Premier Health Reports 2026 First Quarter Results

Premier Health Reports 2026 First Quarter Results




Premier Health Reports 2026 First Quarter Results

MONTRÉAL, Feb. 25, 2026 (GLOBE NEWSWIRE) — Premier Health of America Inc. (TSX-V: PHA) (the “Company”), a leading Canadian Healthtech company, announces it has filed its unaudited Quarterly Consolidated Financial Statements and MD&A for its first quarter ended December 31, 2025.

Highlights
(in thousands of Canadian dollars)   Dec. 31, 2025
(3 months)
Dec. 31, 2024
(3 months)
Revenues   17,835   32,132  
Gross margin(1)   2,726   5,137  
Gross margin as a % of revenues   15.28 % 16.0 %
Adjusted EBITDA(1)   5   705  
Net Loss   (2,549 ) (2,261 )


(1) 
See the Company’s MD&A for details on these non-GAAP measures.

Summary

  • Adjusted EBITDA for the quarter was $5K ($0.7M for the same period last year), mainly driven by a decline in the British Columbia market.
  • Net Loss for the quarter was $2.5M (loss of $2.3M for the same period last year).

The travel nurse and northern communities services are generally performing well, except in British Columbia, where the Company experienced a reduction in volume. This decline is attributable to a service acquisition centralization initiative undertaken by the health authorities, which is expected to ultimately favour the most competitive service providers such as SSI. During the quarter, the Company formally discontinued its Per Diem and Transportation operations, as these lines of business were no longer profitable, and has since focused its resources on its Travel Nurse operations across Canada.

“Our cost reduction plan is still progressing, and additional efforts were deployed in the current quarter. The Per Diem and transportation operations were abandoned this quarter, and our focus has fully shifted to Travel Nurses. In the short term, we remain committed to cost reduction, debt management, operational efficiency, and pursuing organic growth opportunities,” said Guy D’Aoust, Interim CEO of Premier Health.

More information can be found in the Company’s Quarterly Consolidated Financial Statements and MD&A as available on SEDAR+ at sedarplus.ca.

About Premier Health

Premier Health is a leading Canadian Healthtech company that provides a comprehensive range of outsourced services solutions for healthcare needs to governments, companies, and individuals. Premier Health uses its proprietary LiPHe® platform to lead the digital transformation of the healthcare services sector, providing patients with faster, more affordable, and more accessible care.

Non-GAAP Measures

Earnings before interest, taxes, depreciation, and amortization (“EBITDA”), is calculated as the net profit (loss), before non-recurring items excluding acquisition and transaction costs, non-cash expenses (including loss from disposal of assets, impairments, amortization, and depreciation), change in fair values, interest expense, and income tax expense (recovery). Adjusted EBITDA excludes Share-based compensation and unusual items, as determined from time to time. Gross margin is either used as a number or a percentage. As a number, it means Revenues minus Direct Costs. When used as a percentage, it means the ratio of Revenues minus Direct Costs to Revenues. More detail can be found in PHA’s Management Discussion and Analysis.

For Further Information Please Contact:

Mr. Guy D’Aoust

Interim Chief Executive Officer

Premier Health of America Inc.

gdaoust@premierhealth.ca / 1 800 231 9916

Mr. Frédéric St-Cyr

Interim Chief Financial Officer

Premier Health of America Inc.

fstcyr@premierhealth.ca / 1 800 231 9916


Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION:

This press release contains forward-looking information within the meaning of applicable securities legislation which reflects the current plans and expectations of the Company with respect to future events and financial performance. All statements other than statements of historical or current facts may be forward-looking information. Forward-looking information includes statements that are predictive in nature, depend upon or refer to future events or conditions, or include words such as ‘believes’, ‘continues’, ‘expects’, ‘projects’, ‘anticipates’, ‘plans’, ‘estimates’, ‘seeks’, ‘intends’, ‘targets’, ‘forecasts’, or negative or grammatical versions thereof and other similar expressions, or future or conditional verbs such as ‘may’, ‘will’, ‘should’, ‘would’ and ‘could’. Forward-looking information in this press release includes, but is not limited to, statements with respect to the execution of the Company’s growth strategy. Forward-looking information is based on management’s plans, estimates, projections, beliefs and opinions as at the date of this release, and the assumptions related to those plans, estimates, projections, beliefs and opinions may change; therefore, they are presented for the purpose of assisting the Company’s security holders in understanding management’s views at such time regarding those future outcomes and may not be appropriate for other purposes. Although the forward-looking information contained in this release is based on assumptions which the Company believes are reasonable, there can be no assurance that actual results will be consistent with such forward-looking information. The forward-looking information in this release relate only to events or information as of the date on which the statements are made and, except as specifically required by applicable securities laws, the Company undertakes no obligation to update or revise publicly any forward-looking information, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. There can be no assurance that the forward-looking information will prove to be accurate. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance, or achievements to be materially different from those implied by such statements. The Company assumes no responsibility to update or revise forward-looking information to reflect new events or circumstances unless required by law. These factors and others are more fully discussed in the filings of the Company with Canadian securities regulatory authorities available on SEDAR+ at www.sedarplus.ca

LENSAR® Provides Update on Pending Acquisition by Alcon

LENSAR® Provides Update on Pending Acquisition by Alcon




LENSAR® Provides Update on Pending Acquisition by Alcon

ORLANDO, Fla., Feb. 25, 2026 (GLOBE NEWSWIRE) — LENSAR, Inc. (Nasdaq: LNSR) (“LENSAR” or the “Company”), a global medical technology company focused on advanced robotic laser solutions for the treatment of cataracts, today provided an update on the status of its pending acquisition by Alcon Research, LLC (“Alcon”).

The Company and Alcon continue to cooperate with the U.S. Federal Trade Commission (the “FTC”) staff in connection with its Request for Additional Information and Documentary Material (the “Second Request”) and related review of the proposed acquisition of the Company by Alcon (the “Alcon Transaction”). In light of this continued review process, the Company currently expects to close the transaction in the first half of 2026, subject to satisfaction of the applicable closing conditions, including receipt of regulatory approval from the FTC.

About LENSAR

LENSAR is a commercial-stage medical device company focused on designing, developing, and marketing advanced systems for the treatment of cataracts and the management of astigmatism as an integral aspect of the procedure. LENSAR has developed its ALLY Robotic Cataract Laser System™ as a compact, highly ergonomic system utilizing an extremely fast dual-modality laser and integrating AI into proprietary imaging and software. ALLY is designed to transform premium cataract surgery by utilizing LENSAR’s advanced robotic technologies with the ability to perform the entire procedure in a sterile operating room or in-office surgical suite, delivering operational efficiencies and reduced overhead. ALLY includes LENSAR’s proprietary Streamline® software technology, designed to guide surgeons to achieve better outcomes.

Forward-looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including, without limitation, statements regarding the Alcon Transaction, regulatory review of the Alcon Transaction and the expected timing of the closing of the Alcon Transaction. In some cases, you can identify forward-looking statements by terms such as “aim,” “anticipate,” “approach,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “goal,” “intend,” “look,” “may,” “mission,” “plan,” “possible,” “potential,” “predict,” “project,” “pursue,” “should,” “target,” “will,” “would,” or the negative thereof and similar words and expressions.

Forward-looking statements are based on management’s current expectations, beliefs and assumptions and on information currently available to us. Such statements are subject to a number of known and unknown risks, uncertainties and assumptions, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various important factors, including, but not limited to: (i) the Alcon Transaction may not be completed in a timely manner or at all, including the risk that any required regulatory approvals are not obtained, are delayed or are subject to unanticipated conditions that could adversely affect the Company; (ii) the possibility that any or all of the various conditions to the consummation of the Alcon Transaction may not be satisfied or waived; (iii) the occurrence of any event, change or other circumstance that could give rise to the termination of the merger agreement related to the Alcon Transaction, including in circumstances which would require the Company to pay a termination fee or other expenses; (iv) the effect of the announcement or pendency of the merger on the Company’s ability to retain and hire key personnel, (v) the incurrence of transaction costs or adverse effects on its operating results and business generally; (vi) adverse consequences of legal proceedings instituted against the Company following the announcement of the Alcon Transaction; and (vii) the Company’s stock price may decline significantly if the Alcon Transaction is not consummated. In addition, a number of other important factors could cause the Company’s actual future results and other future circumstances to differ materially from those expressed in any forward-looking statements, including but not limited to the other important factors that are disclosed under the heading “Risk Factors” contained in the Company’s Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2025 filed with the Securities and Exchange Commission (“SEC”), as such factors may be updated from time to time in its other filings with the SEC, including the Company’s Annual Report on Form 10-K for the year ended December 31, 2025, to be filed with the SEC, each accessible on the SEC’s website at www.sec.gov and the Investor Relations section of the Company’s website at https://ir.lensar.com.

All forward-looking statements are expressly qualified in their entirety by such factors. Except as required by law, the Company undertakes no obligation to publicly update or review any forward-looking statement, whether because of new information, future developments or otherwise. These forward-looking statements should not be relied upon as representing the Company’s views as of any date subsequent to the date of this press release.

Contacts:   Lee Roth
Thomas R. Staab, II, CFO   Burns McClellan for LENSAR
ir.contact@lensar.com   lroth@burnsmc.com

Revolution Medicines Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress

Revolution Medicines Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress




Revolution Medicines Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress

  • On track for readout of RASolute 302, a Phase 3 trial of daraxonrasib in second line metastatic PDAC, in first half of 2026
  • Continues to advance broad late-stage pipeline, with five ongoing Phase 3 trials and three additional Phase 3 trials planned to initiate in 2026
  • Expects to substantially complete enrollment in RASolve 301, a Phase 3 trial of daraxonrasib in previously treated NSCLC, this year
  • Initiated RASolute 305, the first Phase 3 trial for zoldonrasib, in first line metastatic PDAC harboring a RAS G12D mutation
  • Revolution Medicines to hold webcast today at 4:30 p.m. Eastern Time

REDWOOD CITY, Calif., Feb. 25, 2026 (GLOBE NEWSWIRE) — Revolution Medicines, Inc. (Nasdaq: RVMD), a late-stage clinical oncology company developing targeted therapies for patients with RAS-addicted cancers, today announced its financial results for the quarter and full year ended December 31, 2025, and provided an update on corporate progress.

“We made substantial clinical progress over the past year continuing to advance our broad portfolio of RAS(ON) inhibitors across multiple tumor types and disease settings,” said Mark A. Goldsmith, M.D., Ph.D., chief executive officer and chairman of Revolution Medicines. “Our focus remains on executing high-quality clinical programs and leveraging our innovation platform to discover and develop potentially groundbreaking approaches aimed at improving outcomes for patients with RAS-addicted cancers. We expect a pivotal readout from RASolute 302 in the first half of 2026, which represents an important milestone for daraxonrasib, for patients with pancreatic cancer, and for our RAS(ON)-targeting strategy overall.”

Recent Clinical Highlights

Pancreatic Ductal Adenocarcinoma (PDAC)

Daraxonrasib in PDAC

Daraxonrasib, a pioneering RAS(ON) multi-selective inhibitor, has shown an unprecedented clinical profile as monotherapy and in various combinations, including a RAS(ON) inhibitor doublet. The company is currently evaluating daraxonrasib in three randomized Phase 3 studies in PDAC:

  • RASolute 302: Global enrollment is complete in the randomized registrational trial evaluating daraxonrasib monotherapy in patients with second line (2L) metastatic disease. A readout is expected in the first half of 2026.
  • RASolute 303: Initiation is underway for the registrational trial evaluating daraxonrasib both as monotherapy and in combination with chemotherapy in patients with first line (1L) metastatic disease.
  • RASolute 304: Enrollment is ongoing in the registrational trial evaluating daraxonrasib monotherapy in the adjuvant setting in patients with resectable disease following surgery and conventional perioperative chemotherapy.

Zoldonrasib in PDAC

Zoldonrasib, an innovative RAS(ON) G12D-selective covalent inhibitor, has shown a highly differentiated safety and tolerability profile as monotherapy and is also being evaluated in a range of combinations.

In January, the company disclosed encouraging initial data from the combination of zoldonrasib plus FOLFIRINOX in patients with 1L metastatic PDAC. Nineteen patients were available for evaluation as of the December 1 data cutoff date. The initial safety and tolerability profile of the combination was largely consistent with the well-known profile of modified FOLFIRINOX alone, with high zoldonrasib dose intensity maintained. With a median follow-up of 3.9 months (2.7 – 8.0 months), 63% of patients achieved a partial response, either confirmed or pending confirmation. The disease control rate was 95% and most patients remained on treatment as of the data cutoff date. The company plans to share initial clinical data evaluating the combinations of zoldonrasib plus gemcitabine nab-paclitaxel and the RAS(ON) inhibitor doublet of zoldonrasib plus daraxonrasib at one or more medical meetings this year.

The company is advancing two 1L Phase 3 combination studies incorporating zoldonrasib this year:

  • RASolute 305: The randomized, double-blind, placebo-controlled registrational trial, evaluating zoldonrasib in combination with investigator’s choice of either gemcitabine nab-paclitaxel or modified FOLFIRINOX compared to investigator’s choice of the chemotherapies with placebo, has been initiated.
  • RASolute 309: The company plans to initiate, in the second half of 2026, a registrational trial evaluating the RAS(ON) inhibitor doublet combination of zoldonrasib plus daraxonrasib.

Non-Small Cell Lung Cancer (NSCLC)

Daraxonrasib in NSCLC

RASolve 301, a global, randomized Phase 3 trial evaluating daraxonrasib monotherapy in patients with previously treated NSCLC, continues enrolling patients in the U.S. and globally; the company anticipates substantially completing enrollment this year.

The company also expects to disclose its plans for advancing daraxonrasib combination therapy in 1L NSCLC this year.

Zoldonrasib in NSCLC

The company has reported highly encouraging safety/tolerability and antitumor activity with zoldonrasib in patients with previously treated NSCLC harboring a RAS G12D mutation. A zoldonrasib monotherapy expansion cohort of 2L and beyond patients has fully enrolled, and earlier this year zoldonrasib was awarded FDA Breakthrough Therapy designation in this setting, making it the company’s third RAS(ON) inhibitor to have received this distinction.

The company is preparing to initiate, in the first half of 2026, RASolve 308, a randomized, placebo-controlled Phase 3 trial of zoldonrasib in combination with standard of care as a 1L treatment for patients with metastatic RAS G12D NSCLC.

Elironrasib in NSCLC

For elironrasib, the company has reported a differentiated clinical profile in both RAS G12C inhibitor-naïve and G12C inhibitor-experienced NSCLC patients. Elironrasib has demonstrated encouraging results as monotherapy and in combination with either pembrolizumab or as part of a RAS(ON) inhibitor doublet with daraxonrasib.

The company plans to share an update on its registrational vision for elironrasib in 2026.

Colorectal Cancer (CRC)

Given the genetically complex and heterogeneous nature of colorectal cancer, the company believes combinatorial approaches are key to maximizing clinical impact. The company has a range of combination trials underway, including evaluating RAS(ON) inhibitor doublets and combinations with current standards of care and other novel investigational approaches.

The company plans to share updated combination data in CRC this year as it looks toward potential pivotal trial opportunities.

Clinical Collaborations

The company’s development efforts include several clinical collaborations studying its RAS(ON) inhibitors with other targeted therapies:

  • Under a collaboration with Summit Therapeutics, Inc., the APEX-103 trial is evaluating Revolution Medicines’ RAS(ON) inhibitors with ivonescimab, Summit’s PD-1/VEGF bispecific antibody, across multiple solid tumor settings. The first patient was recently dosed in this clinical trial.
  • A collaborative trial with Tango Therapeutics, Inc. is evaluating Revolution Medicines’ RAS(ON) inhibitors in combination with vopimetostat, Tango’s MTA-cooperative PRMT5 inhibitor, in patients with tumors carrying both a RAS mutation and MTAP deletion.
  • The company also recently entered into a clinical collaboration with Bristol Myers Squibb to evaluate daraxonrasib in combination with navlimetostat, Bristol Myers Squibb’s MTA-cooperative PRMT5 inhibitor, in patients with pancreatic cancer whose tumors carry both a RAS mutation and MTAP deletion. This collaboration extends Revolution Medicines’ commitment to evaluating novel targeted agents, such as PRMT5 inhibitors, that may be appropriate to combine with RAS(ON) inhibitors in some settings.

Early-Stage Programs

RMC-5127

The company recently advanced its fourth RAS(ON) inhibitor, the RAS(ON) G12V-selective inhibitor RMC-5127, into the clinic and announced that the first patient was dosed in a first-in-human trial.

The company expects to identify a recommended monotherapy Phase 2 dose for this compound in the second half of 2026.

Innovative New Class of RAS(ON) Inhibitors

The company continues to discover novel approaches that have the potential to further transform treatment paradigms for patients living with RAS-addicted cancers.

In January, the company introduced an innovative new class of RAS(ON) inhibitors designed to overcome RAS-driven acquired drug resistance and extend the clinical benefit of its RAS(ON) portfolio. A compound from this class of RAS(ON) inhibitors, RM-055, was shown to drive deep and durable tumor regressions in preclinical PDAC and NSCLC models that had developed resistance to a RAS multi-selective inhibitor.

The company plans to share more information about this new class of compounds at an upcoming scientific meeting, and plans to initiate a Phase 1 trial with the first compound from this class of RAS(ON) inhibitors in the fourth quarter of this year.

Financial Highlights

Fourth Quarter Results

Cash Position: Cash, cash equivalents and marketable securities were $2.0 billion as of December 31, 2025. This balance includes the receipt of the first royalty monetization tranche of $250 million in June 2025 from the company’s partnership with Royalty Pharma, and there remains an additional $1.75 billion in future committed capital under this arrangement.

R&D Expenses: Research and development expenses were $294.9 million for the quarter ended December 31, 2025, compared to $188.1 million for the quarter ended December 31, 2024. The increase was primarily due to an increase in clinical trial and manufacturing expenses for daraxonrasib, zoldonrasib, and elironrasib, and an increase in personnel-related expenses and stock-based compensation expense related to additional headcount.

G&A Expenses: General and administrative expenses were $66.7 million for the quarter ended December 31, 2025, compared to $28.2 million for the quarter ended December 31, 2024. The increase in G&A expenses was primarily due to increases in commercial preparation activities, and personnel-related expenses and stock-based compensation related to additional headcount.

Net Loss: Net loss was $364.9 million for the quarter ended December 31, 2025, compared to net loss of $194.6 million for the quarter ended December 31, 2024.

Full Year 2025 Financial Highlights

R&D Expenses: Research and development expenses were $987.3 million for the year ended December 31, 2025, compared to $592.2 million for the year ended December 31, 2024. The increase was primarily due to an increase in clinical trial and manufacturing expenses for daraxonrasib, zoldonrasib, and elironrasib, and an increase in personnel-related expenses and stock-based compensation related to additional headcount.

G&A Expenses: General and administrative expenses were $195.0 million for the year ended December 31, 2025 compared to $97.3 million for the year ended December 31, 2024. The increase in G&A expenses was primarily due to increases in commercial preparation activities, and personnel-related expenses and stock-based compensation related to additional headcount.

Net Loss: Net loss was $1.1 billion for the year ended December 31, 2025, compared to net loss of $600.1 million for the year ended December 31, 2024.

2026 Financial Guidance

Revolution Medicines expects full year 2026 GAAP operating expenses to be between $1.6 and $1.7 billion, which includes estimated non-cash stock-based compensation expense of between $180 and $200 million.

Webcast
Revolution Medicines will host a webcast this afternoon, February 25, 2026, at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time). To listen to the live webcast, or access the archived webcast, please visit: https://ir.revmed.com/events-and-presentations. Following the live webcast, a replay will be available on the company’s website for at least 14 days.

About Revolution Medicines, Inc.
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Additional development opportunities in the company’s pipeline focus on RAS(ON) mutant-selective inhibitors, including RMC-0708 (Q61H) and RMC-8839 (G13C). For more information, please visit www.revmed.com and follow us on LinkedIn.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this press release that are not historical facts may be considered “forward-looking statements,” including without limitation statements regarding the company’s financial projections and guidance; the company’s development opportunities, plans and timelines and its ability to build or advance its portfolio and R&D pipeline; progression of clinical studies and findings from these studies, including the tolerability, safety, and potential efficacy of the company’s candidates being studied; the company’s expectations regarding timing of clinical trial strategies, initiation, enrollment and data readouts or disclosures and clinical trial designs; the company’s ability discover and develop approaches that improve outcomes for patients with RAS-addicted cancers; collaborations, including the aims and expected benefits of the company’s collaborations with Summit, Tango, and Bristol Myers Squibb; plans for developing any of the company’s product candidates as part of a combination treatment; sources of capital, including the availability of capital under the Royalty Pharma arrangement and whether the company achieves the milestones associated with certain payments thereunder.

Forward-looking statements are typically, but not always, identified by the use of words such as “aims,” “anticipate,” “believe,” “estimate,” “expect,” “plan,” “potential,” “project,” “up to,” “will” and other similar terminology indicating future results. Such forward-looking statements are subject to substantial risks and uncertainties that could cause the company’s development programs, future results, performance, or achievements to differ materially from those anticipated in the forward-looking statements. Such risks and uncertainties include without limitation risks and uncertainties inherent in the drug development process, including the company’s programs’ development stages, the process of designing and conducting preclinical and clinical trials, the regulatory approval processes, the timing of regulatory filings, the challenges associated with manufacturing drug products, the company’s ability to successfully establish, protect and defend its intellectual property, other matters that could affect the sufficiency of the company’s capital resources to fund operations, reliance on third parties for manufacturing and development efforts, changes in the competitive landscape, and the effects on the company’s business of the global events, such as international conflicts or global pandemics. For a further description of the risks and uncertainties that could cause actual results to differ from those anticipated in these forward-looking statements, as well as risks relating to the business of Revolution Medicines in general, see Revolution Medicines’ Annual Report on Form 10-K filed with the Securities and Exchange Commission (the “SEC”) on February 25, 2026, and its future periodic reports to be filed with the SEC. Except as required by law, Revolution Medicines undertakes no obligation to update any forward-looking statements to reflect new information, events, or circumstances, or to reflect the occurrence of unanticipated events.

Revolution Medicines Media & Investor Contact:
media@revmed.com
investors@revmed.com

REVOLUTION MEDICINES, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(in thousands, except share and per share data)
 
  Three Months Ended
December 31,
 
Year Ended December 31,
  2025   2024   2025   2024
Operating Expenses:                    
Research and development $ 294,943     $ 188,096     $ 987,332     $ 592,225  
General and administrative 66,683     28,214     195,037     97,299  
Total operating expenses 361,626     216, 310     1,182,369     689,524  
Loss from operations (361,626 )   (216,310 )   (1,182,369 )   (689,524 )
Non-operating income (expense), net:                    
Interest income 21,292     21,225     90,694     86,883  
Interest expense (11,936 )   —     (24,231 )   —  
Change in fair value of warrant liability and contingent earn-out shares (12,627 )   (17 )   (15,358 )   4,323  
Other income (expense), net 5     (220 )   (37 )   (2,528 )
Total non-operating income (loss), net (3,266 )   20,988     51,068     88, 678  
Loss before income taxes (364,892 )   (195,322 )   (1,131,301 )   (600,846 )
Benefit (loss) from income taxes —     753     —     753  
Net loss $ (364,892 )   $ (194,569 )   $ (1,131,301 )   $ (600,093 )
Net loss per share attributable to common stockholders – basic and diluted $ (1.86 )   $ (1.12 )   (5.95 )   $ (3.58 )
Weighted-average common shares used to compute net loss per share, basic and diluted 196,669,886     173,758,250     190,129,154     167,737,672  


 

REVOLUTION MEDICINES, INC.
SELECTED CONDENSED CONSOLIDATED BALANCE SHEETS
(in thousands, unaudited)
 
    December 31,
2025
    December 31,
2024
       
                 
Cash, cash equivalents and marketable securities   $ 2,025,679     $ 2,289,299  
Working capital (1)     1,784,613       2,163,718  
Total assets     2,354,508       2,558,301  
Total liabilities     723,211       293,097  
Total stockholders’ equity     1,631,297       2,265,204  

(1) Working capital is defined as current assets less current liabilities.

Revolution Medicines Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress

Revolution Medicines Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress




Revolution Medicines Reports Fourth Quarter and Full Year 2025 Financial Results and Update on Corporate Progress

  • On track for readout of RASolute 302, a Phase 3 trial of daraxonrasib in second line metastatic PDAC, in first half of 2026
  • Continues to advance broad late-stage pipeline, with five ongoing Phase 3 trials and three additional Phase 3 trials planned to initiate in 2026
  • Expects to substantially complete enrollment in RASolve 301, a Phase 3 trial of daraxonrasib in previously treated NSCLC, this year
  • Initiated RASolute 305, the first Phase 3 trial for zoldonrasib, in first line metastatic PDAC harboring a RAS G12D mutation
  • Revolution Medicines to hold webcast today at 4:30 p.m. Eastern Time

REDWOOD CITY, Calif., Feb. 25, 2026 (GLOBE NEWSWIRE) — Revolution Medicines, Inc. (Nasdaq: RVMD), a late-stage clinical oncology company developing targeted therapies for patients with RAS-addicted cancers, today announced its financial results for the quarter and full year ended December 31, 2025, and provided an update on corporate progress.

“We made substantial clinical progress over the past year continuing to advance our broad portfolio of RAS(ON) inhibitors across multiple tumor types and disease settings,” said Mark A. Goldsmith, M.D., Ph.D., chief executive officer and chairman of Revolution Medicines. “Our focus remains on executing high-quality clinical programs and leveraging our innovation platform to discover and develop potentially groundbreaking approaches aimed at improving outcomes for patients with RAS-addicted cancers. We expect a pivotal readout from RASolute 302 in the first half of 2026, which represents an important milestone for daraxonrasib, for patients with pancreatic cancer, and for our RAS(ON)-targeting strategy overall.”

Recent Clinical Highlights

Pancreatic Ductal Adenocarcinoma (PDAC)

Daraxonrasib in PDAC

Daraxonrasib, a pioneering RAS(ON) multi-selective inhibitor, has shown an unprecedented clinical profile as monotherapy and in various combinations, including a RAS(ON) inhibitor doublet. The company is currently evaluating daraxonrasib in three randomized Phase 3 studies in PDAC:

  • RASolute 302: Global enrollment is complete in the randomized registrational trial evaluating daraxonrasib monotherapy in patients with second line (2L) metastatic disease. A readout is expected in the first half of 2026.
  • RASolute 303: Initiation is underway for the registrational trial evaluating daraxonrasib both as monotherapy and in combination with chemotherapy in patients with first line (1L) metastatic disease.
  • RASolute 304: Enrollment is ongoing in the registrational trial evaluating daraxonrasib monotherapy in the adjuvant setting in patients with resectable disease following surgery and conventional perioperative chemotherapy.

Zoldonrasib in PDAC

Zoldonrasib, an innovative RAS(ON) G12D-selective covalent inhibitor, has shown a highly differentiated safety and tolerability profile as monotherapy and is also being evaluated in a range of combinations.

In January, the company disclosed encouraging initial data from the combination of zoldonrasib plus FOLFIRINOX in patients with 1L metastatic PDAC. Nineteen patients were available for evaluation as of the December 1 data cutoff date. The initial safety and tolerability profile of the combination was largely consistent with the well-known profile of modified FOLFIRINOX alone, with high zoldonrasib dose intensity maintained. With a median follow-up of 3.9 months (2.7 – 8.0 months), 63% of patients achieved a partial response, either confirmed or pending confirmation. The disease control rate was 95% and most patients remained on treatment as of the data cutoff date. The company plans to share initial clinical data evaluating the combinations of zoldonrasib plus gemcitabine nab-paclitaxel and the RAS(ON) inhibitor doublet of zoldonrasib plus daraxonrasib at one or more medical meetings this year.

The company is advancing two 1L Phase 3 combination studies incorporating zoldonrasib this year:

  • RASolute 305: The randomized, double-blind, placebo-controlled registrational trial, evaluating zoldonrasib in combination with investigator’s choice of either gemcitabine nab-paclitaxel or modified FOLFIRINOX compared to investigator’s choice of the chemotherapies with placebo, has been initiated.
  • RASolute 309: The company plans to initiate, in the second half of 2026, a registrational trial evaluating the RAS(ON) inhibitor doublet combination of zoldonrasib plus daraxonrasib.

Non-Small Cell Lung Cancer (NSCLC)

Daraxonrasib in NSCLC

RASolve 301, a global, randomized Phase 3 trial evaluating daraxonrasib monotherapy in patients with previously treated NSCLC, continues enrolling patients in the U.S. and globally; the company anticipates substantially completing enrollment this year.

The company also expects to disclose its plans for advancing daraxonrasib combination therapy in 1L NSCLC this year.

Zoldonrasib in NSCLC

The company has reported highly encouraging safety/tolerability and antitumor activity with zoldonrasib in patients with previously treated NSCLC harboring a RAS G12D mutation. A zoldonrasib monotherapy expansion cohort of 2L and beyond patients has fully enrolled, and earlier this year zoldonrasib was awarded FDA Breakthrough Therapy designation in this setting, making it the company’s third RAS(ON) inhibitor to have received this distinction.

The company is preparing to initiate, in the first half of 2026, RASolve 308, a randomized, placebo-controlled Phase 3 trial of zoldonrasib in combination with standard of care as a 1L treatment for patients with metastatic RAS G12D NSCLC.

Elironrasib in NSCLC

For elironrasib, the company has reported a differentiated clinical profile in both RAS G12C inhibitor-naïve and G12C inhibitor-experienced NSCLC patients. Elironrasib has demonstrated encouraging results as monotherapy and in combination with either pembrolizumab or as part of a RAS(ON) inhibitor doublet with daraxonrasib.

The company plans to share an update on its registrational vision for elironrasib in 2026.

Colorectal Cancer (CRC)

Given the genetically complex and heterogeneous nature of colorectal cancer, the company believes combinatorial approaches are key to maximizing clinical impact. The company has a range of combination trials underway, including evaluating RAS(ON) inhibitor doublets and combinations with current standards of care and other novel investigational approaches.

The company plans to share updated combination data in CRC this year as it looks toward potential pivotal trial opportunities.

Clinical Collaborations

The company’s development efforts include several clinical collaborations studying its RAS(ON) inhibitors with other targeted therapies:

  • Under a collaboration with Summit Therapeutics, Inc., the APEX-103 trial is evaluating Revolution Medicines’ RAS(ON) inhibitors with ivonescimab, Summit’s PD-1/VEGF bispecific antibody, across multiple solid tumor settings. The first patient was recently dosed in this clinical trial.
  • A collaborative trial with Tango Therapeutics, Inc. is evaluating Revolution Medicines’ RAS(ON) inhibitors in combination with vopimetostat, Tango’s MTA-cooperative PRMT5 inhibitor, in patients with tumors carrying both a RAS mutation and MTAP deletion.
  • The company also recently entered into a clinical collaboration with Bristol Myers Squibb to evaluate daraxonrasib in combination with navlimetostat, Bristol Myers Squibb’s MTA-cooperative PRMT5 inhibitor, in patients with pancreatic cancer whose tumors carry both a RAS mutation and MTAP deletion. This collaboration extends Revolution Medicines’ commitment to evaluating novel targeted agents, such as PRMT5 inhibitors, that may be appropriate to combine with RAS(ON) inhibitors in some settings.

Early-Stage Programs

RMC-5127

The company recently advanced its fourth RAS(ON) inhibitor, the RAS(ON) G12V-selective inhibitor RMC-5127, into the clinic and announced that the first patient was dosed in a first-in-human trial.

The company expects to identify a recommended monotherapy Phase 2 dose for this compound in the second half of 2026.

Innovative New Class of RAS(ON) Inhibitors

The company continues to discover novel approaches that have the potential to further transform treatment paradigms for patients living with RAS-addicted cancers.

In January, the company introduced an innovative new class of RAS(ON) inhibitors designed to overcome RAS-driven acquired drug resistance and extend the clinical benefit of its RAS(ON) portfolio. A compound from this class of RAS(ON) inhibitors, RM-055, was shown to drive deep and durable tumor regressions in preclinical PDAC and NSCLC models that had developed resistance to a RAS multi-selective inhibitor.

The company plans to share more information about this new class of compounds at an upcoming scientific meeting, and plans to initiate a Phase 1 trial with the first compound from this class of RAS(ON) inhibitors in the fourth quarter of this year.

Financial Highlights

Fourth Quarter Results

Cash Position: Cash, cash equivalents and marketable securities were $2.0 billion as of December 31, 2025. This balance includes the receipt of the first royalty monetization tranche of $250 million in June 2025 from the company’s partnership with Royalty Pharma, and there remains an additional $1.75 billion in future committed capital under this arrangement.

R&D Expenses: Research and development expenses were $294.9 million for the quarter ended December 31, 2025, compared to $188.1 million for the quarter ended December 31, 2024. The increase was primarily due to an increase in clinical trial and manufacturing expenses for daraxonrasib, zoldonrasib, and elironrasib, and an increase in personnel-related expenses and stock-based compensation expense related to additional headcount.

G&A Expenses: General and administrative expenses were $66.7 million for the quarter ended December 31, 2025, compared to $28.2 million for the quarter ended December 31, 2024. The increase in G&A expenses was primarily due to increases in commercial preparation activities, and personnel-related expenses and stock-based compensation related to additional headcount.

Net Loss: Net loss was $364.9 million for the quarter ended December 31, 2025, compared to net loss of $194.6 million for the quarter ended December 31, 2024.

Full Year 2025 Financial Highlights

R&D Expenses: Research and development expenses were $987.3 million for the year ended December 31, 2025, compared to $592.2 million for the year ended December 31, 2024. The increase was primarily due to an increase in clinical trial and manufacturing expenses for daraxonrasib, zoldonrasib, and elironrasib, and an increase in personnel-related expenses and stock-based compensation related to additional headcount.

G&A Expenses: General and administrative expenses were $195.0 million for the year ended December 31, 2025 compared to $97.3 million for the year ended December 31, 2024. The increase in G&A expenses was primarily due to increases in commercial preparation activities, and personnel-related expenses and stock-based compensation related to additional headcount.

Net Loss: Net loss was $1.1 billion for the year ended December 31, 2025, compared to net loss of $600.1 million for the year ended December 31, 2024.

2026 Financial Guidance

Revolution Medicines expects full year 2026 GAAP operating expenses to be between $1.6 and $1.7 billion, which includes estimated non-cash stock-based compensation expense of between $180 and $200 million.

Webcast
Revolution Medicines will host a webcast this afternoon, February 25, 2026, at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time). To listen to the live webcast, or access the archived webcast, please visit: https://ir.revmed.com/events-and-presentations. Following the live webcast, a replay will be available on the company’s website for at least 14 days.

About Revolution Medicines, Inc.
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Additional development opportunities in the company’s pipeline focus on RAS(ON) mutant-selective inhibitors, including RMC-0708 (Q61H) and RMC-8839 (G13C). For more information, please visit www.revmed.com and follow us on LinkedIn.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this press release that are not historical facts may be considered “forward-looking statements,” including without limitation statements regarding the company’s financial projections and guidance; the company’s development opportunities, plans and timelines and its ability to build or advance its portfolio and R&D pipeline; progression of clinical studies and findings from these studies, including the tolerability, safety, and potential efficacy of the company’s candidates being studied; the company’s expectations regarding timing of clinical trial strategies, initiation, enrollment and data readouts or disclosures and clinical trial designs; the company’s ability discover and develop approaches that improve outcomes for patients with RAS-addicted cancers; collaborations, including the aims and expected benefits of the company’s collaborations with Summit, Tango, and Bristol Myers Squibb; plans for developing any of the company’s product candidates as part of a combination treatment; sources of capital, including the availability of capital under the Royalty Pharma arrangement and whether the company achieves the milestones associated with certain payments thereunder.

Forward-looking statements are typically, but not always, identified by the use of words such as “aims,” “anticipate,” “believe,” “estimate,” “expect,” “plan,” “potential,” “project,” “up to,” “will” and other similar terminology indicating future results. Such forward-looking statements are subject to substantial risks and uncertainties that could cause the company’s development programs, future results, performance, or achievements to differ materially from those anticipated in the forward-looking statements. Such risks and uncertainties include without limitation risks and uncertainties inherent in the drug development process, including the company’s programs’ development stages, the process of designing and conducting preclinical and clinical trials, the regulatory approval processes, the timing of regulatory filings, the challenges associated with manufacturing drug products, the company’s ability to successfully establish, protect and defend its intellectual property, other matters that could affect the sufficiency of the company’s capital resources to fund operations, reliance on third parties for manufacturing and development efforts, changes in the competitive landscape, and the effects on the company’s business of the global events, such as international conflicts or global pandemics. For a further description of the risks and uncertainties that could cause actual results to differ from those anticipated in these forward-looking statements, as well as risks relating to the business of Revolution Medicines in general, see Revolution Medicines’ Annual Report on Form 10-K filed with the Securities and Exchange Commission (the “SEC”) on February 25, 2026, and its future periodic reports to be filed with the SEC. Except as required by law, Revolution Medicines undertakes no obligation to update any forward-looking statements to reflect new information, events, or circumstances, or to reflect the occurrence of unanticipated events.

Revolution Medicines Media & Investor Contact:
media@revmed.com
investors@revmed.com

REVOLUTION MEDICINES, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(in thousands, except share and per share data)
 
  Three Months Ended
December 31,
 
Year Ended December 31,
  2025   2024   2025   2024
Operating Expenses:                    
Research and development $ 294,943     $ 188,096     $ 987,332     $ 592,225  
General and administrative 66,683     28,214     195,037     97,299  
Total operating expenses 361,626     216, 310     1,182,369     689,524  
Loss from operations (361,626 )   (216,310 )   (1,182,369 )   (689,524 )
Non-operating income (expense), net:                    
Interest income 21,292     21,225     90,694     86,883  
Interest expense (11,936 )   —     (24,231 )   —  
Change in fair value of warrant liability and contingent earn-out shares (12,627 )   (17 )   (15,358 )   4,323  
Other income (expense), net 5     (220 )   (37 )   (2,528 )
Total non-operating income (loss), net (3,266 )   20,988     51,068     88, 678  
Loss before income taxes (364,892 )   (195,322 )   (1,131,301 )   (600,846 )
Benefit (loss) from income taxes —     753     —     753  
Net loss $ (364,892 )   $ (194,569 )   $ (1,131,301 )   $ (600,093 )
Net loss per share attributable to common stockholders – basic and diluted $ (1.86 )   $ (1.12 )   (5.95 )   $ (3.58 )
Weighted-average common shares used to compute net loss per share, basic and diluted 196,669,886     173,758,250     190,129,154     167,737,672  


 

REVOLUTION MEDICINES, INC.
SELECTED CONDENSED CONSOLIDATED BALANCE SHEETS
(in thousands, unaudited)
 
    December 31,
2025
    December 31,
2024
       
                 
Cash, cash equivalents and marketable securities   $ 2,025,679     $ 2,289,299  
Working capital (1)     1,784,613       2,163,718  
Total assets     2,354,508       2,558,301  
Total liabilities     723,211       293,097  
Total stockholders’ equity     1,631,297       2,265,204  

(1) Working capital is defined as current assets less current liabilities.

PROCEPT BioRobotics Reports Fourth Quarter 2025 Financial Results and Updates 2026 Revenue Guidance

PROCEPT BioRobotics Reports Fourth Quarter 2025 Financial Results and Updates 2026 Revenue Guidance




PROCEPT BioRobotics Reports Fourth Quarter 2025 Financial Results and Updates 2026 Revenue Guidance

SAN JOSE, Calif., Feb. 25, 2026 (GLOBE NEWSWIRE) — PROCEPT BioRobotics® Corporation (Nasdaq: PRCT) (the “Company”), a surgical robotics company focused on advancing patient care by developing transformative solutions in urology, today reported unaudited financial results for the quarter ended December 31, 2025.

“In the fourth quarter, we delivered our highest procedure volume to date—approximately 12,200—and sold 65 new systems, marking our strongest capital quarter,” said Larry Wood, Chief Executive Officer. “At the same time, we took meaningful steps to position the Company for its next phase of growth. To sharpen our focus on delivering durable procedure growth, we realigned our commercial organization, established a dedicated launch team to reduce activation variability, and implemented a more disciplined handpiece pricing strategy. Furthermore, we successfully reduced field inventory levels and eliminated end-of-quarter purchasing incentives, which led to a fourth quarter revenue shortfall but improved handpiece average selling price by approximately 5%.”

Fourth Quarter 2025 Financial Results

  • Total revenue of $76.4 million for the fourth quarter of 2025, an increase of 12% compared to the prior year period in 2024
  • U.S. procedures of approximately 12,200 for the fourth quarter of 2025, an increase of approximately 69% compared to the prior year period
  • U.S. handpieces sold of approximately 9,400 for the fourth quarter of 2025, an increase of approximately 7% compared to the prior year period
  • Fourth quarter of 2025 handpiece average selling price increased 5% sequentially to $3,340
  • 2025 ending U.S. install base of 718 systems, representing a 42% increase compared to the prior year period
  • International revenue of $9.8 million for the fourth quarter of 2025, an increase of 25% compared to the prior year period in 2024

Total revenue for the fourth quarter of 2025 was $76.4 million, an increase of 12% compared to the prior year period. U.S. revenue was $66.6 million, representing growth of 10% compared to the prior year period. The increase was primarily driven by increased handpiece revenue. U.S. handpiece and consumable revenue for the fourth quarter of 2025 was $34.0 million, an increase of 16% compared to the prior year period. U.S. system revenue for the fourth quarter of 2025 was $27.6 million, which was flat compared to the prior year period. As of December 31, 2025, the install base of robotic systems in the U.S. was 718 systems, an increase of 42% compared to the prior year period. International revenue was $9.8 million for the quarter, an increase of 25% compared to the prior year period.

Gross margin for the fourth quarter 2025 was 61% compared to 64% in the prior year period. Gross margin decline in the fourth quarter was primarily driven by lower-than-expected U.S. consumable revenue, as well as a one-time cost associated with a voluntary field action.

Operating expenses in the fourth quarter of 2025 were $77.4 million, compared with $63.4 million in the prior year period. The increase in operating expenses reflects continued investment to support commercial expansion, innovation across our BPH platform technology and increased funding for our Water IV Prostate Cancer trial.

Net loss was $29.8 million for the fourth quarter of 2025, compared to a loss of $18.9 million in the prior year period. Adjusted EBITDA* was a loss of $19.0 million for the fourth quarter of 2025, compared to a loss of $10.3 million in the prior year period.

Cash, cash equivalents and restricted cash balances as of December 31, 2025, totaled $289.5 million.

Full Year 2025 Financial Results
Revenue for the full year 2025 was $308.1 million, an increase of 37% compared to the prior year period. The growth was primarily driven by increases in U.S. revenue attributable to system placements and increased handpieces sold.

Gross margin for full year 2025 was 64%, compared to 61% for the full year 2024. Gross margin improvement was primarily due to improved overhead absorption and favorable revenue mix of U.S. handpieces sold.

Operating expenses were $300.1 million for the full year 2025, compared to $233.7 million for the full year 2024, an increase of 28%. The increase was driven by increased sales and marketing expenses primarily to expand the commercial organization, and increased research and development and general and administrative expenses.

Net loss was $95.6 million for the full year 2025, compared to $91.4 million for the full year 2024. Adjusted EBITDA was a loss of $50.2 million for full year 2024, compared to a loss of $61.1 million for the full year 2024.

Full Year 2026 Financial Guidance
“Historically, handpiece unit sales exceeded procedure volumes by approximately 8% to 16%. Going forward, we expect handpiece unit sales and procedure volumes to be closely aligned,” said Larry Wood. “While annual U.S. procedure growth will be in the range of 39% to 48%, our decision to forecast procedure and handpiece volumes in close alignment has reduced our projected 2026 handpiece revenue guidance; however, this impact is meaningfully offset by higher handpiece prices of $3,500 per unit. Considering these factors, together with the short-term disruption associated with the sales force realignment, we are resetting our 2026 guidance to $390 to $410 million, representing annual growth of 27% to 33%. We believe these actions are essential to our long-term goals of sustained high growth and establishing a favorable financial profile.”

  • The Company expects revenue for the full year 2026 to be in the range of $390 million to $410 million, which represents growth of 27% to 33% compared to the prior year period
  • The Company expects full year 2026 U.S. procedure growth to be in the range of 39% to 48% compared to the prior year period
  • The Company expects full year 2026 gross margin to be approximately 65%
  • The Company expects full year 2026 operating expenses to be approximately $350 million
  • The Company expects full year 2026 adjusted EBITDA* loss to be in the range of $30 million to $17 million

First Quarter 2026 Financial Guidance

  • The Company expects total procedures for the first quarter of 2026 to be in the range of 12,000 to 12,800, which represents growth of 31% to 36% compared to the prior year period.
  • Total revenue for the first quarter of 2026 is expected to be in the range of $79 million to $82 million dollars, which represents growth of 14% to 19% to the prior year period.

*Adjusted EBITDA is a financial measure that is not prepared in accordance with generally accepted accounting principles in the United States (GAAP). For more information about the Company’s use of non-GAAP financial measures, please see the section below titled “Use of Non-GAAP Financial Measures (Unaudited).

Webcast and Conference Call Information
PROCEPT BioRobotics will host a conference call to discuss the fourth quarter 2025 financial results on Wednesday, February 25, 2026, at 4:30 p.m. Eastern Time.

Investors interested in listening to the conference call may do so by following one of the links below:

Investor Day in New York and Webcast
The Company will also host an in-person investor day event on Thursday, February 26, 2026, at the NASDAQ Headquarters in New York City beginning at 8:00am Eastern Time. A live, as well as an archived recording, will be available on the “Investors” section of the Company’s website at https://ir.procept-biorobotics.com.

About PROCEPT BioRobotics Corporation
PROCEPT BioRobotics’ mission is to revolutionize BPH treatment globally in partnership with urologists by delivering best-in-class robotic solutions that positively impact patients and drive value. PROCEPT BioRobotics manufactures the AQUABEAM® and HYDROS® Robotic Systems. The HYDROS Robotic System is the only AI-Powered, robotic technology that delivers Aquablation® therapy. PROCEPT BioRobotics designed Aquablation therapy to deliver effective, safe, and durable outcomes for males suffering from lower urinary tract symptoms or LUTS, due to BPH that are independent of prostate size and shape or surgeon experience. BPH is the most common prostate disease and impacts approximately 40 million men in the United States. The Company has developed a significant and growing body of clinical evidence with over 150 peer-reviewed publications, supporting the benefits and clinical advantages of Aquablation therapy.

Use of Non-GAAP Financial Measures (Unaudited)
This press release references Adjusted EBITDA, a financial measure that is not prepared in accordance with generally accepted accounting principles in the United States (GAAP). The Company defines Adjusted EBITDA as earnings before interest expense, taxes, depreciation and amortization and stock-based compensation. Non-GAAP financial measures are not a substitute for or superior to measures of financial performance prepared in accordance with GAAP and should not be considered as an alternative to any other performance measures derived in accordance with GAAP.

The Company believes that presenting Adjusted EBITDA provides useful supplemental information to investors about the Company in understanding and evaluating its operating results, enhancing the overall understanding of its past performance and future prospects, and allowing for greater transparency with respect to key financial metrics used by its management in financial and operational decision making. However, there are a number of limitations related to the use of non-GAAP measures and their nearest GAAP equivalents. For example, other companies may calculate non-GAAP measures differently, or may use other measures to calculate their financial performance, and therefore any non-GAAP measures the Company uses may not be directly comparable to similarly titled measures of other companies.

Forward Looking Statements
This release contains forward‐looking statements within the meaning of federal securities laws, including with respect to the Company’s projected financial performance for full year 2026, statements regarding the potential utilities, values, benefits and advantages of Aquablation therapy performed using PROCEPT BioRobotics’ products, including AquaBeam or Hydros Robotic Systems, which involve risks and uncertainties that could cause the actual results to differ materially from the anticipated results and expectations expressed in these forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements. Forward-looking statements are only predictions based on the Company’s current expectations, estimates, and assumptions, valid only as of the date they are made, and subject to risks and uncertainties, some of which the Company is not currently aware.   Forward-looking statements may include statements regarding financial guidance, market opportunity and penetration, procedure growth, the Company’s possible or assumed future results of operations, including descriptions of the Company’s revenues, gross margins, profitability, operating expenses, installed base growth, commercial momentum and overall business strategy. Forward‐looking statements should not be read as a guarantee of future performance or results and may not necessarily be accurate indications of the times at, or by, which such performance or results will be achieved. These forward‐looking statements are based on the Company’s current expectations and inherently involve significant risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in such forward‐looking statements as a result of these risks and uncertainties. These risks and uncertainties are described more fully in the section titled “Risk Factors” in the Company’s filings with the Securities and Exchange Commission (the “SEC”), including the Company’s annual report on Form 10-K filed with the SEC on February 27, 2025, and amended on April 11, 2025, and subsequent quarterly reports on Form 10-Q. PROCEPT BioRobotics does not undertake any obligation to update forward‐looking statements and expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward‐looking statements contained herein. These forward-looking statements should not be relied upon as representing PROCEPT BioRobotics’ views as of any date subsequent to the date of this press release.

Important Safety Information
All surgical treatments have inherent and associated side effects. For a list of potential side effects visit https://aquablation.com/safety-information/

Investor Contact:
Matt Bacso
VP, Investor Relations and Business Operations
m.bacso@procept-biorobotics.com

 
PROCEPT BioRobotics Corporation
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited, in thousands, except per share data)
 
    Three Months Ended
December 31,
  Twelve Months Ended
December 31,
      2025       2024       2025       2024  
Revenue   $ 76,383     $ 68,236     $ 308,054     $ 224,498  
Cost of sales     30,070       24,564       111,828       87,399  
Gross profit     46,313       43,672       196,226       137,099  
Operating expenses:                
Research and development     19,056       15,066       71,277       62,298  
Selling, general and administrative     58,298       48,316       228,808       171,415  
Total operating expenses     77,354       63,382       300,085       233,713  
Loss from operations     (31,041 )     (19,710 )     (103,859 )     (96,614 )
Interest expense     (894 )     (969 )     (3,586 )     (4,184 )
Interest and other income, net     2,280       2,191       12,063       9,753  
Loss before income taxes     (29,655 )     (18,488 )     (95,382 )     (91,045 )
Provision for income taxes     190       368       190       368  
Net loss   $ (29,845 )   $ (18,856 )   $ (95,572 )   $ (91,413 )
Net loss per share, basic and diluted   $ (0.53 )   $ (0.35 )   $ (1.72 )   $ (1.75 )
Weighted-average common shares used to                
Compute net loss per share attributable to                
Common shareholders, basic and diluted     56,071       55,838       55,544       52,125  

 
PROCEPT BioRobotics Corporation
RECONCILIATION OF GAAP NET LOSS TO ADJUSTED EBITDA
(Unaudited, in thousands)
 
    Three Months Ended
December 31,
  Twelve Months Ended
December 31,
      2025       2024       2025       2024  
Net loss   $ (29,845 )   $ (18,856 )   $ (95,572 )   $ (91,413 )
Depreciation and amortization expense     1,709       1,453       6,390       5,234  
Stock-based compensation expense     10,842       9,085       47,603       31,840  
Interest (income) and interest expense, net     (1,719 )     (2,017 )     (8,632 )     (6,711 )
Adjusted EBITDA   $ (19,013 )   $ (10,335 )   $ (50,211 )   $ (61,050 )

 
PROCEPT BioRobotics Corporation
RECONCILIATION OF GAAP NET LOSS TO ADJUSTED 2026 EBITDA Guidance
(Unaudited, in thousands)
 
    For the Year Ending
December 31, 2026
    LOW   HIGH
Net loss   $ (91,500 )   $ (78,500 )
Depreciation and amortization expense     7,500       7,500  
Stock-based compensation expense     59,000       59,000  
Interest (income) and interest expense, net     (5,000 )     (5,000 )
Adjusted EBITDA   $ (30,000 )   $ (17,000 )

 
PROCEPT BioRobotics Corporation
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited, in thousands)
 
    December 31, 2025   December 31, 2024
Assets        
Current assets:        
Cash and cash equivalents   $ 286,503     $ 333,725  
Accounts receivable, net     83,533       83,496  
Inventory     70,694       56,168  
Prepaid expenses and other current assets     9,648       8,453  
Total current assets     450,378       481,842  
Restricted cash, non-current     3,038       3,038  
Property and equipment, net     30,399       26,709  
Operating lease right-of-use assets, net     17,538       18,941  
Intangible assets, net     709       932  
Other assets     6,019       2,555  
Total assets   $ 508,081     $ 534,017  
         
Liabilities and Stockholders’ Equity        
Current liabilities:        
Accounts payable   $ 17,285     $ 10,032  
Accrued compensation     23,175       21,537  
Deferred revenue     13,048       9,565  
Operating leases, current     2,214       1,910  
Loan facility liability     —       2,000  
Other current liabilities     10,073       8,089  
Total current liabilities     65,795       53,133  
Long-term debt     51,615       51,472  
Operating leases, non-current     24,654       26,868  
Other liabilities     147       324  
Total liabilities     142,211       131,797  
         
Stockholders’ equity:        
Additional paid-in capital     1,007,390       948,091  
Accumulated other comprehensive gain     37       114  
Accumulated deficit     (641,557 )     (545,985 )
Total stockholders’ equity     365,870       402,220  
Total liabilities and stockholders’ equity   $ 508,081     $ 534,017  

                                 
PROCEPT BioRobotics Corporation
REVENUE BY TYPE AND GEOGRAPHY
(Unaudited, in thousands)

                                 
    Three Months Ended
December 31,
  Twelve Months Ended
December 31,
      2025       2024       2025       2024  
U.S.                        
System sales and rentals   $ 27,600     $ 27,636     $ 93,000     $ 78,614  
Handpieces and other consumables     34,001       29,325       159,669       110,542  
Service     4,986       3,428       17,709       11,316  
Total U.S. revenue     66,587       60,389       270,378       200,472  
Outside of U.S.                        
System sales and rentals     2,953       3,711       13,132       11,685  
Handpieces and other consumables     5,977       3,684       21,777       10,914  
Service     866       452       2,767       1,427  
Total outside of U.S. revenue     9,796       7,847       37,676       24,026  
Total revenue   $ 76,383     $ 68,236     $ 308,054     $ 224,498  
                         

 
PROCEPT BioRobotics Corporation
QUARTERLY U.S. INSTALL BASE AND PROCEDURES
(Unaudited, in thousands)
 
  Q1’23   Q2’23   Q3’23   Q4’23   Q1’24   Q2’24   Q3’24   Q4’24   Q1’25   Q2’25   Q3’25   Q4’25   FY 23   FY 24   FY 25
U.S. Install Base                                                          
Beginning install base 167   192   233   271   315   354   400   445   505   547   595   653   167   315   505
Systems placed 25   41   38   44   39   46   45   60   42   48   58   65   148   190   213
Ending install base 192   233   271   315   354   400   445   505   547   595   653   718   315   505   718
                                                           
U.S Procedures (000) 3.0   3.6   4.3   5.6   6.1   7.0   7.4   7.2   9.3   10.8   11.0   12.2   16.5   27.7   43.3

PROCEPT BioRobotics Reports Fourth Quarter 2025 Financial Results and Updates 2026 Revenue Guidance

PROCEPT BioRobotics Reports Fourth Quarter 2025 Financial Results and Updates 2026 Revenue Guidance




PROCEPT BioRobotics Reports Fourth Quarter 2025 Financial Results and Updates 2026 Revenue Guidance

SAN JOSE, Calif., Feb. 25, 2026 (GLOBE NEWSWIRE) — PROCEPT BioRobotics® Corporation (Nasdaq: PRCT) (the “Company”), a surgical robotics company focused on advancing patient care by developing transformative solutions in urology, today reported unaudited financial results for the quarter ended December 31, 2025.

“In the fourth quarter, we delivered our highest procedure volume to date—approximately 12,200—and sold 65 new systems, marking our strongest capital quarter,” said Larry Wood, Chief Executive Officer. “At the same time, we took meaningful steps to position the Company for its next phase of growth. To sharpen our focus on delivering durable procedure growth, we realigned our commercial organization, established a dedicated launch team to reduce activation variability, and implemented a more disciplined handpiece pricing strategy. Furthermore, we successfully reduced field inventory levels and eliminated end-of-quarter purchasing incentives, which led to a fourth quarter revenue shortfall but improved handpiece average selling price by approximately 5%.”

Fourth Quarter 2025 Financial Results

  • Total revenue of $76.4 million for the fourth quarter of 2025, an increase of 12% compared to the prior year period in 2024
  • U.S. procedures of approximately 12,200 for the fourth quarter of 2025, an increase of approximately 69% compared to the prior year period
  • U.S. handpieces sold of approximately 9,400 for the fourth quarter of 2025, an increase of approximately 7% compared to the prior year period
  • Fourth quarter of 2025 handpiece average selling price increased 5% sequentially to $3,340
  • 2025 ending U.S. install base of 718 systems, representing a 42% increase compared to the prior year period
  • International revenue of $9.8 million for the fourth quarter of 2025, an increase of 25% compared to the prior year period in 2024

Total revenue for the fourth quarter of 2025 was $76.4 million, an increase of 12% compared to the prior year period. U.S. revenue was $66.6 million, representing growth of 10% compared to the prior year period. The increase was primarily driven by increased handpiece revenue. U.S. handpiece and consumable revenue for the fourth quarter of 2025 was $34.0 million, an increase of 16% compared to the prior year period. U.S. system revenue for the fourth quarter of 2025 was $27.6 million, which was flat compared to the prior year period. As of December 31, 2025, the install base of robotic systems in the U.S. was 718 systems, an increase of 42% compared to the prior year period. International revenue was $9.8 million for the quarter, an increase of 25% compared to the prior year period.

Gross margin for the fourth quarter 2025 was 61% compared to 64% in the prior year period. Gross margin decline in the fourth quarter was primarily driven by lower-than-expected U.S. consumable revenue, as well as a one-time cost associated with a voluntary field action.

Operating expenses in the fourth quarter of 2025 were $77.4 million, compared with $63.4 million in the prior year period. The increase in operating expenses reflects continued investment to support commercial expansion, innovation across our BPH platform technology and increased funding for our Water IV Prostate Cancer trial.

Net loss was $29.8 million for the fourth quarter of 2025, compared to a loss of $18.9 million in the prior year period. Adjusted EBITDA* was a loss of $19.0 million for the fourth quarter of 2025, compared to a loss of $10.3 million in the prior year period.

Cash, cash equivalents and restricted cash balances as of December 31, 2025, totaled $289.5 million.

Full Year 2025 Financial Results
Revenue for the full year 2025 was $308.1 million, an increase of 37% compared to the prior year period. The growth was primarily driven by increases in U.S. revenue attributable to system placements and increased handpieces sold.

Gross margin for full year 2025 was 64%, compared to 61% for the full year 2024. Gross margin improvement was primarily due to improved overhead absorption and favorable revenue mix of U.S. handpieces sold.

Operating expenses were $300.1 million for the full year 2025, compared to $233.7 million for the full year 2024, an increase of 28%. The increase was driven by increased sales and marketing expenses primarily to expand the commercial organization, and increased research and development and general and administrative expenses.

Net loss was $95.6 million for the full year 2025, compared to $91.4 million for the full year 2024. Adjusted EBITDA was a loss of $50.2 million for full year 2024, compared to a loss of $61.1 million for the full year 2024.

Full Year 2026 Financial Guidance
“Historically, handpiece unit sales exceeded procedure volumes by approximately 8% to 16%. Going forward, we expect handpiece unit sales and procedure volumes to be closely aligned,” said Larry Wood. “While annual U.S. procedure growth will be in the range of 39% to 48%, our decision to forecast procedure and handpiece volumes in close alignment has reduced our projected 2026 handpiece revenue guidance; however, this impact is meaningfully offset by higher handpiece prices of $3,500 per unit. Considering these factors, together with the short-term disruption associated with the sales force realignment, we are resetting our 2026 guidance to $390 to $410 million, representing annual growth of 27% to 33%. We believe these actions are essential to our long-term goals of sustained high growth and establishing a favorable financial profile.”

  • The Company expects revenue for the full year 2026 to be in the range of $390 million to $410 million, which represents growth of 27% to 33% compared to the prior year period
  • The Company expects full year 2026 U.S. procedure growth to be in the range of 39% to 48% compared to the prior year period
  • The Company expects full year 2026 gross margin to be approximately 65%
  • The Company expects full year 2026 operating expenses to be approximately $350 million
  • The Company expects full year 2026 adjusted EBITDA* loss to be in the range of $30 million to $17 million

First Quarter 2026 Financial Guidance

  • The Company expects total procedures for the first quarter of 2026 to be in the range of 12,000 to 12,800, which represents growth of 31% to 36% compared to the prior year period.
  • Total revenue for the first quarter of 2026 is expected to be in the range of $79 million to $82 million dollars, which represents growth of 14% to 19% to the prior year period.

*Adjusted EBITDA is a financial measure that is not prepared in accordance with generally accepted accounting principles in the United States (GAAP). For more information about the Company’s use of non-GAAP financial measures, please see the section below titled “Use of Non-GAAP Financial Measures (Unaudited).

Webcast and Conference Call Information
PROCEPT BioRobotics will host a conference call to discuss the fourth quarter 2025 financial results on Wednesday, February 25, 2026, at 4:30 p.m. Eastern Time.

Investors interested in listening to the conference call may do so by following one of the links below:

Investor Day in New York and Webcast
The Company will also host an in-person investor day event on Thursday, February 26, 2026, at the NASDAQ Headquarters in New York City beginning at 8:00am Eastern Time. A live, as well as an archived recording, will be available on the “Investors” section of the Company’s website at https://ir.procept-biorobotics.com.

About PROCEPT BioRobotics Corporation
PROCEPT BioRobotics’ mission is to revolutionize BPH treatment globally in partnership with urologists by delivering best-in-class robotic solutions that positively impact patients and drive value. PROCEPT BioRobotics manufactures the AQUABEAM® and HYDROS® Robotic Systems. The HYDROS Robotic System is the only AI-Powered, robotic technology that delivers Aquablation® therapy. PROCEPT BioRobotics designed Aquablation therapy to deliver effective, safe, and durable outcomes for males suffering from lower urinary tract symptoms or LUTS, due to BPH that are independent of prostate size and shape or surgeon experience. BPH is the most common prostate disease and impacts approximately 40 million men in the United States. The Company has developed a significant and growing body of clinical evidence with over 150 peer-reviewed publications, supporting the benefits and clinical advantages of Aquablation therapy.

Use of Non-GAAP Financial Measures (Unaudited)
This press release references Adjusted EBITDA, a financial measure that is not prepared in accordance with generally accepted accounting principles in the United States (GAAP). The Company defines Adjusted EBITDA as earnings before interest expense, taxes, depreciation and amortization and stock-based compensation. Non-GAAP financial measures are not a substitute for or superior to measures of financial performance prepared in accordance with GAAP and should not be considered as an alternative to any other performance measures derived in accordance with GAAP.

The Company believes that presenting Adjusted EBITDA provides useful supplemental information to investors about the Company in understanding and evaluating its operating results, enhancing the overall understanding of its past performance and future prospects, and allowing for greater transparency with respect to key financial metrics used by its management in financial and operational decision making. However, there are a number of limitations related to the use of non-GAAP measures and their nearest GAAP equivalents. For example, other companies may calculate non-GAAP measures differently, or may use other measures to calculate their financial performance, and therefore any non-GAAP measures the Company uses may not be directly comparable to similarly titled measures of other companies.

Forward Looking Statements
This release contains forward‐looking statements within the meaning of federal securities laws, including with respect to the Company’s projected financial performance for full year 2026, statements regarding the potential utilities, values, benefits and advantages of Aquablation therapy performed using PROCEPT BioRobotics’ products, including AquaBeam or Hydros Robotic Systems, which involve risks and uncertainties that could cause the actual results to differ materially from the anticipated results and expectations expressed in these forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements. Forward-looking statements are only predictions based on the Company’s current expectations, estimates, and assumptions, valid only as of the date they are made, and subject to risks and uncertainties, some of which the Company is not currently aware.   Forward-looking statements may include statements regarding financial guidance, market opportunity and penetration, procedure growth, the Company’s possible or assumed future results of operations, including descriptions of the Company’s revenues, gross margins, profitability, operating expenses, installed base growth, commercial momentum and overall business strategy. Forward‐looking statements should not be read as a guarantee of future performance or results and may not necessarily be accurate indications of the times at, or by, which such performance or results will be achieved. These forward‐looking statements are based on the Company’s current expectations and inherently involve significant risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in such forward‐looking statements as a result of these risks and uncertainties. These risks and uncertainties are described more fully in the section titled “Risk Factors” in the Company’s filings with the Securities and Exchange Commission (the “SEC”), including the Company’s annual report on Form 10-K filed with the SEC on February 27, 2025, and amended on April 11, 2025, and subsequent quarterly reports on Form 10-Q. PROCEPT BioRobotics does not undertake any obligation to update forward‐looking statements and expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward‐looking statements contained herein. These forward-looking statements should not be relied upon as representing PROCEPT BioRobotics’ views as of any date subsequent to the date of this press release.

Important Safety Information
All surgical treatments have inherent and associated side effects. For a list of potential side effects visit https://aquablation.com/safety-information/

Investor Contact:
Matt Bacso
VP, Investor Relations and Business Operations
m.bacso@procept-biorobotics.com

 
PROCEPT BioRobotics Corporation
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited, in thousands, except per share data)
 
    Three Months Ended
December 31,
  Twelve Months Ended
December 31,
      2025       2024       2025       2024  
Revenue   $ 76,383     $ 68,236     $ 308,054     $ 224,498  
Cost of sales     30,070       24,564       111,828       87,399  
Gross profit     46,313       43,672       196,226       137,099  
Operating expenses:                
Research and development     19,056       15,066       71,277       62,298  
Selling, general and administrative     58,298       48,316       228,808       171,415  
Total operating expenses     77,354       63,382       300,085       233,713  
Loss from operations     (31,041 )     (19,710 )     (103,859 )     (96,614 )
Interest expense     (894 )     (969 )     (3,586 )     (4,184 )
Interest and other income, net     2,280       2,191       12,063       9,753  
Loss before income taxes     (29,655 )     (18,488 )     (95,382 )     (91,045 )
Provision for income taxes     190       368       190       368  
Net loss   $ (29,845 )   $ (18,856 )   $ (95,572 )   $ (91,413 )
Net loss per share, basic and diluted   $ (0.53 )   $ (0.35 )   $ (1.72 )   $ (1.75 )
Weighted-average common shares used to                
Compute net loss per share attributable to                
Common shareholders, basic and diluted     56,071       55,838       55,544       52,125  

 
PROCEPT BioRobotics Corporation
RECONCILIATION OF GAAP NET LOSS TO ADJUSTED EBITDA
(Unaudited, in thousands)
 
    Three Months Ended
December 31,
  Twelve Months Ended
December 31,
      2025       2024       2025       2024  
Net loss   $ (29,845 )   $ (18,856 )   $ (95,572 )   $ (91,413 )
Depreciation and amortization expense     1,709       1,453       6,390       5,234  
Stock-based compensation expense     10,842       9,085       47,603       31,840  
Interest (income) and interest expense, net     (1,719 )     (2,017 )     (8,632 )     (6,711 )
Adjusted EBITDA   $ (19,013 )   $ (10,335 )   $ (50,211 )   $ (61,050 )

 
PROCEPT BioRobotics Corporation
RECONCILIATION OF GAAP NET LOSS TO ADJUSTED 2026 EBITDA Guidance
(Unaudited, in thousands)
 
    For the Year Ending
December 31, 2026
    LOW   HIGH
Net loss   $ (91,500 )   $ (78,500 )
Depreciation and amortization expense     7,500       7,500  
Stock-based compensation expense     59,000       59,000  
Interest (income) and interest expense, net     (5,000 )     (5,000 )
Adjusted EBITDA   $ (30,000 )   $ (17,000 )

 
PROCEPT BioRobotics Corporation
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited, in thousands)
 
    December 31, 2025   December 31, 2024
Assets        
Current assets:        
Cash and cash equivalents   $ 286,503     $ 333,725  
Accounts receivable, net     83,533       83,496  
Inventory     70,694       56,168  
Prepaid expenses and other current assets     9,648       8,453  
Total current assets     450,378       481,842  
Restricted cash, non-current     3,038       3,038  
Property and equipment, net     30,399       26,709  
Operating lease right-of-use assets, net     17,538       18,941  
Intangible assets, net     709       932  
Other assets     6,019       2,555  
Total assets   $ 508,081     $ 534,017  
         
Liabilities and Stockholders’ Equity        
Current liabilities:        
Accounts payable   $ 17,285     $ 10,032  
Accrued compensation     23,175       21,537  
Deferred revenue     13,048       9,565  
Operating leases, current     2,214       1,910  
Loan facility liability     —       2,000  
Other current liabilities     10,073       8,089  
Total current liabilities     65,795       53,133  
Long-term debt     51,615       51,472  
Operating leases, non-current     24,654       26,868  
Other liabilities     147       324  
Total liabilities     142,211       131,797  
         
Stockholders’ equity:        
Additional paid-in capital     1,007,390       948,091  
Accumulated other comprehensive gain     37       114  
Accumulated deficit     (641,557 )     (545,985 )
Total stockholders’ equity     365,870       402,220  
Total liabilities and stockholders’ equity   $ 508,081     $ 534,017  

                                 
PROCEPT BioRobotics Corporation
REVENUE BY TYPE AND GEOGRAPHY
(Unaudited, in thousands)

                                 
    Three Months Ended
December 31,
  Twelve Months Ended
December 31,
      2025       2024       2025       2024  
U.S.                        
System sales and rentals   $ 27,600     $ 27,636     $ 93,000     $ 78,614  
Handpieces and other consumables     34,001       29,325       159,669       110,542  
Service     4,986       3,428       17,709       11,316  
Total U.S. revenue     66,587       60,389       270,378       200,472  
Outside of U.S.                        
System sales and rentals     2,953       3,711       13,132       11,685  
Handpieces and other consumables     5,977       3,684       21,777       10,914  
Service     866       452       2,767       1,427  
Total outside of U.S. revenue     9,796       7,847       37,676       24,026  
Total revenue   $ 76,383     $ 68,236     $ 308,054     $ 224,498  
                         

 
PROCEPT BioRobotics Corporation
QUARTERLY U.S. INSTALL BASE AND PROCEDURES
(Unaudited, in thousands)
 
  Q1’23   Q2’23   Q3’23   Q4’23   Q1’24   Q2’24   Q3’24   Q4’24   Q1’25   Q2’25   Q3’25   Q4’25   FY 23   FY 24   FY 25
U.S. Install Base                                                          
Beginning install base 167   192   233   271   315   354   400   445   505   547   595   653   167   315   505
Systems placed 25   41   38   44   39   46   45   60   42   48   58   65   148   190   213
Ending install base 192   233   271   315   354   400   445   505   547   595   653   718   315   505   718
                                                           
U.S Procedures (000) 3.0   3.6   4.3   5.6   6.1   7.0   7.4   7.2   9.3   10.8   11.0   12.2   16.5   27.7   43.3

Celcuity To Participate in Upcoming Investor Conferences

Celcuity To Participate in Upcoming Investor Conferences




Celcuity To Participate in Upcoming Investor Conferences

MINNEAPOLIS, Feb. 25, 2026 (GLOBE NEWSWIRE) — Celcuity Inc. (Nasdaq: CELC), a clinical-stage biotechnology company pursuing development of targeted therapies for oncology, today announced that Brian Sullivan, Chief Executive Officer, and Co-founder of Celcuity, will present and be available for one-on-one investor meetings at the following investor conferences:

  • Jefferies Biotech on the Beach Summit; Wednesday, March 11, 2026. Management will host one-on-one investor meetings only.

Alternatively, the live webcasts will be accessible from the Investors section of the company’s website at https://ir.celcuity.com/events-presentations/ with a replay available shortly after the live events.

About Celcuity

Celcuity is a clinical-stage biotechnology company pursuing the development of targeted therapies for the treatment of multiple solid tumor indications. The company’s lead therapeutic candidate is gedatolisib, a potent, pan-PI3K and mTORC1/2 inhibitor that comprehensively blockades the PI3K/AKT/mTOR (“PAM”) pathway. Its mechanism of action and pharmacokinetic properties are differentiated from other currently approved and investigational therapies that target PI3Kα, AKT, or mTORC1 alone or together. A Phase 3 clinical trial, VIKTORIA-1, evaluating gedatolisib in combination with fulvestrant, with or without palbociclib, in patients with HR+/HER2- advanced breast cancer (“ABC”), has completed enrollment, and the company has reported detailed results for the PIK3CA wild-type cohort. A Phase 3 clinical trial, VIKTORIA-2, evaluating gedatolisib plus a CDK4/6 inhibitor and fulvestrant as first-line treatment for patients with HR+/HER2- ABC, is ongoing. A Phase 1/2 clinical trial, CELC-G-201, evaluating gedatolisib in combination with darolutamide in patients with metastatic castration resistant prostate cancer, is ongoing. More detailed information about Celcuity’s active clinical trials can be found at ClinicalTrials.gov. Celcuity is headquartered in Minneapolis. Further information about Celcuity can be found at www.celcuity.com. Follow us on LinkedIn and X.

Contacts: 

Celcuity Inc. 
Brian Sullivan, bsullivan@celcuity.com
Vicky Hahne, vhahne@celcuity.com  
(763) 392-0123  
Jodi Sievers, jsievers@celcuity.com
(415) 494-9924

Celcuity To Participate in Upcoming Investor Conferences

Celcuity To Participate in Upcoming Investor Conferences




Celcuity To Participate in Upcoming Investor Conferences

MINNEAPOLIS, Feb. 25, 2026 (GLOBE NEWSWIRE) — Celcuity Inc. (Nasdaq: CELC), a clinical-stage biotechnology company pursuing development of targeted therapies for oncology, today announced that Brian Sullivan, Chief Executive Officer, and Co-founder of Celcuity, will present and be available for one-on-one investor meetings at the following investor conferences:

  • Jefferies Biotech on the Beach Summit; Wednesday, March 11, 2026. Management will host one-on-one investor meetings only.

Alternatively, the live webcasts will be accessible from the Investors section of the company’s website at https://ir.celcuity.com/events-presentations/ with a replay available shortly after the live events.

About Celcuity

Celcuity is a clinical-stage biotechnology company pursuing the development of targeted therapies for the treatment of multiple solid tumor indications. The company’s lead therapeutic candidate is gedatolisib, a potent, pan-PI3K and mTORC1/2 inhibitor that comprehensively blockades the PI3K/AKT/mTOR (“PAM”) pathway. Its mechanism of action and pharmacokinetic properties are differentiated from other currently approved and investigational therapies that target PI3Kα, AKT, or mTORC1 alone or together. A Phase 3 clinical trial, VIKTORIA-1, evaluating gedatolisib in combination with fulvestrant, with or without palbociclib, in patients with HR+/HER2- advanced breast cancer (“ABC”), has completed enrollment, and the company has reported detailed results for the PIK3CA wild-type cohort. A Phase 3 clinical trial, VIKTORIA-2, evaluating gedatolisib plus a CDK4/6 inhibitor and fulvestrant as first-line treatment for patients with HR+/HER2- ABC, is ongoing. A Phase 1/2 clinical trial, CELC-G-201, evaluating gedatolisib in combination with darolutamide in patients with metastatic castration resistant prostate cancer, is ongoing. More detailed information about Celcuity’s active clinical trials can be found at ClinicalTrials.gov. Celcuity is headquartered in Minneapolis. Further information about Celcuity can be found at www.celcuity.com. Follow us on LinkedIn and X.

Contacts: 

Celcuity Inc. 
Brian Sullivan, bsullivan@celcuity.com
Vicky Hahne, vhahne@celcuity.com  
(763) 392-0123  
Jodi Sievers, jsievers@celcuity.com
(415) 494-9924

MIMEDX Announces Record Fourth Quarter and Full Year 2025 Operating and Financial Results

MIMEDX Announces Record Fourth Quarter and Full Year 2025 Operating and Financial Results




MIMEDX Announces Record Fourth Quarter and Full Year 2025 Operating and Financial Results

Net Sales Grew 27% Year-Over-Year for the Fourth Quarter and 20% for the Full Year

Fourth Quarter GAAP Net Income and Earnings Per Share were $15 million and $0.10, Respectively

Fourth Quarter Adjusted EBITDA1 was $29 Million, or 25% of Net Sales

Company Estimates 2026 Net Sales in a Range of $340-360 Million

Announces $100 Million Share Repurchase Program Authorization

Management to Host Conference Call Today, February 25, 2026, at 4:30 PM ET

MARIETTA, Ga., Feb. 25, 2026 (GLOBE NEWSWIRE) — MiMedx Group, Inc. (Nasdaq: MDXG) (“MIMEDX” or the “Company”), today announced operating and financial results for the fourth quarter and full year 2025.

Joseph H. Capper, MIMEDX Chief Executive Officer, commented, “MIMEDX delivered a record year of revenue and profitability in 2025, with fourth quarter results that included net sales growth of 27% year-over-year, net income of $15 million, an Adjusted EBITDA margin of 25% of net sales, and robust free cash flow. These results were driven by strong double-digit contributions in both Wound and Surgical, which grew 28% and 25%, respectively, reflecting exceptional commercial execution across the markets we serve. We were particularly pleased with the durable double-digit growth seen in Surgical, and we are keenly focused on the untapped clinical opportunities for our current and future products.”

Mr. Capper continued, “Looking ahead to 2026, the Company remains committed to providing a best-in-class portfolio of evidence-based, differentiated products to capitalize on the many opportunities in front of us. With the recent product additions to our Wound and Surgical offerings, I am as confident as ever in our ability to make significant headway this year in a variety of clinical settings.”

“The short-term disruptions caused by Medicare reimbursement changes in the Wound market will likely have an impact on our 2026 revenue. Once demand patterns normalize, we expect to gain significant volume over time. Meanwhile, we believe the clear momentum we have across the rest of our business — Surgical, international and Wound commercial pay — will provide continued profitability and cash flow. Thus, enabling us to maintain our leadership position over both the short- and long-term,” concluded Mr. Capper.

____________________
1 Adjusted EBITDA is a Non-GAAP Measure. This press release contains this and other Non-GAAP measures. For reconciliations of our Non-GAAP measures to their nearest GAAP measure, refer to the section titled “Reconciliation of Non-GAAP Measures” below.

Fourth Quarter and Full Year 2025 Results Discussion

Net Sales

MIMEDX reported net sales for the three months ended December 31, 2025 of $118 million, compared to $93 million for the three months ended December 31, 2024, an increase of 27%. The increase was driven by Wound product sales growth of 28%, which reflected the introduction of EPIXPRESS® as well as the contribution from EMERGE™ during the quarter. Additionally, fourth quarter Surgical sales grew 25% and represented the sixth consecutive quarter of sequential sales growth for this product category, led by sustained momentum for AMNIOFIX® and AMNIOEFFECT® as well as another strong performance for the Company’s particulate portfolio.

For the full year 2025 MIMEDX reported net sales of $419 million, compared to $349 million in the prior year period, reflecting growth of 20%. On a full year basis, Wound growth of 20% was led by sales of new products, including CELERA™, EMERGE, and EPIXPRESS, which more than offset pressure from lower-priced products. Also in 2025, Surgical net sales rose 21% compared to the prior year period, with strong contributions from AMNIOFIX, AMNIOEFFECT and HELIOGEN®.

Gross Profit and Margin

Gross profit for the three months ended December 31, 2025, was $99 million, an increase of $23 million as compared to the prior year period. Gross margin for the three months ended December 31, 2025 was 84%, compared to 82% in the prior year period. The increase was driven by favorable product mix. On an adjusted basis, fourth quarter 2025 gross margin was 86%, which reflects a roughly flat adjusted gross margin compared to the prior year period.

For the full year 2025, gross profit was $346 million, reflecting an increase of $57 million compared to the prior year period. Additionally, gross margin for the full year 2025 was 83%, flat compared to the full year 2024. On an adjusted basis, gross margin for the full year 2025 was 86% compared to 84% for the full year 2024.

Operating Expenses

Selling, general and administrative (“SG&A”) expenses for the three months ended December 31, 2025, were $73 million compared to $61 million for the three months ended December 31, 2024. For the full year 2025, SG&A expenses totaled $266 million, compared to $225 million for the prior period, reflecting a year over year increase of 18%. For both the fourth quarter and full year 2025, the year-over-year increase in SG&A was driven primarily by higher commissions.

Research and development (“R&D”) expenses for the three months ended December 31, 2025, were $5 million compared to $4 million for the three months ended December 31, 2024. For the full year 2025, research and development expenses totaled $15 million, compared to $12 million for 2024. R&D spend in the quarter and year was driven, in part, by the randomized controlled trial for EPIEFFECT and ongoing investments in the development of future products in our pipeline.

Net income for the three months and full year ended December 31, 2025 was $15 million and $49 million, respectively, compared to a net income of $7 million and $42 million for the three months and full year ended December 31, 2024, respectively.

Cash and Cash Equivalents

As of December 31, 2025, the Company had $166 million of cash and cash equivalents compared to $104 million as of December 31, 2024 and $142 million as of September 30, 2025. As of December 31, 2025, our cash position, net of debt on our balance sheet, was $148 million, representing a sequential increase of $24 million and an increase of $63 million for the year.

Share Repurchase Authorization Announced

Also today, the MIMEDX Board of Directors has authorized a share repurchase program of up to $100 million of the Company’s common stock over a two-year period.   The share repurchase program provides MIMEDX with the flexibility to purchase shares of its common stock in the open market or in privately negotiated transactions, subject to market conditions and other factors.

MIMEDX intends to use the repurchase program periodically on a discretionary basis, subject to general business and market conditions and balanced against other investment opportunities. The repurchase program may be commenced, suspended or discontinued at any time.

MIMEDX remains focused on executing its strategic priorities and its decision to establish this repurchase program reflects its balanced approach to capital allocation.  

Financial Outlook

For 2026, MIMEDX currently estimates net sales to be in a range of $340 to $360 million and for adjusted EBITDA margin to be in the mid-to-high teens.

Longer-term, the Company continues to expect to achieve annual net sales growth in the low double-digits as a percentage with an Adjusted EBITDA margin above 20%.

Conference Call and Webcast

MIMEDX will host a conference call and webcast to review its fourth quarter and full year 2025 results on Wednesday, February 25, 2026, beginning at 4:30 p.m., Eastern Time. The call can be accessed using the following information:

Webcast: Click here
U.S. Investors: 877-407-6184
International Investors: 201-389-0877
Conference ID: 13758446

A replay of the webcast will be available for approximately 30 days on the Company’s website at www.mimedx.com following the conclusion of the event.

Important Cautionary Statement

This press release and our investor conference call include forward-looking statements, which reflect management’s current beliefs and expectations regarding future events and operating performance and speak only as of the date hereof. These forward-looking statements are not guarantees of future performance and involve a number of risks and uncertainties. These statements include statements regarding: (i) future sales, sales growth, and Adjusted EBITDA margin; (ii) our longer term financial goals and expectations for future financial results, including levels of net sales, Adjusted EBITDA, and Adjusted EBITDA margin; (iii) our expectations regarding the size of the market for our products;(iv) our expectations regarding the impact of CMS’ updated 2026 Medicare reimbursement rules and model and our belief that Medicare is likely to introduce national coverage policy, given the withdrawal of the LCDs; (v) continued growth in different care settings and different products, specifically accounting for the change caused by CMS’ updated 2026 reimbursement rules and model; and (vi) our expected outcomes relating to improving workflow and strengthening bonds between the Company and its customers. Additional forward-looking statements may be identified by words such as “believe,” “expect,” “may,” “plan,” “goal,” “outlook,” “potential,” “will,” “preliminary,” and similar expressions, and are based on management’s current beliefs and expectations.

Forward-looking statements are subject to risks and uncertainties, and the Company cautions investors against placing undue reliance on such statements. Actual results may differ materially from those set forth in the forward-looking statements. Factors that could cause actual results to differ from expectations include: (i) future sales are uncertain and are affected by competition, access to customers, patient access to healthcare providers, the reimbursement environment, particularly in light of CMS’ updated 2026 Medicare spending rules and reimbursement model, and many other factors; (ii) the Company may change its plans due to unforeseen circumstances; (iii) the results of scientific research are uncertain and may have little or no value; (iv) our ability to sell our products in other countries depends on a number of factors including adequate levels of reimbursement, market acceptance of novel therapies, and our ability to build and manage a direct sales force or third party distribution relationship; (v) the effectiveness of amniotic tissue as a therapy for particular indications or conditions is the subject of further scientific and clinical studies; (vi) we may alter the timing and amount of planned expenditures for research and development based on regulatory developments; (vii) the impact of CMS’ updated 2026 spending rules and reimbursement model, particularly the shift to a capped rate for Medicare reimbursement, including the impact on our product utilization given the potential shift to alternate treatment modalities; and (viii) changes in the size of the addressable market for our products. Additional factors that could impact outcomes and our results include those described in the Risk Factors section of our Annual Report on Form 10-K and our Quarterly Reports on Form 10-Q. filed with the Securities and Exchange Commission. Any forward-looking statements speak only as of the date of this press release and the Company assumes no obligation to update any forward-looking statement.

About MIMEDX

MIMEDX is a pioneer and leader focused on helping humans heal. With more than a decade and a half of helping clinicians manage chronic and other hard-to-heal wounds, MIMEDX provides a leading portfolio of products for applications in the wound care, burn, and surgical sectors of healthcare. The Company’s vision is to be the leading global provider of healing solutions through relentless innovation to restore quality of life. For additional information, please visit www.mimedx.com.

Contact:
Matt Notarianni
Investor Relations
470.304.7291
mnotarianni@mimedx.com


Selected Unaudited Financial Information

MiMedx Group, Inc.
Condensed Consolidated Balance Sheets
(in thousands) Unaudited
  December 31,
    2025       2024  
ASSETS      
Current assets:      
Cash and cash equivalents $ 166,121     $ 104,416  
Accounts receivable, net   75,707       55,828  
Inventory   25,340       23,807  
Other current assets   10,303       7,835  
Total current assets   277,471       191,886  
Property and equipment, net   4,713       5,944  
Deferred tax assets   19,596       28,306  
Goodwill   19,441       19,441  
Intangible assets, net   14,158       11,626  
Other assets   7,274       6,712  
Total assets $ 342,653     $ 263,915  
LIABILITIES AND STOCKHOLDERS’ EQUITY      
Current liabilities:      
Current portion of long term debt $ 1,500     $ 1,000  
Accounts payable   14,528       7,409  
Accrued compensation   31,065       23,667  
Accrued expenses   11,383       9,012  
Other current liabilities   5,790       4,507  
Total current liabilities   64,266       45,595  
Long term debt, net   16,467       17,830  
Other liabilities   5,372       7,383  
Total liabilities $ 86,105     $ 70,808  
Stockholders’ equity      
Common stock; $.001 par value; 250,000,000 shares authorized, 148,093,920 issued and outstanding at December 31, 2025 and 146,932,032 issued and outstanding at December 31, 2024   148       147  
Additional paid-in capital   299,081       284,219  
Accumulated deficit   (42,681 )     (91,259 )
Total stockholders’ equity   256,548       193,107  
Total liabilities and stockholders’ equity $ 342,653     $ 263,915  
       

MiMedx Group, Inc.
Condensed Consolidated Statements of Operations
(in thousands, except share and per share amounts) Unaudited
  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net sales $ 118,095     $ 92,907     $ 418,630     $ 348,879  
Cost of sales   19,055       16,909       73,013       60,073  
Gross profit   99,040       75,998       345,617       288,806  
               
Operating expenses:              
Selling, general and administrative   73,073       61,043       266,194       225,087  
Research and development   4,761       3,571       15,097       12,341  
Investigation, restatement and related   —       43       —       (8,698 )
Amortization of intangible assets   128       194       439       765  
Impairment of intangible assets   —       94       —       446  
Operating income   21,078       11,053       63,887       58,865  
               
Other income (expense), net              
Interest income (expense), net   904       403       2,933       (1,006 )
Other expense, net   (186 )     (208 )     (558 )     (565 )
Income from continuing operations before income tax   21,796       11,248       66,262       57,294  
Income tax provision (expense) benefit from continuing operations   (6,605 )     (3,811 )     (17,684 )     (15,296 )
Net income from continuing operations   15,191       7,437       48,578       41,998  
Income (loss) from discontinued operations, net of tax   —       —       —       421  
Net income $ 15,191     $ 7,437     $ 48,578     $ 42,419  
Net income available to common stockholders from continuing operations $ 15,191     $ 7,437     $ 48,578     $ 41,998  
               
Basic net income (loss) per common share:              
Continuing operations $ 0.10     $ 0.05     $ 0.33     $ 0.29  
Discontinued operations   —       —       —       —  
Basic net income per common share: $ 0.10     $ 0.05     $ 0.33     $ 0.29  
               
Diluted net income (loss) per common share:              
Continuing operations $ 0.10     $ 0.05     $ 0.32     $ 0.28  
Discontinued operations   —       —       —       —  
Diluted net income (loss) per common share: $ 0.10     $ 0.05     $ 0.32     $ 0.28  
               
Weighted average common shares outstanding – basic   148,091,670       147,008,235       147,793,069       146,979,354  
Weighted average common shares outstanding – diluted   150,189,160       149,242,415       149,724,507       149,049,197  
                               

MiMedx Group, Inc.
Condensed Consolidated Statements of Cash Flows
(in thousands) Unaudited
  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net cash flows provided by operating activities $ 24,956     $ 18,782     $ 74,003     $ 66,198  
Net cash flows used in investing activities   (335 )     (2,767 )     (6,886 )     (9,583 )
Net cash flows used in financing activities   (583 )     (400 )     (5,412 )     (34,199 )
Net change in cash $ 24,038     $ 15,615     $ 61,705     $ 22,416  
                               

Reconciliation of Non-GAAP Measures

In addition to our GAAP results, we provide certain non-GAAP measures including Adjusted EBITDA, related margins, Free Cash Flow, Adjusted Gross Profit, Adjusted Gross Margin and Adjusted Net Income. We believe that the presentation of these measures provides important supplemental information to management and investors regarding our performance. These measures are not a substitute for GAAP measures. Company management uses these non-GAAP measures as aids in monitoring our ongoing financial performance from quarter-to-quarter and year-to-year on a regular basis and for benchmarking against comparable companies.

These non-GAAP financial measures reflect the exclusion of the following items:

  • Share-based compensation expense – expense recognized related to awards to employees and our board of directors pursuant to our share-based compensation plans. This expense is reflected amongst cost of sales, research and development expense, and selling, general, and administrative expense in the consolidated statements of operations.
  • Investigation, restatement, and related (benefit) expense – expenses incurred toward the legal defense of the Company and advanced on behalf of certain former officers and directors, net of negotiated reductions and settlements of amounts previously advanced, related to certain legal matters. This expense is reflected in the line of the same name in our consolidated statements of operations.
  • Impairment of intangible assets – reflects the impairment of intangibles. This expense is reflected in the line of the same name in our consolidated statements of operations.
  • Transaction-related expenses – reflects expenses incrementally incurred resulting from the consummation of material strategic transactions or the integration of acquired assets or operations into our core business.
  • Strategic legal and regulatory expenses – With respect to the three months and year ended December 31, 2025, this relates to litigation and regulatory expenses. Litigation expenses incurred relate to suits filed against former employees and their employers for violation of non-compete and non-solicitation agreements and related matters. Regulatory expenses relate to legal fees incurred stemming from action taken against the United States Food & Drug Administration (“FDA”) surrounding the designation of one of our products.
  • Loss on extinguishment of debt – reflects the excess of cash paid to extinguish debt over the carrying value of the debt on our balance sheet upon the repayment and termination of a loan agreement. With respect to the year ended December 31, 2025, this relates to the repayment and termination of the Company’s loan agreement with Hayfin. Amounts in this line reflect (i) prepayment premium paid and (ii) write-offs of unamortized original issue discount and deferred financing costs.
  • Expenses related to the Disbanding of Regenerative Medicine – incremental expenses recognized or incurred directly as a result of our announcement to disband our Regenerative Medicine segment.
  • Amortization of acquired intangible assets – reflects amortization expense recognized solely related to assets which were acquired as part of a transaction. These expenses are reflected in cost of sales in our consolidated statements of operations.
  • Reorganization expenses – reflects severance expense arising from the enactment of various strategic initiatives, including separations from certain officers of the Company.
  • Income Tax Adjustment – for purposes of calculating Adjusted Net Income and Adjusted Earnings Per Share, reflects our expectation of a long-term effective tax rate, which is normalized and balance sheet-agnostic. Actual reporting tax expense will be based on GAAP earnings, and may differ from the expected long-term effective tax rate due to a variety of factors, including the tax treatment of various transactions included in GAAP net income and other reconciling items that are excluded in determining Adjusted Net Income and Adjusted EPS. The actual long-term normalized effective tax rate was 25% for each of the years ended December 31, 2025 and 2024.

Adjusted EBITDA and Adjusted EBITDA margin

Adjusted EBITDA consists of GAAP net income excluding: (i) share-based compensation, (ii) income tax provision, (iii) amortization of intangible assets, (iv) strategic legal and regulatory expenses, (v) interest (income) expense, net, (vi) depreciation expense, (vii) reorganization expenses, (viii) transaction-related expenses, (ix) investigation, restatement and related expense (benefit), (x) impairment of intangible assets, and (xi) expenses related to disbanding of the Regenerative Medicine business unit.

A reconciliation of GAAP net income to Adjusted EBITDA appears in the table below (dollars in thousands):

  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net Income $ 15,191     $ 7,437     $ 48,578     $ 42,419  
Non-GAAP Adjustments:              
Share-based compensation   2,463       4,693       16,396       16,933  
Income tax provision   6,605       3,811       17,684       15,296  
Amortization of intangible assets   2,648       2,426       12,617       3,762  
Strategic legal and regulatory expenses   2,494       1,140       9,185       2,806  
Interest (income) expense, net   (904 )     (403 )     (2,933 )     1,006  
Depreciation expense   572       564       2,264       2,279  
Reorganization expense   203       —       1,029       —  
Transaction related expenses   103       (38 )     902       612  
Investigation, restatement and related expenses   —       44       —       (8,698 )
Impairment of intangible assets   —       94       —       446  
Expenses related to disbanding of Regenerative Medicine business unit   —       —       —       (421 )
Adjusted EBITDA $ 29,375     $ 19,768     $ 105,722     $ 76,440  
Adjusted EBITDA margin   24.9 %     21.3 %     25.3 %     21.9 %


Adjusted Net Income and Adjusted Gross Margin

Adjusted Net Income provides a view of our operating performance, exclusive of certain items which are non-recurring or not reflective of our core operations.

Adjusted Net Income is defined as GAAP net income plus (i) amortization of acquired intangible assets, (ii) strategic legal and regulatory expenses, (iii) transaction-related expenses, (iv) reorganization expenses, (v) investigation, restatement and related expense (benefit), (vi) impairment of intangible assets, (vii) loss on extinguishment of debt, (viii) expenses related to disbanding of Regenerative Medicine business unit, and (ix) the long-term effective income tax rate adjustment.

Each of the adjustments to reconcile Adjusted Net Income to GAAP net income affect individual financial statement captions which are reflected in our consolidated statements of operations, including gross profit. Adjusted Gross Profit is therefore defined as GAAP gross profit plus (i) amortization of acquired intangible assets, (ii) strategic legal and regulatory expenses, (iii) transaction-related expenses, (iv) reorganization expenses, (v) investigation, restatement and related expense (benefit), (vi) impairment of intangible assets, (vii) loss on extinguishment of debt, (viii) expenses related to disbanding of Regenerative Medicine business unit, and (ix) the long-term effective income tax rate adjustment
to the extent that these adjustments impact GAAP gross profit. Adjusted Gross Margin is calculated as Adjusted Gross Profit divided by GAAP net sales.
A reconciliation of GAAP net income to Adjusted Net Income appears in the table below (in thousands):

  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net income $ 15,191     $ 7,437     $ 48,578     $ 42,419  
Amortization of acquired intangible assets   2,519       2,232       12,178       2,997  
Strategic legal and regulatory expenses   2,494       1,140       9,185       2,806  
Transaction related expenses   103       (38 )     902       612  
Reorganization expense   203       —       1,029       —  
Investigation, restatement and related expense (benefit)   —       43       —       (8,698 )
Impairment of intangible assets   —       94       —       446  
Loss on extinguishment of debt   —       —       —       1,401  
Expenses related to disbanding of Regenerative Medicine business unit   —       —       —       (421 )
Long-term effective income tax rate adjustment   (174 )     130       (4,705 )     1,082  
Adjusted net income $ 20,336     $ 11,038     $ 67,167     $ 42,644  

A reconciliation of various line items included in our GAAP unaudited condensed consolidated statements of operations to Adjusted Net Income, including Adjusted Gross Profit for the three months and years ended December 31, 2025 and 2024 are presented in the tables below (in thousands):

  Three months ended December 31, 2025
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 99,040     $ 73,073     $ 4,761   $ 15,191  
Amortization of acquired intangible assets   2,519       —       —     2,519  
Strategic legal and regulatory expenses   —       (2,494 )     —     2,494  
Reorganization expense       (203 )         203  
Transaction-related expenses   —       (90 )     —     103  
Long-term effective income tax rate adjustment   —       —       —     (174 )
Non-GAAP Measure $ 101,559     $ 70,286     $ 4,761   $ 20,336  
               
Reported Gross Profit Margin   83.9 %            
Adjusted Gross Profit Margin   86.0 %            

  Three months ended December 31, 2024
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 75,998     $ 61,043     $ 3,571   $ 7,437  
Investigation, restatement and related expenses   —       —       —     43  
Impairment of intangible assets   —       —       —     94  
Amortization of acquired intangible assets   2,232       —       —     2,232  
Transaction-related expenses   —       (30 )     —     (38 )
Strategic legal and regulatory expenses   —       (1,140 )     —     1,140  
Long-term effective income tax rate adjustment   —       —       —     130  
Non-GAAP Measure $ 78,230     $ 59,873     $ 3,571   $ 11,038  
               
Reported Gross Profit Margin   81.8 %            
Adjusted Gross Profit Margin   84.2 %            

  Year Ended December 31, 2025
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 345,617     $ 266,194     $ 15,097   $ 48,578  
Amortization of acquired intangible assets   12,178       —       —     12,178  
Strategic legal and regulatory expenses   —       (9,185 )     —     9,185  
Transaction-related expenses   —       (779 )     —     902  
Reorganization expense   —       (1,029 )     —     1,029  
Long-term effective income tax rate adjustment   —       —       —     (4,705 )
Non-GAAP Measure $ 357,795     $ 255,201     $ 15,097   $ 67,167  
               
Reported Gross Profit Margin   82.6 %            
Adjusted Gross Profit Margin   85.5 %            

  Year Ended December 31, 2024
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 288,806     $ 225,087     $ 12,341     42,419  
Loss on extinguishment of debt   —       —       —     1,401  
Investigation, restatement and related expenses   —       —       —     (8,698 )
Impairment of intangible assets   —       —       —     446  
Amortization of acquired intangible assets   2,997       —       —     2,997  
Transaction-related expenses   —       (551 )     —     612  
Strategic legal and regulatory expenses   —       (2,806 )     —     2,806  
Expenses related to disbanding of Regenerative Medicine Business Unit   —       —       —     (421 )
Long-term effective income tax rate adjustment   —       —       —     1,082  
Non-GAAP Measure $ 291,803     $ 221,730     $ 12,341   $ 42,644  
               
Reported Gross Profit Margin   82.8 %            
Adjusted Gross Profit Margin   83.6 %            


Adjusted Earnings Per Share

Adjusted Earnings Per Share is intended to provide a normalized view of earnings per share by removing items that may be irregular, one-time, or non-recurring from net income. This enables us to identify underlying trends in our business that could otherwise be masked by such items. Adjusted Earnings Per Share consists of GAAP diluted net income per common share including adjustments for: (i) amortization of acquired intangible assets, (ii) strategic legal and regulatory expenses, (iii) transaction-related expenses, (iv) reorganization expenses, (v) investigation, restatement and related expense (benefit), (vi) impairment of intangible assets, (vii) loss on extinguishment of debt, (viii) expenses related to disbanding of Regenerative Medicine business unit, and (ix) the long-term effective income tax rate adjustment. The effect of antidilution reflects the changes resulting from the removal of the dilutive impact of convertible securities which were dilutive for purposes of calculating GAAP net income per common share, but are antidilutive for non-GAAP purposes.

A reconciliation of GAAP diluted earnings per share to Adjusted Earnings Per Share appears in the table below (per diluted share):

  Three Months Ended December 31,   Year Ended December 31,
    2025     2024     2025       2024  
GAAP net income (loss) per common share – diluted $ 0.10   $ 0.05   $ 0.32     $ 0.28  
Loss on extinguishment of debt   0.00     0.00     0.00       0.01  
Investigation, restatement and related (benefit) expense   0.00     0.00     0.00       (0.06 )
Impairment of intangible assets   0.00     0.00     0.00       0.00  
Amortization of acquired intangible assets   0.02     0.01     0.08       0.02  
Transaction related expenses   0.00     0.00     0.01       0.00  
Strategic legal and regulatory expenses   0.02     0.01     0.06       0.02  
Expenses related to disbanding of Regenerative Medicine business unit   0.00     0.00     0.00       0.00  
Reorganization expenses   0.00     0.00     0.01       0.00  
Long-term effective income tax rate adjustment   0.00     0.00     (0.03 )     0.01  
Adjusted Earnings Per Share $ 0.14   $ 0.07   $ 0.45     $ 0.28  
               
Weighted average common shares outstanding – adjusted   150,189,160     149,242,415     149,724,507       149,049,197  


Free Cash Flow

Free Cash Flow is intended to provide a measure of our ability to generate cash in excess of capital investments. It provides management with a view of cash flows which can be used to finance operational and strategic investments.

Free Cash Flow is defined as net cash provided by operating activities less capital expenditures, including purchases of equipment.

A reconciliation of GAAP net cash flows provided by operating activities to Free Cash Flow appears in the table below (in thousands):

  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net cash flows provided by operating activities $ 24,956     $ 18,782       74,003       66,198  
Capital expenditures, including purchases of equipment   (285 )     (263 )     (1,033 )     (1,683 )
Free Cash Flow $ 24,671     $ 18,519     $ 72,970     $ 64,515  


Other Information

Net Sales by Product Category by Quarter

Below is a summary of net sales by product category (in thousands):

    2025     2024
  Q1   Q2   Q3   Q4   Q1   Q2   Q3   Q4
Wound $ 56,073   $ 64,476   $ 77,098   $ 78,679   $ 57,049   $ 57,547   $ 55,052   $ 61,357
Surgical   32,132     34,129     36,627     39,416     27,660     29,660     29,005     31,550
Net sales $ 88,205   $ 98,605   $ 113,725   $ 118,095   $ 84,709   $ 87,207   $ 84,057   $ 92,907


Selling, General and Administrative

Below is the breakout of selling, general and administrative expense by selling and marketing and general and administrative (in thousands):

    2025     2024
  Q1   Q2   Q3   Q4   Q1   Q2   Q3   Q4
Selling and marketing $ 46,861   $ 47,867   $ 53,720   $ 61,233   $ 44,477   $ 41,725   $ 41,721   $ 47,638
General and administrative   13,108     16,284     15,281     11,840     10,652     13,676     11,795     13,403
Selling, general and administrative $ 59,969   $ 64,151   $ 69,001   $ 73,073   $ 55,129   $ 55,401   $ 53,516   $ 61,041

MIMEDX Announces Record Fourth Quarter and Full Year 2025 Operating and Financial Results

MIMEDX Announces Record Fourth Quarter and Full Year 2025 Operating and Financial Results




MIMEDX Announces Record Fourth Quarter and Full Year 2025 Operating and Financial Results

Net Sales Grew 27% Year-Over-Year for the Fourth Quarter and 20% for the Full Year

Fourth Quarter GAAP Net Income and Earnings Per Share were $15 million and $0.10, Respectively

Fourth Quarter Adjusted EBITDA1 was $29 Million, or 25% of Net Sales

Company Estimates 2026 Net Sales in a Range of $340-360 Million

Announces $100 Million Share Repurchase Program Authorization

Management to Host Conference Call Today, February 25, 2026, at 4:30 PM ET

MARIETTA, Ga., Feb. 25, 2026 (GLOBE NEWSWIRE) — MiMedx Group, Inc. (Nasdaq: MDXG) (“MIMEDX” or the “Company”), today announced operating and financial results for the fourth quarter and full year 2025.

Joseph H. Capper, MIMEDX Chief Executive Officer, commented, “MIMEDX delivered a record year of revenue and profitability in 2025, with fourth quarter results that included net sales growth of 27% year-over-year, net income of $15 million, an Adjusted EBITDA margin of 25% of net sales, and robust free cash flow. These results were driven by strong double-digit contributions in both Wound and Surgical, which grew 28% and 25%, respectively, reflecting exceptional commercial execution across the markets we serve. We were particularly pleased with the durable double-digit growth seen in Surgical, and we are keenly focused on the untapped clinical opportunities for our current and future products.”

Mr. Capper continued, “Looking ahead to 2026, the Company remains committed to providing a best-in-class portfolio of evidence-based, differentiated products to capitalize on the many opportunities in front of us. With the recent product additions to our Wound and Surgical offerings, I am as confident as ever in our ability to make significant headway this year in a variety of clinical settings.”

“The short-term disruptions caused by Medicare reimbursement changes in the Wound market will likely have an impact on our 2026 revenue. Once demand patterns normalize, we expect to gain significant volume over time. Meanwhile, we believe the clear momentum we have across the rest of our business — Surgical, international and Wound commercial pay — will provide continued profitability and cash flow. Thus, enabling us to maintain our leadership position over both the short- and long-term,” concluded Mr. Capper.

____________________
1 Adjusted EBITDA is a Non-GAAP Measure. This press release contains this and other Non-GAAP measures. For reconciliations of our Non-GAAP measures to their nearest GAAP measure, refer to the section titled “Reconciliation of Non-GAAP Measures” below.

Fourth Quarter and Full Year 2025 Results Discussion

Net Sales

MIMEDX reported net sales for the three months ended December 31, 2025 of $118 million, compared to $93 million for the three months ended December 31, 2024, an increase of 27%. The increase was driven by Wound product sales growth of 28%, which reflected the introduction of EPIXPRESS® as well as the contribution from EMERGE™ during the quarter. Additionally, fourth quarter Surgical sales grew 25% and represented the sixth consecutive quarter of sequential sales growth for this product category, led by sustained momentum for AMNIOFIX® and AMNIOEFFECT® as well as another strong performance for the Company’s particulate portfolio.

For the full year 2025 MIMEDX reported net sales of $419 million, compared to $349 million in the prior year period, reflecting growth of 20%. On a full year basis, Wound growth of 20% was led by sales of new products, including CELERA™, EMERGE, and EPIXPRESS, which more than offset pressure from lower-priced products. Also in 2025, Surgical net sales rose 21% compared to the prior year period, with strong contributions from AMNIOFIX, AMNIOEFFECT and HELIOGEN®.

Gross Profit and Margin

Gross profit for the three months ended December 31, 2025, was $99 million, an increase of $23 million as compared to the prior year period. Gross margin for the three months ended December 31, 2025 was 84%, compared to 82% in the prior year period. The increase was driven by favorable product mix. On an adjusted basis, fourth quarter 2025 gross margin was 86%, which reflects a roughly flat adjusted gross margin compared to the prior year period.

For the full year 2025, gross profit was $346 million, reflecting an increase of $57 million compared to the prior year period. Additionally, gross margin for the full year 2025 was 83%, flat compared to the full year 2024. On an adjusted basis, gross margin for the full year 2025 was 86% compared to 84% for the full year 2024.

Operating Expenses

Selling, general and administrative (“SG&A”) expenses for the three months ended December 31, 2025, were $73 million compared to $61 million for the three months ended December 31, 2024. For the full year 2025, SG&A expenses totaled $266 million, compared to $225 million for the prior period, reflecting a year over year increase of 18%. For both the fourth quarter and full year 2025, the year-over-year increase in SG&A was driven primarily by higher commissions.

Research and development (“R&D”) expenses for the three months ended December 31, 2025, were $5 million compared to $4 million for the three months ended December 31, 2024. For the full year 2025, research and development expenses totaled $15 million, compared to $12 million for 2024. R&D spend in the quarter and year was driven, in part, by the randomized controlled trial for EPIEFFECT and ongoing investments in the development of future products in our pipeline.

Net income for the three months and full year ended December 31, 2025 was $15 million and $49 million, respectively, compared to a net income of $7 million and $42 million for the three months and full year ended December 31, 2024, respectively.

Cash and Cash Equivalents

As of December 31, 2025, the Company had $166 million of cash and cash equivalents compared to $104 million as of December 31, 2024 and $142 million as of September 30, 2025. As of December 31, 2025, our cash position, net of debt on our balance sheet, was $148 million, representing a sequential increase of $24 million and an increase of $63 million for the year.

Share Repurchase Authorization Announced

Also today, the MIMEDX Board of Directors has authorized a share repurchase program of up to $100 million of the Company’s common stock over a two-year period.   The share repurchase program provides MIMEDX with the flexibility to purchase shares of its common stock in the open market or in privately negotiated transactions, subject to market conditions and other factors.

MIMEDX intends to use the repurchase program periodically on a discretionary basis, subject to general business and market conditions and balanced against other investment opportunities. The repurchase program may be commenced, suspended or discontinued at any time.

MIMEDX remains focused on executing its strategic priorities and its decision to establish this repurchase program reflects its balanced approach to capital allocation.  

Financial Outlook

For 2026, MIMEDX currently estimates net sales to be in a range of $340 to $360 million and for adjusted EBITDA margin to be in the mid-to-high teens.

Longer-term, the Company continues to expect to achieve annual net sales growth in the low double-digits as a percentage with an Adjusted EBITDA margin above 20%.

Conference Call and Webcast

MIMEDX will host a conference call and webcast to review its fourth quarter and full year 2025 results on Wednesday, February 25, 2026, beginning at 4:30 p.m., Eastern Time. The call can be accessed using the following information:

Webcast: Click here
U.S. Investors: 877-407-6184
International Investors: 201-389-0877
Conference ID: 13758446

A replay of the webcast will be available for approximately 30 days on the Company’s website at www.mimedx.com following the conclusion of the event.

Important Cautionary Statement

This press release and our investor conference call include forward-looking statements, which reflect management’s current beliefs and expectations regarding future events and operating performance and speak only as of the date hereof. These forward-looking statements are not guarantees of future performance and involve a number of risks and uncertainties. These statements include statements regarding: (i) future sales, sales growth, and Adjusted EBITDA margin; (ii) our longer term financial goals and expectations for future financial results, including levels of net sales, Adjusted EBITDA, and Adjusted EBITDA margin; (iii) our expectations regarding the size of the market for our products;(iv) our expectations regarding the impact of CMS’ updated 2026 Medicare reimbursement rules and model and our belief that Medicare is likely to introduce national coverage policy, given the withdrawal of the LCDs; (v) continued growth in different care settings and different products, specifically accounting for the change caused by CMS’ updated 2026 reimbursement rules and model; and (vi) our expected outcomes relating to improving workflow and strengthening bonds between the Company and its customers. Additional forward-looking statements may be identified by words such as “believe,” “expect,” “may,” “plan,” “goal,” “outlook,” “potential,” “will,” “preliminary,” and similar expressions, and are based on management’s current beliefs and expectations.

Forward-looking statements are subject to risks and uncertainties, and the Company cautions investors against placing undue reliance on such statements. Actual results may differ materially from those set forth in the forward-looking statements. Factors that could cause actual results to differ from expectations include: (i) future sales are uncertain and are affected by competition, access to customers, patient access to healthcare providers, the reimbursement environment, particularly in light of CMS’ updated 2026 Medicare spending rules and reimbursement model, and many other factors; (ii) the Company may change its plans due to unforeseen circumstances; (iii) the results of scientific research are uncertain and may have little or no value; (iv) our ability to sell our products in other countries depends on a number of factors including adequate levels of reimbursement, market acceptance of novel therapies, and our ability to build and manage a direct sales force or third party distribution relationship; (v) the effectiveness of amniotic tissue as a therapy for particular indications or conditions is the subject of further scientific and clinical studies; (vi) we may alter the timing and amount of planned expenditures for research and development based on regulatory developments; (vii) the impact of CMS’ updated 2026 spending rules and reimbursement model, particularly the shift to a capped rate for Medicare reimbursement, including the impact on our product utilization given the potential shift to alternate treatment modalities; and (viii) changes in the size of the addressable market for our products. Additional factors that could impact outcomes and our results include those described in the Risk Factors section of our Annual Report on Form 10-K and our Quarterly Reports on Form 10-Q. filed with the Securities and Exchange Commission. Any forward-looking statements speak only as of the date of this press release and the Company assumes no obligation to update any forward-looking statement.

About MIMEDX

MIMEDX is a pioneer and leader focused on helping humans heal. With more than a decade and a half of helping clinicians manage chronic and other hard-to-heal wounds, MIMEDX provides a leading portfolio of products for applications in the wound care, burn, and surgical sectors of healthcare. The Company’s vision is to be the leading global provider of healing solutions through relentless innovation to restore quality of life. For additional information, please visit www.mimedx.com.

Contact:
Matt Notarianni
Investor Relations
470.304.7291
mnotarianni@mimedx.com


Selected Unaudited Financial Information

MiMedx Group, Inc.
Condensed Consolidated Balance Sheets
(in thousands) Unaudited
  December 31,
    2025       2024  
ASSETS      
Current assets:      
Cash and cash equivalents $ 166,121     $ 104,416  
Accounts receivable, net   75,707       55,828  
Inventory   25,340       23,807  
Other current assets   10,303       7,835  
Total current assets   277,471       191,886  
Property and equipment, net   4,713       5,944  
Deferred tax assets   19,596       28,306  
Goodwill   19,441       19,441  
Intangible assets, net   14,158       11,626  
Other assets   7,274       6,712  
Total assets $ 342,653     $ 263,915  
LIABILITIES AND STOCKHOLDERS’ EQUITY      
Current liabilities:      
Current portion of long term debt $ 1,500     $ 1,000  
Accounts payable   14,528       7,409  
Accrued compensation   31,065       23,667  
Accrued expenses   11,383       9,012  
Other current liabilities   5,790       4,507  
Total current liabilities   64,266       45,595  
Long term debt, net   16,467       17,830  
Other liabilities   5,372       7,383  
Total liabilities $ 86,105     $ 70,808  
Stockholders’ equity      
Common stock; $.001 par value; 250,000,000 shares authorized, 148,093,920 issued and outstanding at December 31, 2025 and 146,932,032 issued and outstanding at December 31, 2024   148       147  
Additional paid-in capital   299,081       284,219  
Accumulated deficit   (42,681 )     (91,259 )
Total stockholders’ equity   256,548       193,107  
Total liabilities and stockholders’ equity $ 342,653     $ 263,915  
       

MiMedx Group, Inc.
Condensed Consolidated Statements of Operations
(in thousands, except share and per share amounts) Unaudited
  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net sales $ 118,095     $ 92,907     $ 418,630     $ 348,879  
Cost of sales   19,055       16,909       73,013       60,073  
Gross profit   99,040       75,998       345,617       288,806  
               
Operating expenses:              
Selling, general and administrative   73,073       61,043       266,194       225,087  
Research and development   4,761       3,571       15,097       12,341  
Investigation, restatement and related   —       43       —       (8,698 )
Amortization of intangible assets   128       194       439       765  
Impairment of intangible assets   —       94       —       446  
Operating income   21,078       11,053       63,887       58,865  
               
Other income (expense), net              
Interest income (expense), net   904       403       2,933       (1,006 )
Other expense, net   (186 )     (208 )     (558 )     (565 )
Income from continuing operations before income tax   21,796       11,248       66,262       57,294  
Income tax provision (expense) benefit from continuing operations   (6,605 )     (3,811 )     (17,684 )     (15,296 )
Net income from continuing operations   15,191       7,437       48,578       41,998  
Income (loss) from discontinued operations, net of tax   —       —       —       421  
Net income $ 15,191     $ 7,437     $ 48,578     $ 42,419  
Net income available to common stockholders from continuing operations $ 15,191     $ 7,437     $ 48,578     $ 41,998  
               
Basic net income (loss) per common share:              
Continuing operations $ 0.10     $ 0.05     $ 0.33     $ 0.29  
Discontinued operations   —       —       —       —  
Basic net income per common share: $ 0.10     $ 0.05     $ 0.33     $ 0.29  
               
Diluted net income (loss) per common share:              
Continuing operations $ 0.10     $ 0.05     $ 0.32     $ 0.28  
Discontinued operations   —       —       —       —  
Diluted net income (loss) per common share: $ 0.10     $ 0.05     $ 0.32     $ 0.28  
               
Weighted average common shares outstanding – basic   148,091,670       147,008,235       147,793,069       146,979,354  
Weighted average common shares outstanding – diluted   150,189,160       149,242,415       149,724,507       149,049,197  
                               

MiMedx Group, Inc.
Condensed Consolidated Statements of Cash Flows
(in thousands) Unaudited
  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net cash flows provided by operating activities $ 24,956     $ 18,782     $ 74,003     $ 66,198  
Net cash flows used in investing activities   (335 )     (2,767 )     (6,886 )     (9,583 )
Net cash flows used in financing activities   (583 )     (400 )     (5,412 )     (34,199 )
Net change in cash $ 24,038     $ 15,615     $ 61,705     $ 22,416  
                               

Reconciliation of Non-GAAP Measures

In addition to our GAAP results, we provide certain non-GAAP measures including Adjusted EBITDA, related margins, Free Cash Flow, Adjusted Gross Profit, Adjusted Gross Margin and Adjusted Net Income. We believe that the presentation of these measures provides important supplemental information to management and investors regarding our performance. These measures are not a substitute for GAAP measures. Company management uses these non-GAAP measures as aids in monitoring our ongoing financial performance from quarter-to-quarter and year-to-year on a regular basis and for benchmarking against comparable companies.

These non-GAAP financial measures reflect the exclusion of the following items:

  • Share-based compensation expense – expense recognized related to awards to employees and our board of directors pursuant to our share-based compensation plans. This expense is reflected amongst cost of sales, research and development expense, and selling, general, and administrative expense in the consolidated statements of operations.
  • Investigation, restatement, and related (benefit) expense – expenses incurred toward the legal defense of the Company and advanced on behalf of certain former officers and directors, net of negotiated reductions and settlements of amounts previously advanced, related to certain legal matters. This expense is reflected in the line of the same name in our consolidated statements of operations.
  • Impairment of intangible assets – reflects the impairment of intangibles. This expense is reflected in the line of the same name in our consolidated statements of operations.
  • Transaction-related expenses – reflects expenses incrementally incurred resulting from the consummation of material strategic transactions or the integration of acquired assets or operations into our core business.
  • Strategic legal and regulatory expenses – With respect to the three months and year ended December 31, 2025, this relates to litigation and regulatory expenses. Litigation expenses incurred relate to suits filed against former employees and their employers for violation of non-compete and non-solicitation agreements and related matters. Regulatory expenses relate to legal fees incurred stemming from action taken against the United States Food & Drug Administration (“FDA”) surrounding the designation of one of our products.
  • Loss on extinguishment of debt – reflects the excess of cash paid to extinguish debt over the carrying value of the debt on our balance sheet upon the repayment and termination of a loan agreement. With respect to the year ended December 31, 2025, this relates to the repayment and termination of the Company’s loan agreement with Hayfin. Amounts in this line reflect (i) prepayment premium paid and (ii) write-offs of unamortized original issue discount and deferred financing costs.
  • Expenses related to the Disbanding of Regenerative Medicine – incremental expenses recognized or incurred directly as a result of our announcement to disband our Regenerative Medicine segment.
  • Amortization of acquired intangible assets – reflects amortization expense recognized solely related to assets which were acquired as part of a transaction. These expenses are reflected in cost of sales in our consolidated statements of operations.
  • Reorganization expenses – reflects severance expense arising from the enactment of various strategic initiatives, including separations from certain officers of the Company.
  • Income Tax Adjustment – for purposes of calculating Adjusted Net Income and Adjusted Earnings Per Share, reflects our expectation of a long-term effective tax rate, which is normalized and balance sheet-agnostic. Actual reporting tax expense will be based on GAAP earnings, and may differ from the expected long-term effective tax rate due to a variety of factors, including the tax treatment of various transactions included in GAAP net income and other reconciling items that are excluded in determining Adjusted Net Income and Adjusted EPS. The actual long-term normalized effective tax rate was 25% for each of the years ended December 31, 2025 and 2024.

Adjusted EBITDA and Adjusted EBITDA margin

Adjusted EBITDA consists of GAAP net income excluding: (i) share-based compensation, (ii) income tax provision, (iii) amortization of intangible assets, (iv) strategic legal and regulatory expenses, (v) interest (income) expense, net, (vi) depreciation expense, (vii) reorganization expenses, (viii) transaction-related expenses, (ix) investigation, restatement and related expense (benefit), (x) impairment of intangible assets, and (xi) expenses related to disbanding of the Regenerative Medicine business unit.

A reconciliation of GAAP net income to Adjusted EBITDA appears in the table below (dollars in thousands):

  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net Income $ 15,191     $ 7,437     $ 48,578     $ 42,419  
Non-GAAP Adjustments:              
Share-based compensation   2,463       4,693       16,396       16,933  
Income tax provision   6,605       3,811       17,684       15,296  
Amortization of intangible assets   2,648       2,426       12,617       3,762  
Strategic legal and regulatory expenses   2,494       1,140       9,185       2,806  
Interest (income) expense, net   (904 )     (403 )     (2,933 )     1,006  
Depreciation expense   572       564       2,264       2,279  
Reorganization expense   203       —       1,029       —  
Transaction related expenses   103       (38 )     902       612  
Investigation, restatement and related expenses   —       44       —       (8,698 )
Impairment of intangible assets   —       94       —       446  
Expenses related to disbanding of Regenerative Medicine business unit   —       —       —       (421 )
Adjusted EBITDA $ 29,375     $ 19,768     $ 105,722     $ 76,440  
Adjusted EBITDA margin   24.9 %     21.3 %     25.3 %     21.9 %


Adjusted Net Income and Adjusted Gross Margin

Adjusted Net Income provides a view of our operating performance, exclusive of certain items which are non-recurring or not reflective of our core operations.

Adjusted Net Income is defined as GAAP net income plus (i) amortization of acquired intangible assets, (ii) strategic legal and regulatory expenses, (iii) transaction-related expenses, (iv) reorganization expenses, (v) investigation, restatement and related expense (benefit), (vi) impairment of intangible assets, (vii) loss on extinguishment of debt, (viii) expenses related to disbanding of Regenerative Medicine business unit, and (ix) the long-term effective income tax rate adjustment.

Each of the adjustments to reconcile Adjusted Net Income to GAAP net income affect individual financial statement captions which are reflected in our consolidated statements of operations, including gross profit. Adjusted Gross Profit is therefore defined as GAAP gross profit plus (i) amortization of acquired intangible assets, (ii) strategic legal and regulatory expenses, (iii) transaction-related expenses, (iv) reorganization expenses, (v) investigation, restatement and related expense (benefit), (vi) impairment of intangible assets, (vii) loss on extinguishment of debt, (viii) expenses related to disbanding of Regenerative Medicine business unit, and (ix) the long-term effective income tax rate adjustment
to the extent that these adjustments impact GAAP gross profit. Adjusted Gross Margin is calculated as Adjusted Gross Profit divided by GAAP net sales.
A reconciliation of GAAP net income to Adjusted Net Income appears in the table below (in thousands):

  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net income $ 15,191     $ 7,437     $ 48,578     $ 42,419  
Amortization of acquired intangible assets   2,519       2,232       12,178       2,997  
Strategic legal and regulatory expenses   2,494       1,140       9,185       2,806  
Transaction related expenses   103       (38 )     902       612  
Reorganization expense   203       —       1,029       —  
Investigation, restatement and related expense (benefit)   —       43       —       (8,698 )
Impairment of intangible assets   —       94       —       446  
Loss on extinguishment of debt   —       —       —       1,401  
Expenses related to disbanding of Regenerative Medicine business unit   —       —       —       (421 )
Long-term effective income tax rate adjustment   (174 )     130       (4,705 )     1,082  
Adjusted net income $ 20,336     $ 11,038     $ 67,167     $ 42,644  

A reconciliation of various line items included in our GAAP unaudited condensed consolidated statements of operations to Adjusted Net Income, including Adjusted Gross Profit for the three months and years ended December 31, 2025 and 2024 are presented in the tables below (in thousands):

  Three months ended December 31, 2025
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 99,040     $ 73,073     $ 4,761   $ 15,191  
Amortization of acquired intangible assets   2,519       —       —     2,519  
Strategic legal and regulatory expenses   —       (2,494 )     —     2,494  
Reorganization expense       (203 )         203  
Transaction-related expenses   —       (90 )     —     103  
Long-term effective income tax rate adjustment   —       —       —     (174 )
Non-GAAP Measure $ 101,559     $ 70,286     $ 4,761   $ 20,336  
               
Reported Gross Profit Margin   83.9 %            
Adjusted Gross Profit Margin   86.0 %            

  Three months ended December 31, 2024
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 75,998     $ 61,043     $ 3,571   $ 7,437  
Investigation, restatement and related expenses   —       —       —     43  
Impairment of intangible assets   —       —       —     94  
Amortization of acquired intangible assets   2,232       —       —     2,232  
Transaction-related expenses   —       (30 )     —     (38 )
Strategic legal and regulatory expenses   —       (1,140 )     —     1,140  
Long-term effective income tax rate adjustment   —       —       —     130  
Non-GAAP Measure $ 78,230     $ 59,873     $ 3,571   $ 11,038  
               
Reported Gross Profit Margin   81.8 %            
Adjusted Gross Profit Margin   84.2 %            

  Year Ended December 31, 2025
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 345,617     $ 266,194     $ 15,097   $ 48,578  
Amortization of acquired intangible assets   12,178       —       —     12,178  
Strategic legal and regulatory expenses   —       (9,185 )     —     9,185  
Transaction-related expenses   —       (779 )     —     902  
Reorganization expense   —       (1,029 )     —     1,029  
Long-term effective income tax rate adjustment   —       —       —     (4,705 )
Non-GAAP Measure $ 357,795     $ 255,201     $ 15,097   $ 67,167  
               
Reported Gross Profit Margin   82.6 %            
Adjusted Gross Profit Margin   85.5 %            

  Year Ended December 31, 2024
  Gross Profit   Selling, General & Administrative Expense   Research and Development Expense   Net Income
Reported GAAP Measure $ 288,806     $ 225,087     $ 12,341     42,419  
Loss on extinguishment of debt   —       —       —     1,401  
Investigation, restatement and related expenses   —       —       —     (8,698 )
Impairment of intangible assets   —       —       —     446  
Amortization of acquired intangible assets   2,997       —       —     2,997  
Transaction-related expenses   —       (551 )     —     612  
Strategic legal and regulatory expenses   —       (2,806 )     —     2,806  
Expenses related to disbanding of Regenerative Medicine Business Unit   —       —       —     (421 )
Long-term effective income tax rate adjustment   —       —       —     1,082  
Non-GAAP Measure $ 291,803     $ 221,730     $ 12,341   $ 42,644  
               
Reported Gross Profit Margin   82.8 %            
Adjusted Gross Profit Margin   83.6 %            


Adjusted Earnings Per Share

Adjusted Earnings Per Share is intended to provide a normalized view of earnings per share by removing items that may be irregular, one-time, or non-recurring from net income. This enables us to identify underlying trends in our business that could otherwise be masked by such items. Adjusted Earnings Per Share consists of GAAP diluted net income per common share including adjustments for: (i) amortization of acquired intangible assets, (ii) strategic legal and regulatory expenses, (iii) transaction-related expenses, (iv) reorganization expenses, (v) investigation, restatement and related expense (benefit), (vi) impairment of intangible assets, (vii) loss on extinguishment of debt, (viii) expenses related to disbanding of Regenerative Medicine business unit, and (ix) the long-term effective income tax rate adjustment. The effect of antidilution reflects the changes resulting from the removal of the dilutive impact of convertible securities which were dilutive for purposes of calculating GAAP net income per common share, but are antidilutive for non-GAAP purposes.

A reconciliation of GAAP diluted earnings per share to Adjusted Earnings Per Share appears in the table below (per diluted share):

  Three Months Ended December 31,   Year Ended December 31,
    2025     2024     2025       2024  
GAAP net income (loss) per common share – diluted $ 0.10   $ 0.05   $ 0.32     $ 0.28  
Loss on extinguishment of debt   0.00     0.00     0.00       0.01  
Investigation, restatement and related (benefit) expense   0.00     0.00     0.00       (0.06 )
Impairment of intangible assets   0.00     0.00     0.00       0.00  
Amortization of acquired intangible assets   0.02     0.01     0.08       0.02  
Transaction related expenses   0.00     0.00     0.01       0.00  
Strategic legal and regulatory expenses   0.02     0.01     0.06       0.02  
Expenses related to disbanding of Regenerative Medicine business unit   0.00     0.00     0.00       0.00  
Reorganization expenses   0.00     0.00     0.01       0.00  
Long-term effective income tax rate adjustment   0.00     0.00     (0.03 )     0.01  
Adjusted Earnings Per Share $ 0.14   $ 0.07   $ 0.45     $ 0.28  
               
Weighted average common shares outstanding – adjusted   150,189,160     149,242,415     149,724,507       149,049,197  


Free Cash Flow

Free Cash Flow is intended to provide a measure of our ability to generate cash in excess of capital investments. It provides management with a view of cash flows which can be used to finance operational and strategic investments.

Free Cash Flow is defined as net cash provided by operating activities less capital expenditures, including purchases of equipment.

A reconciliation of GAAP net cash flows provided by operating activities to Free Cash Flow appears in the table below (in thousands):

  Three Months Ended December 31,   Year Ended December 31,
    2025       2024       2025       2024  
Net cash flows provided by operating activities $ 24,956     $ 18,782       74,003       66,198  
Capital expenditures, including purchases of equipment   (285 )     (263 )     (1,033 )     (1,683 )
Free Cash Flow $ 24,671     $ 18,519     $ 72,970     $ 64,515  


Other Information

Net Sales by Product Category by Quarter

Below is a summary of net sales by product category (in thousands):

    2025     2024
  Q1   Q2   Q3   Q4   Q1   Q2   Q3   Q4
Wound $ 56,073   $ 64,476   $ 77,098   $ 78,679   $ 57,049   $ 57,547   $ 55,052   $ 61,357
Surgical   32,132     34,129     36,627     39,416     27,660     29,660     29,005     31,550
Net sales $ 88,205   $ 98,605   $ 113,725   $ 118,095   $ 84,709   $ 87,207   $ 84,057   $ 92,907


Selling, General and Administrative

Below is the breakout of selling, general and administrative expense by selling and marketing and general and administrative (in thousands):

    2025     2024
  Q1   Q2   Q3   Q4   Q1   Q2   Q3   Q4
Selling and marketing $ 46,861   $ 47,867   $ 53,720   $ 61,233   $ 44,477   $ 41,725   $ 41,721   $ 47,638
General and administrative   13,108     16,284     15,281     11,840     10,652     13,676     11,795     13,403
Selling, general and administrative $ 59,969   $ 64,151   $ 69,001   $ 73,073   $ 55,129   $ 55,401   $ 53,516   $ 61,041