M1 Kliniken AG: Completion of the Sale of 100% Subsidiary HAEMATO Pharm GmbH to PHOENIX group

M1 Kliniken AG

/ Key word(s): Disposal/Investment

M1 Kliniken AG: Completion of the Sale of 100% Subsidiary HAEMATO Pharm GmbH to PHOENIX group

02.02.2026 / 08:30 CET/CEST

The issuer is solely responsible for the content of this announcement.


M1 Kliniken AG: Completion of the Sale of 100% Subsidiary HAEMATO Pharm GmbH to PHOENIX group

Berlin, February 02, 2026 – M1 Kliniken AG (ISIN: DE000A0STSQ8) announces that the sale of HAEMATO Pharm GmbH by its majority holding, HAEMATO AG (85%), to the PHOENIX group was successfully completed effective as of the end of January 31, 2026.

Following the fulfillment of all closing conditions, including the necessary antitrust approvals, the transaction has now been legally consummated. Consequently, HAEMATO Pharm GmbH will be deconsolidated from the scope of consolidation of both HAEMATO AG and M1 Kliniken AG.

With the successful closing of this transaction, M1 Kliniken AG continues to consistently pursue its strategic focus and strengthens its positioning as a leading global, vertically integrated pure-play provider of medical aesthetics.

 

 

About M1 Kliniken AG

M1 Kliniken AG is the leading fully integrated provider of medical aesthetic services in Europe and Australia. With a clear strategic focus, high standardization, and consistent scalability, the Group currently operates 58 clinics in ten countries under the M1 Med Beauty brand. All treatments are performed exclusively by qualified physicians and adhere to uniform, high medical standards, while being offered at market-leading prices. Since late 2018, M1 has systematically driven its international expansion, which forms the basis for scalable future growth and the further development of its global market position. With the M1 Schlossklinik in Berlin, the Group operates one of Europe’s largest and most modern clinics for plastic and aesthetic surgery, featuring four operating theaters and 35 beds.

 

Contact:
M1 Kliniken AG
Grünauer Straße 5
12557 Berlin
T: +49 (0)30 347 47 44 14
M: ir@m1-kliniken.de


02.02.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: M1 Kliniken AG
Grünauer Straße 5
12557 Berlin
Germany
Phone: +49 (0)30 347 47 44 14
Fax: +49 (0)30 347 47 44 17
E-mail: ir@m1-kliniken.de
Internet: https://www.m1-kliniken.de
ISIN: DE000A0STSQ8
WKN: A0STSQ
Listed: Regulated Unofficial Market in Dusseldorf, Frankfurt (Basic Board), Hamburg, Hanover, Munich, Stuttgart, Tradegate BSX
EQS News ID: 2269298

 
End of News EQS News Service

2269298  02.02.2026 CET/CEST

Further growth in the fourth quarter leads to annual sales of EUR 12.5 million (+2%); Important milestone achieved in antibacterial implants

aap Implantate AG

/ Key word(s): Development of Sales

Further growth in the fourth quarter leads to annual sales of EUR 12.5 million (+2%); Important milestone achieved in antibacterial implants

02.02.2026 / 10:00 CET/CEST

The issuer is solely responsible for the content of this announcement.


 

  • Continued organic growth despite challenging comparative basis
  • APAC region strongest growth driver
  • Diversification contributes to stability and scalability
  • Human clinical trials successfully completed, scientific visibility will increase

 

aap Implantate AG (“aap”) reports preliminary sales growth of 2% year-on-year for the financial year, thus confirming stable business performance with positive momentum in the fourth quarter. The main growth drivers were once again the Asian markets.

The sales decline of around 3% in the first half of 2025 – due to one-off major orders in the first half of 2024 – was fully compensated for in the further course of the year. In the second half of the year, aap achieved an increase in sales of 8% compared to the same period of the previous year. Most of the sales regions contributed to this development with improved performance in the second half of the year.

In Germany, sales increased by 5% despite persistently challenging market conditions, underlining the company’s solid market position in its home market. In the United States, the shortfall of –9% in local currency recorded in the first half of the year was gradually made up, resulting in a slight increase of 1% for the year.

The APAC region developed particularly strongly, with aap achieving significant revenue growth of 98% for the full year with existing and new customers, consolidating Asia’s role as an increasingly important growth driver for the company.

Sales FY/2025

in EUR thousand FY/2025 FY/2024 Change
Trauma
EMEA (=Europe, Middle East, Africa)
North America
LATAM (= Latin America)
APAC (=Asia-Pacific)
 
6.269
2.767
2.490
   924
 
6.329
2.874
2.534
   466
 
%
-4%
-2%
98%
Revenue 12.450 12.203 2%

 

Region / Revenue in $ FY/2025 FY/2024 Change
North America 3.133 3.107 1%

 

In addition, the company made decisive progress in product development in the past fiscal year: The clinical human study on the innovative, antibacterial treated implants was successfully completed with excellent results. The complete study report is currently at the participating study centers for final approval.

The results are planned to be published in an internationally renowned journal later this year. This would further underpin the scientific relevance of technology and significantly increase its visibility in the global professional environment.

At the same time, the company is working with high priority on the approval of the new implants – both for the European market under the Medical Device Regulation (MDR) and for the US market under the regulations of the Food and Drug Administration (FDA). With the completion of these procedures, the company is creating the future basis for the global market launch of its exclusive “Silver Trauma Line” and the basis for licenses in other implant areas such as hip implants and others.

This step represents an important milestone and paves the way for the strategic development of the company into a new, international growth scenario.

The Company will provide information on the outlook for the 2026 financial year and the management agenda in a separate announcement.

The sales figures contained in this press release are preliminary figures as of December 31, 2025, and are subject to change until the final publication. aap plans to announce the final, audited results for the 2025 financial year at the end of April 2026 as part of the 2025 consolidated annual financial report.

 

——————————————————————————————————————————————-

aap Implantate AG (ISIN DE0005066609) – General Standard/Regulated Market – All German Stock Exchanges –

 

 

About aap Implantate AG

aap Implantate AG is a global medical technology company headquartered in Berlin, Germany. The company develops manufactures and markets products for traumatology. In addition to the innovative anatomical plate system LOQTEQ®, the IP-protected portfolio includes a wide range of perforated screws. In addition, aap Implantate AG has an innovative pipeline with promising development projects, such as antibacterial silver coating technology. This technology addresses critical and not yet adequately solved problems of Surgical Site Infections (SSI) in traumatology and applicable in other MedTech areas.  In Germany, aap Implantate AG sells its products directly to hospitals, purchasing groups and affiliated clinics, while on an international level, it primarily uses a broad network of distributors in around 41 countries. In the USA, the company and its subsidiary aap Implants Inc. rely on a distribution agent and selective direct sales strategy. The shares of aap Implantate AG are listed in the General Standard of the Frankfurt Stock Exchange (XETRA: AAQ.DE). For more information, please visit our website at www.aap.de.

There may be technical rounding differences in the figures presented in this press release, which do not affect the overall statement.

 

Forward-Looking Statements

This release may contain forward-looking statements based on the current expectations, assumptions and forecasts of the Management Board and information currently available to it. The forward-looking statements are not to be understood as guarantees of future developments and results referred to therein. Various known and unknown risks, uncertainties and other factors could cause the actual results, financial condition, development or performance of the Company to differ materially from the estimates given herein. These factors also include those described by aap in published reports. Forward-looking statements therefore speak only as of the date on which they are made. We undertake no obligation to update the forward-looking statements made in this release or to conform them to future events or developments.

 

If you have any questions, please contact: aap Implantate AG; Rubino Di Girolamo; Chairman of the Board of Directors/CEO; Lorenzweg 5; 12099 Berlin
Tel.: +49 (0)30 75019 – 141; Fax: +49 (0)30 75019 – 170; E-Mail: r.digirolamo@aap.de


02.02.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: aap Implantate AG
Lorenzweg 5
12099 Berlin
Germany
Phone: +49 (0) 30 75 019-0
Fax: +49 (0) 30 75 019-111
E-mail: info@aap.de
Internet: www.aap.de
ISIN: DE000A3H2101
WKN: A3H210
Listed: Regulated Market in Frankfurt (General Standard); Regulated Unofficial Market in Dusseldorf, Hamburg, Munich, Stuttgart, Tradegate BSX
EQS News ID: 2269250

 
End of News EQS News Service

2269250  02.02.2026 CET/CEST

Affluent Medical officially becomes CARVOLIX

Carvolix

/ Key word(s): Mergers & Acquisitions

Affluent Medical officially becomes CARVOLIX

02.02.2026 / 07:30 CET/CEST

The issuer is solely responsible for the content of this announcement.


Affluent Medical officially becomes CARVOLIX

Completion of the acquisitions of CARANX MEDICAL and ARTEDRONE

10m€ first tranche of financing completed

Aix-en-Provence, February 2, 2026 – 7:30 a.m. CET – Carvolix (formerly Affluent Medical) (ISIN: FR0013333077 – Ticker: AFME – “Carvolix” or the “Company”), a French commercial and clinical-stage medical technology company specializing in the international development and industrialization of breakthrough AI-driven mini-robots and biomimetic implants, to revolutionize interventional cardiology and the treatment of brain stroke is today announcing the completion of the acquisitions of Caranx Medical and Artedrone (the “Acquisitions”), for a closing price paid in Carvolix shares, to form a new, integrated MedTech company named Carvolix, as well as the definitive terms of the capital increases and the issuance of new shares (the “Financing” and, together with the Acquisitions, the “Transaction”) pursuant to the use of the delegations granted by the general meeting held on January 30, 2026 (the “General Meeting”).

A 10M€ first tranche of Financing has been made available by funds managed by Truffle Capital and by Edwards Lifesciences at a subscription price of €2.34 per share (which represents a 18.8% premium versus the last closing share price).

This strategic consolidation is designed to create a company for the 21st century interventional cardiologist – leveraging world leading technology in AI driven autonomous mini-robots with a mission to democratize complex, life-saving procedures. The combined platforms position Carvolix to accelerate radical innovation, expand its addressable market, and drive long term value creation.

“We’re applying our proven business builder model — uniting the capabilities of Truffle-founded companies to de-risk development, accelerate innovation, generate synergies and unlock value for shareholders” said Philippe Pouletty, M.D., CEO of Truffle Capital, founder of several successful biotech and medtech companies (including Abivax, Vexim, Symetis and Affluent Medical).  He added: “We expect to make the cardiology catheterization lab as autonomous and efficient as an aircraft cockpit so that our radical innovations could potentially benefit to millions of patients worldwide.”

Carvolix will focus on revolutionizing cardiac valve replacement and brain stroke treatment, addressing major unmet medical needs in large markets with a total addressable value of €23 billion. Currently, only 17% of the 1.7 million patients annually eligible for Transcatheter Aortic Valve Implantation (TAVI) undergo the procedure, and only 5% of ischemic stroke patients (second cause of death, third cause of disability) receive mechanical thrombectomy. Similarly, just 4% of the four million patients with severe mitral valve regurgitation undergo surgery.

“We are bringing together three extremely innovative and synergistic MedTech companies into one – with the goal of augmenting the cardiac catheterization lab to treat far more patients suffering from valve dysfunction and brain stroke” said Sebastien Ladet, CEO of Carvolix. “In addition, we will boost synergies in R&D and commercialization between the three companies to enable the development and delivery of additional products, such as a robotically delivered mitral valve.”

The combination of these companies unites deep expertise and R&D synergies across micro-robotics, AI, image guidance and biomimetic  valve technologies — accelerating innovation and establishing a robust, sustained product development cadence.

The first product launch is occuring in early 2026, with the TAVIPILOT softwarealready cleared by the FDA, being introduced in the US.  The Company plans to keep direct commercialization rights in Europe and seek partners in the US, Middle East, and Asia.

“We are building a fantastic management team and board of directors to carry out our mission: a commercial stage MedTech leader dedicated to helping interventional cardiologists treat more patients around the worldsaid Liane Teplitsky, Executive Chair of the Board of Directors of Carvolix.

Completion of the Acquisitions

On December 19, 2025, the Company announced the upcoming acquisition of Caranx Medical and Artedrone, becoming Carvolix, pioneering cardiovascular therapies with AI driven autonomous mini-robots and innovative implants. On January 30, 2026, the Acquisitions have been formally completed and the consolidation of Caranx Medical and Artedrone with the pre-existing Affluent Medical entities into Carvolix is now effective.

The terms and conditions of the Acquisitions are further detailed in the Company press release dated December 19, 2025. In particular, Carvolix made closing payments of respectively €16.6M and €11.4M, entirely in Carvolix shares, for the acquisition of Caranx Medical and Artedrone. Carvolix also acquired from Truffle BioMedTech CrossOver FPCI a current account against Artedrone for an amount of €1M plus accrued interests (at a rate of 8% per annum) (the “Current Account”).

Truffle funds, acting as sellers in the context of the Acquisitions, entirely rolled-over the closing purchase price and the purchase price of the Current Account at a subscription price of €2.34 per ordinary share (i.e., the same price as for the Financing), resulting in the issuance of a total of 12,384,470 new ordinary shares.

These 12,384,470 new ordinary shares were issued by the Board of Directors on January 30, 2026 pursuant to the delegations granted by the general meeting of the Company held on January 30, 2026, for a total subscription price of €28,979,659.80 offset with the closing purchase price and the purchase price of the Current Account.

Initial Tranches of Financing

On December 19, 2025, the Company further announced the launch of a concomitant Financing of up to €30M led by Truffle Capital and Edwards Lifesciences who undertook to make available to the Company a first tranche of €10M (the “First Tranche”).  The Company will secure up to €300,000 from several business angels (the “Additional Tranche”, and together with the First Tranche, the “Initial Tranches”).

Following the adoption by shareholders of the appropriate resolutions at the General Meeting, the Board of Directors decided on January 30, 2026 to use the delegations granted by the General Meeting to proceed with the implementation of the Initial Tranches, consisting of 4,401,708 new ordinary shares at a subscription price of €2.34 per Financing Share (which represents a 18.8% premium versus the last closing share price).

The purpose of the Initial Tranches of the Financing is to extend the horizon of the Company’s cash position from December 2025 to the end of May 2026.

The Initial Tranches of the Financing will allow the Company to pursue clinical and regulatory development for all its devices, and to position itself favorably as it embarks on the next steps of value creation. These steps include, but are not limited to, launching the commercialization in the US of TAVIPILOT Software, negotiating a strategic agreement with an industrial player to speed up the clinical trials and marketing of Artus, progress towards first in human for the robotic platform for stroke treatment and continue the development and clinical activities of Epygon.

The allocation of the proceeds of the Initial Tranches between the different programs should be approximately as follows: 28% to TAVIpilot, 27% to Artus, 23% to structural heart devices (Kalios and Epygon), 22% to ARTE-DRONE.

The financing required to pursue the combined Carvolix activities over the next 12 months, according to current development plans, is estimated at around €26M, of which €10.3M is secured through the Initial Tranches of the Financing.

The Company expects to secure the remainder (i.e., an additional amount of €15.7M) from several international investors, with whom discussions are currently ongoing. The Company also expects to be able to further extend its cash runway through, among other things, the proceeds that would be generated from a potential partnership deal with regards to Artus, an artificial urinary sphincter currently in Carvolix’s product portfolio.

Conversion of the June 2025 convertible bonds

On June 20, 2025, the Company issued €5.4M in convertible bonds to some of its main historical shareholders (the “Convertible Bonds”). In accordance with their terms, the Convertible Bonds are immediately and automatically payable in connection with the implementation of the Financing.

Each bondholder has irrevocably undertaken to subscribe, by way of debt offset, to a capital increase concomitant to the First Tranche of the Financing, such that no cash reimbursement will be made in connection with the redemption of the Convertible Bonds. The ordinary shares issued in connection with the redemption of the Convertible Bonds are subscribed by the bondholders at a price of €1.872 per ordinary share (corresponding to a 20% discount).

Following the adoption by shareholders of the appropriate resolutions at the General Meeting, the Board of Directors decided on January 30, 2026 to use the delegations granted by the General Meeting to proceed with the redemption of the Convertible Bonds and the issuance of 3,107,305 ordinary shares (including 2,605,384 ordinary shares to be issued to Truffle Medeor FPCI) at a subscription price of €1.872 per ordinary share (which represents a 5% discount versus the last closing share price).

Impact of the Transaction on the share capital

Taking into account the share issues resulting from (i) the Roll-Over, (ii) the Initial Tranches of the Financing, and (iii) the redemption of the Convertible Bonds, the shareholding structure of the Company will be as follows:

Investors Pre-Operation Post- Consolidation Post-Equity Round (First Tranche: 10.3M€)
# Shares % Ownership #New Shares (Acquisition) #New Shares (ACC Conversion) # Shares % Ownership #New Shares (Investment) #New Shares (OC Conversion) # Shares % Ownership
Affluent Medical Historicals        39.350.192 100,0%                                    –                                           –        39.350.192 76,06%                                    –                   3.107.305        42.457.497 71,7%
Artedrone Historicals [1]                               –   0,0%                4.859.771                         436.248         5.296.019 10,24%                                    –               5.296.019 8,9%
Caranx Medical Historicals [1]                               –   0,0%                7.088.451                                         –           7.088.451 13,70%                                    –                                       –             7.088.451 12,0%
Investors in the new round [2]                               –   0,0%                                    –                                           –                               –   0,00%                4.401.708                                     –             4.401.708 7,4%
Total        39.350.192 100%             11.948.222                         436.248      51.734.662 100%                4.401.708                 3.107.305        59.243.675 100%
                     
Investors Pre-Operation Post- Consolidation Post-Equity Round (First Tranche: 10.3M€)
# Shares % Ownership #New Shares (Acquisition) #New Shares (ACC Conversion) # Shares % Ownership #New Shares (Investment) #New Shares (OC  Conversion) # Shares % Ownership
Truffle Capital        26.255.202 66,7%             11.948.222                         436.248      38.639.672 74,7%                2.136.751                 2.605.384        43.381.807 73,2%
      Truffle BMT          3.479.373 8,8%               7.207.581                        436.248     11.123.202 21,5%               1.495.726         12.618.928 21,3%
     Truffle  FRR               915.097 2,3%               1.188.239          2.103.336 4,1%              2.103.336 3,6%
     Truffle  MEDEOR       10.296.874 26,2%               3.552.402       13.849.276 26,8%                    641.025                2.605.384       17.095.685 28,9%
     Truffle Others       11.563.858 29,4%         11.563.858 22,4%           11.563.858 19,5%
Edwards           3.623.188 9,2%                                    –                                           –           3.623.188 7,0%                2.136.752                                     –             5.759.940 9,7%
Financière Memnon           3.746.240 9,5%                                    –                                           –           3.746.240 7,2%                                    –                        346.153           4.092.393 6,9%
Hayk Holding                200.000 0,5%                                    –                                           –                200.000 0,4%                           28.846               228.846 0,4%
Ginko invest                605.546 1,5%                                    –                                           –                605.546 1,2%                           69.230               674.776 1,1%
Founders, executives and members of the Board of Directors, the Advisory Board and committees                   14.920 0,0%                                    –                                           –                   14.920 0,0%                      14.920 0,0%
Public and others           4.905.096 12,5%                                    –                                           –           4.905.096 9,5%                                    –                           57.692           4.962.788 8,4%
New Investors [3]                               –   0,0%                                    –                                           –                               –   0,0%                     128.205                                     –                 128.205 0,2%
Total        39.350.192 100,0%             11.948.222                         436.248      51.734.662 100,0%                4.401.708                 3.107.305        59.243.675 100,0%
[1] Artedrone and Caranx are fully owned by funds managed by Truffle Capital                
[2] Third party investors + Edwards and funds managed by Truffle Capital participating to the new round (excluding conversions of Affluent Medical’s and Artedrone Convertible Bonds and current accounts)      
[3] New third party investors only (excluding funds managed by Truffle Capital & Edwards)              

The 19,893,483 shares issued will result in a dilution of 33.57% (on a non-diluted basis). Following such issuance, the Company’s share capital will amount to €5,924,367.50 divided into 59,243,675 shares with a nominal value of €0.10. A shareholder holding 1.00% of the Company’s share capital before the Transaction would therefore hold 0.66% of the capital after the completion of the Transaction.

As part of the Transaction, it is reminded that up to an additional 14,283,985 shares could be issued in connection with the payment of earn-outs for the acquisition of Caranx Medical and Artedrone as well as with the subsequent tranches of the Financing (assuming up to 20M€ in additional financing subscribed at a price of €2.34 per share), representing an additional dilution of 14% (on a non-diluted basis).

In accordance with applicable provisions of the French Commercial Code, each subscriber of ordinary shares has abstained from voting on the resolution related to the removal of shareholders’ preferential rights for its benefit at the General Meeting and, as the case may be, the representatives of the subscribers at the Board of Directors have abstained from participating to the relevant decisions of the Board of Directors.

Impact of the Transaction on the shareholders’ equity

The share of equity, based on the Company’s consolidated financial statements at June 30, 2025, would be as follows:

Total equity (consolidated equity at June 30, 2025 in thousands of euros) 21.110€
Share of equity before issuance of the 19,893,483 shares 0,54€
Share of equity after issuance of the 19,893,483 shares 1,08€

Governance

As previously announced, the Board has decided to appoint Mrs. Liane Teplitsky as Executive Chair of the Board of Directors in replacement of Mr. Michel Therin, who will continue to contribute to the Board as director, effective as from the date of closing of the Transaction.

Advisors

Dechert LLP acted as legal advisor to the Company in connection with the Transaction.

Settlement and Delivery – Documentation

The ordinary shares issued in connection with (i) the Roll-Over, (ii) the Initial Tranches of the Financing, and (iii) the redemption of the Convertible Bonds, are expected to be admitted to trading on Euronext on February 4, 2026.

Such ordinary shares will be subject to an application for admission to trading on Euronext on the same trading line as the existing ordinary shares of the Company currently listed on Euronext, under the same ISIN code FR0013333077.

The Transaction is not subject to a prospectus requiring approval by the Financial Markets Authority (the “AMF”). However, in accordance with Article 1.5.b bis of Regulation (EU) 2017/1129 of the European Parliament and of the Council of June 14, 2017, as amended (the “Prospectus Regulation”), the Company will file with the AMF a document containing the information required in Annex IX of the Prospectus Regulation (the “Information Document”), with a view to the admission to trading on the regulated market of Euronext in Paris (“Euronext Paris”) of the Shares to be issued in connection with the Transaction. The Information Document is not subject to a review by the AMF.

Risk factors

Members of the public should take note of the risk factors relating to Carvolix and its business, as presented in Chapter 3 of the 2024 Universal Registration Document filed with the AMF on April 30, 2025 under number D.25-0356, which is available free of charge on Carvolix’s website (www.affluentmedical.com). The occurrence of all or some of these risks would be likely to have an adverse effect on the business activity, financial position, results, development, or outlook of Carvolix. Such events could have a material adverse effect on Carvolix’s share price. Members of the public should particularly take note of the following risks:

  • Raising additional capital, including as a result of this Transaction or of further offerings to finance the development or the commercialization of Carvolix’s products, may cause dilution to the Company’s shareholders, restrict its operations or require it to relinquish rights to its products;
  • Future sales of ordinary shares by existing shareholders or investors participating in the Transaction could depress the market price of the Company’s shares;
  • The market price of the Company’s shares can be subject to significant fluctuations and may decrease below the issuance price retained in the context of the Transaction;
  • Volatility and liquidity of the shares of the Company can be subject to significant fluctuations;
  • The Company’s management will have broad discretion over the use of the proceeds from the Financing and may apply these proceeds in ways that may not result in an increase of the share price.

In particular, Carvolix has updated risk factor 3.4.1 “Liquidity risk” of the 2024 Universal Registration Document in order to take into account the Financing, as well as risk factor 3.4.3 “Dilution risk” of the 2024 Universal Registration Document (for more information about the dilution, please see the above capitalization table) to reflect that the exercise of all the dilutive instruments held by officers, directors and employees, the warrants issued to Kreos and the earn-outs granted in the context of the Acquisitions, would result in a dilution of 31% to existing shareholders on the basis of the Company’s current share capital.

This press release does not constitute a prospectus as referred to in Regulation (EU) 2017/1129 of the European Parliament and of the Council of June 14, 2017, as amended, or an offer to the public.

About Carvolix

Carvolix is a French medical technologies company, commercial and clinical stage, founded by Truffle Capital, that aims to become a global leader in the treatment of structural heart diseases and brain strokes, world’s leading causes of mortality and disability. Carvolix develops novel AI and imaging driven mini-robots that make complex procedures doble by interventional cardiologists, as well as biomimetics heart valves.

About Truffle Capital

Founded in 2001, Truffle Capital is an independent European Venture Capital firm specializing in disruptive technologies in the Life Sciences (Medtech and Biotech) and IT sectors (Fintech and Insurtech). Truffle Capital’s mission is to support the creation and development of innovative companies capable of becoming the leaders of tomorrow, and it has notably founded Abivax.

Managed by Philippe Pouletty, M.D. and Bernard-Louis Roques, Co-founders and co-CEOs, Truffle Capital manages €500 million in assets. It has raised more than €1.2 billion since its creation and has supported more than 124 companies in the digital technology and life sciences sectors. Discover more at www.truffle.com and follow us on LinkedIn.

Contacts :

CARVOLIX
 
Sébastien LADET
CEO
investor@carvolix.eu
SEITOSEI.ACTIFIN
Communication financière / relations presse financière
Ghislaine GASPARETTO / Enora BUDET
+33 (0)6 85 36 76 81 / +33 (0)6 72 17 84 60 
ghislaine.gasparetto@seitosei-actifin.com / enora.budet@seitosei-actifin.com 
PRIMATICE
Relations médias France
Thomas ROBOREL de CLIMENS
+33 (0)6 78 12 97 95
thomasdeclimens@primatice.com
MC SERVICES AG
Relations médias Europe
Maximilian SCHUR / Julia BITTNER
+49 (0)211 529252 20 / +49 (0)211 529252 28
affluent@mc-services.eu

Disclaimer

This press release contains forward-looking statements about Carvolix and its business. All statements other than statements of historical fact included in this press release, including, but not limited to, statements regarding Carvolix’s financial condition, business, strategies, plans and objectives for future operations are forward-looking statements. Carvolix believes that these forward-looking statements are based on reasonable assumptions. However, no assurance can be given that the expectations expressed in these forward-looking statements will be achieved. These forward-looking statements are subject to numerous risks and uncertainties, including those described in Chapter 3 of the 2024 Universal Registration Document filed with the AMF on April 30, 2025 under number D.25-0356, which is available on the Company’s website (www.affluentmedical.com), as well as the risks associated with changes in economic conditions, financial markets and the markets in which Carvolix operates. The forward-looking statements contained in this press release are also subject to risks that are unknown to Carvolix or that Carvolix does not currently consider material. The occurrence of some or all of these risks could cause the actual results, financial condition, performance or achievements of Carvolix to differ materially from those expressed in the forward-looking statements. This press release and the information contained herein do not constitute an offer to sell or subscribe for, or the solicitation of an order to buy or subscribe for, shares of Carvolix in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. The distribution of this press release may be restricted in certain jurisdictions by local law. Persons into whose possession this document comes are required to comply with all local regulations applicable to this document.

This press release does not constitute a prospectus within the meaning of Regulation (EU) 2017/1129 of the European Parliament and of the Council of 14 June 2017 (the “Prospectus Regulation“). With respect to the member states of the European Economic Area (each, a “Relevant Member State“), no offer of the securities mentioned herein is made or will be made to the public in that Relevant Member State, except (i) to any legal person who is a qualified investor as defined in the Prospectus Regulation, (ii) to fewer than 150 natural or legal persons per Relevant Member State, or (iii) in other circumstances falling within Article 1(4) of the Prospectus Regulation; provided that none of these offers shall require the publication by the Company of a prospectus pursuant to Article 3 of the Prospectus Regulation. For the purposes of the foregoing, the expression “offer to the public” in any Relevant Member State has the meaning given to it in Article 2(d) of the Prospectus Regulation.

Solely for the purposes of each manufacturer’s product approval process, the target market assessment in respect of the securities offered in the Financing has led to the conclusion that, in relation to the type of clients criteria, (i) the target market for the securities is eligible counterparties and professional clients, each as defined in Directive 2014/65/EU, as amended (“MiFID II“); and (ii) all channels for distribution of the securities offered in the Financing to eligible counterparties and professional clients are appropriate. Any person subsequently offering, selling or recommending the shares (a “distributor“) should take into consideration the manufacturers’ client type assessment; however, a distributor subject to MiFID II is responsible for undertaking its own target market assessment in respect of the shares offered in the Financing (by either adopting or refining the manufacturers’ target market assessment) and determining appropriate distribution channels.

This press release has been prepared in French, German, Arabic and English. In the event of any discrepancy between the four versions of the press release, the French version shall prevail.


02.02.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Carvolix
320 avenue Archimède – Les pléiades III Batiment B
13100 Aix-en-Provence
France
E-mail: affluent@mc-services.eu
Internet: www.affluentmedical.com
ISIN: FR0013333077
Listed: Regulated Unofficial Market in Dusseldorf, Frankfurt, Hanover, Munich, Stuttgart, Tradegate BSX; Paris
EQS News ID: 2269194

 
End of News EQS News Service

2269194  02.02.2026 CET/CEST

Test Headline 30.01.26

Basel, January 30, 2026 – Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet. Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

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Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

nctus est Lorem ipsum dolor sit amet. Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed 

nctus est Lorem ipsum dolor sit amet. Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. 

ABOUT SANDOZ
Sandoz (SIX: SDZ; OTCQX: SDZNY) is the global leader in affordable medicines, with a growth strategy driven by its Purpose: pioneering access for patients. More than 20,000 people of 100 nationalities work together to ensure 900 million patient treatments are provided by Sandoz, generating substantial global healthcare savings and an even larger social impact. Its leading portfolio of approximately 1,300 products addresses diseases from the common cold to cancer. Headquartered in Basel, Switzerland, Sandoz traces its heritage back to 1886. Its history of breakthroughs includes Calcium Sandoz in 1929, the world’s first oral penicillin in 1951, and the world’s first biosimilar in 2006. In 2024, Sandoz recorded net sales of USD 10.4 billion.

CONTACTS 1

Global Media Relations contacts

Investor Relations contacts

Global.MediaRelations@sandoz.com

Investor.Relations@sandoz.com

Alexis Kalomparis
+41 792 790285

Craig Marks

+44 7818 942 383

Chris Lewis

+49 174 244 9501

Tamara Hackl

+41 79 790 5217

Gregor Rodehueser

+49 170 574 3200

Silvia Siegfried

+41 79 795 9061

CONTACTS 2

Global Media Relations contacts

Investor Relations contacts

Global.MediaRelations@sandoz.com

Investor.Relations@sandoz.com

Alexis Kalomparis
+41 792 790285

Craig Marks
+44 7818 942 383

Chris Lewis
+49 174 244 9501

Tamara Hackl
+41 79 790 5217

Gregor Rodehueser
+49 170 574 3200

Silvia Siegfried
+41 79 795 9061

Test 2 Headline 30.01.26

Basel, January 30, 2026 – Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet. Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et justo duo dolores et ea rebum. Stet clita kasd gubergren, no sea takimata sanctus est Lorem ipsum dolor sit amet.

nctus est Lorem ipsum dolor sit amet. Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed 

nctus est Lorem ipsum dolor sit amet. Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. 

ABOUT SANDOZ
Sandoz (SIX: SDZ; OTCQX: SDZNY) is the global leader in affordable medicines, with a growth strategy driven by its Purpose: pioneering access for patients. More than 20,000 people of 100 nationalities work together to ensure 900 million patient treatments are provided by Sandoz, generating substantial global healthcare savings and an even larger social impact. Its leading portfolio of approximately 1,300 products addresses diseases from the common cold to cancer. Headquartered in Basel, Switzerland, Sandoz traces its heritage back to 1886. Its history of breakthroughs includes Calcium Sandoz in 1929, the world’s first oral penicillin in 1951, and the world’s first biosimilar in 2006. In 2024, Sandoz recorded net sales of USD 10.4 billion.

Heidelberg Pharma Received Development Milestone Payment from Partner Takeda

Heidelberg Pharma AG

/ Key word(s): Miscellaneous

Heidelberg Pharma Received Development Milestone Payment from Partner Takeda

29.01.2026 / 13:27 CET/CEST

The issuer is solely responsible for the content of this announcement.


PRESS RELEASE

Heidelberg Pharma Received Development Milestone Payment from Partner Takeda

Ladenburg, Germany, 29 January 2026 – Heidelberg Pharma AG (FSE: HPHA), a clinical stage biotech company developing innovative Antibody Drug Conjugates (ADCs), today announced that it has received a milestone payment under the terms of its license agreement with partner Takeda based on the achievement of a clinical development milestone for Takeda’s investigational medicine that utilizes Amanitin-based Antibody Drug Conjugate (ATAC) technology licensed from Heidelberg Pharma. With the dosing of the first patient in a Phase I/II clinical trial in patients with solid tumors, a milestone payment to Heidelberg Pharma became due. Financial details were not disclosed.

Dr. Dongzhou Jeffery Liu, Chief Executive Officer of Heidelberg Pharma AG, commented: “We are very delighted that our partner Takeda is progressing the development of their investigational medicine that utilizes ATAC technology, and that we have received the according milestone payment. We congratulate the Takeda team and wish them every success in clinical development. With this, three candidates that leverage ATAC technology are now in clinical development, two that are proprietary to Heidelberg Pharma including HDP-101 (INN: pamlectabart tismanitin) and HDP-102, and one under the responsibility of our partner. For us, this is a further validation of the potential of our unique Amanitin-based ADC technology.”

Takeda exclusively licensed the worldwide development and commercialization rights from Heidelberg Pharma for the use of the ATAC technology with an antibody directed to a defined target and the resulting product candidate. Under the terms of the agreement, Takeda is responsible for the development, as well as commercialization, of the resulting product candidate.

About Heidelberg Pharma

Heidelberg Pharma is a biopharmaceutical company working on a new treatment approach in oncology and developing novel drugs based on its ADC technologies for the targeted and highly effective treatment of cancer. ADCs are antibody-drug conjugates that combine the specificity of antibodies with the efficacy of toxins to fight cancer. Selected antibodies are loaded with cytotoxic compounds, that are transported into diseased cells. Inside the cells, the toxins then unleash their effect and kill the diseased cells.

Heidelberg Pharma is the first company to use the compound Amanitin from the green death cap mushroom in cancer therapy. The biological mechanism of action of the toxin represents a new therapeutic modality and is used as a compound in the Amanitin-based ADC technology, the so-called ATAC technology.

The lead candidate HDP-101 (INN: pamlectabart tismanitin) is a BCMA ATAC in clinical development for multiple myeloma. The candidate has been granted Orphan Drug Designation and Fast Track Designation from the FDA. A second ATAC candidate, HDP-102 is in clinical development stage in Non-Hodgkin Lymphoma. HDP-103 against metastatic castration-resistant prostate cancer and HDP-104 targeting gastrointestinal tumors such as colorectal cancer have completed preclinical development. Heidelberg Pharma is open for partnering.

The company is based in Ladenburg, Germany, and is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol HPHA. More information is available at www.heidelberg-pharma.com

ATAC® is a registered trademark of Heidelberg Pharma Research GmbH. 

Contact
Heidelberg Pharma AG
Sylvia Wimmer
Director Corporate Communications
Tel.: +49 89 41 31 38-29
E-Mail: investors@hdpharma.com
Gregor-Mendel-Str. 22, 68526 Ladenburg
 
IR/PR-Support
MC Services AG
Katja Arnold (CIRO)
Managing Director & Partner
Tel.: +49 89 210 228-40
E-Mail: katja.arnold@mc-services.eu
 

This communication contains certain forward-looking statements relating to the Company’s business, which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “will”, “should”, “future”, “potential” or similar expressions or by a general discussion of the Company’s strategy, plans or intentions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results of operations, financial condition, performance, achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors and partners are cautioned not to place undue reliance on such forward-looking statements. We disclaim any obligation to update any such forward-looking statements to reflect future events or developments.


29.01.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Heidelberg Pharma AG
Gregor-Mendel-Str. 22
68526 Ladenburg
Germany
Phone: +49 (0)89 41 31 38 – 0
Fax: +49 (0)89 41 31 38 – 99
E-mail: investors@hdpharma.com
Internet: www.heidelberg-pharma.com
ISIN: DE000A11QVV0
WKN: A11QVV
Listed: Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Dusseldorf, Munich, Stuttgart, Tradegate BSX
EQS News ID: 2268116

 
End of News EQS News Service

2268116  29.01.2026 CET/CEST

Eckert & Ziegler on Track as Planned and Achieves Another Record Year in 2025

Eckert & Ziegler SE

/ Key word(s): Preliminary Results

Eckert & Ziegler on Track as Planned and Achieves Another Record Year in 2025

29.01.2026 / 12:20 CET/CEST

The issuer is solely responsible for the content of this announcement.


Fiscal Year 2025 (preliminary):

  • Sales: approx. € 312 million (PY: € 295.8 million)
  • EBIT before special items: approx. € 78 million (PY: € 65.9 million)
  • Net income: approx. € 48 million (PY: € 33.3 million)

Berlin, 29 January 2026. According to preliminary, unaudited figures for the 2025 financial year, Eckert & Ziegler SE (ISIN DE0005659700, TecDAX) generated sales of around € 312 million and adjusted EBIT of around € 78 million. Sales are up around 5% on the previous year, while adjusted EBIT is up by around 18%. Net profit (from continuing and discontinued operations), which is only reported here for comparison purposes, rose to around € 48 million (previous year: € 33.3 million).

The forecast for the 2026 financial year will be published on 26 March 2026 together with the complete, audited annual financial statements for the 2025 financial year.

About Eckert & Ziegler.
Eckert & Ziegler SE with more than 1.000 employees is a leading specialist for isotope-related components in nuclear medicine and radiation therapy. The company offers a broad range of services and products for the radiopharmaceutical industry, from early development work to contract manufacturing and distribution. Eckert & Ziegler shares (ISIN DE0005659700) are listed in the TecDAX index of Deutsche Börse.
Contributing to saving lives.

Your contact:
Eckert & Ziegler SE, Karolin Riehle, Investor Relations
Robert-Rössle-Str. 10, 13125 Berlin, Germany
Tel.: +49 (0) 30 / 94 10 84-138, karolin.riehle@ezag.de, www.ezag.com 


29.01.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
The issuer is solely responsible for the content of this announcement.

The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.


Language: English
Company: Eckert & Ziegler SE
Robert-Rössle-Str.10
13125 Berlin
Germany
Phone: +49 30 941084-138
Fax: +49 30 941084-0
Internet: www.ezag.de
ISIN: DE0005659700
WKN: 565970
Indices: SDAX, TecDax,
Listed: Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Dusseldorf, Hamburg, Munich, Stuttgart, Tradegate BSX
EQS News ID: 2268106

 
End of News EQS News Service

2268106  29.01.2026 CET/CEST

Lonza Delivers Strong Profitable Growth in Full-Year 2025 and Successfully Completes Vacaville Site Integration

  • In 2025, Lonza1 delivered sales of CHF 6.5 billion with +21.7% CER2 growth, and a CORE EBITDA of CHF 2.1 billion at a margin of 31.6% (+1.4ppts versus prior year), outperforming its upgraded CDMO outlook for the year
  • The strong momentum in winning new business continued in 2025 across Technology Platforms and sites, including a fifth significant commercial contract for Vacaville
  • The new One Lonza operating model was successfully launched on 1 April 2025 and already brings benefits for customers and operational performance
  • The proposed dividend of CHF 5.00 per share represents an increase of +25% versus prior year
  • For 2026, Lonza anticipates CER sales growth of 11-12% and further CORE EBITDA margin expansion, reaching a level above 32%
  • Capsules & Health Ingredients (CHI) saw +3.9% CER growth in 2025 and CORE EBITDA margin improvement of +1.6ppts versus prior year to 25.9%.3 CHI reported as Discontinued Operations

Basel, Switzerland, 28 January 2026 – Lonzareported sales of CHF 6.5 billion in FY 2025, reflecting a CER sales growth of +21.7% (+19.2% AER4) compared to prior year. A CORE EBITDA of CHF 2.1 billion resulted in a strong margin of 31.6% (+1.4ppts versus prior year), supported by maturing growth projects, robust operational execution and operating leverage. Excluding the business related to the Vacaville site, organic CER sales growth was in the low-teens at an improved CORE EBITDA margin, in line with Lonza’s CDMO Organic Growth Model.5

Lonza’s sales in 2025 benefited from robust momentum in the Mammalian, Bioconjugates, Small Molecules, Drug Product and Bioscience Technology Platforms, and was further supported by a higher than expected contribution of the Vacaville site. This was partially offset by a softer performance in Cell & Gene (CG) and phasing in Microbial.

Strategic, Operational and Organizational Progress in 2025

2025 was a year of significant progress for Lonza. On 1 April 2025, the company successfully implemented its new simplified and streamlined operating model, designed to deploy the new One Lonza strategy through three aligned Business Platforms (Integrated Biologics, Advanced Synthesis, Specialized Modalities) and strengthened crossplatform Group Functions, especially in Operations and Quality. The organizational changes were executed seamlessly and are already improving ways of working, reflected in the strongly supportive feedback from Lonza’s leadership community in Voice of Employee surveys.

The establishment of a groupwide Strategic Enterprise Account Management team further strengthened customer proximity, reflected in a significant uplift in Lonzas already industryleading net promoter score versus prior year. The newly formed team for corporate strategy, innovation and M&A is focused on driving value creation as a pureplay CDMO through organic and inorganic growth across current and future Technology Platforms. In parallel to these efforts, Lonza has continued to advance the CHI carveout and exit process as planned.

Overall, the ongoing transformation will further elevate Lonza’s ability to deliver a seamless customer experience at high service levels across all Business Platforms, improve manufacturing productivity, and efficiently execute growth projects in all key regions globally. This will ensure consistent, longterm profitable growth in line with Lonzas CDMO Organic Growth Model.

Business Highlights in 2025

Business highlights in 2025 included strong order momentum across Technology Platforms and sites. This included an increasing number of integrated drug substance-drug product agreements for clinical and commercial programs. Continuing strong customer interest in the Vacaville large-scale mammalian drug substance facility is evidenced by a fifth significant commercial contract and further contracts in late-stage negotiations. The Vacaville site is now fully integrated into Lonzas global manufacturing network, including a seamless postmerger integration, the first successful technical transfer of a new commercial product, the first successful US FDA audit under Lonza ownership, the first investments in operational flexibility well underway, and substantial new business already contractually secured.

With CHF 1.3 billion of CapEx in 2025 (19.6% of sales), Lonza made significant progress in executing its ongoing organic investment program to enable future growth across technologies, while gradually reducing its CapEx intensity. Strategic growth projects across Mammalian, Drug Product, Bioconjugates and CG progressed well and will provide the capacities and capabilities needed to drive long-term value creation, strengthening Lonza’s global CDMO market leadership.

The CHI business delivered on its Outlook 2025 with CER sales growth of +3.9% versus prior year, returning to a robust +8.0% CER sales growth in H2 2025. The CORE EBITDA margin improved by +1.6ppts to 25.9% in FY 2025. Going forward, recent final affirmative determinations in US antidumping and countervailing investigations are expected to restore competitive balance to the benefit of future growth and margins. Following a well-executed carveout process, CHI as a Discontinued Operation delivered +4.4% CER growth at a CORE EBITDA margin of 24.7%.

Sustainability and Governance

Lonza is on track to achieve its 2023 science-based near-term sustainability targets, including its commitment to reduce absolute Scope 1 and 2 greenhouse gas (GHG) emissions by 42% by 2030.6 In 2025, the company achieved reductions of more than 50% in both GHG and waste intensity against the 2018 base year, surpassing both 2030 targets ahead of plan. Lonza continued to expand renewable sourcing across all key regions. As of January 2026, all electricity purchased across the US, Europe and China is now from renewable sources.

In October 2025, Lonza’s Board of Directors announced the nomination of Claudia Süssmuth-Dyckerhoff as an Independent Member and Vice-Chair of the Board of Directors, subject to her election at the AGM in May 2026. Claudia brings a wealth of international experience in healthcare and life sciences, and an outstanding track record of board memberships in publicly listed companies.

Lonza’s Board of Directors will propose to increase the dividend by +25% to CHF 5.00 per share at the Lonza AGM in May 2026. Subject to approval, 50% of the dividend will be paid out of the capital contribution reserve, meaning it will be exempt from Swiss withholding tax.

Wolfgang Wienand, CEO, Lonza, commented: “2025 was a strong year for the One Lonza team, marked by significant revenue growth with expanding profitability alongside tangible progress on our transformation journey. We executed our existing business with rigor and, at the same time, continued to lay the foundations for future growth. In the face of geopolitical and economic volatility, Lonza’s business model, once again, proved resilient and delivered on the promise to effectively diversify risks across the broadest technology offering, commercial portfolio and global manufacturing footprint in the CDMO industry. Based on what we achieved together in 2025, we are well positioned to continue executing our strategy in 2026 and beyond – for the benefit of our customers and their patients, our shareholders and our people.”

Outlook 2026

For 2026, Lonza anticipates a continued strong performance in line with its CDMO Organic Growth Model and expects CER sales growth of 11-12% and further CORE EBITDA margin expansion, reaching a level above 32% of sales. CER sales growth is expected to be stronger in the first half of 2026 than in the second half.

Lonza anticipates an FX7 headwind of approximately -2.0% on sales and CORE EBITDA in 2026, mainly from the full-year effect of the weakening of the US Dollar in 2025, assuming spot rates of mid-January 2026 prevail throughout the year. With a robust natural hedge and Lonza’s financial hedging program, margins will be minimally impacted.

Given recent geopolitical and geoeconomic shifts toward more regional supply chains and its extensive and welldiversified global manufacturing network across key regions and technologies, Lonza is well positioned to support customers seeking to align regional supply with regional demand. Looking ahead, Lonza plans to further expand its asset base, leveraging its strong track record of building, acquiring, and operating assets worldwide. The highquality, largescale capacities in Vacaville, together with the expertise of its local team, significantly strengthens Lonzas global mammalian offering. As the largest biologics CDMO in the US, Lonza is uniquely positioned to support customers looking to align US supply with US demand.

The significant investment announcements of large pharmaceutical companies are likely to be primarily shifts in global CapEx spend toward the US, while biotech companies continue to have a limited focus on in-house capacities. The strong economic rationale to outsource to CDMOs remains unchanged for large pharma and biotech companies to enable economically efficient global pharmaceutical supply.

In the evolving geopolitical and geoeconomic landscape, Lonza expects no material financial impact from currently published US trade and tariff policies but continues to monitor the situation closely.

For its CHI business in 2026, Lonza expects mid-single-digit percentage CER sales growth and further CORE EBITDA margin expansion.

Business Platform Overview for 2025: Continuing Business

  • Integrated Biologics reported strong CER sales growth of +32.2% versus prior year, driven by sustained demand for its large-, mid-, and small-scale assets, supported by maturing growth projects and the Vacaville site acquisition, which generated around CHF 0.6 billion sales. The CORE EBITDA margin reached 35.3% (-0.9ppts versus prior year) with good operational execution almost offsetting the dilution from growth projects and unfavorable portfolio mix effects.
  • Advanced Synthesis reported exceptionally strong CER sales growth of +22.4% versus prior year, supported by rapid and simultaneous ramp-up of recently added growth projects in Small Molecules and Bioconjugates. Good operational execution, efficient growth project ramp-ups and operating leverage led to a CORE EBITDA margin of 41.8% in FY 2025 (+5.2ppts versus prior year).
  • Specialized Modalities reported a CER sales decline of -3.0%versus prior year, impacted by a softer operational performance in CG and phasing in Microbial. Compared to a weaker H1 2025, the business showed improving trends with H2 returning to growth, especially in Microbial, while CG remained subdued. Bioscience reported robust CER sales growth throughout the year. The Platform’s CORE EBITDA margin remained almost unchanged at 17.0% (-0.5ppts versus prior year), driven by favorable portfolio mix effects and cost discipline.
 

Group Financial Summary for 2025: Continuing Business

CHF million

 

FY 2025

 

YoY change (in %)

 

FY 2024

Sales in AER

 

6,531

 

+19.2

 

5,480

Growth in CER in %

 

+21.7

 

+20.4ppts

 

+1.3

CORE EBITDA

 

2,064

 

+24.9

 

1,653

    Margin in %

 

31.6

 

+1.4ppts

 

30.2

EBITDA

 

1,970

 

+35.7

 

1,452

    Margin in %

 

30.2

 

+3.7ppts

 

26.5

EBIT

 

1,239

 

+36.5

 

908

    Margin in %

 

19.0

 

+2.4ppts

 

16.6

For more details, please refer to the Full-Year 2025 Presentation, Full-Year 2025 Report and Alternative Performance Measures (APM) 2025 Report.


Financial information presented for “Lonza” reflects Lonza’s continuing CDMO business.
2 Constant Exchange Rates (CER).
3 Excluding costs directly attributable to Discontinued Operations. See page 41 of the FY 2025 presentation for a bridge to Discontinued Operations.
4 Actual Exchange Rates (AER).
5 Low-teens organic CER sales growth on average over time and CORE EBITDA growth ahead of sales growth.
6 Against the 2021 base year.
7 Foreign Exchange.

MHH to Present Scientific Findings on Cold Plasma Therapy for Pulmonary Application at Press Conference in February 2026

Viromed Medical AG

/ Key word(s): Miscellaneous

MHH to Present Scientific Findings on Cold Plasma Therapy for Pulmonary Application at Press Conference in February 2026

27.01.2026 / 16:43 CET/CEST

The issuer is solely responsible for the content of this announcement.


PRESS RELEASE

MHH to Present Scientific Findings on Cold Plasma Therapy for Pulmonary Application at Press Conference in February 2026

Rellingen, 27 January 2026 – On 12 February 2026, Hannover Medical School (MHH) – represented by Prof. Dr. Hortense Slevogt – plans to hold a press conference together with the team from the Helmholtz Centre for Infection Research (HZI) in Braunschweig.

The focus of the event will be the presentation and scientific classification of a groundbreaking cold plasma therapy for application in the lungs. For Viromed stakeholders, the findings are of high strategic relevance, as they address a medical field in which there is an urgent and, to date, insufficiently met clinical need worldwide: severe pulmonary infections – particularly in vulnerable patient groups and in intensive care settings.

The relevance of the topic is driven in particular by three key factors:

  • High global disease burden: Pulmonary infections and associated complications affect millions of patients worldwide every year and represent one of the major challenges of modern acute and intensive care medicine.
  • Growing therapeutic limitations: The increasing prevalence of antibiotic-resistant pathogens further exacerbates the situation and intensifies the pressure to develop new and effective therapeutic approaches.
  • New physical treatment option: The planned publication of an innovative physical therapy principle for the lungs potentially represents a paradigm shift in infection treatment and opens up the prospect of scalable clinical application.

 

About Viromed Medical AG

Viromed Medical AG specializes in the development, manufacture and distribution of medical products. The operating business of the company, which has been listed on the stock exchange since October 2022, focuses on the distribution of innovative cold plasma technology for medical applications via its wholly owned subsidiary Viromed Medical GmbH. Viromed can draw on a broad customer base in the DACH region and beyond. Viromed is pursuing the goal of further advancing the use of cold plasma technology in medicine in the coming years and realizing the corresponding growth potential.

www.viromed-medical-ag.de

Contact Viromed

E-Mail: kontakt@viromed-medical.de
 

Press contact

E-mail: viromed@kirchhoff.de


27.01.2026 CET/CEST Dissemination of a Corporate News, transmitted by EQS News – a service of EQS Group.
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Language: English
Company: Viromed Medical AG
Hauptstraße 105
25462 Rellingen
Germany
E-mail: kontakt@viromed-medical.de
Internet: https://www.viromed-medical-ag.de/
ISIN: DE000A40ZVN7
WKN: A40ZVN
Listed: Regulated Unofficial Market in Dusseldorf, Frankfurt, Hamburg, Tradegate BSX
EQS News ID: 2266836

 
End of News EQS News Service

2266836  27.01.2026 CET/CEST

Siegfried to acquire high-quality small molecules drug substance capacity in the US

Media Release
Zofingen, January 27, 2026

Ad hoc announcement pursuant to Art. 53 Listing Rules

Siegfried (SIX: SFZN), a leading global Contract Development and Manufacturing Organization (CDMO) for the pharmaceutical industry, has signed binding agreements with an affiliate of SK Capital Partners to acquire the drug substance business of the Noramco Group and Extractas Bioscience. The acquired businesses include three high-quality small molecules drug substances sites with approximately 400 employees:

  • Noramco, a large, commercial-scale manufacturing site in Wilmington, Delaware (US)
  • Purisys, a clinical API development and manufacturing facility located in Athens, Georgia (US)
  • Extractas Bioscience, a leading manufacturer of purified products based in Westbury, Tasmania (AU)

The acquisition marks another important milestone in the execution of Siegfried’s EVOLVE+ strategy, expanding the company’s presence and capacity in the US, the world’s largest pharmaceutical market.

Siegfried plans to expand its fast-growing exclusive synthesis business in the US by optimizing its controlled substance capacity across the newly acquired Wilmington site and its nearby Pennsville site. Combined with the early-phase development capabilities of Purisys and the extraction expertise of Extractas Bioscience, the acquisition strengthens Siegfried’s integrated offering to its customers and provides a strong foundation for accelerating growth and improving profitability.

Marcel Imwinkelried, Chief Executive Officer: “This transaction marks a decisive next step in the execution of our EVOLVE+ strategy and is aligned with our highly selective, disciplined value accretive approach to M&A. By adding exceptional US-based capabilities, we will become even more attractive to both existing and new customers, creating new opportunities to accelerate profitable growth. The combined capacity and expertise of the three sites strengthen our position as a leading CDMO for small-molecule drug substances, and I look forward to fully realizing this value together with our new colleagues.”  

The valuation of the acquired business is below 10 times Enterprise Value / EBITDA. Given Siegfried’s strong balance sheet, the acquisition will be financed through existing and new debt instruments. Subject to customary closing conditions, the transaction is expected to close later this year.