Oculis Publishes 2025 Consolidated Financial Statements




Oculis Publishes 2025 Consolidated Financial Statements

ZUG, Switzerland, March 05, 2026 (GLOBE NEWSWIRE) — Following the Company‘s press release published on March 3, the audited consolidated financial statements for the financial year 2025 and the MD&A, which have now been filed with the SEC on form 20-F, are attached.

Attachments

• Oculis 2025 Consolidated IFRS Financial Statements
• Oculis 2025 MD&A
• Oculis ESEF reporting

Oculis to Participate in Upcoming Investor Conferences




Oculis to Participate in Upcoming Investor Conferences

ZUG, Switzerland, March 05, 2026 (GLOBE NEWSWIRE) — Oculis Holding AG (Nasdaq: OCS; XICE: OCS) (“Oculis” or the “Company”), a global biopharmaceutical company focused on innovations addressing ophthalmic and neuro-ophthalmic diseases with significant unmet medical needs, announced today that Oculis’ management will participate in upcoming investor conferences in March.

Oculis is pleased to present updates of its innovative, highly differentiated, late-stage portfolio as it enters a pivotal phase in its transformation into a leader in neuro-ophthalmology and ophthalmology. Key highlights include: Privosegtor (PIONEER program) granted breakthrough therapy designation for optic neuritis (ON) as Oculis advances the registrational program in two optic neuropathies to address a potential market opportunity of $7B+ in the U.S. alone; OCS-01 (DIAMOND Phase 3 trials) topline results in diabetic macular edema (DME) on track for Q2 2026; Licaminlimab (PREDICT-1 registrational trial) being evaluated as the first genotype-based development program to drive precision medicine in dry eye disease (DED).

With a strong balance sheet and robust pipeline, Oculis is well-positioned to deliver 6 pivotal readouts with the current funding, to fulfil its mission to save sight and improve eye care with groundbreaking treatments.

Leerink Global Healthcare Conference
March 8-11, Miami, FL, USA
Company presentation by Riad Sherif, M.D., Chief Executive Officer, on March 10^th, 10:40 AM ET.
Webcast link: Register here

Leerink Partners Mountain Meeting
March 22-25, Jackson Hole, WY, USA
Oculis management will participate in one-on-one meetings.

LifeSci Capital Biotech Forum
March 26, New York City, NY, USA
Oculis management will participate in one-on-one meetings.

The company will be available for one-on-one meetings during the conferences. Interested investors should contact their respective representative at the sponsoring institutions to request meetings.

Webcast links, when available, are posted to the Oculis website on the Events & Presentation page under the Investors & Media section.

About Oculis

Oculis is a global biopharmaceutical company (Nasdaq: OCS; XICE: OCS) focused on breakthrough innovations to address significant unmet medical needs in neuro-ophthalmology and ophthalmology. Oculis’ highly differentiated late-stage clinical pipeline includes three core product candidates: Privosegtor, a breakthrough neuroprotective candidate in the PIONEER program which consists of studies intended to support registration plans for treatment in optic neuropathies like optic neuritis (ON) and non-arteritic anterior ischemic optic neuropathy (NAION), with potentially broad clinical applications in various other neuro-ophthalmic and neurological diseases; OCS-01, an eye drop in pivotal registration studies, aiming to become the first non-invasive topical treatment for diabetic macular edema (DME); and Licaminlimab, a novel, topical anti-TNFα in registrational trial, which is being developed with a genotype-based approach to drive precision medicine in dry eye disease (DED). Headquartered in Switzerland with operations in the U.S. and Iceland, Oculis is led by an experienced management team with a successful track record and supported by leading international healthcare investors. For more information, please visit: www.oculis.com

Oculis Contacts
Ms. Sylvia Cheung, CFO
sylvia.cheung@oculis.com

Investor Relations
LifeSci Advisors
Corey Davis, Ph.D.
cdavis@lifesciadvisors.com

Media Relations
ICR Healthcare
Amber Fennell / David Daley / Sean Leous
oculis@icrhealthcare.com

Cautionary Statement Regarding Forward Looking Statements

This press release contains forward-looking statements and information. For example, statements regarding the development plans for Privosegtor, OCS-01, and Licaminlimab; the initiation, timing, progress and results of clinical trials of Privosegtor, OCS-01, and Licaminlimab; and Oculis’ research and development programs, regulatory and business strategy, future development plans, and management, are forward-looking. All forward-looking statements are based on estimates and assumptions that, while considered reasonable by Oculis and its management, are inherently uncertain and are inherently subject to risks, variability, and contingencies, many of which are beyond Oculis’ control. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as, and must not be relied on by an investor as, a guarantee, assurance, prediction or definitive statement of a fact or probability. Actual events and circumstances are difficult or impossible to predict and will differ from assumptions. All forward-looking statements are subject to risks, uncertainties and other factors that may cause actual results to differ materially from those that we expected and/or those expressed or implied by such forward-looking statements. Forward-looking statements are subject to numerous conditions, many of which are beyond the control of Oculis, including those set forth in the Risk Factors section of Oculis’ annual report on Form 20-F and any other documents filed with the U.S. Securities and Exchange Commission (SEC). Copies of these documents are available on the SEC’s website, www.sec.gov. Oculis undertakes no obligation to update these statements for revisions or changes after the date of this release, except as required by law.

Press Release:  Sanofi’s Board of Directors proposes the appointment of Christel Heydemann as an independent director




Press Release:  Sanofi’s Board of Directors proposes the appointment of Christel Heydemann as an independent director

Sanofi’s Board of Directors proposes the appointment of Christel Heydemann as an independent director 

Paris, March 5, 2026. The Board of Directors of Sanofi has decided to propose, at the next Annual General Meeting of shareholders scheduled for April 29, 2026, the appointment of Christel Heydemann as an independent director, as well as the renewal of the mandates of Christophe Babule and Jean-Paul Kress. 

Patrick Kron, independent director and Chairman of the Nomination, Governance and CSR Committee, will step down from the Board at the end of his term, which will expire at the upcoming Annual General Meeting on April 29. The Board warmly thanks Patrick Kron for his decisive contribution to its work over the past 12 years, particularly with respect to key governance decisions. 

Christel Heydemann has been Chief Executive Officer of the Orange Group since April 2022, after serving as a member of the Board of Directors from July 2017. She began her career at Alcatel in 1999, where she held various management positions, including during the merger between Alcatel and Lucent. In 2008, she was appointed Chief Commercial Officer for France and joined the Executive Committee of Alcatel-Lucent France. In 2011, she headed up Human Resources and Transformation for the group. In 2014, Christel Heydemann joined Schneider Electric. In 2017, she was appointed Chairman and Chief Executive Officer of Schneider Electric France. In 2021, she took on the role of Executive Vice President, Europe Operations. A graduate of École Polytechnique and École Nationale des Ponts et Chaussées, Christel Heydemann is actively committed to promoting diversity and innovation, particularly in encouraging women to pursue careers in science and technology. Christel Heydemann is an Officer of the French National Order of Merit and a Knight of the French Legion of Honor.  

“We sincerely thank Patrick Kron for the commitment and rigor he has brought to the Board’s work over the past twelve years, both as a director and in the various committee chair roles he has held. The proposed appointment of Christel Heydemann reflects the Board’s determination to further strengthen the diversity of expertise and backgrounds within our governance,” said Frédéric Oudéa, Chairman of the Board of Directors of Sanofi. “Her recognized experience leading major international groups, her expertise in industrial and digital transformation, and her strategic vision will be valuable assets in supporting Sanofi through the next phase of its development.” 

With these appointments and the arrival of Belén Garijo as Chief Executive Officer and director, the Board would remain composed of 16 members, including two employee representatives, gender parity (57% of women excluding employee representatives).  

The composition of the Board’s specialized committees will be reviewed following the Annual General Meeting scheduled for April 29, 2026.  

About Sanofi  
Sanofi is an R&D driven, AI-powered biopharma company committed to improving people’s lives and creating compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time. Sanofi is listed on EURONEXT: SAN and NASDAQ: SNY 

Media Relations 
Sandrine Guendoul | +33 6 25 09 14 25 | sandrine.guendoul@sanofi.com  
Evan Berland | +1 215 432 0234 | evan.berland@sanofi.com   
Léo Le Bourhis | +33 6 75 06 43 81 | leo.lebourhis@sanofi.com   
Victor Rouault | +1 617 356 4751 | victor.rouault@sanofi.com  
Timothy Gilbert | +1 516 521 2929 | timothy.gilbert@sanofi.com  
Léa Ubaldi | +33 6 30 19 66 46 | lea.ubaldi@sanofi.com 
Ekaterina Pesheva | + 1 410 926 6780 ekaterina.pesheva@sanofi.com  

Investor Relations 
Thomas Kudsk Larsen | +44 7545 513 693 | thomas.larsen@sanofi.com   
Alizé Kaisserian | +33 6 47 04 12 11 | alize.kaisserian@sanofi.com  
Keita Browne | +1 781 249 1766 | keita.browne@sanofi.com  
Nathalie Pham | +33 7 85 93 30 17 | nathalie.pham@sanofi.com  
Thibaud Châtelet | +33 6 80 80 89 90 | thibaud.chatelet@sanofi.com  
Yun Li | +33 6 84 00 90 72 | yun.li3@sanofi.com 

Attachment

• Press Release

Nxera Pharma to Receive US$3 Million Milestone Payment from Centessa Pharmaceuticals




Nxera Pharma to Receive US$3 Million Milestone Payment from Centessa Pharmaceuticals

Tokyo, Japan and Cambridge, UK, 5 March 2026 – Nxera Pharma Co., Ltd. (“Nxera” or “the Company”; TSE 4565) today announces that Centessa Pharmaceuticals has achieved an additional early development milestone associated with its investigational, orally administered, highly potent and selective orexin receptor 2 (OX2R) agonist, ORX489, being developed by Centessa for the treatment of neuropsychiatric disorders. This milestone triggers a payment of US$3 million to Nxera pursuant to its research collaboration with Centessa. The milestone payment will be recognized as revenue in the first quarter of 2026.

–END–

About Nxera Pharma
Nxera Pharma is a technology powered biopharma company in pursuit of new specialty medicines to improve the lives of patients with unmet needs in Japan and globally. The Company has built an agile, new-generation commercial business in Japan to develop and commercialize innovative medicines, including several launched products, to address this high-value, large and growing market and those in the broader APAC region. In addition, the Company is advancing an extensive pipeline internally and in partnership with leading pharma and biotech companies, powered by its unique NxWave™ GPCR structure-based drug discovery platform. Nxera Pharma operates at key locations in Tokyo and Osaka (Japan), London and Cambridge (UK), Basel (Switzerland) and Seoul (South Korea) and is listed on the Tokyo Stock Exchange (ticker: 4565).

For more information, please visit www.nxera.life
LinkedIn: @NxeraPharma | X: @NxeraPharma | YouTube: @NxeraPharma

Enquiries:

Nxera – Media and Investor Relations
Shinya Tsuzuki, VP, Head of Investor Relations
Maya Bennison, Communications Manager
+81 (0)3 5210 3399 | +44 (0)1223 949390 |IR@Nxera.life

MEDiSTRAVA (for International Media)
Mark Swallow, Frazer Hall, Erica Hollingsworth
+44 (0)203 928 6900 | Nxera@medistrava.com

Forward-looking statements
This press release contains forward-looking statements, including statements about the discovery, development, and commercialization of products. Various risks may cause Nxera Pharma Group’s actual results to differ materially from those expressed or implied by the forward looking statements, including: adverse results in clinical development programs; failure to obtain patent protection for inventions; commercial limitations imposed by patents owned or controlled by third parties; dependence upon strategic alliance partners to develop and commercialize products and services; difficulties or delays in obtaining regulatory approvals to market products and services resulting from development efforts; the requirement for substantial funding to conduct research and development and to expand commercialization activities; and product initiatives by competitors. As a result of these factors, prospective investors are cautioned not to rely on any forward-looking statements. We disclaim any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

SugarHarmony Consumer Concerns Under Investigation: Critiquing The Sugar Harmony Claims




SugarHarmony Consumer Concerns Under Investigation: Critiquing The Sugar Harmony Claims

An informational 2026 consumer evaluation examining common SugarHarmony search queries, ingredient transparency concerns, marketing claim context, refund and fulfillment policy requirements, and what verification steps consumers should complete before purchasing Sugar Harmony Drops

Tallmadge, OH, March 04, 2026 (GLOBE NEWSWIRE) — Where this report uses terms such as “critiquing” or “investigating,” it refers to a neutral review of publicly available marketing statements and policies as published by the company — not an opinion, endorsement, or performance judgment. All details should be verified on the official website.

This article contains affiliate links. If a purchase is made through these links, a commission may be earned at no additional cost to the buyer. This article is an informational overview and does not constitute medical, health, or dietary advice. All product details described below are stated as presented by the company and should be verified directly on the official website before any purchasing decision.

In this report, terms such as “results,” “support,” or “effectiveness” refer strictly to how Sugar Harmony Drops marketing materials describe potential outcomes. These terms do not indicate that Sugar Harmony Drops has been clinically proven effective as a finished proprietary formula.

Search activity around Sugar Harmony Drops has generated a pattern of consumer questions in early 2026 that go well beyond basic product information. Queries such as “is SugarHarmony legitimate,” “Sugar Harmony complaints,” “Sugar Harmony Drops side effects,” and similar intent terms reflect consumers trying to verify product information beyond promotional summaries. This report addresses those concern categories using only publicly available company documentation and ingredient-level research context.

This report evaluates what the company states, what its published policies require, and what ingredient-level research may suggest in general — without implying clinical proof for the finished product. It does not recommend for or against purchasing Sugar Harmony Drops.

Evidence standard used in this report: (1) company-published pages including the product page, refund policy, shipping policy, and terms of service; (2) ingredient-level peer-reviewed research where cited by the company; and (3) consumer verification steps that can be completed prior to purchase. Ingredient studies referenced below do not establish clinical proof of the finished Sugar Harmony Drops formula.

Current product details, pricing, and terms can be confirmed by viewing the current Sugar Harmony Drops offer (official Sugar Harmony Drops page).

Individual results vary. Dietary supplements are not substitutes for balanced nutrition, regular physical activity, or professional medical guidance. Consult a qualified healthcare provider before starting any new supplement regimen, particularly if you are currently managing an existing health condition or taking prescription medications.

What Consumer Concerns Around Sugar Harmony Drops Look Like in 2026

Consumer concern patterns in the supplement category tend to cluster around ingredient transparency, evidence type, refund requirements, fulfillment procedures, and brand accountability. Sugar Harmony Drops generates search queries across all five of those categories. Rather than addressing them with generic reassurances, this evaluation examines each concern against what the company’s own published materials actually state — and what they leave unaddressed.

Here is what consumers can verify independently versus what the company’s marketing materials state: the official website describes Sugar Harmony Drops as containing “all natural ingredients” and “maximum strength premium vitamins.” The company’s references section cites 32 published studies. What consumers can verify at this stage is whether the product publicly discloses specific per-ingredient amounts per serving — the official website materials reviewed for this report do not list per-ingredient milligram amounts — and whether any published study has tested the finished formula as sold. Publicly available sources reviewed for this report do not indicate one. That distinction shapes every concern addressed below.

Are the Sugar Harmony Drops Ingredients Backed by Research?

The official SugarHarmony website’s references section lists 32 scientific citations corresponding to ingredients associated with the formula. Referenced compounds include Gymnema Sylvestre, Chromium Picolinate, Bitter Melon, Cinnamon Extract, Green Tea Catechins, Astragalus Membranaceus, Grape Seed Extract, Forskolin, Korean Ginseng, Ashwagandha, Capsaicin, GABA, L-Carnitine, African Mango, and additional botanicals and amino acids.

Several of these ingredients have appeared in peer-reviewed research published in journals such as the Journal of Ethnopharmacology, Diabetes Care, American Journal of Clinical Nutrition, and Phytotherapy Research. Gymnema Sylvestre has been studied in relation to glucose metabolism markers in published nutrition research. Chromium Picolinate has been studied in relation to glucose metabolism parameters, though findings vary across study designs and dosages. Cinnamon and Bitter Melon each appear in metabolic health literature with varying degrees of evidence depending on study populations and dosing protocols.

The concern that matters most here isn’t whether these ingredients appear in published research — many of them do. The more relevant question is whether the specific dosages used in those published studies correspond to what Sugar Harmony Drops delivers per serving. The official product page and marketplace listings describe the formula using general terms but do not appear to disclose the specific milligram amount of each individual ingredient per serving.

The presence of scientific references can indicate ingredient-level research interest, but it does not confirm the dose, quality, or real-world outcomes of the finished Sugar Harmony Drops formula unless full per-ingredient amounts and product-level clinical data are publicly available. Without that per-ingredient dosage disclosure, consumers can’t independently map the cited research to the product’s actual per-serving composition.

Does Sugar Harmony Drops Have Clinical Trials as a Finished Product?

This is one of the most common points of confusion in supplement evaluation, and it applies broadly across the dietary supplement category — not just to this product.

A review of publicly available materials on the official website — including the product page, policies, and references — did not identify a published clinical trial evaluating Sugar Harmony Drops as a finished proprietary formula. The 32 scientific references on the product website correspond to studies on individual ingredients tested in isolation under specific research conditions. Those studies examined single compounds at known dosages — they didn’t evaluate the combined multi-ingredient liquid supplement as sold.

Under current federal regulations, dietary supplements are not required to undergo pre-market clinical testing or receive FDA approval before being sold. The FDA does not evaluate supplement efficacy claims prior to market entry. The company’s own website includes the standard regulatory disclaimer that statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent any disease.

Consumers researching terms such as “Sugar Harmony clinical study,” “SugarHarmony FDA approved,” “Sugar Harmony Drops proven,” or “does Sugar Harmony actually work” should understand that the distinction between ingredient-level research and product-level clinical validation is the key factor in interpreting the company’s scientific references. That’s standard across the supplement industry, but it’s especially important to understand when you’re making a health-related purchasing decision.

SugarHarmony Pricing Structure and the 6-Bottle Fulfillment Process

Publicly listed pricing on the official website includes multiple package formats — including multi-bottle options — with different total pricing and shipping terms. At the time this report was prepared, the site displayed pricing that varied by bottle quantity, with the 6-bottle option listed at $49 per bottle as an example. Other formats are also listed and may change. Because pricing and promotions can be updated at any time, consumers should confirm the current offer and checkout terms directly on the official product page before purchase.

Purchases are processed through ClickBank, which the company identifies as the retailer for this product. Pricing on the official website describes these as one-time purchases.

Consumers can confirm current pricing and availability by viewing the current Sugar Harmony Drops offer (official Sugar Harmony Drops page), as pricing may change at any time.

One area generating specific consumer questions involves the 6-bottle package fulfillment process. Per the company’s published Terms of Service, the 6-bottle offer includes a multi-step fulfillment procedure: only three bottles ship initially. The remaining three require the buyer to scan a QR code included with the shipment, navigate to a secure webpage, submit personal information including full name, email address, and order number, and complete this process within 60 days of the original purchase date.

The published terms state that missing the required request steps or deadline may result in not receiving the remaining bottles under that offer. Consumers considering the 6-bottle package should review the current fulfillment terms directly on the official website before selecting this option.

Sugar Harmony Drops Refund Policy: Requirements and Return Process

The company’s published refund policy describes a 60-day satisfaction guarantee from the date the order is shipped. If you’re unsatisfied within the guarantee period, the company states that you can request a full refund by contacting their support team.

The refund process includes specific requirements worth understanding before purchasing. All bottles must be returned — whether empty, full, or partially full — including any bonus or free bottles received as part of the order. Returns must be shipped to the fulfillment address at 285 Northeast Ave, Tallmadge, OH 44278 with a written note including the order ID, full name, address, email, and phone number.

The buyer is responsible for return shipping costs and must provide a tracking number. According to the published return policy, consumers should contact the support team and receive confirmation from an agent before initiating a return. Failing to do so could result in complications with locating the return and may delay the refund.

Refund processing timelines depend on the buyer’s financial institution. The company’s refund page states that processing may take several business days to appear on financial statements after the return has been received. Refund requests can also be initiated through ClickBank’s self-service billing portal.

Sugar Harmony Drops Marketing Language and Testimonial Context

Official marketing materials describe Sugar Harmony Drops as supporting an active lifestyle, containing maximum strength ingredients, promoting overall well-being, and being crafted with carefully selected natural ingredients. These are general wellness positioning statements consistent with how many dietary supplements are marketed.

Here is what the company states versus what consumers can verify regarding testimonials: the company’s disclaimer section states that testimonials, case studies, and examples are results forwarded by users and are not intended to represent or guarantee that anyone will achieve the same or similar results. The published terms also note that some names and personal identifying information may have been changed to protect privacy.

Testimonials describe individual experiences and do not establish typical outcomes. Consumers should interpret them alongside published disclaimers and the broader evidence limitations described in this report. When evaluating promotional content, look for specific outcome descriptions that include context about duration of use and accompanying lifestyle factors, and weigh those alongside the product’s regulatory context and the ingredient-versus-product research distinction outlined above.

Who Is Behind SugarHarmony?

Marketplace listings on Amazon associate the product with the brand name Syvor, while the official website operates under the name SugarHarmony Research. Payments are processed through ClickBank (Click Sales Inc.), and the fulfillment address is listed in Tallmadge, Ohio.

The official website does not prominently disclose specific details about the manufacturing facility, including GMP (Good Manufacturing Practices) certification status, the identity of the contract manufacturer, or third-party testing protocols. These are details that some consumers consider important when evaluating supplement quality and consistency.

Consumers who prioritize manufacturing transparency may want to contact the company directly at support@getsugarharmony.com to request additional information about production standards, ingredient sourcing, and quality assurance procedures before making a purchasing decision.

Verification Steps Consumers Often Use Before Purchasing

Confirm whether individual ingredient dosages are disclosed. Full-disclosure labeling allows you and your healthcare provider to compare per-serving amounts against published research. When specific amounts aren’t listed, consider contacting the manufacturer directly.

Understand the difference between ingredient research and finished-product research. Many supplements reference published studies on individual compounds. Fewer have been evaluated as finished multi-ingredient formulations. Knowing which type of evidence you’re looking at helps set realistic expectations.

Read the full terms of service before selecting a pricing package. Important details about fulfillment procedures, refund requirements, and purchase conditions are often found in the terms pages rather than on the main product page.

Verify that promotional content originates from official brand channels. Third-party advertising and intermediary pages may not reflect the company’s current terms, pricing, or product details. Confirm information directly on the official website.

Consult a qualified healthcare provider. This is especially important if you’re taking prescription medications or managing an existing health condition. A clinician familiar with your personal medical history is the most reliable resource for evaluating whether any supplement is appropriate for your situation.

Liquid Supplement Format Considerations in 2026

Marketed in a liquid drop format, this product represents one of several delivery methods used across the dietary supplement category. Liquid formulations are sometimes marketed with claims about absorption advantages compared to capsule or tablet formats. The bioavailability of any supplement depends on multiple factors, including the specific compounds involved, the formulation excipients, individual digestive health, and whether the product is taken with food.

Consumers evaluating liquid supplements should apply the same evidence standards they would apply to any other supplement format: look for per-ingredient dosage transparency, check for published research on the finished formulation where available, and consult a healthcare provider about whether the delivery format is relevant to their specific health considerations.

Who Might Consider Sugar Harmony Drops — and Who Might Not

Based on the product’s positioning and publicly available information, Sugar Harmony Drops may appeal to adults who prefer liquid supplement formats and who are exploring natural ingredient-based options as one component of a broader wellness approach that includes balanced nutrition, regular physical activity, and professional healthcare guidance.

It may be less suited for consumers who require transparent individual ingredient dosing to make clinical comparisons against published research, those who need medically validated interventions for a diagnosed condition, or anyone expecting significant changes from a single supplement without accompanying lifestyle modifications.

As with all dietary supplements, individual outcomes depend on personal health factors, and the FDA does not evaluate supplement efficacy claims before products reach the market.

Consumer Questions About Sugar Harmony Drops

Is SugarHarmony a legitimate product?

As a commercially available dietary supplement, it’s sold through the official website getsugarharmony.com and processed through ClickBank. The product is also listed on Amazon under the Syvor brand name. It references ingredients that appear in published peer-reviewed research at the ingredient level. The product has not been evaluated by the FDA, which is standard for dietary supplements under current federal regulations. Consumers should evaluate the product based on the information and considerations outlined in this report.

What are the most common concerns about Sugar Harmony Drops?

Consumer search patterns indicate questions about ingredient dosage transparency, the absence of finished-product clinical trials, the 6-bottle fulfillment process, refund timelines, and the distinction between ingredient-level research and product-level evidence. Each of these concerns is addressed in the sections above.

Does the product disclose individual ingredient amounts?

Publicly available product labeling and the official website describe the formula as containing all-natural ingredients and maximum strength premium vitamins. Specific milligram amounts per individual ingredient per serving do not appear to be publicly disclosed. Consumers may contact the manufacturer for additional details.

Is Sugar Harmony Drops FDA approved?

This product is a dietary supplement and does not require FDA approval under current federal regulations. The FDA does not evaluate supplement efficacy claims prior to market entry. The company’s website includes the standard FDA disclaimer.

How does the refund process work?

The company publishes a 60-day satisfaction guarantee from the shipping date. Refund requests require returning all bottles to the Tallmadge, Ohio fulfillment address with order details included. The buyer covers return shipping and must contact support before initiating the return. Processing timelines depend on the buyer’s financial institution. Requests may also be initiated through ClickBank’s billing portal.

What happens if I don’t complete the 6-bottle QR code process?

Per the company’s Terms of Service, missing the required steps or the 60-day deadline may result in not receiving the remaining three bottles under that offer. Consumers considering the 6-bottle package should review these terms carefully before purchasing.

Are testimonials on the website representative of typical results?

Published disclaimer language on the official website states that testimonials and case studies are results forwarded by users and are not intended to represent or guarantee similar outcomes. Some names and identifying information may have been changed. Consumers should evaluate testimonials alongside published disclaimers and the regulatory context described in this report.

Where is Sugar Harmony Drops manufactured?

The fulfillment address is in Tallmadge, Ohio. Marketplace listings associate the product with the Syvor brand. The official website does not prominently disclose specific manufacturing facility details or GMP certification status. Consumers may contact support for additional manufacturing information.

Can this product replace medical treatment for blood sugar management?

Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. This product should not be used as a replacement for professional medical treatment. Consumers managing blood sugar-related health conditions should consult their healthcare provider before starting any supplement and should continue any prescribed treatment regimen.

How does Sugar Harmony Drops compare to other supplements in this category?

This evaluation focuses specifically on Sugar Harmony Drops and does not provide comparative rankings. Consumers interested in comparative analysis should evaluate each product using the same verification framework: ingredient dosage transparency, published research type, manufacturing disclosure, and refund terms.

What’s the best way to verify claims independently?

Request per-ingredient dosage information from the manufacturer. Cross-reference disclosed amounts against dosages used in the cited published studies. Confirm current pricing, fulfillment terms, and refund policies on the official website. Consult a healthcare provider familiar with your medical history before purchasing any dietary supplement.

Additional Consumer Research

Independent research across multiple consumer publications, peer-reviewed sources, and regulatory guidance from the FDA may provide broader perspective on liquid dietary supplements, metabolic wellness ingredient research, and supplement evaluation frameworks. Evaluating multiple sources is recommended before making any purchasing decision.

Summary of Key Considerations

Consumer concerns around Sugar Harmony Drops center on ingredient dosage transparency, the distinction between ingredient-level and product-level research, the multi-step 6-bottle fulfillment process, and refund procedure requirements. The product references 32 published studies on individual ingredients, but publicly available sources do not indicate a clinical study evaluating the finished formula. Individual ingredient amounts per serving do not appear to be publicly disclosed. The company provides a 60-day refund guarantee processed through ClickBank, with specific return requirements outlined in their published policies.

Here is a final summary of what the company states versus what consumers can independently verify before purchasing: the company states the formula contains maximum strength natural ingredients backed by research. What consumers can verify is that the cited research pertains to individual ingredients studied in isolation, that per-ingredient dosages are not publicly disclosed for the finished product, and that the refund and fulfillment processes include specific procedural requirements detailed in the company’s published terms. Reviewing those terms directly is the most useful step any consumer can take before deciding.

Complete product details, current pricing, and published terms are available by viewing the current Sugar Harmony Drops offer (official Sugar Harmony Drops page).

Contact Information

Company: SugarHarmony Research

Return Address: 285 Northeast Ave, Tallmadge, OH 44278

Email: support@getsugarharmony.com

Support: (323) 388-4197

Website: getsugarharmony.com

Retailer (per website disclosure): Click Sales Inc., 1444 S. Entertainment Ave., Suite 410, Boise, ID 83709

Self-Service Billing Support: Available through ClickBank’s order support portal

ClickBank Order Support: https://www.clkbank.com/?

US: 1-800-390-6035

INT: 1-208-345-4245

Disclaimers

Content and Consumer Information Disclaimer: This article is an independent informational overview and does not constitute medical, health, dietary, financial, or legal advice. All product details, ingredient information, pricing, and policy terms described in this article are stated as presented by the company on its publicly available website and product labeling. This content has not been independently audited or verified unless specifically noted. Readers are encouraged to verify all claims directly with the manufacturer and to consult a qualified healthcare professional before beginning any dietary supplement.

Supplement and Health Notice: Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. The statements made by the manufacturer regarding this product have not been evaluated by the Food and Drug Administration. Individual results vary based on numerous factors including age, baseline health, dietary habits, activity level, and consistency of use. Health and wellness concerns should be discussed with a qualified healthcare provider who is familiar with the individual’s personal medical history.

Results, Pricing, and Product Variability: All pricing, bonus offers, shipping terms, and refund policies referenced in this article are based on information published on the official product website at the time of writing and may change without notice. Consumers should verify current terms on the official website and through ClickBank order support before completing any purchase.

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Purisaki Berberine Patches Claims Evaluated: 2026 Consumer Report on Transdermal Berberine Delivery, Patch Absorption Science, and What Buyers Should Verify




Purisaki Berberine Patches Claims Evaluated: 2026 Consumer Report on Transdermal Berberine Delivery, Patch Absorption Science, and What Buyers Should Verify

An informational 2026 consumer report examining Purisaki Berberine Patches’ transdermal delivery claims, ingredient research context, pricing structure, and what to confirm before purchasing

Wayne, NJ, March 04, 2026 (GLOBE NEWSWIRE) — This article contains affiliate links. If a purchase is made through these links, a commission may be earned at no additional cost to the buyer. This article is an independent informational report and does not provide medical advice or product recommendations. All product statements are presented as described by the company and should be verified on the official website. In this report, terms like “effective” or “works” refer only to marketing language and do not indicate clinical proof of the finished product.

Consumer search interest in berberine patches and transdermal supplement formats has continued to grow heading into 2026 — particularly among adults exploring non-pill alternatives to traditional capsules and those curious whether patch-based delivery changes how botanical compounds like berberine interact with the body.

Purisaki Berberine Patches have become one of the more visible products in this space. The company markets the patch as a plant-based transdermal wellness product, positioning it around the idea that berberine delivered through the skin may bypass the digestive limitations that have been well-documented in oral berberine research. That premise is central to the product’s marketing — but it also raises questions that deserve straightforward answers.

Is transdermal berberine delivery actually supported by published research? How do the weight management claims on the Purisaki product page hold up when you compare them to what the scientific literature says about berberine as a compound? And does a consumer adhesive patch deliver enough active ingredient to be meaningful?

This report walks through what the company states, what ingredient-level research supports under controlled conditions, and where the gaps sit between marketing language and product-level evidence. It doesn’t recommend for or against the product — it gives you the information you’d want before deciding for yourself.

Current product details, pricing, and terms can be confirmed by viewing the current Purisaki Berberine Patches offer (official Purisaki page).

Individual results vary. Dietary supplements are not substitutes for balanced nutrition, regular physical activity, or professional medical guidance. Consult a qualified healthcare provider before starting any new supplement regimen.

What Are Purisaki Berberine Patches

Purisaki Berberine Patches are transdermal supplement patches marketed as a plant-based formula for daily wellness and weight management support. The company describes them as an adhesive patch applied to the skin for an eight-hour wear period, positioned as a convenient alternative to traditional capsules and tablets.

The brand is operated by UAB BeWell EU, registered at Gynėjų St. 4-333, LT-01109 Vilnius, Lithuania (company registration number 305788600). Per the published Terms of Service, goods are manufactured and shipped from fulfillment centers that may be located outside the company’s office address, with the designated returns center at QuickBox Fulfillment, 415 Hamburg Turnpike, Building B, 07470 Wayne, NJ, United States.

Publicly available product information describes a multi-ingredient patch containing berberine extract, fucoxanthin extract, pomegranate oil (punicic acid extract), green tea extract, African mango extract, vitamins C, B1, and B3, plus additional natural ingredients. The delivery system is described as a multi-layer design featuring a breathable comfort layer, biodegradable protective outer layer, and a berberine release core layer for controlled delivery.

A 4.3-star average from over 8,658 reviews is displayed on the website. Individual ingredient concentrations per patch are not disclosed in publicly available materials. The standard FDA disclaimer on the site confirms that products and claims have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

Berberine Research Context: What Published Studies Examine vs. What Purisaki Claims

Berberine is a naturally occurring alkaloid found in plants including barberry, goldenseal, and Oregon grape. It’s one of the more thoroughly studied botanical compounds in the metabolic health space, and that research is worth understanding on its own terms before connecting it to any specific product.

A 2020 meta-analysis published in Clinical Nutrition ESPEN, covering 12 randomized controlled trials, found that oral berberine supplementation was associated with moderate but statistically significant reductions in body weight, BMI, waist circumference, and C-reactive protein in participants with metabolic disorders. A separate dose-response meta-analysis in Complementary Therapies in Clinical Practice reported significant influence on BMI and waist circumference across 10 studies. Review literature in Frontiers in Pharmacology concluded that berberine alone could reduce key metabolic markers including triglycerides, cholesterol, fasting glucose, and insulin resistance through AMPK pathway activation.

That’s real science on a real compound. But here’s where it gets important for anyone researching Purisaki specifically.

Every study referenced above examined oral berberine at disclosed dosages — typically 500 mg to 1,500 mg daily. Purisaki delivers berberine through a transdermal patch, which is a fundamentally different delivery mechanism. The published research on transdermal berberine in humans is substantially more limited. A 2018 pharmacokinetic study in PLOS ONE examined transdermal berberine formulations in animal models using pharmaceutical-grade cream bases. A 2024 study in Analytical and Bioanalytical Chemistry demonstrated that berberine loaded in chitosan microneedle arrays could permeate to both epidermis and dermis layers — but that examined microneedle technology, not a consumer adhesive patch.

Connecting the body of oral berberine research directly to a transdermal patch product would require published evidence showing comparable bioavailability through the skin. The stratum corneum — the skin’s outermost layer — acts as a selective barrier, and not all molecules pass through it with equal efficiency. That distinction matters when you’re comparing what’s been studied to what’s being marketed.

Marketing Claims: What’s Stated vs. What Can Be Verified

The official Purisaki product page includes marketing language such as “Lose 12+ lbs Per Month Easily” and “Feel The Change In 1 Week,” but independent clinical trials on the finished Purisaki patch product do not appear in the published literature. Consumers can confirm current claim language and terms on the official page.

For context, published meta-analyses on oral berberine — at known dosages, through oral delivery — found average weight reductions of approximately 2 kg (about 4.5 lbs) across study durations that varied from weeks to months. That’s substantially less than the 12-pound monthly figure in Purisaki’s marketing, and those studies examined oral supplementation rather than transdermal patch delivery.

The site’s own FAQ section separately states “consistent daily use for at least 90 days” is suggested for best results, which is more consistent with published berberine research timelines than the “1 week” marketing language on the main product page.

Additional claims describe berberine as helping “flip your metabolism from storage mode to burn mode” and reference “Scientifically Studied Plants” with “Ingredients proven to help control hunger and shrink waist size in days.” While individual ingredients have been studied in published research, the word “proven” in that context overstates the evidence: ingredient-level studies don’t validate a multi-ingredient patch formula, oral results don’t automatically apply to transdermal delivery, and “in days” doesn’t align with timelines in the published berberine literature.

This does not establish how the finished product performs. It clarifies what the published evidence does and does not confirm for this specific delivery format.

Transdermal Delivery: What’s Established and What’s Uncertain

Transdermal delivery is well-established in pharmaceutical applications. Nicotine patches, hormone replacement patches, and certain pain management patches all have extensive clinical validation. Those products are regulated and clinically tested in ways that differ from consumer botanical wellness patches, so their performance data cannot be used to infer outcomes for berberine patches. For botanical compounds like berberine, transdermal delivery through consumer adhesive patches represents a newer and less-studied application.

The practical question is whether berberine — a relatively large botanical molecule — can be absorbed through the skin at meaningful dosages via a standard adhesive patch. Published research exploring transdermal berberine has primarily used advanced delivery technologies like pharmaceutical-grade cream bases with penetration enhancers or microneedle arrays that create temporary micro-channels in the skin. Those are distinct from a consumer wellness patch.

Independent bioavailability data on the finished Purisaki patch product does not appear in the published literature. Without that data, there’s no way to independently confirm whether the patch delivers berberine at concentrations comparable to the oral dosages used in research studies. This is perhaps the most important gap for consumers to understand when assessing the product’s marketing claims.

What Consumers Are Searching — and What the Evidence Actually Addresses

People researching terms like “berberine patches,” “do berberine patches work,” “Purisaki berberine patch effectiveness,” “transdermal berberine delivery,” or “Purisaki weight loss results” are generally trying to answer the same core question: does this format deliver berberine in a way that produces the metabolic effects documented in published research?

The honest answer, based on currently available evidence, is that the published research primarily examines oral berberine at disclosed dosages between 500 mg and 1,500 mg daily. Transdermal berberine delivery through consumer adhesive patches has not been validated through independent clinical trials with published bioavailability data. That doesn’t rule out the possibility of benefit — it means the specific evidence gap between oral research and transdermal patch delivery hasn’t been closed by publicly available data.

Purisaki Berberine Patches Pricing

Pricing displayed on the official website at the time of writing ranged from approximately $35 to $70 depending on package selection, with shipping listed separately at $4.95. The site prominently displays discount language and states that special pricing may expire. A subscription option with recurring monthly billing is also available. Pricing, discounts, and package options can change and should be verified directly on the official site.

Consumers can confirm current pricing and availability by viewing the current Purisaki Berberine Patches offer (official Purisaki page), as pricing may change at any time.

Refund Policy and 60-Day Return Window

The published return policy provides a 60-day window from delivery. Returns within the first 14 days qualify for a full refund, while those initiated after 14 days but within the 60-day window may incur additional fees. A Return Merchandise Authorization (RMA) code from customer support is required before sending products back, and returns are accepted only at the designated fulfillment center address — not the company’s registered office.

Shipping costs are not refundable, and consumers cover return shipping. The company states refunds are processed within 14 days of receiving returned goods, issued to the original payment method. Actual appearance depends on the buyer’s financial institution. Complete return terms should be reviewed directly on the official website.

Testimonials: What’s Displayed and What Buyers Should Know

The website displays testimonials that describe outcomes including weight loss of 7, 15, and 16 pounds, reduced cravings, and improved energy, labeled “Verified Customer.” These outcomes have not been independently verified.

Section 11.2 of the published Terms of Service states that “all testimonials and/or comments displayed on the Website might have fictional names and associative pictures.” This means the names and images associated with testimonials may not represent actual customers. Section 11.4 separately notes the company reserves the right to moderate or decline to publish reviews not meeting content guidelines. The site’s FDA disclaimer also confirms that individual results may vary. Readers should factor all of these disclosures into how they interpret testimonial content.

Consumer Verification Checklist

Ask about per-patch ingredient dosages. Berberine amounts per patch are not publicly disclosed. If dosing matters to your decision-making — and it should, given that published research uses specific dosage ranges — contact the manufacturer directly.

Understand the oral-to-transdermal evidence gap. Published berberine studies examine oral supplementation. Transdermal delivery through consumer adhesive patches is a less-studied format with limited independent bioavailability data.

Check the Terms of Service for testimonial disclosures. Section 11.2 states names and images may be fictional. That’s worth reading before forming expectations based on testimonial content.

Confirm refund conditions before ordering. The 60-day window has different terms before and after the 14-day mark. An RMA code is required, and shipping costs are non-refundable.

Note the shipping origin and timeline. Per the Terms of Service, most goods ship from China. U.S. delivery estimates are 8-12 business days, and import duties may apply depending on local laws.

Consult a healthcare provider first. This applies especially for adults taking medications, managing chronic conditions, or with sensitive skin. The Terms of Service explicitly state goods “are not for sensitive skin” and recommend a 24-hour patch test before first use.

Who Might Be Researching This Product in 2026

Based on the published positioning, Purisaki Berberine Patches appear to target adults who prefer non-pill supplement formats and are interested in berberine as one component of a broader wellness approach that includes balanced nutrition and physical activity.

Consumers who require transparent per-ingredient dosing for clinical comparison, those seeking a format backed by established bioavailability data, or individuals expecting significant weight loss from a single product without lifestyle changes may find the current evidence base insufficient for their decision-making.

As stated in the standard FDA disclaimer displayed on the company’s website, the product’s statements have not been evaluated by the FDA and the product is not intended to diagnose, treat, cure, or prevent any disease.

Consumer Questions About Purisaki Berberine Patches

How do berberine patches differ from capsules?

Patches are designed to deliver berberine through the skin, bypassing digestive metabolism. The theoretical advantage is avoiding the well-documented bioavailability challenges of oral berberine. However, clinical evidence specifically validating consumer adhesive patches for berberine delivery is more limited than the oral research base, and the two formats haven’t been directly compared in published studies.

Does the FDA regulate Purisaki Berberine Patches?

Dietary supplements do not require FDA approval before being sold under current federal regulations. The FDA disclaimer on the Purisaki website confirms this directly.

How much berberine does each patch contain?

Specific amounts per patch are not disclosed in publicly available product materials. Published oral berberine studies showing metabolic effects typically use 500 mg to 1,500 mg daily — a useful reference point when comparing any berberine product to published research.

Can the weight loss claims be independently verified?

The marketing language states consumers can “Lose 12+ lbs Per Month Easily.” Published meta-analyses on oral berberine found average reductions of approximately 2 kg across study durations at known oral dosages. Independent clinical testing of the finished Purisaki patch product does not appear in the published literature.

Are the website testimonials independently verified?

The Terms of Service (Section 11.2) disclose that testimonial names and images may be fictional. The testimonial outcomes described on the site have not been independently verified.

What is the refund process?

A 60-day return window applies from delivery. Full refunds apply to returns within 14 days; later returns may incur fees. An RMA code is required from customer support, shipping costs are non-refundable, and processing takes up to 14 days after goods are received.

Where is the product manufactured and shipped from?

Per the Terms of Service, most goods are manufactured and delivered from China. The brand’s operating company is registered in Vilnius, Lithuania, with returns processed through a fulfillment center in Wayne, New Jersey.

Is this product safe for sensitive skin?

The Terms of Service explicitly state that goods “are not for sensitive skin” and recommend a 24-hour test before first use. Anyone with a skin condition should consult a healthcare provider before using transdermal patch products.

How long does the company recommend using the patches?

The FAQ section states that consistent daily use for at least 90 days is suggested for best results. Published oral berberine research examines intervention periods ranging from several weeks to several months, generally consistent with that timeline.

Is there a subscription, and can I cancel?

Yes, a subscription option exists with recurring monthly billing. Cancellation is available anytime through customer support. Whether the current or next month’s shipment is affected depends on whether the order has already been dispatched.

Additional Consumer Research

Independent research across multiple peer-reviewed sources and healthcare provider resources may provide broader perspective on berberine supplementation, transdermal delivery science, and weight management products. Consulting multiple sources is recommended before making any purchasing decision.

Summary of Key Considerations

As a transdermal supplement product, Purisaki Berberine Patches position themselves around berberine’s published metabolic research while using a patch delivery format that is less studied than oral supplementation. The product contains berberine and additional botanical ingredients, though individual amounts per patch are not publicly disclosed.

Published berberine research — primarily examining oral supplementation at known dosages — has found moderate effects on metabolic markers including body weight, BMI, and waist circumference. Independent clinical testing of the finished Purisaki patch product does not appear in the published literature, and the gap between oral berberine research and transdermal patch delivery remains an important consideration for consumers doing their own research.

The marketing claim of “Lose 12+ lbs Per Month” significantly exceeds the weight loss figures reported in published oral berberine meta-analyses. Testimonials on the website are accompanied by a Terms of Service disclosure stating names and images may be fictional, and outcomes described have not been independently verified.

Complete product details, current pricing, and published terms are available by viewing the current Purisaki Berberine Patches offer (official Purisaki page).

Contact Information

Brand: Purisaki Berberine Patches

Operating Company: UAB BeWell EU

Registered Address: Gynėjų St. 4-333, LT-01109 Vilnius, Lithuania

Company Registration No.: 305788600

Returns Address: Returns – QuickBox Fulfillment, 415 Hamburg Turnpike, Building B, 07470 Wayne, NJ, United States

Email: support@purisaki.com

Phone (US): +1 (850) 389-0125

Phone (UK): +442080891401

Phone (DE): +498004009820

Website: https://trypurisaki.com/

Disclaimers

Content and Consumer Information Disclaimer: This article is an independent informational overview and does not constitute medical, health, dietary, financial, or legal advice. All product details, ingredient information, pricing, and policy terms described in this article are stated as presented by the company on its publicly available website and product labeling. This content has not been independently audited or verified unless specifically noted. Readers are encouraged to verify all claims directly with the manufacturer and to consult a qualified healthcare professional before beginning any dietary supplement.

Supplement and Health Notice: Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. The statements made by the manufacturer regarding this product have not been evaluated by the Food and Drug Administration. Individual results vary based on numerous factors including age, baseline health, dietary habits, activity level, and consistency of use. Weight management concerns should be discussed with a qualified healthcare provider familiar with the individual’s personal medical history.

Results, Pricing, and Product Variability: All pricing, shipping terms, and refund policies referenced in this article are based on information published on the official product website at the time of writing and may change without notice. Consumers should verify current terms through the official website before completing any purchase.

FTC Affiliate Disclosure and Publisher Responsibility: This article contains affiliate links. If a product is purchased through these links, a commission may be earned at no additional cost to the buyer. The publisher of this article is not responsible for typographical errors, manufacturer changes to the product after publication, or individual consumer outcomes.

CONTACT: Email: support@purisaki.com
Phone (US): +1 (850) 389-0125
Phone (UK): +442080891401
Phone (DE): +498004009820