Savara Announces Participation in Upcoming Investor Healthcare Conferences




Savara Announces Participation in Upcoming Investor Healthcare Conferences

LANGHORNE, Pa.–(BUSINESS WIRE)–Savara Inc. (Nasdaq: SVRA) (the “Company”), a clinical stage biopharmaceutical company focused on rare respiratory diseases, today announced members of the management team will host 1×1 meetings and present at two upcoming healthcare conferences.

Wells Fargo Securities Healthcare Conference

September 3, 2025, 4:30pm ET/1:30pm PT

H.C. Wainwright Global Healthcare Conference

September 9, 2025, 1:00pm ET/10:00am PT

The live webcasts and subsequent replays will be available on the “Events & Presentations” section of the Company’s corporate website and will be archived for 90 days.

About Savara

Savara is a clinical stage biopharmaceutical company focused on rare respiratory diseases. Our lead program, MOLBREEVI*, is a recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis (aPAP). MOLBREEVI is delivered via an investigational eFlow^® Nebulizer System (PARI Pharma GmbH) specifically developed for inhalation of a large molecule. Our management team has significant experience in rare respiratory diseases and pulmonary medicine, identifying unmet needs, and effectively advancing product candidates to approval and commercialization. More information can be found at www.savarapharma.com and LinkedIn.

*MOLBREEVI is the FDA and EMA conditionally accepted trade name for molgramostim inhalation solution. It is not approved in any indication. MOLBREEVI is a trademark of Savara Inc.

Contacts

Media and Investor Relations Contact
Savara Inc.

Temre Johnson, Executive Director, Corporate Affairs

ir@savarapharma.com

Arcturus Therapeutics to Attend Upcoming Investor Conferences




Arcturus Therapeutics to Attend Upcoming Investor Conferences

SAN DIEGO–(BUSINESS WIRE)–$ARCT #ClinicalTrial–Arcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a commercial messenger RNA medicines company focused on the development of liver and respiratory rare disease therapeutics and infectious disease vaccines, today announced that the Company will participate in the following investor conferences:

Citi’s 2025 Biopharma Back to School Conference (Fireside Chat)

• Tuesday, September 2, 2025 (11:15 a.m. ET)

2025 Wells Fargo Healthcare Conference (Fireside Chat)

• Wednesday, September 3, 2025 (8:00 a.m. ET)

Cantor Global Healthcare Conference (Fireside Chat)

• Friday, September 5, 2025 (8:00 a.m. ET)

H.C. Wainwright 27^th Annual Global Investment Conference (Presentation)

• Tuesday, September 9, 2025 (8:30 a.m. ET)

About Arcturus

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) is a commercial mRNA medicines and vaccines company with enabling technologies: (i) LUNAR® lipid-mediated delivery, (ii) STARR® mRNA technology (sa-mRNA) and (iii) mRNA drug substance along with drug product manufacturing expertise. Arcturus developed KOSTAIVE®, the first self-amplifying messenger RNA (sa-mRNA) COVID vaccine in the world to be approved. Arcturus has an ongoing global collaboration for innovative mRNA vaccines with CSL Seqirus, and a joint venture in Japan, ARCALIS, focused on the manufacture of mRNA vaccines and therapeutics. Arcturus’ pipeline includes RNA therapeutic candidates to potentially treat OTC deficiency and cystic fibrosis (CF), along with its partnered mRNA vaccine programs for SARS-CoV-2 (COVID-19) and influenza. Arcturus’ versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, circular RNA, antisense RNA, self-amplifying RNA, DNA, and gene editing therapeutics. Arcturus’ technologies are covered by its extensive patent portfolio (over 500 patents and patent applications in the U.S., Europe, Japan, China, and other countries). For more information, visit www.ArcturusRx.com. In addition, please connect with us on X (formerly Twitter) and LinkedIn.

Contacts

Arcturus Therapeutics

Public Relations & Investor Relations

Neda Safarzadeh

VP, Head of IR/PR/Marketing

(858) 900-2682
IR@ArcturusRx.com

Superbug Survivor and Turn Therapeutics CEO Launches Podcast to Spotlight Hidden Scientific Breakthroughs




Superbug Survivor and Turn Therapeutics CEO Launches Podcast to Spotlight Hidden Scientific Breakthroughs

Asking the Tough Question: “The Cures Exist. Why Don’t We Have Them?”

LOS ANGELES–(BUSINESS WIRE)–Breaking Brad: Cures, Unfiltered is a new podcast born from biotech founder Bradley Burnam’s journey as a patient-turned-CEO. A superbug survivor and founder of Turn Therapeutics, Burnam blends lessons from building a company with candid conversations featuring trailblazers reshaping medicine.

“I came to biotech as an outsider, desperate for a cure that didn’t exist,” said Burnam, who hosts Breaking Brad. “I learned to navigate the FDA, raise capital, and build a company — but also saw how much promising science gets stuck because health policies have not kept up with innovation. This podcast is about sharing those lessons and spotlighting others pushing boundaries in healthcare.”

After contracting a drug-resistant infection, Burnam developed his own cure, carried it through FDA clearance on his own, and built Turn Therapeutics into a company with multiple FDA-cleared products. That dual perspective — patient and founder — shapes Breaking Brad to make complex science and policy accessible while asking why so many cures remain out of reach.

Season one has begun streaming on YouTube, Spotify, and Apple, with episodes highlighting breakthroughs in stem cells, ethnobotany, and functional medicine. Guests include world-renowned stem cell therapy pioneer Neil Riordan, Ph.D.; leading ethnobotanist Cassandra Quave, Ph.D.; Vanderbilt University’s infectious disease expert Buddy Creech, M.D.; and functional medicine leader Greer McGuinness. The season also confronts major healthcare topics like autism, drug pricing, and women’s health.

“What began as me trying to understand the system for my own survival has become a mission to move that same system forward,” Burnam added. “This podcast is about sharing what I’ve learned — and giving a platform to others who are doing work the world needs but rarely sees.”

For more information or to request an interview with Turn Therapeutics CEO and Breaking Brad host Bradley Burnam, please contact Ellie Pickel at (202) 816-4555 or ellie@keybridge.biz. For advertising inquiries: advertising@breakingbradshow.com.

About Follow Up Media

Follow Up Media is a full-service production, distribution, and marketing agency dedicated to helping brands create, launch, and scale content across every platform. From high-quality podcast studios and video storytelling to sonic branding and AI-powered solutions, the firm brings creativity, technical excellence, and results-driven execution to every project. Under the leadership of Founder and CEO Khristian Lee, Follow Up Media’s team of award-winning producers, engineers, and creatives transforms ideas into engaging, impactful media.

Contacts

Media Contact:
Follow Up Media — Khristian Lee, CEO

Email: klee@manfuzed.com | Phone: 678-437-0645

Follow Up Media: https://followupmedia.com

Fresenius Leads New EASYGEN Consortium Aimed at Decentralizing CAR-T Cell Therapy and Improving Hospital Workflows




Fresenius Leads New EASYGEN Consortium Aimed at Decentralizing CAR-T Cell Therapy and Improving Hospital Workflows

• Physicians, researchers, and partner institutions across Europe aim to deliver innovative, personalized therapies more quickly
• Development project focused on a hospital-based modular platform, based on technology initially developed by Fresenius Kabi
• The EASYGEN project is a public-private partnership, with €8 million backed by EU funding through the Innovative Health Initiative
• Important step in #FutureFresenius program

BAD HOMBURG, Germany–(BUSINESS WIRE)–#CommittedToLife–The global healthcare company Fresenius is collaborating with other companies and academic institutions with the goals of accelerating the manufacturing of CAR-T cell therapy, making it more cost-effective, and improving patient access across Europe. Led by Fresenius, the newly launched EASYGEN (Easy workflow integration for gene therapy) consortium will focus on efforts to develop a modular, hospital-based platform capable of manufacturing personalized cell therapies in just a few days, rather than weeks. The project is a public-private partnership, with €8 million in funding provided by the EU through the Innovative Health Initiative (IHI). It leverages technology originally developed by the Cell and Gene Therapy team of Fresenius Kabi, part of Fresenius.

Dr. Christian Hauer, President MedTech at Fresenius Kabi, said: “This project contributes to expanding our MedTech platform, making it an important step on our path to #FutureFresenius. The aim is not only to develop cutting-edge medical technologies, but also to make them available quickly, safely, and close to the patient. In this way, we are actively working to shape the healthcare of tomorrow.”

“EASYGEN brings together physicians, researchers, and partner institutions from across Europe with the goal of collaboratively advancing innovative, personalized therapies such as CAR-T cells for cancer treatment. Automation can help reduce production complexity of these therapies, with the aim of making it easier to scale these life-saving treatments and improve patient access,” added Prof. Dr. med. Ralf Kuhlen, Chief Medical Officer at Fresenius.

CAR-T therapy is a breakthrough treatment that involves genetically modifying a patient’s T cells to target cancer. It requires complex, time-intensive production in specialized facilities often far from patients. Limited manufacturing capacity and supply chain delays can potentially prevent timely patient access. Despite clinical eligibility, access to CAR-T cell therapy remains limited for patients across Europe. This is particularly evident in diffuse large B-cell lymphoma (LBCL), a type of cancer that is one of the most common indications: Across five European countries, the average treatment rate is below 20%. While approximately 30% of eligible patients receive CAR-T therapy in France, the figure drops to just 11% in Italy.¹

Fresenius is actively involved in cell and gene therapy. Fresenius Kabi provides medical technology for these therapies, including automated cell processing systems such as Lovo and Cue. Fresenius Helios, for example, at its Helios Hospital Berlin-Buch, has been offering CAR-T cell therapy as a standard treatment for relapsed cases since 2019. The clinic is also conducting clinical trials to further explore the potential of CAR-T therapies. Quirónsalud, Fresenius’ Spanish hospital business, has established specialized oncology units that offer CAR-T cell therapy as part of their advanced cancer treatment portfolio, particularly for hematologic malignancies.

EASYGEN is led by Fresenius and academically co-led by Fraunhofer Institute, IZI, Leipzig – one of Europe’s foremost immunotherapy research centers in collaboration with Prof. Dr. Michael Hudecek, a leader in CAR-T cell engineering and Prof. Dr. Ulrike Köhl, a pioneer in translational cellular immunotherapies.

Consortium partners – 18 organizations across 8 countries

Industry & clinical leaders: Fresenius (Coordinator, Germany), Helios Hospital Berlin-Buch (Germany), Quirónsalud (Spain), Fenwal Inc. (USA), Cellix Ltd. (Ireland), Charles River (Germany), Pro-Liance Global Solutions (Germany), TQ Therapeutics (Germany), Philips Electronics Nederland B.V. (Netherlands).

Academic & research institutions: Fraunhofer IESE (Germany), Fraunhofer IZI (Germany), Helmholtz-Zentrum Dresden-Rossendorf (Germany), Technical University of Denmark (Denmark), Frankfurt School of Finance & Management (Germany), European Society for Blood & Marrow Transplantation (Netherlands), Bar-Ilan University (Israel), University of Glasgow (UK), University of Navarra (Spain).

Learn more about CAR-T cell therapy: Interview Prof. Bertram Glaß, Chief Physician for Hematology and Cell Therapy at Helios Hospital Berlin-Buch: https://www.fresenius.com/car-t-cell-therapy

About Fresenius

Fresenius SE & Co. KGaA (Frankfurt/Xetra: FRE) is a global healthcare company headquartered in Bad Homburg v. d. Höhe, Germany. In the 2024 fiscal year, Fresenius generated €21.5 billion in annual revenue. Fresenius currently counts over 176,000 employees. The Fresenius Group comprises the operating companies Fresenius Kabi and Fresenius Helios as well as an investment in Fresenius Medical Care. With around 140 hospitals and countless outpatient facilities, Fresenius Helios is the leading private hospital operator in Germany and Spain, treating around 26 million patients every year. Fresenius Kabi’s product portfolio touches the lives of 450 million patients annually and includes a range of highly complex biopharmaceuticals, clinical nutrition, medical technology, and intravenous generic drugs and fluids. Fresenius was established in 1912 by the Frankfurt pharmacist Dr. Eduard Fresenius. After his death, Else Kröner took over management of the company in 1952. She laid the foundations for a global enterprise that today pursues the goal of improving people’s health. The largest shareholder is the non-profit Else Kröner-Fresenius Foundation, which is dedicated to advancing medical research and supporting humanitarian projects.

For more information visit the Company’s website at http://www.fresenius.com

Follow us on social media: http://www.fresenius.com/socialmedia

About EASYGEN

EASYGEN is a five-year research project supported by the Innovative Health Initiative Joint Undertaking (IHI JU) under grant agreement No 101194710. The JU receives support from the European Union’s Horizon Europe research and innovation programme and COCIR, EFPIA, Europa Bío, MedTech Europe, Vaccines Europe and industry partners. Selected under the IHI call “User-centric technologies and optimized hospital workflows for a sustainable healthcare workforce,” the project aims to develop an integrated, automated platform that enables point-of-care CAR-T cell manufacturing—cutting production time, reducing costs, and expanding access to next-generation immunotherapies.

Disclaimer: Funded by the European Union, the private members, and those contributing partners of the IHI JU. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the aforementioned parties. Neither of the aforementioned parties can be held responsible for them.

Contacts

Press Contact
Timo Lindemann

Corporate Communications

Fresenius SE & Co. KGaA

Else-Kröner-Straße 1

61352 Bad Homburg

Germany

T +49 (0) 151 15515324

timo.lindemann@fresenius.com
www.fresenius.com

ICUS Urges CMS to Update CEUS Reimbursement, Citing Clinical Benefits for Patients and Healthcare Systems




ICUS Urges CMS to Update CEUS Reimbursement, Citing Clinical Benefits for Patients and Healthcare Systems

CHICAGO–(BUSINESS WIRE)–#CEUS–The International Contrast Ultrasound Society (ICUS) today urged the Centers for Medicare and Medicaid Services (CMS) to update reimbursement for certain contrast-enhanced ultrasound (CEUS) imaging procedures, citing important clinical benefits for patients and healthcare systems.

“CEUS is a safe, cost-effective, noninvasive, radiation-free imaging modality” that often reduces the need for downstream testing and procedures, speeds up diagnosis, lowers overall imaging costs, streamlines workflows, improves patient outcomes and save lives – even in the sickest patients, according to a letter submitted to CMS by the ICUS Board of Directors.

The letter asks CMS to reassign CPT Code 76978 and CPT Code 76979, both covering non-cardiac CEUS scans, to APC 5572 (Level 2 Imaging with Contrast). ICUS is not seeking a change in reimbursement for cardiac CEUS.

CEUS is used worldwide to assess blood flow in real time, allowing physicians to pinpoint and characterize tumors throughout the body, stratify a patient’s risk of heart attack and stroke, monitor chronic gastro-intestinal diseases and other serious medical conditions, and evaluate whether cancer and other therapies are working.

CEUS utilizes commercially available ultrasound contrast agents (UCAs) that are administered intravenously during an ultrasound exam. UCAs do not contain iodine or gadolinium and are not nephrotoxic.

“UCAs are among the safest of all contrast media,” ICUS said.

“CEUS offers a dynamic and highly reliable method of imaging all soft tissue tumors in the abdomen and pelvis, in real time – with sensitivity and specificity comparable to and sometimes better than contrast-enhanced CT and MRI,” said Dr. Richard G. Barr, a professor of radiology at Northeast Ohio Medical University and an officer of ICUS. Dr. Barr also is editor-in-chief of the Journal of Ultrasound in Medicine.

ICUS stated that contrast-enhanced CT and MRI procedures are already signed to APC 5572, so reassignment of CEUS would establish “clinical coherency that does not exist under the current APC assignment for CPT 76978.”

ICUS said it is seeking updated coding for non-cardiac CEUS in order to align reimbursement with the proven clinical and economic benefits.

“Unfortunately, despite the very successful and widespread use of CEUS outside the United States, under-reimbursement in the United States may impede the appropriate use of CEUS, as described in clinical guidelines, potentially to the detriment of patients,” according to Dr. Andrej Lyshchik, a professor of radiology at Thomas Jefferson University in Philadelphia. Dr. Lyshchik currently chairs the ACR LI-RADS CEUS Working Group and is a member of both the LI-RADS Steering Committee and the board of directors of ICUS.

According to Dr. Barr, CEUS allows physicians to identify, characterize and stage tumors of the liver, kidney, prostate, breast and other organ systems.

He said CEUS may be the only advanced imaging tool suitable for patients with renal failure when contrast enhanced CT or MRI cannot be used. And, CEUS may be an ideal option for pregnant patients because UCAs do not cross the placental barrier and because CEUS avoids exposure to ionizing radiation and iodinated contrast.

CEUS can also improve clinical workflows and avoid delays associated with CT and MRI, in part because ultrasound systems are more readily available in many medical centers.

“CEUS offers almost immediate results, so patients can get a speedy diagnosis and quicker access to appropriate therapy,” said Dr. Yuko Kono, a clinical professor of hepatology and radiology at University of California, San Diego and member of the ICUS Board.

ICUS is a non-profit medical society focused on the safe and appropriate utilization of CEUS where medically indicated in order to improve patient care and outcomes. ICUS members include radiologists, oncologists, hepatologists, cardiologists and other physicians, nurses, sonographers and ultrasound imaging professionals.

ICUS offers free membership and free CME-accredited educational webinars and resources, all accessible on the organization’s website: www.ICUS-Society.Org.

ABOUT ICUS:

The International Contrast Ultrasound Society (ICUS) is a nonprofit medical society dedicated to advancing the safe and medically appropriate use of contrast enhanced ultrasound (CEUS) to improve patient care globally. Membership in ICUS is free of charge and there is no fee for ICUS educational programs, CME credits, newsletters or other resources.

To join ICUS and learn more about CEUS, visit www.icus-society.org and download ICUS CONNECT, the free ICUS mobile app.

Contacts

International Contrast Ultrasound Society
Linda Maiman Feinstein, Advisor — 847-624-1844 or 312-876-2563, Linda.Feinstein@Dentons.com
Robin J. Adams, Director of Communication — 202-408-3946, Robin.Adams@Dentons.com

New Declaration from Carenet Health Urges Healthcare Leaders to Address Unsustainable Costs Stalling Business and Care Outcomes




New Declaration from Carenet Health Urges Healthcare Leaders to Address Unsustainable Costs Stalling Business and Care Outcomes

SAN ANTONIO–(BUSINESS WIRE)–#FutureOfHealthcare–As healthcare organizations contend with rising financial pressures, widespread burnout, and declining patient trust, Carenet has issued an industry call to action urging leaders to confront the hidden costs holding healthcare back.

The “Healthcare Costs Too Much to Ignore” declaration identifies five major categories of costs, beyond the obvious financial ones—operational waste, workforce burnout, eroded trust, declining care quality, and technology misalignment—as critical barriers to progress. The call to action comes amid mounting evidence that these burdens are unsustainable:

• $1 trillion in annual waste, by some estimates
• Nearly 1 in 5 clinicians considering exit due to burnout
• A healthcare system that spends twice as much as peer countries, amounting to nearly $15k per person per year and 18% of our GDP, yet delivers worse outcomes

“The U.S. has the greatest healthcare in the world, but the costs of delivering it are too great to ignore – and they aren’t just financial anymore,” said John Erwin, CEO and Founder of Carenet. “They’re human. Operational. Reputational. And they’re directly impacting growth, retention, and the ability to deliver better care. This declaration is an invitation for leaders to step back, reassess the real impact of complexity, and start building smarter, more sustainable systems.”

The declaration offers a framework to help organizations identify root causes of drag and redirect resources toward scalable, high-impact change. Focus areas include:

• Moving beyond surface-level cost containment to unlock long-term strategic value
• Strategically aligning technology, talent, and operations to reduce friction and drive efficiency
• Recognizing how system breakdowns erode trust among patients and employees
• Pinpointing the right areas to apply AI, automation and other innovations to optimize experiences and lower costs
• Creating cross-functional momentum around sustainable, enterprise-wide improvements

Carenet shared this point of view as part of its Powering Change campaign—an initiative designed to help healthcare leaders rethink performance through the lens of engagement, efficiency, and outcomes.

The full document is available for download here.

Join Carenet and this movement to Power Change at the HLTH conference in Las Vegas, Oct. 19-22. Carenet is an AI Pavilion sponsor and partnering with healthcare leaders to orchestrate AI to transform healthcare experiences.

About Carenet Health

Carenet Health is a tech-enabled healthcare services company dedicated to co-creating value with payers, providers, and health technology partners. For over 20 years, Carenet has combined advanced technology, data insights, clinical expertise, and global talent to improve engagement, efficiency, and meaningful business and health outcomes. To learn more about how Carenet is Powering the Business of Healthcare, visit carenethealth.com.

Contacts

Media Contact:
Skip Dampier, PR and Thought Leader

sdampier@carenethealth.com
214-356-9091

Lumaegis Secures $200,000 in Pre-Seed Funding to Accelerate FDA De Novo Certification—Propelling Its Breakthrough Sterilization Technology Toward Market Readiness




Lumaegis Secures $200,000 in Pre-Seed Funding to Accelerate FDA De Novo Certification—Propelling Its Breakthrough Sterilization Technology Toward Market Readiness

AUSTIN, Texas–(BUSINESS WIRE)–Lumaegis, Inc., an emerging leader in medical device innovation, was recently honored as one of the 2024 RadLaunch Challenge Winners by the International Ultraviolet Association, recognizing its groundbreaking contributions to solid-state lighting-based sterilization technologies.

Lumaegis has also successfully closed a $200,000 pre-seed funding round, led by one of their global strategic partners. Lumaegis will use these funds to build the next set of production units and conduct FDA, UL/CE, and longevity testing.

At the heart of Lumaegis’ innovation is the RadBox, a patent-protected sterilization device designed as a fast, energy-efficient alternative to traditional sterilizers. The RadBox has received FDA De Novo classification, a designation reserved for breakthrough technologies with no existing, approved predicate device. This status highlights the RadBox’s significant advantages and its potential to improve patient outcomes, all the while saving the practitioners tens of thousands of dollars per year.

The company is set to begin FDA-required testing later this year. The RadBox utilizes dual-modality approach i.e., combination of germicidal and thermal radiation emitted by Light Emitting Diodes to achieve sterility. With key patent already granted and additional applications nearing completion, Lumaegis is preparing for commercial launch upon FDA De Novo approval.

“We anticipate our first sales in 2026,” said CEO John S. Morreale. “Production will begin that year, and we already have customers lined up. Many dental professionals who collaborated with us during the RadBox design phase will be among our first users, providing essential clinical feedback. Additionally, we’ve secured our first major customer — a global industry partner and investor in the disinfection and sterilization space — representing over 2,000 units in initial sales.”

Lumaegis is poised to redefine sterilization standards across dental and medical practices, offering a transformative solution that combines speed, efficiency, and safety, all the while reducing practitioners’ costs and improving their productivity.

About:

Lumaegis is headquartered in Austin, TX and is a member of University of Texas’ Austin Technology Incubator. Its mission is to support global health security and to reduce the environmental impact of sterilization processes globally. The founders are seasoned serial entrepreneurs with a proven track record of leveraging technology to address sustainability challenges.

Contacts

John S. Morreale

sterilize@lumaegis.com

Northwell Study Finds Frequent Seizures, Mental Health History Predicts Epilepsy Drug Resistance




Northwell Study Finds Frequent Seizures, Mental Health History Predicts Epilepsy Drug Resistance

The findings are published in The Journal of the American Medical Association

MANHASSET, N.Y.–(BUSINESS WIRE)–While drugs are often prescribed for the 65 million people worldwide living with epilepsy, many patients are resistant to these drugs, making it paramount for clinicians to identify epileptic risks and triggers because experiencing uncontrolled seizures can lead to injuries, accidents and even death. A new study, published today in Journal of the American Medical Association (JAMA) by Northwell Health clinicians and researchers, found that people with newly diagnosed epilepsy who have pre-existing psychological disorders and frequent seizures have a lesser chance of successfully treating their epilepsy within a year.

The study, co-led by Ruben Kuzniecky, MD, a neurologist at Northwell’s Lenox Hill Hospital in Manhattan and member of The Feinstein Institutes for Medical Research, stems from the Human Epilepsy Project (HEP), a large-scale, international observational study that followed 448 participants for up to six years with newly diagnosed focal epilepsy. Focal epilepsy, also known as partial epilepsy, refers to a condition in which seizures originate from a specific, localized area of the brain and can manifest in various ways depending on the affected brain region, ranging from subtle changes in awareness to more noticeable motor symptoms. The study used standardized International League Against Epilepsy (ILAE) definitions for seizure freedom and treatment resistance, providing a rigorous framework for assessing outcomes.

“This study underscores the complex journey faced by individuals and their doctors to identify and treat focal epilepsy,” said Dr. Kuzniecky, professor and vice chair of academic affairs at The Barbara and Donald Zucker School of Medicine at Hofstra/Northwell. “While most patients eventually achieve complete absence of seizures, the path is often lengthy and requires trying different medications. Our findings emphasize the need for improved strategies for predicting and managing treatment response to avoid cognitive decline and improve quality of life.”

Key findings of the study include:

• Delayed seizure freedom: Median time to first seizure freedom was 12.1 months, highlighting the extended period during which many patients experience ongoing seizures.
• Treatment failure: Only 27 percent of participants achieved seizure freedom on their first anti-seizure medications (ASMs), underscoring the need for readily accessible second-line options.
• Treatment resistance: Nearly a quarter of participants were deemed treatment-resistant, meaning they did not achieve seizure freedom after trying two adequate ASM clinical trials. This group often had more frequent seizures at the beginning of the study and half of them became resistant within the first year.
• Psychiatric comorbidities: A history of psychiatric disorders prior to epilepsy diagnosis significantly increased the risk of treatment resistance, emphasizing the importance of holistic care for individuals with epilepsy.
• Challenging outcomes: Participants (23 percent) fell into an “indeterminate” category due to insufficient follow-up time or inadequate ASM clinical trials. This highlights the challenges in conducting long-term epilepsy research and the need for strategies to improve patient retention and standardize treatment protocols.

“This research reveals key scientific insights into why some focal epilepsy patients respond to treatment better than others,” said Kevin J. Tracey, MD, president and CEO of the Feinstein Institutes and Karches Family Distinguished Chair in Medical Research. “This knowledge is critical for developing more personalized and effective treatment strategies.”

The study suggests that earlier identification of treatment failure and personalized treatment strategies based on individual risk factors, including psychiatric comorbidities, are crucial for improving the lives of people living with focal epilepsy.

About the Feinstein Institutes

The Feinstein Institutes for Medical Research is the home of the research institutes of Northwell Health, the largest health care provider and private employer in New York State. Encompassing 50+ research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its six institutes of behavioral science, bioelectronic medicine, cancer, health system science, molecular medicine, and translational research. We are the global scientific leader in bioelectronic medicine – an innovative field of science that has the potential to revolutionize medicine. The Feinstein Institutes publishes two open-access, international peer-reviewed journals Molecular Medicine and Bioelectronic Medicine. Through the Elmezzi Graduate School of Molecular Medicine, we offer an accelerated PhD program. For more information about how we produce knowledge to cure disease, visit http://feinstein.northwell.edu and follow us on LinkedIn.

Contacts

Julianne Mosher Allen

516-880-4824

jmosherallen@northwell.edu

Brightseed’s 2025 Consumer Research Finds 45% of U.S. Adults Are Now “Bioactivists” – the Largest and Fastest-Growing Health Segment — Up from 27% in 2022




Brightseed’s 2025 Consumer Research Finds 45% of U.S. Adults Are Now “Bioactivists” – the Largest and Fastest-Growing Health Segment — Up from 27% in 2022

Latest research shows that this mainstream segment is 20% more likely to keep up with the latest health trends and 25% more willing to pay more for foods, beverages, and supplements containing bioactives compared to other segments

SAN FRANCISCO–(BUSINESS WIRE)–Brightseed, the bioactives leader unlocking nature with AI to elevate human health and developer of the Forager® AI platform, today announced findings from its second installment of Bioactivist consumer research. The updated findings revealed that 45% of U.S. adults now identify as Bioactivists – proactive, health-conscious consumers who see health as a foundation rather than a fix, and who are increasingly seeking products with proven health benefits. This is a sharp rise from 27% in Brightseed’s 2022 survey, making Bioactivists the fastest growing and largest health-focused consumer segment in the U.S. Access Brightseed’s infographic detailing the survey findings here.

KEY FINDINGS

• Bioactivists now represent 45% of U.S. adults
• High purchasing power & loyalty: Bioactivists skew toward higher incomes and are more likely to be repeat buyers when their health needs are met.
• Proactive health focus:
  • 87% use supplements; 43% use them consistently.
  • 68% regularly check nutrition labels.
  • +20% more likely to follow the latest health trends vs. other consumers.
  • +16% more likely to seek products with added nutrients.
• Bioactive-driven purchasing:
  • +25% more willing to pay more for foods, beverages, and supplements containing bioactives.
  • +14% more likely to try a new product because it contains bioactives.
  • +12% more interested in increasing bioactive intake.
• Health mindset: Bioactivists view health as a foundation, not a fix, and are motivated by long-term goals like avoiding future illness, living longer, and maintaining a healthy lifestyle.
• Market opportunity: More than 60% of consumers want brands to improve product healthfulness, communicate bioactive content, and back claims with science.

Bioactivists outpace other consumers in their commitment to health, with 87% incorporating supplements into their routines, 68% regularly checking nutrition labels, and strong interest in products with bioactives – naturally occurring compounds in plants and other sources that positively impact human health.

These consumers not only represent a large share of the U.S. population, they also hold significant purchasing power, skew toward higher incomes, and are brand-loyal when their health needs are met.

“The Bioactivist is no longer a niche wellness enthusiast – they’re your neighbor, your coworker, and a powerful driver of market trends,” said David Blackwood, SVP, Commercial at Brightseed. “For food, beverage, and health companies, this is a prime opportunity to engage a large, motivated, and high-spend audience that is actively seeking products with proven functional benefits.”

The research also found growing consumer expectations for transparency and science in health products. More than 60% of consumers agree that their favorite brands should improve product healthfulness, communicate bioactive content, and back claims with science.

Brightseed’s proprietary AI platform, Forager – an advanced discovery and development engine for small molecules and bioactives – is uniquely positioned to meet this demand.

“Bioactives are nature’s health drivers, and Forager allows us to discover and unlock them at an unprecedented scale, providing our partners market disrupting innovation and development tools,” said Sofia Elizondo, Co-Founder and President of Brightseed. “This research confirms that consumers are ready – and eager – for products that harness bioactives to support human health.”

The 2025 Brightseed Health & Nutrition Survey was conducted online in April 2025 among a nationally representative sample of 1,200 U.S. adults, ages 18 and older.

About Brightseed

Brightseed®, the bioactives leader unlocking nature with AI to elevate human health, is a World Economic Global Innovator. Brightseed’s proprietary AI, Forager®, accelerates bioactive discovery, biological validation, and ingredient formulation from years to months, rapidly revealing new connections between nature and humanity. Brightseed produces clinically-proven bioactives for dietary supplements, food & beverage CPG, specialty nutrition, and medical foods to power proactive health worldwide. Learn more at brightseedbio.com.

Contacts

Media Contact
Nicki Briggs, MS, RDN

Communications, Brightseed

press@brightseedbio.com

Chrislaina Anderson Awarded 2025 Adam Ferrari Health Science Scholarship




Chrislaina Anderson Awarded 2025 Adam Ferrari Health Science Scholarship

Chrislaina Anderson is proudly announced as the winner of the 2025 Adam Ferrari Health Science Scholarship, a $20K award honoring future healthcare leaders dedicated to compassionate care.

IRVINE, Calif.–(BUSINESS WIRE)–The Ferrari Foundation has named Chrislaina Anderson as the recipient of the 2025 Adam Ferrari Health Science Scholarship. This $20,000 award, established by Phoenix Energy CEO Adam Ferrari, recognizes exceptional health science students dedicated to enhancing care for individuals with physical disabilities.

Anderson was chosen from a competitive pool of applicants nationwide and impressed the selection committee with her academic excellence and dedication to service. Throughout the process, she demonstrated a clear vision for integrating bioengineering, medicine, and compassion to restore mobility, dignity, and independence for patients.

“Winning this scholarship is more than financial aid—it shows that people believe in me and my dreams,” Anderson shared. “When I found out I was selected, I was ecstatic. I immediately started yelling for my family to let them know the good news. This scholarship allows me to pursue a B.S. in Bioengineering at UC Berkeley, where I will have amazing opportunities to research medical devices and other healthcare-related technologies. It reassures me that I am ready for this big leap to make an impact within the medical community. I would like to thank everyone who made this possible.”

Anderson’s passion for healthcare is deeply personal. Growing up with a father and an aunt living with neuropathy, she witnessed firsthand how physical disability can affect not only mobility but also pride and independence. These experiences inspired her to pursue bioengineering as a way to design solutions that improve the quality of life for individuals with physical disabilities.

Anderson co-founded Hands Across Horizons, a nonprofit that provides educational resources to underserved students and trafficking survivors, and created Hands on Music, a free program for Title I children, including those with fine motor challenges. She has served as a class president, drum major, and tutor in over 20 college-level subjects—all while graduating as valedictorian with 129 college credits and earning an Associate’s Degree in Mathematics and Sciences at just 15 years old.

“Chrislaina’s academic accomplishments are extraordinary, but it is her empathy and commitment to designing healthcare solutions that truly stand out,” said Adam Ferrari, founder of the Ferrari Foundation. “Her mission to merge engineering with direct patient care reflects the core values that inspired this scholarship and carries forward the values shaped by my father’s experience.”

Now in its fifth year, the Adam Ferrari Health Science Scholarship continues to empower future healthcare leaders who combine academic excellence with a commitment to compassionate, patient-centered care. The award is presented annually to a student whose achievements and aspirations align with the Ferrari Foundation’s mission to advance accessibility, innovation, and high-quality care for individuals with physical disabilities.

For more information about the Adam Ferrari Health Science Scholarship, visit www.adamferrarischolarship.com.

Contacts

Caroline Scroggins

The Ferrari Foundation

949-526-8611

info@theferrarifoundation.org
https://www.theferrarifoundation.org/