Click4tag is a French biotech company developing an innovative technique to rapidly detect and concentrate cultivable Gram-negative bacteria.
Click4tag – detecting pathogenic bacteria
Rapidly detecting the presence of pathogenic bacteria is essential in a number of sectors, such as the food or cosmetics industries. To guarantee the absence of these bacteria, it is necessary to block batches for 24 to 48 hours before they are put on the market, which can be a handicap. Click4tag is now proposing a new technique to rapidly detect and concentrate cultivable Gram-negative bacteria. This innovative process will enable the release of commercial batches within a day. The approach developed by Click4Tag consists in specifically functionalizing the membrane of microorganisms of interest via the natural assimilation and then the integration of a « hook » onto this membrane. Afterwards, this anchorpoint allows, via a « click » reaction, to associate classical tags such as a fluorescent probe (to detect, enumerate and identify microorganisms of interest), or magnetic beads (in order to concentrate and isolate specifically microorganisms of interest). According to the choice of probe, it is possible to obtain a specific detection. For example, Gram negative bacteria are « revealed » by the assimilation of a 3-deoxy-D-manno-octulosonic acid derivative. Nowadays, Click4tag’s probe library is composed of 2 molecules, one targeting Gram negative bacteria and the other one targeting specifically the bacterium L. pneumophila.
Click4tag is a biotech company based in Marseille (France). Co-founders are Sam Dukan and Boris Vauzeilles, and Scientific board is composed by Philippe Cornet, Yves Lévi and Jean-Yves Guedj.
More about Click4tag : www.click4tag.com