PRESS RELEASE

Heidelberg Pharma’s Lead ATAC Candidate HDP-101 Shows Progress in Phase I/IIa Trial in Multiple Myeloma

• Evidence of clinical activity observed in Cohort 8, including stringent complete remission in two patients from Cohort 8
• HDP-101 continues to demonstrate a favorable safety profile with no dose-limiting toxicities observed in Cohort 8

• R&D Webinar to be hosted on 11 November 2025 at 05:00 pm CET (08:00 am PST)

Ladenburg, Germany, 6 November 2025 – Heidelberg Pharma AG (FSE: HPHA), a clinical-stage biotech company developing innovative Antibody Drug Conjugates (ADCs), today announced that HDP-101 (INN: pamlectabart tismanitin), the Company’s lead ATAC candidate for the treatment of relapsed or refractory multiple myeloma, shows further clinical activity in Cohort 8 at a dose level of 140 µg/kg. These findings are highlighted by observed stringent complete remissions in two patients from Cohort 8.

Seven patients were evaluated in Cohort 8, and all patients demonstrated a favorable safety and tolerability profile throughout. Encouraging signs of clinical activity have also emerged. Four patients showed biological activity of HDP-101 (INN: pamlectabart tismanitin), with one partial response, one very good partial response and two stringent complete remissions (sCR). For sCR, no tumor cells are detectable in blood and bone marrow.

Dr András Strassz, Chief Medical Officer at Heidelberg Pharma, said: “We are very delighted by the data seen so far. Several patients across different cohorts have shown objective responses and promising anti-tumor activity. Observing two stringent complete remissions is an encouraging validation of our therapeutic approach. We have previously seen complete remission in one patient from Cohort 5, but in Cohort 8 onset of the response was more rapid. These findings further strengthen our confidence in the therapeutic potential of HDP-101 in heavily pretreated patients with relapsed or refractory multiple myeloma, and we are now progressing with Cohort 9 with an escalated dose of 175 µg/kg to continue its clinical evaluation.”

Heidelberg Pharma’s Phase I/IIa clinical study is a non-randomized, open-label, dose escalation trial actively enrolling patients with relapsed or refractory multiple myeloma or other BCMA-expressing plasma cell disorders. The study is designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of HDP-101 (INN: pamlectabart tismanitin) in this patient population.

Heidelberg Pharma will discuss these findings in an R&D webinar on 11 November 2025 at 05:00 pm CET (11:00 am ET; 08:00 am PST), for investors, analysts, and media.

The webinar will feature presentations by the Heidelberg Pharma management team and Key Opinion Leader (KOL) Professor Marc-Steffen Raab, Head of the Myeloma Center at the University Hospital Heidelberg and clinical investigator of the study.

For further information on the R&D webinar, or to register your attendance, please use the link below:

https://us06web.zoom.us/webinar/register/WN_AG_mESPaT-aSsm8_O2DllA

A recording of the R&D webinar will be accessible via the press & investor section of the Company website after the event.

About Heidelberg Pharma

Heidelberg Pharma is a biopharmaceutical company working on a new treatment approach in oncology and developing novel drugs based on its ADC technologies for the targeted and highly effective treatment of cancer. ADCs are antibody-drug conjugates that combine the specificity of antibodies with the efficacy of toxins to fight cancer. Selected antibodies are loaded with cytotoxic compounds, the so-called payloads, that are transported into diseased cells. Inside the cells, the toxins then unleash their effect and kill the diseased cells.

Heidelberg Pharma is the first company to use the compound Amanitin from the green death cap mushroom in cancer therapy. The biological mechanism of action of the toxin represents a new therapeutic modality and is used as a compound in the Amanitin-based ADC technology, the so-called ATAC technology.

The lead candidate HDP-101 (INN: pamlectabart tismanitin) is a BCMA ATAC in clinical development for multiple myeloma. The candidate has been granted Orphan Drug Designation and Fast Track Designation from the FDA. A second ATAC candidate, HDP-102 is in clinical development stage in Non-Hodgkin Lymphoma. HDP-103 against metastatic castration-resistant prostate cancer and HDP-104 targeting gastrointestinal tumors such as colorectal cancer have completed preclinical development. Heidelberg Pharma is open for partnering.

The company is based in Ladenburg, Germany, and is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol HPHA. More information is available at www.heidelberg-pharma.com

ATAC^® is a registered trademark of Heidelberg Pharma Research GmbH.

Contact Heidelberg Pharma AG Sylvia Wimmer Director Corporate Communications Tel.: +49 89 41 31 38-29 E-Mail: investors@hdpharma.com Gregor-Mendel-Str. 22, 68526 Ladenburg	IR/PR-Support MC Services AG Katja Arnold (CIRO) Managing Director & Partner Tel.: +49 89 210 228-40 E-Mail: katja.arnold@mc-services.eu
International IR/PR-Support Optimum Strategic Communications Mary Clark, Zoe Bolt, Aoife Minihan Tel: +44 20 3882 9621 Email: HeidelbergPharma@optimumcomms.com

This communication contains certain forward-looking statements relating to the Company’s business, which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “will” “should” “future”, “potential” or similar expressions or by a general discussion of the Company’s strategy, plans or intentions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results of operations, financial condition, performance, or achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors and partners are cautioned not to place undue reliance on such forward-looking statements. We disclaim any obligation to update any such forward-looking statements to reflect future events or developments.

Ad hoc announcement pursuant to Art. 53 LR

SKAN will miss sales and profit expectations for 2025 – order intake and backlog are developing very positively and laying a strong foundation for 2026

Allschwil, November 6, 2025 – The SKAN Group conducted a planned review of its project portfolio in the last days. This assessment identified delays in several projects that will affect sales and earnings in the current financial year. The SKAN Group will therefore not meet its sales and profit expectations for 2025. Order intake continues to develop very positively and lays the foundation for a strong 2026 financial year, which will be significantly above 2024 and 2025. The medium-term targets are confirmed.

The SKAN Group now expects net sales for the 2025 financial year to decline by a high single-digit percentage compared to the previous year. The EBITDA margin for 2025 is expected to be in the low double-digit range. This is significantly below the guidance for 2025, which had targeted net sales growth in the mid-single-digit range and an EBITDA margin between 14% and 16%.

The reason for this is that additional projects have been postponed since the summer, pushing significant portions of the highest turnover month of December into 2026. As a result of the lost sales, this year’s EBITDA is correspondingly lower.

The SKAN Group’s order intake continues to develop very positively in the current financial year, with particular demand for filling lines for oncology applications and biotechnologically produced injectable large molecules. It is already foreseeable that the order backlog will very likely reach a new high by the end of the year. This provides a strong basis for a successful 2026 financial year.

The medium- and long-term growth prospects for the SKAN Group remain positive, supported by structural market growth, a strong global competitive position, and a solid project pipeline. SKAN is therefore confirming its medium-term targets: It expects net sales to grow at an annual rate in the mid- to upper teens. The EBITDA margin is to be gradually increased to the upper teens in the mid-term, with potential for further increase beyond the mid-term period.

 

Contacts:

Thomas Balmer, ir@skan.com, +41 79 703 87 28
Alexandre Müller, ir@skan.com, +41 79 635 64 13

Financial calendar:

24 March 2026	Publication Annual Results 2025
7 May 2026	Annual General Meeting 2026

 

SKAN – together always one step ahead

SKAN is a pioneer in the field of aseptic and aseptic-toxic manufacturing processes for the (bio)pharmaceutical industry. The company is the market and technology leader for high-quality, process-critical isolator systems for filling drugs according to strict sterility standards. In addition, the company offers its customers process support, services and consumables. Innovative solutions and an efficient life-cycle support organisation make SKAN an important partner for the pharmaceutical and biotech industry, CMOs (Contract Manufacturing Organisations) and research laboratories worldwide. Founded in 1968, SKAN today employs close to 1700 people. More than half of them work at the Allschwil headquarters in the Life Sciences Hub of the Basel region. The other employees are located among the subsidiaries in Switzerland, Germany, Belgium, France, Slovenia, Croatia, Japan, the USA and Brazil.

 

Frauenfeld, 6 November 2025

Press release

DocMorris announces the start of the tender offer period for its Outstanding Convertible Bonds due 2026

After publication of the Offer Notice on 22 October 2025 and the end of the cooling-off period, DocMorris announces the start of the tender offer period for its Outstanding Convertible Bonds due 2026. The Tender Offer price for each of the Outstanding Convertible Bonds due 2026 amounts to CHF 1,035 per bond, corresponding to 103.50% of the par value, plus accrued and unpaid interest.

The tender offer period starts today and is expected to expire on 12 November 2025 at 4:00pm CET. Settlement of the Tender Offer is expected to occur on 17 November 2025. The bonds are listed and traded on SIX Swiss Exchange (ISIN: CH1210198169; SSN: A3K86S).

This press release is not an offer for the repurchase of the Outstanding Convertible Bonds due 2026 but only discloses the most important terms of the planned Tender Offer. The Tender Offer is solely made based on the Tender Offer notice published on 22 October 2025 in accordance with Swiss Tender Offer rules.

 

Investors and analyst contact
Dr. Daniel Grigat, Head of Investor Relations & Sustainability
Email: ir@docmorris.com, phone: +41 52 560 58 10

Media contact
Torben Bonnke, Director Communications
Email: media@docmorris.com, phone: +49 171 864 888 1

Agenda

20 January 2026	Full-year 2025 revenue
19 March 2026	Full-year 2025 results and outlook 2026 (conference call/webcast)
16 April 2026	Q1/2026 Trading update
12 May 2026	Annual General Meeting, Zurich

 

DocMorris
The Swiss-based DocMorris AG is a leading company in the fields of online pharmacy, telemedicine and marketplace with strong brands in Germany and other European countries. Deliveries are mainly from the highly automated logistics centre in Heerlen, the Netherlands. TeleClinic is Germany’s largest telemedicine platform, connecting patients with more than 5,000 physicians. DocMorris operates leading marketplaces for health and personal care products in Southern Europe. With its broad range of products and services, DocMorris is pursuing its vision of becoming the leading digital health companion for everyone to manage their health in one click. Around 1,600 employees in Germany, the Netherlands, Spain, France, Portugal and Switzerland generated an external revenue of CHF 1,085 million serving more than10 million active customers in 2024. The shares of DocMorris AG are listed on the SIX Swiss Exchange (securities number 4261528, ISIN CH0042615283, ticker DOCM). For further information, please visit corporate.docmorris.com.

 

Disclaimer

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The Supervisory Board of SCHOTT Pharma Management AG has today appointed Christian Mias as the new Chief Executive Officer (CEO) of SCHOTT Pharma, effective May 1, 2026. He will succeed Andreas Reisse, who will retire as planned at the end of April 2026. Christian Mias has held various management positions within the SCHOTT Group since 2007, most recently serving as Head of the Business Unit Electronic Packaging.
 

SCHOTT Pharma: Christian Mias to succeed Andreas Reisse as CEO of SCHOTT Pharma

• Andreas Reisse to retire as CEO of SCHOTT Pharma as planned
• Christian Mias, Executive Vice President of SCHOTT’s Electronic Packaging Business Unit, appointed as new CEO of SCHOTT Pharma effective May 1^st, 2026
• Seamless leadership transition ensured

The Supervisory Board of SCHOTT Pharma Management AG has appointed Christian Mias as CEO of SCHOTT Pharma. He will take over from Andreas Reisse, who will retire as planned in April 2026. Reisse will actively support a seamless leadership transition over the coming months to ensure continuity and stability for the company and the entire team.

Christian Mias, born in Iserlohn in 1974, will succeed Andreas Reisse starting May 1^st. As an industrial engineer with a doctoral degree, he looks back on more than 20 years of management experience, including over 18 years within the SCHOTT group. Before joining SCHOTT, he started his career as Commercial Project Manager at Siemens AG. Christian Mias gained significant experience in the pharmaceutical industry when joining SCHOTT Tubing, which produces intermediate products for the pharma sector, including SCHOTT Pharma. Throughout his career at SCHOTT, Christian has held leadership positions across various business units and continents, including roles as Managing Director in Brazil and Chief Operating Officer in the United States. In such roles, he successfully drove profitable growth by optimizing processes, improving productivity, and increasing earnings quality. Since 2016, he has served as Vice President, and since 2018 as Executive Vice President, currently heading the Business Unit Electronic Packing. Across his executive positions, Christian combined strategic foresight with operational discipline to drive the organizations toward consistent growth and strong financial performance.

Peter Goldschmidt, Chairman of the Supervisory Board of SCHOTT Pharma AG & Co. KGaA, said: “We are delighted to welcome Christian Mias as the new CEO of SCHOTT Pharma. His proven success within the SCHOTT Group, combined with strategic expertise and strong execution -demonstrated through integrative, performance-oriented, and participative leadership – makes him an excellent fit to lead SCHOTT Pharma into its next phase of profitable growth.

We are confident that Christian, together with Reinhard Mayer (CFO), will continue to drive profitable growth and further strengthen SCHOTT Pharma’s position as a global leader in pharmaceutical packaging and delivery systems.”

 

Commenting on his appointment, Christian Mias said: “I am honored to join SCHOTT Pharma at such an exciting time in the company’s journey. SCHOTT Pharma has built an exceptional reputation for innovation, quality, and reliability in the pharmaceutical industry. I look forward to working with the excellent team at SCHOTT Pharma to build upon this strong foundation and drive continued growth while advancing our mission to improve global healthcare. I would also like to thank Andreas Reisse for his outstanding leadership and dedication over the years. His vision and commitment have been instrumental in shaping SCHOTT Pharma’s success. I am looking forward to working together with Reinhard Mayer (CFO) on shaping the future of SCHOTT Pharma.”

 

Andreas Reisse has been with the SCHOTT Group since 1987 and has led the “Pharmaceutical Systems” division since 2010, which has been listed on the Frankfurt Stock Exchange as SCHOTT Pharma AG & Co. KGaA since 2023. He is now retiring upon reaching the statutory age limit for members of the Executive Board.

“Andreas Reisse has played an indispensable role in developing SCHOTT Pharma into one of the world’s leading companies in pharmaceutical containment solutions and delivery systems. Under his leadership, the company has achieved remarkable growth, delivered industry-leading innovations, and successfully transitioned to a publicly listed company. We thank him for his exceptional contributions and wish him all the best for his well-deserved retirement,” said Peter Goldschmidt.

Andreas Reisse commented: “It has been a privilege to spend so many years at SCHOTT Pharma and within the SCHOTT Group. I am very grateful for the collaboration and trust I have had with all stakeholders and the Supervisory Board. Together with a dedicated management team, we have established SCHOTT Pharma as a key partner in the pharmaceutical industry and achieved significant milestones, such as the successful IPO. As I prepare for retirement, I am confident that the company is well positioned for continued success and innovation. SCHOTT Pharma will be in excellent hands with Christian Mias, whom I have known and appreciated for almost two decades.”

For further news about SCHOTT Pharma, please visit our Media Center.

 

About SCHOTT Pharma

Human health matters. That is why SCHOTT Pharma designs solutions grounded in science to ensure that medications are safe and easy to use for people around the world. Every minute, more than 25,000 people receive an injection packed in a SCHOTT Pharma product. The portfolio comprises drug containment solutions and delivery systems for injectable drugs ranging from prefillable glass and polymer syringes to cartridges, vials, and ampoules. Every day, a team of around 4,700 people from over 60 nations works at SCHOTT Pharma to contribute to global healthcare. The company is represented in all main pharmaceutical hubs with 17 manufacturing sites in Europe, North and South America, and Asia. With over 1,000 patents and technologies developed in-house and a state-of-the-art R&D center in Switzerland, the company is focused on developing innovations for the future. SCHOTT Pharma AG & Co. KGaA is headquartered in Mainz, Germany and listed on the Frankfurt Stock Exchange as part of the SDAX. It is majority owned by SCHOTT AG, which is owned by the Carl Zeiss Foundation. In light of this spirit, SCHOTT Pharma is committed to sustainable development for society and the environment. Currently, SCHOTT Pharma has over 1,800 customers including the top 30 leading pharma manufacturers for injectable drugs and generated revenue of EUR 957 million in the fiscal year 2024. Further information at www.schott-pharma.com.   

Contact

Katrin Schreyer

Corporate Communications

Tel.: +49 (0) 6131 66-4932

E-Mail: katrin.schreyer@schott.com 

 

Lea Kaiser

Media Relations

Tel.: +49 (0) 6131 66-2422

E-Mail: lea.kaiser@schott.com 

 

Tobias Erfurth

Head of Investor Relations

E-Mail: Tobias.Erfurth@schott.com

 

Jasko Terzic, CFA

Senior Manager Investor Relations

E-Mail: Jasko.Terzic@schott.com

 

 

 

 

 

Group revenues of € 535.1 m ((7.1)%); Discovery & Preclinical Development segment (“D&PD”, (12.3)%) still sees soft demand; Just – Evotec Biologics (“JEB”; +11.3%) above-expectation; further accelerating growth on non-Sandoz / non-DOD business Strong scientific advancements of co-developed asset pipeline: Expecting up to four molecules in clinical phase II in next six to nine months Signing of landmark industry transaction with Sandoz on 04 November, resulting in payments potentially over US$ 650 m plus royalties on portfolio of up to 10 biosimilar molecules 2025 guidance and 2028 outlook confirmed

Hamburg, Germany, 05 November 2025:

Evotec SE (Frankfurt Stock Exchange: EVT, SDAX/TecDAX, Prime Standard, ISIN: DE0005664809, WKN 566480; NASDAQ: EVO) today announced its business update for 9M 2025, illustrating the ongoing systematic execution of its strategy. In the D&PD segment, the market for early drug discovery services remained soft, while strategic partnerships are on track and Evotec records strong progress in its partnered asset pipeline. JEB continues its strong momentum and reports further accelerating growth in the non-Sandoz / non-DoD business.

After the end of the period, Evotec signed a > US$ 650 m landmark transaction with Sandoz AG (SIX:SDZ/OTCQX:SDZNY) on 04 November. According to the terms of the agreement, Sandoz will acquire 100% of Just – Evotec Biologics EU in Toulouse plus an indefinite technology license to Evotec’s continuous manufacturing platform technology for a payment of approximately US$ 350 m in cash. The agreement includes additional license fees and development revenues including success-based milestones, adding up to more than US$ 300 m in the coming years, replacing existing contractual commitments. In the future, Evotec expects to benefit from royalties on a portfolio of up to ten biosimilars in technical and early development, targeting a net-originator sales market of more than US$ 90 bn.

Dr Christian Wojczewski, Chief Executive Officer of Evotec:

“Evotec remains firmly on track in delivering against its strategic objectives, demonstrating strong execution for future sustainable and profitable growth. Despite a continued softness in the early drug discovery market, we are seeing first signals of improvement in our base business in D&PD. With 11% revenue growth year-over-year, JEB is not only enjoying high demand but also delivering strong results above our expectations. The agreement with Sandoz enables us to sharpen our focus on JEB’s capabilities as a scalable technology provider with an asset-lighter model. The transaction is a testament for our world class continuous manufacturing technology. A core element of our new strategy is to sharpen our offering and reduce complexity while progress in our strategic partnerships continues to build momentum.“
 

Continuing challenges for D&PD; JEB building strong momentum

• Group revenues decrease by (7.1)% to € 535.1 m (9M 2024: € 575.7 m)
• Total D&PD revenues decrease by (12.3)% to € 392.1 m (9M 2024: € 447.1 m), due to soft demand in the early drug discovery service market; quotations are growing in number and value, negative change orders are declining
• JEB revenues increase by 11.3% to € 143.4 m (9M 2024: € 129.3 m), driven by continued strong non-Sandoz / non-Department of Defense (“DoD”) business growth of 105% year over year
• Adjusted Group EBITDA totaled € (16.9) m (9M 2024: € (6.0) m) driven by continued underutilization and a high fixed cost base in the D&PD segment as well as costs related to the ramp-up of the JEB Toulouse facility
• Cost out initiatives ahead of plan, expected to result in a total cost reduction of more than € 60 m in 2025 (2x initial target)
   

Driving growth through strategic priorities

• Significant progress in the strategic protein degradation collaboration with Bristol Myers Squibb (“BMS”) resulted in performance- and program-based payments amounting to US$ 75 m the first half of the year
• In the second quarter, Evotec reported key advancements in its neuroscience collaboration with BMS, resulting in a US$ 20 m research payment to the company
• Two partnered assets entered Phase II clinical trials
   

Events after Period-End

• In a landmark industry transaction, Evotec signs agreement with Sandoz, resulting in payments of potentially over US$ 650 m plus royalties on a portfolio of up to 10 biosimilar molecules
• Progress in the strategic preclinical neuroscience partnership with BMS resulted in a payment of US$25m to support the continued progression of joint programs
• Investigational New Drug (“IND”) submission by partner Dewpoint Therapeutics for novel oncology therapy marks culmination of the partnership, advancing a de novo development candidate from discovery through IND-enabling studies
• Evotec’s collaboration with Esperion leads to the nomination of a preclinical development candidate for the treatment of Primary Sclerosing Cholangitis, a chronic, progressive disease-causing inflammation and sclerosis of the bile ducts leading over time to liver cell damage and can result in fibrosis, cirrhosis, and eventually liver failure
   

Guidance for full-year 2025 confirmed

• Group revenues expected in the range of € 760 – 800 m (2024: € 797.0 m)
• R&D expenditures are expected in a range of € 40 – 50 m (2024: € 50.9 m)
• Adjusted Group EBITDA is expected to reach € 30 – 50 m (2024: € 22.6 m)
   

Outlook 2028

• Group revenues CAGR _2024-2028 targeted to be in a range of 8 – 12%
• Adjusted EBITDA margin 2028 expected to be above 20%

More detailed information and financial tables are available in the interim statement for the first nine months 2025 published on the Evotec website under the following link: https://www.evotec.com/en/investor-relations/financial-publications

 

Webcast/Conference Call

The Company is going to hold a conference call to discuss the results as well as provide an update on its performance. The conference call will be held in English.

Webcast details

Date:  Wednesday, 05 November 2025

Time:  2.00 pm CET (01.00 pm GMT, 08.00 am EST)

To join the audio webcast and to access the presentation slides, please register via this link.

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About Evotec SE
Evotec is a life science company that is pioneering the future of drug discovery and development. By integrating breakthrough science with AI-driven innovation and advanced technologies, we accelerate the journey from concept to cure — faster, smarter, and with greater precision.

Our expertise spans small molecules, biologics, cell therapies and associated modalities, supported by proprietary platforms such as Molecular Patient Databases, PanOmics and iPSC-based disease modeling.

With flexible partnering models tailored to our customers’ needs, we work with all Top 20 Pharma companies, over 800 biotechs, academic institutions, and healthcare stakeholders. Our offerings range from standalone services to fully integrated R&D programs and long-term strategic partnerships, combining scientific excellence with operational agility.

Through Just – Evotec Biologics, we redefine biologics development and manufacturing to improve accessibility and affordability.

With a strong portfolio of over 100 proprietary R&D assets, most of them being co-owned, we focus on key therapeutic areas including oncology, cardiovascular and metabolic diseases, neurology, and immunology.

Evotec’s global team of more than 4,800 experts operates from sites in Europe and the U.S., offering complementary technologies and services as synergistic centers of excellence. Learn more at www.evotec.com and follow us on LinkedIn and X/Twitter @Evotec.

Forward-looking statements
This announcement contains forward-looking statements concerning future events, including the proposed offering and listing of Evotec’s securities. Words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “potential,” “should,” “target,” “would” and variations of such words and similar expressions are intended to identify forward-looking statements. Such statements include comments regarding Evotec’s expectations for revenues, Group EBITDA and unpartnered R&D expenses. These forward-looking statements are based on the information available to, and the expectations and assumptions deemed reasonable by Evotec at the time these statements were made. No assurance can be given that such expectations will prove to have been correct. These statements involve known and unknown risks and are based upon a number of assumptions and estimates, which are inherently subject to significant uncertainties and contingencies, many of which are beyond the control of Evotec. Evotec expressly disclaims any obligations or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Evotec’s expectations with respect thereto or any change in events, conditions or circumstances on which any statement is based.

 

For further information, please contact:

Investor Relations

Volker Braun
EVP Head of Global Investor Relations & ESG
Volker.Braun@evotec.com

 

 

In a landmark industry transaction, Evotec signs agreement with Sandoz, resulting in payments potentially over US$ 650 m plus royalties on portfolio of up to 10 biosimilar molecules

Transaction showcases Evotec’s unique capability enabling customers to produce biologics faster and at lower costs through its continuous manufacturing technology Accelerated implementation of strategy through better monetization of technology and transitioning to an asset-lighter business model Agreement includes approximately US$ 350 m in cash for Just – Evotec Biologics manufacturing site in Toulouse and upfront technology license fees to Evotec’s continuous manufacturing platform In addition, Evotec eligible for license fees, and development revenues including success-based milestones adding up to more than US$ 300 m over the coming years, replacing existing contractual commitments Transaction covering royalties on a portfolio of up to ten biosimilars in technical and early development targeting more than US$ 90 bn of originator net sales Sale immediately earnings accretive, improving Evotec’s short, mid and long-term revenue mix, profit margins, and capital efficiency

Hamburg, Germany, 04 November 2025:
 

Evotec SE (Frankfurt Stock Exchange: EVT, SDAX/TecDAX, Prime Standard, ISIN: DE0005664809, WKN 566480; NASDAQ: EVO), a life science company that is pioneering the future of drug discovery and development, today announced the successful signing of the sale of the Just – Evotec Biologics Toulouse site to Sandoz AG (SIX: SDZ / OTCQX: SDZNY), a global leader in generic and biosimilar medicines.

Under the landmark transaction, Sandoz will acquire 100% of Just – Evotec Biologics EU plus an indefinite technology license to Evotec’s continuous manufacturing platform technology for a payment of approximately US$ 350 m in cash. The agreement includes additional license fees and development revenues including success-based milestones, adding up to more than US$ 300 m in the coming years. In the future, Evotec expects to benefit from royalties on a portfolio of up to ten biosimilars in technical and early development targeting a net originator sales market of more than US$ 90 bn.

With this acquisition, Sandoz will gain access to Evotec’s proprietary platform for integrated development and advanced continuous manufacturing of biologics via an indefinite license.

The contract signature follows the announcement in July of a non-binding term-sheet agreement on 30 July 2025. Both parties aim to close the transaction in Q4 2025 subject to meeting closing conditions including foreign direct investment (FDI) clearance by the French authorities. The transaction will have a significant positive impact on Evotec’s revenue mix, profit margins, and capital efficiency immediately after closing.

 

Dr Christian Wojczewski, Chief Executive Officer of Evotec, said:

“This is a transformative milestone for Evotec as we further leverage Just – Evotec Biologics’ capabilities and position the company as a scalable technology provider. With our unique offering, we are expanding the scope of addressable partners and shaping a new segment in the biologics manufacturing market in a very capital efficient way. Additionally, with this transaction, Evotec is delivering on its asset lighter strategy, sharpening its focus on its core strengths, and is well on track for sustainable and profitable growth.”

 

Dr Linda Zuckerman, EVP and Global Head of Just – Evotec Biologics, said:

“Sandoz’s acquisition of Just – Evotec Biologics’ Toulouse site is a powerful endorsement of our pioneering J.POD platform and its potential to revolutionize biologics manufacturing. This strategic transaction empowers Sandoz to leverage our advanced perfusion-based continuous manufacturing technology, progressing our shared mission to expand global access to affordable, high-quality biosimilars. We are proud to see our innovation continue to have a transformative impact for patients around the world.”

 

After closing of the transaction, Evotec will continue to serve our customers in the U.S. and Europe with capacity for molecular design, upstream, downstream, analytical and formulation development as well as First-In-Human to commercial biologics GMP manufacturing.

 

Evotec confirms guidance for full-year 2025 and its Outlook 2028

For the current fiscal year, the Company expects revenues in the range of € 760 – 800 m (2024: € 797.0 m);

R&D expenditures are expected in a range of € 40 – 50 m (2024: € 50.8 m);

Adjusted EBITDA¹ is expected to reach € 30 – 50 m (2024: € 22.6 m).

Outlook 2028 remains unchanged with a targeted Group revenue CAGR_2024-2028 in a range of 8 – 12% and an expected adj. EBITDA margin above 20% by 2028.

^{1 Excluding potential costs related to the transformation program in 2025
CAGR: Compound annual growth rate}

 

About Evotec SE
Evotec is a life science company that is pioneering the future of drug discovery and development. By integrating breakthrough science with AI-driven innovation and advanced technologies, we accelerate the journey from concept to cure — faster, smarter, and with greater precision.

Our expertise spans small molecules, biologics, cell therapies and associated modalities, supported by proprietary platforms such as Molecular Patient Databases, PanOmics and iPSC-based disease modeling.

With flexible partnering models tailored to our customers’ needs, we work with all Top 20 Pharma companies, over 800 biotechs, academic institutions, and healthcare stakeholders. Our offerings range from standalone services to fully integrated R&D programs and long-term strategic partnerships, combining scientific excellence with operational agility.

Through Just – Evotec Biologics, we redefine biologics development and manufacturing to improve accessibility and affordability.

With a strong portfolio of over 100 proprietary R&D assets, most of them being co-owned, we focus on key therapeutic areas including oncology, cardiovascular and metabolic diseases, neurology, and immunology.

Evotec’s global team of more than 4,800 experts operates from sites in Europe and the U.S., offering complementary technologies and services as synergistic centers of excellence. For additional information please go to www.evotec.com and follow us on X/Twitter @Evotec and LinkedIn.

Forward-looking statements
This announcement contains forward-looking statements concerning future events, including the proposed offering and listing of Evotec’s securities. Words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “potential,” “should,” “target,” “would” and variations of such words and similar expressions are intended to identify forward-looking statements. Such statements include comments regarding Evotec’s expectations for revenues, Group EBITDA and unpartnered R&D expenses. These forward-looking statements are based on the information available to, and the expectations and assumptions deemed reasonable by Evotec at the time these statements were made. No assurance can be given that such expectations will prove to have been correct. These statements involve known and unknown risks and are based upon a number of assumptions and estimates, which are inherently subject to significant uncertainties and contingencies, many of which are beyond the control of Evotec. Evotec expressly disclaims any obligations or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Evotec’s expectations with respect thereto or any change in events, conditions or circumstances on which any statement is based.

 

For further information, please contact:

Investor Relations

Volker Braun
EVP Head of Global Investor Relations & ESG
volker.braun@evotec.com