation 2017/1129 of the European Union (the “Prospectus Regulation”) of the securities referred to in it (the “Securities”) in any member state of the European Economic Area (the “EEA”) or, in the United Kingdom (“UK”), the UK Public Offers and Admissions to Trading Regulations 2024 (the “POATRs”). Any placements of any Securities to persons in the EEA or the UK will be made pursuant to an exemption under the Prospectus Regulation or the POATRs (as applicable), as implemented in member states of the EEA or the UK, from the requirement to produce a prospectus for offers of Securities.

Any securities referred to herein have not been and will not be registered under the US Securities Act of 1933, as amended (the “Securities Act”), and may not be offered or sold in the United States or to US persons (as such term is defined in Regulation S under the Securities Act) unless the securities are registered under the Securities Act, or an exemption from the registration requirements of the Securities Act is available. The issuer of the securities has not registered, and does not intend to register, any portion of any potential placements in the United States, and does not intend to conduct a public offer of securities in the United States.

This communication is not for distribution in the United States, Canada, Australia, Japan or any other jurisdiction into which the same would be unlawful and does not constitute an offer of securities for sale in such countries. This communication does not constitute an offer to sell, or the solicitation of an offer to buy, securities in any jurisdiction in which is unlawful to do so.

Additional features:

File: 2026_11_05_EvoNext Ad hoc PRESS RELEASE_Ascend Sport Technology consolidated financial statements FY 25_26


End of Inside Information


Language: English
Company: EvoNext Holdings SA
Angensteinerstrasse 6
4153 Reinach
Switzerland
Phone: +41 61 485 20 00
E-mail: investors@evonextholdings.com
Internet: www.evonextholdings.com
ISIN: CH1262055788
Valor: 126205578
Listed: SIX Swiss Exchange
EQS News ID: 2428734

 
End of Announcement EQS News Service

2428734  05-Nov-2026 CET/CEST

Evotec Reports Third Quarter and Nine-Month 2026 Results: Building Growth Momentum Toward 2030 Goals

Evotec SE

/ Key word(s): 9 Month figures/Quarterly / Interim Statement

Evotec Reports Third Quarter and Nine-Month 2026 Results: Building Growth Momentum Toward 2030 Goals

05.11.2026 / 07:30 CET/CEST

The issuer is solely responsible for the content of this announcement.


Evotec Reports Third Quarter and Nine-Month 2026 Results: Building Growth Momentum Toward 2030 Goals
 

  • Financial performance: Q3 and nine-month Group revenue of €164.9 m and €465.0 m, respectively (Q3: €164.2 m, 9M: €477.4 m at CER); adj. Group EBITDA of -€1.6 m and -€44.3 m, respectively (Q3: -€1.7 m, 9M: -€39.1 m at CER)
  • Robust commercial momentum: Net sales* in D&PD base business increased 24% vs. 9M 2025 accompanied by continued positive development across key commercial indicators.
  • FY 2026 guidance reaffirmed: Expected Group revenue of €570 to €610 m (€595 to €635 m CER) and adj. Group EBITDA of -€105 to -€70 m (-€90 to -€60 m CER).
  • 2030 framework further detailed: Around €1 billion in Group revenue by 2030 with further upside potential; adjusted EBITDA margin of 20% at YE 2028 and above 20% at YE 2030.
  • Continued progress across differentiated platforms: Evotec confirms selection by Vertex Pharmaceuticals for commercial manufacturing of povetacicept; advancement of orthopoxvirus antibody program into Phase 1 in collaboration with DoW; new collaborations with Plectonic and Odyssey Therapeutics broaden partnered innovation activities.
  • Horizon transformation ahead of plan: More than 20% of €75 million annual run-rate savings target delivered by September, already within 20-30% contribution planned for full-year 2026; workforce and footprint measures on track.
  • Leadership Update: Dr. Joanna Holbrook appointed Chief Scientific Officer, strengthening Evotec’s focus on scientific excellence, platform differentiation and partnered innovation.
  • Investor and analyst webcast and conference call today: 2 p.m. CET / 1 p.m. GMT / 8 a.m. EST; registration and webcast details below.

Hamburg, Germany, November 5, 2026 – Evotec SE (NASDAQ: EVO; Frankfurt Prime Standard: EVT) today announced financial results for the third quarter and first nine months of 2026, provided an update on the implementation of its Horizon transformation and outlined its strategic and financial ambition for 2030.

Dr. Christian Wojczewski, Chief Executive Officer of Evotec, said:

“During the third quarter and first nine months of 2026, we made encouraging progress across several areas that are important to Evotec’s future development. Commercial momentum remained solid, Horizon is delivering ahead of plan and Just – Evotec Biologics is advancing toward commercial-scale manufacturing. Implementation of our strategy is gaining momentum and is increasingly reflected in our performance. Group revenue reached €164.9 million in the third quarter, well above the first two quarters of the year, supported by a robust contribution from the D&PD base business.

We also successfully launched several new partnerships based on our technology platforms. Recent examples include Plectonic, where we are exploring new T-cell-engaging approaches in solid tumors. With Odyssey Therapeutics, our AI-enabled discovery platform is supporting drug discovery in autoimmune and inflammatory diseases. These collaborations illustrate how we are applying our differentiated scientific capabilities in new areas, creating exciting opportunities with partners.”

Selected Business Highlights

Evotec made strong progress across its differentiated platforms and strategic partnerships:

Just – Evotec Biologics (JEB)

  • Vertex Pharmaceuticals – Commercial Manufacturing of Povetacicept: Evotec confirms that Just – Evotec Biologics has been selected by Vertex Pharmaceuticals for commercial manufacturing of povetacicept at its J.POD® Redmond facility. The agreement marks an important step in the evolution of JEB’s continuous manufacturing platform toward commercial readiness. Evotec is highly confident in its ability to fulfill its commercial manufacturing and supply commitments to Vertex.
  • DoW Orthopoxvirus Program – JST-018 Phase 1 Initiated: In September 2026, Evotec announced the initiation of a Phase 1 clinical trial evaluating JST-018, an investigational antibody cocktail developed by Just – Evotec Biologics under the U.S. Department of War’s Accelerated Antibodies Program. Just – Evotec Biologics advanced the program from antibody sequence selection through preclinical development, process development, regulatory submission and cGMP manufacture of clinical trial materials.

Discovery and Preclinical Development (D&PD)

  • Jazz Pharmaceuticals – Phase 1 Initiated: Jazz Pharmaceuticals has initiated a Phase 1 clinical trial of a candidate for the potential treatment of narcolepsy and idiopathic hypersomnia. The candidate was discovered through Jazz’s sleep disorders collaboration with Evotec. Evotec combined its proprietary virtual screening and generative AI platforms with rational design to identify novel leads, subsequently optimized with the aid of cryoEM and molecular dynamics simulations. Evotec is eligible to milestone payments.
  • Plectonic Research Collaboration – Novel Immunotherapy Approaches: In September 2026, Evotec and Plectonic entered a research collaboration combining Evotec’s BiTco platform with Plectonic’s LOGIBODY® technology to explore new T-cell-engaging approaches for solid tumors. The collaboration will generate preclinical proof-of-concept data to evaluate whether the combined technologies can improve the precision and potency of these approaches.
  • Odyssey Therapeutics Research Collaboration – AI-Enabled Drug Discovery: In August 2026, Evotec entered an R&D collaboration combining Odyssey’s expertise in autoimmune and inflammatory diseases with Evotec’s AI-enabled discovery platform, advanced screening capabilities and proprietary compound libraries. Evotec is eligible to receive milestone payments based on the successful delivery of validated starting points for drug discovery across multiple targets.

Commercial Execution

Commercial momentum and execution continued to strengthen during the third quarter of 2026. Net sales in the D&PD base business, comprising stand alone services and integrated programs, increased by 24% year-on-year in the first nine months. Positive trends extended across the commercial funnel, with growth in the customer base, higher proposal activity and faster proposal turnaround. The strategic partnership opportunity pipeline also continued to expand.

Horizon Transformation

Horizon is progressing ahead of plan, with structural measures translating into measurable financial and operational improvements. By the end of September, Evotec had delivered more than 20% of the €75 million in annual run-rate savings targeted by the end of 2027, already within the 20-30% contribution planned for full-year 2026. Approximately half of the planned workforce reductions have been implemented. Footprint consolidation is advancing, with three of the four site closures expected to be completed by year-end and the fourth in the first quarter of 2027. Alongside these measures, Evotec is concentrating scientific capabilities in focused Centers of Excellence and strengthening commercial execution to build a more efficient operating model and support sustainable profitability. Evotec expects to deliver the transformation program in full and on schedule by the end of 2027.

Leadership Update

Chief Scientific Officer: Dr. Joanna Holbrook

As announced on October 15, 2026, Dr. Joanna Holbrook has succeeded Dr. Cord Dohrmann as Chief Scientific Officer and member of Evotec’s Management Board, effective November 1, 2026.

Bringing more than 25 years of experience as a scientist and R&D leader, Dr. Holbrook will lead Evotec’s global scientific strategy, with a focus on strengthening scientific differentiation across discovery and development services, technology platforms and proprietary innovation. Her expertise across data, AI and novel technologies will support Evotec in building integrated solutions to important challenges in drug discovery and helping customers and partners discover and develop new medicines faster and with a greater probability of success.

2030 Mid-Range Framework – Building a Structurally Stronger Business

Evotec is building a more balanced and profitable business, drawing on the distinctive strengths of its component parts. The 2030 framework calls for around €1 billion in Group revenue by 2030, with potential for additional upside. It includes an adjusted EBITDA margin of 20% by the end of 2028, rising above 20% by the end of 2030.

The D&PD base business, comprising standalone services and integrated programs, is expected to contribute approximately 40% of Group revenue in 2030. Growth is expected to be supported by continued market recovery, commercial investments and Evotec’s differentiated service offerings.

D&PD strategic partnerships and innovation-related activities are expected to contribute approximately 20% at above-average margins. This contribution incorporates risk-adjusted assumptions regarding program progression and associated revenue, while future royalty income is not included. Performance exceeding these assumptions could provide additional revenue upside beyond the approximately €1 billion framework.

Just – Evotec Biologics is expected to contribute approximately 40% of Group revenue as the business scales, supported by capacity expansion, licensing income and future, contractually agreed royalties.

Profitability is expected to benefit from greater contribution from scalable, higher-margin activities, operating leverage and continued cost efficiency.

Financial Results

Claire Hinshelwood, Chief Financial Officer of Evotec, said:

“Our strong third-quarter performance reflects the positive impact of the commercial investments and Horizon initiatives launched earlier this year. We are now seeing these efforts translate into improved profitability and operational momentum. Looking ahead, our focus remains on converting this momentum into sustainable revenue growth and stronger cash generation, while maintaining disciplined cost management, liquidity oversight, and capital allocation. Today, we are pleased to provide greater transparency into our 2030 financial framework, including the business mix and operational drivers that support a high-quality, diversified platform for future earnings growth.”

Group Financials

For the third quarter of 2026, Group revenue amounted to €164.9 million (€164.2 million CER), essentially unchanged from €163.9 million in the prior-year quarter. Adjusted Group EBITDA was -€1.6 million (-€1.7 million CER), versus -€15.0 million in the same prior‑year period, reflecting a marked year-on-year improvement of 89.1% primarily attributable to lower cost of revenue.

For the nine months ended September 30, 2026, Group revenue amounted to €465.0 million (€477.4 million CER), compared with €535.1 million in the prior-year period, reflecting a 13.1% decline. Consistent with the Company’s focus on cost discipline, R&D expenses amounted to €29.7 million or 6.4% of total Group revenue, compared with €42.3 million or 7.9% of total Group revenue in the prior-year period. Adjusted Group EBITDA decreased to
-€44.3 million (-€39.1 million CER), down from -€16.9 million for the nine months ending September 30, 2025. The decrease in revenue was partially offset by lower cost of revenue.

Evotec closed the third quarter of 2026 with a liquidity position of €400.9 million, reflecting a net debt position.

Segment Financials (excluding intersegment revenue)

Discovery and Preclinical Development (D&PD)

For the third quarter of 2026, revenue for Discovery & Preclinical Development totaled €120.1 million (€119.6 million CER), representing a modest year-on-year decline of 2.3%. Adjusted EBITDA for the quarter improved to
-€1.0 million (-€1.4 million CER), compared with -€9.5 million in the third quarter of 2025.

For the first nine months of 2026, revenue totaled €348.0 million (€355.5 million CER), compared with
€391.9 million in the prior-year period. The 11.2% year-on-year decrease was primarily driven by lower sales-to-revenue conversion across all D&PD segments. Adjusted EBITDA for the segment was -€25.5 million
(-€19.8 million CER), compared with -€18.8 million in the prior-year period. The decrease was primarily driven by lower revenue and partially offset by a lower cost base across cost of revenue, R&D and SG&A.

Just – Evotec Biologics (JEB)

Third quarter 2026 revenue at Just – Evotec Biologics totaled €44.8 million (€44.6 million CER), representing a 9.4% increase compared with the prior-year period. Adjusted EBITDA reached -€0.6 million (-€0.3 million CER), compared with -€5.5 million in the prior-year period.

For the first nine months of 2026, revenue totaled €117.1 million (€121.9 million CER), compared with
€143.2 million in the same period in 2025. The 18.3% year-on-year decrease was primarily driven by the $25 million Sandoz license sale recognized in Q1 2025 and delayed program activities. Adjusted EBITDA amounted to
-€18.8 million (-€19.3 million CER), compared with an Adjusted EBITDA of €1.9 million in the prior-year period.

Reaffirming Full-Year 2026 Guidance

Evotec confirms its full-year 2026 outlook for Group revenue of approximately €570 to €610 million (€595 to
€635 million CER) and adjusted Group EBITDA of approximately -€105 to -€70 million (-€90 to -€60 million CER).

Strategic Review

The strategic evaluation announced in connection with the Company’s first quarter 2026 results on May 6, 2026, remains ongoing and continues alongside the implementation of the Horizon transformation program. Additional details regarding the review are available in the Company’s Q1 2026 results announcement.

 
Webcast Details

Evotec will host a webcast and conference call today at 2 p.m. CET / 1 p.m. GMT / 8 a.m. EST.

To join the audio webcast and to access the presentation slides, please register via this link.

The on-demand replay of the webcast will be available under the same link after the event and on our website.

Conference Call Details

To join the conference call, please pre-register via this link. You will receive a confirmation email with dedicated dial-in details such as telephone number, access code and PIN to access the call.
A simultaneous slide presentation for participants dialing in via phone is available under this link.

 
*Net Sales: includes signed work orders, positive change orders and negative change orders
 

About Evotec SE

Evotec is a life science company pioneering the future of drug discovery and development. By integrating breakthrough science with AI-driven innovation and advanced technologies, Evotec accelerates the journey from concept to cure with greater speed, intelligence and precision. The company’s expertise spans small molecules, biologics, cell therapies and associated modalities, supported by proprietary platforms including Molecular Patient Databases, PanOmics and induced pluripotent stem cell-based disease modeling. Through flexible partnering models tailored to customers’ needs, Evotec works with all Top 20 pharmaceutical companies, more than 800 biotechnology companies, academic institutions and other healthcare stakeholders. Evotec’s offerings range from standalone services to fully integrated research and development programs and long-term strategic partnerships, combining scientific excellence with operational agility. Through Just – Evotec Biologics, the company is redefining biologics development and manufacturing to improve accessibility and affordability. With a portfolio of more than 100 proprietary research and development assets, most of which are co-owned, Evotec focuses on key therapeutic areas including oncology, cardiovascular and metabolic diseases, neurology and immunology. Evotec’s global team of around 4,500 experts operates from sites in Europe and the United States, providing complementary technologies and services through a network of synergistic centers of excellence. Learn more at www.evotec.com and follow Evotec on LinkedIn and X at @Evotec.

 

Forward-Looking Statements

This announcement contains forward-looking statements concerning future events, including Evotec’s financial results, full-year 2026 outlook, expected commercial conversion, anticipated strategic partnership and milestone contributions, Horizon implementation, expected cost savings, liquidity, financial flexibility and future business performance. Words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “potential,” “should,” “target,” “would” and variations of these words and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based on information available to Evotec and on expectations and assumptions considered reasonable by the company at the time the statements were made. No assurance can be given that these expectations will prove correct. Forward-looking statements involve known and unknown risks and are based on assumptions and estimates that are inherently subject to significant uncertainties and contingencies, many of which are beyond Evotec’s control. Evotec expressly disclaims any obligation or undertaking to publicly update or revise any forward-looking statements contained in this announcement to reflect changes in expectations, events, conditions or circumstances, except as required by applicable law.

 

Investor Relations and Media Contact

Dr. Sarah Fakih
EVP, Head of Global Communications & Investor Relations
Sarah.Fakih@evotec.com

 

Key figures of consolidated income statement & segment information
 

    Three months ended 30 September 2026   Three months ended 30 September 2025
(in € thousands)   D&PD JEB Evotec Group   D&PD JEB Evotec Group
Revenue   120,086 44,840 164,926   122,892 40,994 163,887
Intersegment revenue   81  __ __   166 103 __
Costs of revenue   (102,460) (42,752) (145,130)   (110,909) (46,495) (157,135)
Gross profit   17,708 2,088 19,796   12,150 (5,397) 6,752
Gross margin   14.7% 4.7% 12.0%   9.9% (13.1)% 4.1%
R&D expenses   (9,344) __ (9,344)   (12,839) (9) (12,848)
SG&A expenses   (30,659) (8,125) (38,784)   (38,036) (6,954) (44,990)
Other operating income   8,587 540 9,127   10,630 1,099 11,730
Other operating expense   (4,323) (3,586) (7,909)   (2,157) (3,097) (5,254)
Reorganization costs   7,003 __ 7,003   108 __ 108
Operating income (loss)   (11,029) (9,083) (20,112)   (30,145) (14,357) (44,502)
Adjusted EBITDA   (1,032) (600) (1,632)   (9,498) (5,538) (15,036)

 

    Nine months ended 30 September 2026   Nine months ended 30 September 2025
(in € thousands)   D&PD JEB Evotec Group   D&PD JEB Evotec Group
Revenue   347,955 117,094 465,049   391,861  143,239 535,100
Intersegment revenue   287 __ __   195 126 __
Costs of revenue   (320,426) (128,262) (448,402)   (338,876) (139,432) (477,987)
Gross profit   27,815 (11,168) 16,647   53,180 3,933 57,114
Gross margin in %   8.0% (9.5)% 3.6%   13.6% 2.7% 10.7%
R&D expenses   (29,682) __ (29,682)   (42,185) (71) (42,256)
SG&A expenses   (97,155) (24,707) (121,862)   (115,815) (22,585) (138,400)
Other operating income   29,553 1,603 31,156   38,516 2,856 41,371
Other operating expense   (53,987) (5,132) (59,119)   (7,224) (3,631) (10,855)
Reorganization costs   (91,922) __ (91,922)   741 __ 741
Operating income (loss)   (215,377) (39,405) (254,781)   (72,786) (19,499) (92,284)
Adjusted EBITDA   (25,470) (18,846) (44,316)   (18,826) 1,940 (16,886)

 


05.11.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Evotec SE
Manfred Eigen Campus / Essener Bogen 7
22419 Hamburg
Germany
Phone: +49 (0)40 560 81-0
E-mail: info@evotec.com
Internet: www.evotec.com
ISIN: DE0005664809
WKN: 566480
Indices: SDAX, TecDAX
Listed: Regulated Market in Frankfurt (Prime Standard), Tradegate BSX; Regulated Unofficial Market in Dusseldorf, Hamburg, Hanover, Munich, Stuttgart; Nasdaq
LEI Code: 529900F9KI6OYITO9B12
EQS News ID: 2428688

 
End of News EQS News Service

2428688  05.11.2026 CET/CEST

PolyPeptide Group: Definitive end result of the public tender offer of Samsung Biologics Co., Ltd.

PolyPeptide Group / Key word(s): Tender Offer

PolyPeptide Group: Definitive end result of the public tender offer of Samsung Biologics Co., Ltd.

05-Nov-2026 / 07:05 CET/CEST

Release of an ad hoc announcement pursuant to Art. 53 LR

The issuer is solely responsible for the content of this announcement.


Media Release – ad hoc announcement pursuant to Art. 53 LR

 

Definitive end result of the public tender offer of Samsung Biologics Co., Ltd.

Baar, Switzerland, 5 November 2026 – Samsung Biologics Co., Ltd. (“Samsung Biologics”), through its direct subsidiary Samsung Peptide AG (“Samsung Peptide”), today published the definitive end result of its public tender offer (the “Offer”) for all publicly held registered shares of PolyPeptide Group AG (“PolyPeptide”) (SIX: PPGN).

The additional acceptance period of the Offer ended on 30 October 2026, at 4:00 p.m. Swiss time. According to the definitive end result as published by Samsung Peptide,

  • the participation of Samsung Peptide and the persons acting in concert with Samsung Peptide amounts to 32,458,892 PolyPeptide shares in aggregate, corresponding to 97.99% of the issued share capital and voting rights of PolyPeptide (participation rate); and
  • 32,350,302 PolyPeptide shares were tendered into the Offer until the end of the additional acceptance period of the Offer, corresponding to 97.66% of the issued share capital and voting rights of PolyPeptide and 97.98% of all PolyPeptide shares to which the Offer relates (success rate).

The definitive end result that has been published today by Samsung Peptide is available at https://samsungbiologics.com/offer.

According to the definitive end result as published by Samsung Peptide, the Offer remains subject to certain remaining Offer conditions, including the receipt of regulatory approvals in certain jurisdictions.

In its provisional end result published on 2 November 2026, Samsung postponed the settlement of the Offer in accordance with section B.7.3 (Period for which the Offer Conditions are in Force and Effect and Deferral) of the offer prospectus of Samsung Peptide dated 31 August 2026 (the “Offer Prospectus”). Samsung confirmed in its provisional and definitive end result that based on the current understanding of the regulatory approval procedures in various countries (see the Offer condition pursuant to section B.7.1(b) (Merger and FDI Clearances) of the Offer Prospectus), the transaction is currently expected to be completed towards the end of 2026 or in Q1 2027.

According to the definitive end result as published by Samsung Peptide, Samsung Peptide intends to pursue a squeeze-out of any remaining public shareholders and to apply to SIX Exchange Regulation for the delisting of the PolyPeptide shares following the settlement of the Offer.

 

Contact

PolyPeptide Group AG
Strategic Marketing and Corporate Communications
Laura Rosso
mediateam@polypeptide.com
T: +41 43 502 0580

PolyPeptide Group AG
Finance / Investor Relations
Tim Brandl
investorrelations@polypeptide.com
T: +41 43 502 0580 

 

About PolyPeptide

PolyPeptide Group AG and its consolidated subsidiaries (“PolyPeptide”) is a specialized Contract Development & Manufacturing Organization (CDMO) for peptide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world. PolyPeptide serves a fast-growing market, offering products and services from pre-pre-clinical to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with significant exposure to metabolic diseases, including GLP-1. Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange. For more information, please visit polypeptide.com.

@PolyPeptide — follow us on LinkedIn

About Samsung Peptide and Samsung Biologics

Samsung Peptide is a direct subsidiary of Samsung Biologics. Samsung Biologics and PolyPeptide have concluded a transaction agreement on 17 July 2026 regarding the Offer. Samsung Peptide is acting as the formal offeror of the Offer. Samsung Biologics (KRX: 207940.KS) is a leading Contract Development & Manufacturing Organization (CDMO), offering end-to-end integrated services that range from late discovery to commercial manufacturing. With a combined biomanufacturing capacity of 785,000 liters across Bio Campus I and II in Korea, and 60,000 from the manufacturing facility in Rockville, Maryland, U.S., Samsung Biologics holds total global manufacturing capacity of 845,000 liters. Samsung Biologics has also secured land for Bio Campus III, laying the groundwork for future capacity expansion to support next-generation therapies and emerging modalities. Samsung Biologics leverages cutting-edge technologies and expertise to advance diverse modalities, including multispecific antibodies, fusion proteins, antibody-drug conjugates, and mRNA therapeutics. By implementing the ExellenS™ framework across its manufacturing network with standardized designs, unified processes, and advanced digitalization, Samsung Biologics ensures plant equivalency and speed for manufacturing continuity. Samsung Biologics’ global manufacturing and commercial network spans Korea, the U.S., Europe, and Japan. Samsung Biologics continues to invest in new capabilities to maximize operational and quality excellence, ensuring flexibility and agility for clients. Samsung Biologics is committed to the on-time, in-full delivery of safe, high-quality biomedicines, as well as to making sustainable business decisions for the betterment of society and global health. For more information, please visit https://samsungbiologics.com.

Legal Notice and Disclaimer

No Offer / Offer Restrictions

The information in this media release is for informational purposes only. It does not constitute, or form part of, any offer or invitation to purchase, sell, exchange or issue, or any solicitation of an offer to sell, purchase, exchange or subscribe to, any registered shares or other securities of PolyPeptide or any other person, nor shall it form the basis of, or be relied upon in connection with, any contract in relation thereto. This media release is not part of Samsung Peptide’s publication of the definitive end result of the Offer or any other publication, communication or other documentation of Samsung Peptide or Samsung Biologics relating to the Offer, including without limitation the Offer Prospectus (the “Offer Documentation”). Terms and conditions of the Offer have been published by Samsung Peptide and Samsung Biologics in the Offer Documentation. Shareholders of PolyPeptide are urged to read the Offer Documentation, which is available at https://samsungbiologics.com/offer.

This announcement is not for publication, release or distribution in any country or jurisdiction in which it would be considered unlawful or otherwise violate any applicable laws or regulations, or which would require Samsung Peptide or Samsung Biologics to change or amend the terms or conditions of the Offer in any way, to make an additional filing with any governmental, regulatory or other authority or take additional action in relation to the Offer. Full Offer restrictions can be found in Samsung Peptide’s Offer Prospectus at https://samsungbiologics.com/offer.

Forward-looking Information and Statements

This media release has been prepared by PolyPeptide and includes forward-looking information and statements concerning the outlook for the Group’s business. These statements are based on current expectations, estimates and projections about the factors that may affect the Group’s future performance. These expectations, estimates and projections are generally identifiable by statements containing words such as ‘expects’, ‘believes’, ‘estimates’, ‘targets’, ‘plans’, ‘projects’, ‘outlook’ or similar expressions. There are numerous risks, uncertainties and other factors, many of which are beyond PolyPeptide’s control, that could cause the group’s actual results to differ materially from the forward-looking information and statements made in this media release and that could affect the group’s ability to achieve its stated targets. Although PolyPeptide believes that its expectations reflected in any such forward-looking statement are based upon reasonable assumptions, it can give no assurance that those expectations will be achieved.

Except as otherwise required by law, PolyPeptide disclaims any intention or obligation to update any forward-looking statements as a result of developments.

 

Additional features:

File: 20261105_PolyPeptide_Media_Release_Tender_Offer


End of Inside Information


Language: English
Company: PolyPeptide Group
Neuhofstrasse 24
6340 Baar
Switzerland
Phone: +41435020580
E-mail: mediateam@polypeptide.com
Internet: www.polypeptide.com
ISIN: CH1110760852
Valor: 111076085
Listed: SIX Swiss Exchange
EQS News ID: 2428776

 
End of Announcement EQS News Service

2428776  05-Nov-2026 CET/CEST

AEVIS VICTORIA SA: Continued Revenue Growth in the Third Quarter of 2026

AEVIS VICTORIA SA / Key word(s): 9 Month figures

AEVIS VICTORIA SA: Continued Revenue Growth in the Third Quarter of 2026

05-Nov-2026 / 07:00 CET/CEST

Release of an ad hoc announcement pursuant to Art. 53 LR

The issuer is solely responsible for the content of this announcement.


Ad hoc announcement pursuant to Art. 53 LR

Fribourg, 5 November 2026

AEVIS VICTORIA SA: Continued Revenue Growth in the Third Quarter of 2026

Consolidated gross revenue up 8.2% (7.7% organic), driven by healthcare. Net revenue stable at CHF 789.4 million, up 0.6% on a like-for-like basis.

In the first nine months of 2026, AEVIS VICTORIA SA generated consolidated gross revenue of CHF 972.7 million (9M 2025: CHF 899.2 million), an increase of 8.2%. Net revenue, the Group’s key reference metric, amounted to CHF 789.4 million (9M 2025: CHF 789.9 million), stable (-0.1%). Excluding scope effects and the sale of apartments in Zermatt recognized in 2025, net revenue grew by 0.6%.

The growth in gross revenue mainly reflects the presentation of fees of independent physicians at Swiss Medical Network. These fees are recognized in gross revenue and then passed through as third-party services; they amounted to CHF 183.3 million (9M 2025: CHF 109.3 million). Net revenue, which excludes these fees, is the Group’s key reference metric.

Healthcare: Solid Growth and Integration of Radiologia Ticino
Swiss Medical Network, which operates 18 clinics and hospitals and 80 outpatient centers, generated gross revenue of CHF 804.2 million (9M 2025: CHF 722.6 million), up 11.3% (10.7% organic). Net revenue rose 1.2% to CHF 620.9 million (9M 2025: CHF 613.3 million). On a constant scope basis, i.e., excluding Radiologia Ticino, which has been consolidated since January 1, 2026, growth was 0.5%, or 1.6% excluding the impact of the restructuring of Privatklinik Lindberg.

The hospital business posted gross revenue of CHF 632.9 million (+12.2%) and net revenue of CHF 466.3 million, a slight decrease of 0.5% (+0.8% excluding Privatklinik Lindberg). The outpatient business recorded gross revenue of CHF 91.6 million (+6.2%) and net revenue of CHF 80.0 million (+5.2%), of which CHF 4.4 million was contributed by Radiologia Ticino.

The transfer of Privatklinik Lindberg’s medical activities to the Bethanien (Zurich) and Belair (Schaffhausen) clinics has been completed; Kantonsspital Winterthur took over the premises on October 1, 2026. The full positive impact of this measure will be felt from fiscal year 2027. The continuous improvement in profitability over the first nine months, combined with the restructuring measures implemented, provides a solid foundation for the remainder of fiscal year 2026 and for 2027.

Hospitality: Higher Average Rates and Acceleration at Period-End
MRH Switzerland AG, the Group’s hospitality division managed by Michel Reybier Hospitality, generated revenue of CHF 159.5 million (9M 2025: CHF 157.4 million), up 1.3%, entirely organic. The average daily rate rose 5.4% to CHF 607 and revenue per available room (RevPAR) 5.1% to CHF 348, with occupancy virtually stable at 57.4%. Momentum picked up significantly toward the end of the period, with September revenue up 9.2%.

Real Estate: Rental Income Up 12.2%
Swiss Hotel Properties SA generated revenue of CHF 29.5 million (9M 2025: CHF 36.1 million). The decline reflects the comparison base, which included CHF 10.1 million in gains on the sale of apartments in Zermatt (CHF 0.3 million in 2026). Rental income rose 12.2% to CHF 29.2 million.

For further information
Media and Investor Relations: c/o Dynamics Group, Zurich
Marion Schihin, msc@dynamicsgroup.ch, +41 79 705 88 15

AEVIS VICTORIA SA – Investing for a better life
AEVIS VICTORIA SA invests in healthcare, hospitality & lifestyle and infrastructure. AEVIS’s main shareholdings are Swiss Medical Network Holding SA (76.3%, directly and indirectly), the only Swiss private network of hospitals present in the country’s three main language regions, MRH Switzerland AG, a luxury hotel group managing eleven hotels in Switzerland and abroad, Infracore SA (22.6%, directly and indirectly), a listed real estate company (INFRAC.SW) dedicated to healthcare-related infrastructure, Swiss Hotel Properties SA, a hospitality real estate division, and NESCENS SA, a brand dedicated to better aging. AEVIS is listed on the Swiss Reporting Standard of the SIX Swiss Exchange (AEVS.SW). www.aevis.com.


End of Inside Information


2428694  05-Nov-2026 CET/CEST

Topadur’s Phase 2a Trial of TOP-N53 for Systemic Sclerosis-Associated Digital Ulcers Advances to Next Dose Levels

Topadur Pharma AG

/ Key word(s): Study

Topadur’s Phase 2a Trial of TOP-N53 for Systemic Sclerosis-Associated Digital Ulcers Advances to Next Dose Levels

05.11.2026 / 07:00 CET/CEST

The issuer is solely responsible for the content of this announcement.


Topadur’s Phase 2a Trial of TOP-N53 for Systemic Sclerosis-Associated Digital Ulcers Advances to Next Dose Levels

Schlieren-Zurich, Switzerland, 05 November 2026 – Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced that the Safety Review Committee of its Phase 2a trial has recommended progression to the next planned dose levels. The trial is evaluating lead candidate TOP-N53 for the treatment of systemic sclerosis-associated digital ulcers. The recommendation follows a review of safety data and the completion of the first patient cohort. No protocol-defined stopping criteria were met, and no serious adverse drug reactions were reported.

TOP-N53 is a novel, bifunctional topical therapeutic candidate designed to improve microcirculation and support tissue repair. By combining nitric oxide (NO) release and phosphodiesterase-5 (PDE5) inhibition in a single small molecule, TOP-N53 aims to enhance cGMP signaling directly at the site of application. Its clinical development builds on a first-in-human Phase 1 study in healthy volunteers, which demonstrated favorable tolerability and increased local skin perfusion following subcutaneous administration. TOP-N53 holds orphan drug designation in both the US and the European Union for the treatment of systemic sclerosis-associated digital ulcers. The ongoing open-label, vehicle-controlled Phase 2a trial (NCT06954597), conducted in Switzerland and France, evaluates the safety and tolerability of ascending doses of TOP-N53 applied topically to digital ulcers in patients with systemic sclerosis.

“TOP-N53 is a key program for Topadur as we investigate the potential of locally acting therapies to address diseases with significant unmet medical needs,” said PD Dr. Matthias Schäfer, CEO of Topadur Pharma AG. “With the Safety Review Committee’s recommendation to proceed to the next dose levels, we have reached an important milestone in the clinical development of TOP-N53. We are grateful to the patients and clinical teams whose participation and dedication make it possible to move this clinical trial forward.”

Systemic sclerosis is a rare autoimmune disease characterized by damage to small blood vessels and fibrosis of the skin and internal organs. About half of patients develop digital ulcers, painful wounds on the fingers that are often slow to heal and prone to recurrence. Treatment options for existing ulcers remain limited, and current drug treatments act systemically. A 2025 consensus report by the World Scleroderma Foundation[i] highlights the significant unmet medical need for local treatment strategies for digital ulcers.

“Even a single digital ulcer can cause significant pain and severely affect a patient’s daily life, making activities as simple as buttoning a shirt or holding a pen difficult,” said Prof. Marie-Elise Truchetet, Department of Rheumatology, CHU de Bordeaux, France, and Principal Investigator at the Bordeaux study site. “There is a clear need for new local treatment options. Evaluating the safety and tolerability of TOP-N53 at increasing doses is an important step towards understanding its potential for patients with digital ulcers.”

The trial is part of a start-up innovation project supported by Innosuisse. Recruitment for the second cohort is scheduled to begin in November at six clinical centers in Switzerland and France, coinciding with the colder months, when new digital ulcers occur more frequently.

About Topadur Pharma AG
Topadur Pharma AG, based in Schlieren-Zurich, Switzerland, is a clinical-stage biopharmaceutical company developing locally acting small-molecule therapies. Its proprietary DualTOP® platform targets the cGMP signaling pathway, a central regulator of vascular regeneration and tissue repair. Building on this technology, the company is advancing a pipeline of therapeutic candidates for age- and disease-related conditions with significant unmet medical needs. Topadur’s lead candidate, TOP-N53, is undergoing Phase 2a clinical evaluation for the treatment of digital ulcers in patients with systemic sclerosis. In parallel, TOP-M119 is being prepared for first-in-human clinical trials targeting alopecia. For more information, please visit www.topadur.com and follow us on LinkedIn.

Contacts

Topadur Pharma AG
Yoshita Bhide
Media Communications
+41 44 755 44 66
yoshita.bhide@topadur.com

Media inquiries:
MC Services

Anne Hennecke, Julia Bittner
+49 89 210 2280
contact@mc-services.eu
 

Disclaimer

TOP-N53 is an investigational product and has not been approved by Swissmedic, the European Commission, the US Food and Drug Administration or any other regulatory authority. Its safety and efficacy have not been established. Observations from the first cohort are preliminary, based on a small number of patients treated at the lowest dose in an open-label setting, and may not predict results at higher doses or of the completed trial. This press release is intended for media and investors; it does not promote any medicinal product, provide medical advice or invite participation in a clinical trial.

This communication does not constitute an offer or invitation to subscribe for or purchase any securities of Topadur Pharma AG. This publication contains forward-looking statements and assessments or intentions concerning the company and its business. Such statements involve certain risks, uncertainties and other factors which could cause the actual results, financial condition, performance or achievements of the company to be materially different from those expressed or implied by such statements. Readers should therefore not place reliance on these statements, particularly not in connection with any contract or investment decision. The company disclaims any obligation to update these forward-looking statements, assessments or intentions.

 

[i] Campochiaro C, et al. “Recommendations for the local management of digital ulcers in systemic sclerosis: A report from the World Scleroderma Foundation (WSF) ‘Ad hoc committee’.” J Scleroderma Relat Disord 2025;10(3):276–284. https://doi.org/10.1177/23971983251339821


05.11.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


2428542  05.11.2026 CET/CEST

Viromed Medical AG Receives Approval for ViroCAP® med in Turkey and Announces Further Operational Progress

Viromed Medical AG

/ Key word(s): Miscellaneous

Viromed Medical AG Receives Approval for ViroCAP® med in Turkey and Announces Further Operational Progress

04.11.2026 / 16:20 CET/CEST

The issuer is solely responsible for the content of this announcement.


Viromed Medical AG Receives Approval for ViroCAP® med in Turkey and Announces Further Operational Progress

Rellingen, November 4, 2026 – Viromed Medical AG (“Viromed”; ISIN: DE000A3MQR65), a medical technology company and pioneer of cold plasma technology, has received approval in Turkey for its medical device ViroCAP® med (MDR Class IIa). The product is now approved for medical applications on the Turkish market, in particular for the treatment of open wounds and intraoperative use.

Uwe Perbandt, CEO of Viromed Medical AG: “The approval of ViroCAP® med in Turkey is a significant success for our international market development. Following the registration of ViroCAP® derma with the ÜTS (National Medical Device Tracking System) in the summer, we have already received approval for ViroCAP® med, which we had expected no earlier than February or March 2027. This marks another important milestone for the commercial launch of our ViroCAP® technology in a healthcare market that is strategically important for us.”

Viromed already has binding minimum orders for 7,000 ViroCAP® derma/med devices through the end of 2028 for the Turkish market. Deliveries will be made on the basis of the approval now granted.

The required process for reimbursement by Turkish health insurers is already running in parallel. With this approval, Viromed continues its international expansion strategy and lays the foundation for the further development of the Turkish market.

ViroCAP® med is designed for professional use by qualified medical personnel and supports the treatment of open wounds as well as intraoperative use of cold atmospheric plasma. The application is contactless and mobile. Each application is planned to last one to two minutes, while skin temperature remains below 40 degrees Celsius.

Additional Local Approval Procedures Initiated

In parallel, Viromed together with its partner Umeco has started the approval process for ViroCAP® med in additional Asian countries. A prerequisite for this was likewise the prior approval of the product as an MDR Class IIa medical device in the EU. Outside the EU, a local approval in each target country is required, which is being pursued together with the distribution partners.

First Reimbursement by a Health Insurer – Selective Contract in Lower Saxony

Viromed has also achieved its first reimbursement of ViroCAP® by a statutory health insurer. A selective contract was concluded with a health insurer in Lower Saxony for an indication in the intensive care area: the treatment of patients with a left ventricular assist device (LVAD). The focus is on preventing infections at the driveline exit site.

Viromed is also in advanced discussions for further selective contracts with health insurers in three additional German federal states.

Further Studies

In November, a successfully completed retrospective study on the prevention of postoperative wound infections will be published. In addition, Viromed is starting a randomized study on the use of ViroCAP® in LVAD patients as well as a further study on the use of the technology in the field of heart valves.

 

About Viromed Medical AG

Viromed Medical AG specializes in the development, manufacture and distribution of medical products. The operating business of the company, which has been listed on the stock exchange since October 2022, focuses on the distribution of innovative cold plasma technology for medical applications via its wholly owned subsidiary Viromed Medical GmbH. Viromed can draw on a broad customer base in the DACH region and beyond. Viromed is pursuing the goal of further advancing the use of cold plasma technology in medicine in the coming years and realizing the corresponding growth potential.

www.viromed-medical-ag.de

Contact Viromed

E-Mail: kontakt@viromed-medical.de
 

Press contact

E-mail: viromed@kirchhoff.de


04.11.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Viromed Medical AG
Hauptstraße 105
25462 Rellingen
Germany
E-mail: kontakt@viromed-medical.de
Internet: https://www.viromed-medical-ag.de/
ISIN: DE000A40ZVN7
WKN: A40ZVN
Listed: Regulated Unofficial Market in Dusseldorf, Frankfurt, Hamburg, Tradegate BSX
LEI Code: 894500XR05MYCVCCR171
EQS News ID: 2428580

 
End of News EQS News Service

2428580  04.11.2026 CET/CEST

Heidelberg Pharma to Present New Clinical Data on its ATAC Candidates at the ASH Annual Meeting 2026

Heidelberg Pharma AG

/ Key word(s): Conference

Heidelberg Pharma to Present New Clinical Data on its ATAC Candidates at the ASH Annual Meeting 2026

04.11.2026 / 16:36 CET/CEST

The issuer is solely responsible for the content of this announcement.


PRESS RELEASE

Heidelberg Pharma to Present New Clinical Data on its ATAC Candidates at the ASH Annual Meeting 2026

Ladenburg, Germany, 4 November 2026 – Heidelberg Pharma AG (FSE: HPHA), a clinical stage company developing innovative Antibody Drug Conjugates (ADCs), will present new data from its Phase I/IIa clinical study with its lead Amanitin-based ADC candidate, pamlectabart tismanitin (HDP-101), in an oral presentation, as well as data from its second clinical candidate, HDP-102, during the poster abstract session of the 68th Annual Meeting of the American Society of Hematology (ASH), being held in New Orleans, USA, from 12 to 15 December 2026.

Details of the oral presentation (HDP-101):

Presentation title: First-in-human phase 1/2a study of pamlectabart tismanitin (HDP-101), an amanitin-based BCMA-targeting antibody-drug conjugate (ADC): Recommended phase 2 dose (RP2D) selection and preliminary antitumor activity in relapsed/refractory multiple myeloma (RRMM)

Presenter: Professor Marc-Steffen Raab, MD
Publication number: 270
Session: 654. Multiple Myeloma: Pharmacologic Therapies: Novel Approaches in Relapsed Myeloma: Immunotherapies and Small Molecules
Session time: Saturday, 12 December 2026, 02:00 – 03:30 pm (CDT)
Presentation: Saturday, 12 December 2026, 03:15 – 03:30 pm (CDT)
Room: Ernest N. Morial Convention Center (MCCNO) –
La Nouvelle A-B
Link to the abstract: ASH® ANNUAL PROGRAM

Pamlectabart tismanitin is an anti-BCMA antibody-Amanitin drug conjugate for the treatment of relapsed or refractory multiple myeloma (RRMM), a bone marrow cancer with a high unmet medical need. Phase I of the trial was a dose-escalation study to determine a dose level of the candidate for the Phase IIa expansion part of the study.

The Phase I part of the study included ten patient cohorts and was completed in April 2026, and the recommended dose for the Phase IIa expansion part (Recommended Phase 2 Dose; RP2D) was determined. The Phase IIa is progressing as planned.

Pamlectabart tismanitin demonstrated consistent clinical activity with a favorable safety profile in heavily pretreated RRMM patients supporting the potential of the candidate as a novel payload BCMA-targeted ADC therapy.

Details of the poster presentation (HDP-102):

Presentation title: HDP-102, a first-in-class CD37-targeted amanitin-based antibody-drug conjugate, demonstrates translational activity, favorable early safety and efficacy in relapsed/refractory (R/R) B-cell malignancies

Presenter: Dr. Irina Mocanu, MD
Publication number: 3717
Session: 629: Aggressive Lymphomas, Non-Cellular Immunotherapy including Bispecific Antibodies: Poster II
Session time: Sunday, 13 December 2026, 06:00 – 08:00 pm (CDT)
Presentation: Sunday, 13 December 2026, 06:00 – 08:00 pm (CDT)
Room: Ernest N. Morial Convention Center (MCCNO) –
Hall F
Link to the abstract: ASH® ANNUAL PROGRAM

HDP-102 is an ADC targeting CD37, which is overexpressed on B-cell lymphoma cells. Preclinical studies have shown excellent anti-tumor efficacy in in vivo studies as well as good tolerability. HDP-102 is intended to be developed for specific indications of non-Hodgkin lymphoma.

In 2025, Heidelberg Pharma announced the dosing of the first patient with HDP-102. Three patients were treated with 40 µg/kg in the first cohort. The treatment was well tolerated, and initial signs of biological activity have been observed already at the very low dose. Two patients showed stabilization of the disease with regression and reduction of lymph nodes. The safety committee recommended increasing the dose of HDP-102 to 65 µg/kg in cohort 2.

In line with Heidelberg Pharma’s strategic decision from September 2025 to discontinue the study, the Company is exploring partnership opportunities to support the continuation of the program.

 

About Heidelberg Pharma

Heidelberg Pharma is the first company to develop cancer therapies using Amanitin, a compound derived from the green death cap mushroom. The biological mechanism of action of the toxin represents a new therapeutic modality and is used as a compound in the Amanitin-based ADC technology, the so-called ATAC technology.

Lead candidate HDP-101 (INN: pamlectabart tismanitin) is a BCMA ATAC in clinical development for multiple myeloma. The candidate has been granted Orphan Drug Designation and Fast Track Designation from the FDA. A second ATAC candidate, HDP-102 is in clinical development stage in Non-Hodgkin Lymphoma. HDP-103 against metastatic castration-resistant prostate cancer and HDP-104 targeting gastrointestinal tumors such as colorectal cancer have completed preclinical development. These programs are available for partnering.

The company is based in Ladenburg, Germany, and is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol HPHA. More information is available at http://www.heidelberg-pharma.com/.

ATAC® is a registered trademark of Heidelberg Pharma Research GmbH.

Contact
Heidelberg Pharma AG
Sylvia Wimmer
Senior Director Corporate Communications
Tel.: +49 6203 1009 1004
E-mail: investors@hdpharma.com
Wallstadter Straße 59, 68526 Ladenburg
IR/PR-Support
MC Services AG
Katja Arnold (CIRO)
Managing Director & Partner
Tel.: +49 89 210 228-40
E-mail: katja.arnold@mc-services.eu  
 

 

This communication contains certain forward-looking statements relating to the Company’s business, which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “will” “should” “future”, “potential” or similar expressions or by a general discussion of the Company’s strategy, plans or intentions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results of operations, financial condition, performance, or achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors and partners are cautioned not to place undue reliance on such forward-looking statements. We disclaim any obligation to update any such forward-looking statements to reflect future events or developments.


04.11.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Heidelberg Pharma AG
Wallstadter Straße 59
68526 Ladenburg
Germany
Phone: +49 6203 10090
E-mail: investors@hdpharma.com
Internet: www.heidelberg-pharma.com
ISIN: DE000A11QVV0
WKN: A11QVV
Listed: Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Dusseldorf, Munich, Stuttgart, Tradegate BSX
LEI Code: 391200E09XYBYITR1W32
EQS News ID: 2428588

 
End of News EQS News Service

2428588  04.11.2026 CET/CEST

Lonza CEO Wolfgang Wienand to present at Jefferies Global Healthcare Conference

Basel, Switzerland, 4 November 2026 – Lonza is pleased to announce that it will participate in the Jefferies Global Healthcare Conference in London on 17 and 18 November 2026.

As part of the conference, Lonza CEO Wolfgang Wienand will host a presentation and subsequent Q&A on 18 November from 15:30 – 15:55 GMT (16:30 – 16:55 CET). 

The session will be webcast live, and a replay will be available on the Lonza Investor Relations website, remaining accessible for 90 days.

The live audio webcast can be accessed via this link.

BRAIN Biotech and Syngenta form strategic cooperation applying synthetic biology to drive innovations in sustainable farming solutions  

BRAIN Biotech AG

/ Key word(s): Alliance

BRAIN Biotech and Syngenta form strategic cooperation applying synthetic biology to drive innovations in sustainable farming solutions  

04.11.2026 / 10:45 CET/CEST

The issuer is solely responsible for the content of this announcement.


BRAIN Biotech and Syngenta form strategic cooperation applying synthetic biology to drive innovations in sustainable farming solutions

  • Strategic Cooperation uses synthetic biology to drive innovations for biologicals in agriculture
  • BRAIN Biotech provides access to its proprietary BioArchive and its expertise in advanced microbial strain development

ZWINGENBERG, Germany, November 4, 2026 – BRAIN Biotech AG, a leading provider of specialized enzymes and innovative biosolutions for industry, and Syngenta, a global leader in agricultural innovation, join forces to accelerate the development of biologicals.

The companies strategically combine BRAIN Biotech´s scientific expertise in synthetic biology with Syngenta’s global leadership in biologicals to support the development of next-generation agricultural solutions and address key challenges in sustainable farming.

BRAIN Biotech will contribute its advanced microbial strain development capabilities to support Syngenta’s research initiatives aimed at expanding the potential of novel biologicals. These nature-inspired tools shall complement traditional crop protection solutions and aim to enhance plant health, resilience and productivity.

“Partnering with a global leader like Syngenta underscores the importance of biological innovation for sustainable agriculture,” says Martin Langer, EVP at BRAIN Biotech. “We see this collaboration as a powerful way to combine our extensive industrial biotechnology toolset with Syngenta’s scale and field-driven insights to create solutions which positively impact farmers as well as the environment.”

“At Syngenta, we believe agricultural innovation unlocks the next-generation of sustainable farming solutions and are committed to working with partners who share the same vision,” says Jérôme Cassayre, Syngenta’s Head Biologicals Research. “We’re excited to work with BRAIN Biotech to push back the boundaries of science in agricultural biologicals.”

BRAIN Biotech offers highly specialized microbiological services, including the identification and optimization of strains to produce enzymes and biomolecules. The company’s extensive portfolio of biotechnological methods and customer-oriented service are key to delivering innovative, next-generation solutions and products. These are now combined under the new industrial biotechnology brand BRAINBiocatalysts. Customers also get access to the BRAIN BioArchive, a collection of tens of thousands of unique microbial strains and can search for specific strains tailored to their applications.

+++

Contact Investor Relations and Media

Martina Schuster

Phone: +49 6251 9331-69

Email: martina.schuster@brainbio.com

 

BRAINBiocatalysts

BRAINBiocatalysts is the industrial biotechnology brand of the BRAIN Biotech Group. BRAINBiocatalysts combines expertise across discovery, development, scale-up and manufacturing to deliver scalable bio-based solutions for complex challenges and specialty applications. Its capabilities span enzyme discovery and development, microbial strain development, bioprocess development, application expertise and commercial manufacturing.

BRAINBiocatalysts brings together the capabilities of BRAIN Biotech AG, Biocatalysts Ltd., Breatec B.V., WeissBiotech GmbH and Biocatalysts Inc. The respective legal entities provide products and services and enter into contractual relationships with customers. For more information visit: www.brainbiocatalysts.com

 

BRAIN Biotech Group

The BRAIN Biotech Group develops and provides bio-based products and solutions for industry, with activities organized in two business segments: BRAINBiocatalysts (development, production, and distribution of specialty enzymes, microorganisms, and ingredients) and BRAINBioIncubator (research-intensive development projects and pharmaceuticals). BRAIN Biotech AG, the parent company of the BRAIN Biotech Group operates its own fermentation facilities in the UK and has additional production sites in continental Europe and the US. BRAIN Biotech AG has been listed on the Frankfurt Stock Exchange since February 9, 2016 (Ticker: BNN; ISIN: DE0005203947 / WKN: 520394). In fiscal year 2024/25, the group generated revenue of €49.6 million with around 280 employees.

For more information, visit: www.brain-biotech-group.com

 

Disclaimer

This press release contains forward-looking statements. These statements reflect the current views, expectations, and assumptions of the management of BRAIN Biotech AG, and are based on information currently available to the management.

Forward-looking statements are no guarantees of future performance, and entail both known and unknown risks as well as uncertainties that could cause actual results, performance or events to differ materially from those expressed or implied in such statements. Numerous factors exist that could influence the future performance of and future developments at BRAIN Biotech AG and the BRAIN Biotech Group. Such factors include, but are not limited to, changes in the general economic and competitive environment, risks associated with capital markets, currency exchange rate fluctuations, changes in international and national laws and regulations, in particular with respect to tax laws and regulations, as well as other factors.

BRAIN Biotech AG does not undertake any obligation to update or revise any forward-looking statements.

 


04.11.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: BRAIN Biotech AG
Darmstädter Straße 34-36
64673 Zwingenberg
Germany
Phone: +49 (0) 62 51 / 9331-0
Fax: +49 (0) 62 51 / 9331-11
E-mail: ir@brainbio.com
Internet: www.brain-biotech-group.com
ISIN: DE0005203947
WKN: 520394
Listed: Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Dusseldorf, Hamburg, Munich, Stuttgart, Tradegate BSX
LEI Code: 391200JKPVHLD6JLZ107
EQS News ID: 2428236

 
End of News EQS News Service

2428236  04.11.2026 CET/CEST

TeleClinic, a subsidiary of DocMorris, expands into Switzerland: Acquisition of the telemedicine provider Medi24

DocMorris AG

/ Key word(s): Mergers & Acquisitions

TeleClinic, a subsidiary of DocMorris, expands into Switzerland: Acquisition of the telemedicine provider Medi24

04.11.2026 / 07:47 CET/CEST


Frauenfeld, 4 November 2026

Press release

TeleClinic, a subsidiary of DocMorris, expands into Switzerland: Acquisition of the telemedicine provider Medi24

  • First step toward the international rollout of the telemedicine offering
  • Accelerated scaling of the successful TeleClinic platform
  • Significant potential for synergies already in the first year

TeleClinic, Germany’s leading telemedicine platform and a subsidiary of DocMorris, is expanding into Switzerland. This move begins with the acquisition of Medi24 — one of Switzerland’s leading telemedicine providers, based in Liebefeld — from Allianz Partners. By entering the Swiss market, TeleClinic takes its first step toward rolling out the core technology of its successful telemedicine platform to other European countries. For DocMorris, the acquisition is a key building block for further scaling its Digital Services business.

Medi24 is closely linked to the largest Swiss health insurers through numerous partnerships. The company offers contractually guaranteed initial access to telemedicine to over 4.6 million insured persons. This corresponds to around 50 per cent of all insured persons in Switzerland. TeleClinic and Medi24 will continue to operate independently in their respective local markets in order to address the national legal frameworks in an optimal manner.

On a full-year 2026 basis, Medi24’s revenue contribution will nearly double TeleClinic’s expected revenue. The acquisition will make a substantial contribution to TeleClinic’s EBITDA already in the first year. This is made possible by the integration of TeleClinic’s established technology into Medi24’s infrastructure and the resulting cost synergies. The purchase price (enterprise value) is in the low double-digit million CHF range and will be financed through internal funds, debt and equity.

CEO Walter Hess says: “The acquisition of Medi24 and its integration with the TeleClinic platform fit perfectly into DocMorris’s strategy. By leveraging our technological expertise and capacity for innovation, we are purposefully expanding the range of digital health services for the benefit of patients in Switzerland, while making it easier for them to access straightforward care. We look forward to actively further developing digital healthcare together with the experienced team at Medi24.”

The transaction is expected to be completed in December 2026.

 

Investors and analyst contact
Kelvin Jörn, Head of Investor Relations
Email: ir@docmorris.com, phone: +41 52 560 58 10

Media contact
Torben Bonnke, Director Communications
Email: media@docmorris.com, phone: +49 171 864 888 1

Agenda

12 November 2026 Capital Markets Day in Heerlen (NL)
19 January 2027 Revenue 2026
18 March 2027 2026 Full-year results and outlook 2027 (hybrid/Zurich, conference call/webcast)
15 April 2027 Q1/2027 Trading Update
12 May 2027 Annual General Meeting, Zurich

 

DocMorris
The Swiss-based DocMorris AG is a leading company in the fields of online pharmacy, telemedicine and marketplace with strong brands in Germany and other European countries. Deliveries are mainly from the highly automated logistics centre in Heerlen, the Netherlands. TeleClinic is Germany’s largest telemedicine platform, connecting patients with more than 6,500 doctors. DocMorris operates leading marketplaces for health and personal care products in Southern Europe. With its broad range of products and services, DocMorris is pursuing its vision of becoming the leading digital health companion for everyone to manage their health in one click. Around 1,600 employees in Germany, the Netherlands, Spain, France, Portugal and Switzerland generated an external revenue of CHF 1,186 million serving over 12 million active customers in 2025. The shares of DocMorris AG are listed on the SIX Swiss Exchange (securities number 4261528, ISIN CH0042615283, ticker DOCM). For further information, please visit corporate.docmorris.com.

 

Disclaimer
This announcement contains certain forward-looking statements about DocMorris AG and its business, either explicitly or implicitly. Such statements involve known and unknown risks, uncertainties and other factors that could cause the actual results, financial position, performance or achievements of DocMorris AG to differ materially from the future results, performance or achievements expressed or implied by such forward-looking statements. DocMorris AG is making this announcement available as of today’s date and undertakes no obligation to update the forward-looking statements contained herein as a result of new information, future events or for any other reason.

 

 

 


End of Media Release


Language: English
Company: DocMorris AG
Walzmühlestrasse 49
8500 Frauenfeld
Switzerland
ISIN: CH0042615283
Listed: SIX Swiss Exchange
EQS News ID: 2427928

 
End of News EQS News Service

2427928  04.11.2026 CET/CEST