• Group operating result amounts to EUR 48.9 million (9M 2024: EUR 34.5 million)
• Consolidated group sales amounts to EUR 586.9 million (9M 2024: EUR 558.2 million)
• Overall capacity utilisation stable at 86.8%

For further information:

MEDICLIN Aktiengesellschaft
Okenstraße 27
77652 Offenburg

Investor Relations
Ender Gülcan
Tel.: +49781/488-326
ender.guelcan@mediclin.de

www.mediclin.de

About MEDICLIN Aktiengesellschaft (Ticker: MED; WKN: 659 510)

MEDICLIN ─ a company of the Asklepios Group

Mallia Aesthetics Launches 8T3 Essentials Hair Serum and
8T3 Essentials Lash & Brow Serum

• Mallia launches new web shop with its 8T3 Essentials Line
• 8T3 serums are the first products for stimulating hair growth based on the immunomodulatory mode of action of sCD83
• 8T3 Essentials Hair Serum and 8T3 Essentials Lash & Brow Serum can now be ordered via Mallia’s online shop 8T3.com

Erlangen, Germany, November 04, 2025 – Mallia Aesthetics GmbH, a company focusing on the development and commercialization of cosmetic products to stimulate hair growth, today announced the official market launch of its innovative 8T3 Essentials Hair Serum and 8T3 Essentials Lash & Brow Serum. 8T3 Essentials Serums will be available exclusively via Mallia’s online shop 8T3.com for customers in the EU.

All products in the 8T3 line are hormone-free, dermatologically tested, certified microbiome-friendly, and with excellent tolerability on sensitive skin.

8T3 Essentials Hair Serum supports and enhances hair density and thickness. The product is designed for biweekly application to the scalp using single-dose, preservative-free vials. It will be available in 6-month boxes.

8T3 Essentials Lash & Brow Serum promotes growth and thickness of eyelashes and eyebrows. The serum is sold in vials with an integrated applicator brush and should be used daily for the best results.

The 8T3 Essentials product line is built on the active ingredient MAL-838, a proprietary derivative of the human soluble CD83 protein. Mallia co-founder Prof. Dr. Alexander Steinkasserer and his team have shown that sCD83 possesses immunomodulatory properties, which can stimulate wound healing and new hair growth, and have published these results in a peer-reviewed journal.¹

Dr. Anne Asmuß, Managing Director of Mallia Aesthetics, said: “We are excited to see years of dedicated research and meticulous planning come to fruition as we today introduce our science-driven cosmetics to the market. For the first time, consumers will be able to benefit directly from the mode of action of an sCD83 derivative in the form of hormone-free, scientifically grounded formulations. With 8T3, we offer products that are convenient, safe, and designed for visible results.”

About sCD83

Soluble CD83 (sCD83) is an immunomodulatory protein that is currently being developed for the topical treatment of hair loss (MAL‑856) and stimulation of hair growth (MAL‑838). The soluble CD83 protein was first identified in 2001 by Mallia co-founder Prof. Steinkasserer. It has anti-inflammatory properties via the induction of resolution of inflammation, which promotes wound healing and induces new hair growth.¹ In addition, sCD83 has been shown to activate regulatory T cells (Tregs)², which interact directly with hair follicles and can activate them.³ Furthermore, sCD83 inhibits cell death of hair follicles and directly activates follicular stem cells, as well as keratin production, thereby stimulating new hair growth. This multimodal mode of action distinguishes sCD83 from other topically applied hair growth agents.

Topically applied, sCD83 can directly reach the hair follicles but does not penetrate through the skin and thus does not enter the bloodstream. The effect is localized, which is a major advantage over systemic treatment options, which can cause severe side effects.

About hair loss

Hormone-related hair loss in men and women (androgenetic alopecia, or AGA) is the most common form of hair loss. Worldwide, more than 70% of men and 50% of women post menopause are affected by androgenetic alopecia. Another 147 million people suffer from immune-related, circular hair loss (alopecia areata, or AA^4,5).

Androgenetic alopecia usually progresses gradually and is due to genetic and hormonal factors. In men, it often leads to a receding hairline and baldness on the top of the head, while in women it causes thinning hair in the parting area. Alopecia areata causes circular hair loss on the scalp, face or other parts of the body. It occurs when the immune system erroneously attacks hair follicles, leading to immune-mediated hair loss.

About Mallia

Mallia Innovations GmbH, based in Erlangen, Germany, is the holding company strategically driving the proprietary development and commercialization of biopharmaceutical therapies and cosmetic applications of the immunomodulatory sCD83 protein, targeting hair growth, hair loss and other dermatological indications, including wound healing.

Mallia Therapeutics GmbH focuses on the clinical development of novel therapies for patients suffering from androgenetic alopecia or alopecia areata, among other conditions. MAL-856 is based on the scientifically proven immunomodulatory mode of action of sCD83, which has been investigated for close to 25 years by Mallia Co‑founder Prof. Dr Alexander Steinkasserer.⁶

Mallia Aesthetics GmbH focuses on cosmetic applications for the stimulation of hair growth, which are also based on the scientifically validated sCD83 protein. The Company develops Innovative cosmetic products using MAL-838 that are marketed to specialists and consumers.

To purchase products from the 8T3 Essentials line, please visit our online shop: www.8T3.com

For more information, visit www.mallia.com and follow us on LinkedIn, Instagram, and Facebook.
 

¹ Royzman, D., Peckert-Maier, K., Stich, L., König, C., Wild, A. B., Tauchi, M., … & Steinkasserer, A. (2022). Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages. Frontiers in Immunology, 13, 1012647. DOI: 10.3389/fimmu.2022.1012647

² Bock, F., Rössner, S., Onderka, J., Lechmann, M., Pallotta, M. T., Fallarino, F., … & Zinser, E. (2013). Topical application of soluble CD83 induces IDO-mediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival. The Journal of Immunology, 191(4), 1965-1975. DOI: 10.4049/jimmunol.1201531

³ Ali, N., Zirak, B., Rodriguez, R. S., Pauli, M. L., Truong, H. A., Lai, K., … & Rosenblum, M. D. (2017). Regulatory T cells in skin facilitate epithelial stem cell differentiation. Cell, 169(6), 1119-1129. DOI: 10.1016/j.cell.2017.05.002

⁴ Feinstein, R. P. (2022). Androgenetic alopecia.: https://emedicine.medscape.com/article/1070167-overview

⁵ Mostaghimi, A., Gandhi, K., Done, N., Ray, M., Gao, W., Carley, C., … & Sikirica, V. (2022). All-cause health care resource utilization and costs among adults with alopecia areata: A retrospective claims database study in the United States. Journal of Managed Care & Specialty Pharmacy, 28(4), 426-434: DOI: 10.18553/jmcp.2022.28.4.426

⁶ Lechmann, M., Krooshoop, D. J., Dudziak, D., Kremmer, E., Kuhnt, C., Figdor, C. G., … & Steinkasserer, A. (2001). The extracellular domain of CD83 inhibits dendritic cell–mediated T cell stimulation and binds to a ligand on dendritic cells. The Journal of experimental medicine, 194(12), 1813-1821. DOI: 10.1084/jem.194.12.1813

Not for release, publication or distribution, directly or indirectly, in or intothe United States of America, Australia, Canada or Japan or any otherjurisdiction in which such release, publication or distribution would be unlawful. The important notes at the end of this announcement need to be observed.

• Consistent implementation of Cantourage’s European growth strategy
• Positioning as a premium partner in Poland’s medical cannabis market
• Additional products for the Polish market currently in the registration process

Berlin, 4 November 2025 – Cantourage Group SE continues to expand its activities in the European medical cannabis market and is launching the “Gelato 33” strain from Canadian cultivator LOT420 in Poland for the first time. Following the successful introduction of the strain MAC 1 at the end of 2024, Cantourage’s collaboration with Polish wholesaler PharmaVitae continues to expand.

The Polish market experienced a temporary slowdown at the end of 2024 following regulatory changes – particularly restrictions on online prescriptions. However, market observers expect demand to recover significantly over the course of 2025 and reach new record levels in 2026.

Together with PharmaVitae, Cantourage is preparing for this anticipated growth. The two partners aim to at least double sales next year – from around 500 kilograms in 2025 to over one tonne of cannabis flowers in 2026. In addition to the now available Gelato 33 and MAC 1 varieties, four other products that are already in high demand in Germany are currently undergoing the approval process for the Polish market.

“Poland is increasingly becoming one of the most exciting European markets,” says Philip Schetter, CEO of Cantourage. “Together with PharmaVitae, we are building on an extremely successful first year. The strong demand shows that our commitment to quality resonates internationally.”

Malgożata Leman-Borsuk, CEO of PharmaVitae, adds: “Our partnership with Cantourage has proven to be extraordinarily successful from the start. With Gelato 33, we are expanding our portfolio with another strain that has great potential in Poland.”

The Canadian cultivator LOT420 is also pleased to see its products becoming available in yet another country: “At LOT420 we strive to provide patients with the best quality cannabis, being able to expand our products into a new country is always a great honor. We hope that our Gelato 33 cultivar will be well received by Poland’s medical patients and become a staple within the medical cannabis community,” says Stefan Macdonald, CEO of LOT420.

In light of the ongoing discussion about potential regulatory changes in its home market Germany, Cantourage is increasingly focusing on diversifying across Europe. At the same time, the company remains confident that Germany will continue to be its most important market. The current market developments in Poland, in particular, demonstrate that demand for high-quality and safe medical cannabis products continues to grow – regardless of the distribution channel.

About Cantourage
Cantourage is a leading European producer and distributor of cannabis flowers and cannabis-based medicinal preparations and drugs. The Berlin-based company was founded in 2019 by industry pioneers Norman Ruchholtz, Dr. Florian Holzapfel and Patrick Hoffmann. With an experienced management team and its “Fast Track Access” platform, Cantourage enables producers from around the world to become part of the growing European medical cannabis market faster, easier and more cost-effectively by processing and distributing their cannabis raw materials and extracts. In this context, Cantourage ensures compliance with the highest European pharmaceutical quality standards at all times. The company offers pharmaceutical-grade products in all relevant market segments: dried flower, extracts, dronabinol and cannabidiol. Cantourage was listed on the Frankfurt Stock Exchange on 11 November 2022 – ISIN: DE000A3DSV01.

Further information: www.cantourage.com

About PharmaVitae
PharmaVitae is a privately owner Polish company founded in 2011 that specializes in the import and distribution of Rx and OTC pharmaceuticals, medical devices and cosmetics. The company supplies pharmacies, doctors, hospitals, clinics and drugstores throughout Poland and reported annual salesof PLN 80 million in 2023. PharmaVitae ensures efficient and reliable distribution with its modern, WDL-certified warehouse that meets all GDP requirements and can accommodate up to 2,000 pallets.

Further information: www.pharmavitae.com.pl

Investor Relations contact at Cantourage

Manuel Taverne
taverne@cantourage.com

This announcement does not constitute a public offer or an advertisement for a public offer to sell securities, in particular not within the meaning of Regulation (EU) 2017/1129 (Prospectus Regulation).

Abivax Announces Patient-Reported Outcomes Data from the Phase 3 ABTECT Induction Trials of Obefazimod, Demonstrating Significant Improvements in Quality of Life for Patients with Moderate-to-Severely Active Ulcerative Colitis

• Improvements across all patient reported outcomes (PROs) were observed from baseline to Week 8 in all PRO instruments utilized in the ABTECT induction trials evaluating bowel urgency, sleep interruption, fatigue, quality of life, and work productivity for both 50mg and 25mg once-daily obefazimod. 
• At week 8 in the ABTECT 1 & 2 trials, 37% of patients taking once daily 50mg obefazimod reported no bowel urgency (BU) compared to 18.1% of patients in the placebo group (18.9, p<0.0001[1]), with improvements in BU observed as early as week two
• 47.6% of patients on 50mg obefazimod reported no nocturnal bowel movements (NBM) at week 8 compared to 24.7% in the placebo group (23.1, p<0.0001¹)
• In the 50 mg group 17.1% of patients reported fatigue remission as measured with the Fatigue Numerical Rating Scale (NRS) at week 8, compared to 7.7% in the placebo group ( 9.5, p=0.0001¹)
• Detailed data across PROs, including data for both 25mg and 50mg groups, to be submitted for presentation at upcoming medical meetings

PARIS, France – November 3, 2025 – 10:05 PM CET – Abivax SA (Euronext Paris: FR0012333284 – ABVX / Nasdaq: ABVX) (“Abivax” or the “Company”), a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases, today announced patient-reported outcomes (PRO) from its Phase 3 ABTECT 8-week induction trials evaluating obefazimod in adult patients with moderate-to-severely active ulcerative colitis (UC). In addition to the trials’ clinical efficacy endpoints, PRO instruments are important in determining how patients perceived changes in their symptoms, quality of life, and activities of daily living.

“Ulcerative colitis can be a devastating condition that affects every aspect of a person’s daily life, including their ability to work, socialize, and maintain their emotional well-being,” said Marla Dubinsky, MD[2], Professor of Pediatrics and Medicine, Chief, Division of Pediatric Gastroenterology and Nutrition, Co-Director, Susan and Leonard Feinstein IBD Clinical Center, Mount Sinai Kravis Children’s Hospital, Icahn School of Medicine Mount Sinai New York. “For these patients, improvement isn’t just about controlling inflammation, it’s about regaining a sense of normalcy. That’s why measures of quality of life are so important when evaluating potential new therapies so that we also capture the outcomes that truly matter to patients, and bowel urgency is one of these key factors. The consistency of improvements across all PRO instruments utilized in this program underscores the meaningful benefit obefazimod provided to patients’ daily experience and supports the positive Phase 3 efficacy results observed at week 8. Together, these results highlight obefazimod’s potential to meaningfully advance care for patients with UC.”

PRO instruments evaluated in the ABTECT trials include:

• Bowel urgency
• Nocturnal bowel movement
• Fatigue numerical rating scale (NRS)
• Fatigue and ability to function (FACIT-F)
• Inflammatory bowel disease questionnaire (IBDQ)
• Overall quality of life (EQ-5D-5L)
• Workplace productivity (WPAI Domains)

Detailed analysis of these PROs will be submitted for presentation at an upcoming medical conference. 

Marc de Garidel, MBA, Chief Executive Officer of Abivax, commented, “The data shared today further support obefazimod’s potential as a meaningful treatment option for patients with ulcerative colitis (UC). Our development efforts, guided by the recognized need for more effective and tolerable long-term therapies, are focused on advancing treatments that can significantly improve patients’ quality of life. Taken together with the previously reported positive ABTECT 8-week induction trial results, we are one step closer to realizing this goal. We will be submitting more detailed aspects of this dataset for presentation at an upcoming medical meeting and look forward to sharing results from our 44-week maintenance trial in the second quarter of 2026.”

About Abivax

Abivax is a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases. Based in France and the United States, Abivax’s lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of moderately to severely active ulcerative colitis.

Contact:

Patrick Malloy
SVP, Investor Relations
Abivax SA
patrick.malloy@abivax.com
+1 847 987 4878

FORWARD-LOOKING STATEMENTS

This press release contains forward-looking statements, forecasts and estimates, including those relating to the Company’s business. Words such as “anticipate,” “expect,” “potential” and variations of such words and similar expressions are intended to identify forward-looking statements. These forward-looking statements include statements concerning the Company’s anticipated timing for data readouts of its ABTECT induction and maintenance clinical trials and the potential therapeutic benefit of obefazimod. Although Abivax’s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks, contingencies and uncertainties, many of which are difficult to predict and generally beyond the control of Abivax, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. A description of these risks, contingencies and uncertainties can be found in the documents filed by the Company with the French Autorité des Marchés Financiers pursuant to its legal obligations including its universal registration document (Document d’Enregistrement Universel) and in its Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission on March 24, 2025 under the caption “Risk Factors.” These risks, contingencies and uncertainties include, among other things, the uncertainties inherent in research and development, future clinical data and analysis, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug candidate, as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates, and the availability of funding sufficient for the Company’s foreseeable and unforeseeable operating expenses and capital expenditure requirements. Special consideration should be given to the potential hurdles of clinical and pharmaceutical development, including further assessment by the Company and regulatory agencies and IRBs/ethics committees following the assessment of preclinical, pharmacokinetic, carcinogenicity, toxicity, CMC and clinical data. Furthermore, these forward-looking statements, forecasts and estimates are made only as of the date of this press release. Readers are cautioned not to place undue reliance on these forward-looking statements. Abivax disclaims any obligation to update these forward-looking statements, forecasts or estimates to reflect any subsequent changes that the Company becomes aware of, except as required by law. Information about pharmaceutical products (including products currently in development) that is included in this press release is not intended to constitute an advertisement. This press release is for information purposes only, and the information contained herein does not constitute either an offer to sell or the solicitation of an offer to purchase or subscribe for securities of the Company in any jurisdiction. Similarly, it does not give and should not be treated as giving investment advice. It has no connection with the investment objectives, financial situation or specific needs of any recipient. It should not be regarded by recipients as a substitute for exercise of their own judgment. All opinions expressed herein are subject to change without notice. The distribution of this document may be restricted by law in certain jurisdictions. Persons into whose possession this document comes are required to inform themselves about and to observe any such restrictions.  

[1] ABTECT-1&2 pooled analysis; all p-values are nominal.  Endpoints are secondary and not alpha controlled.

[2] Marla Dubinsky, MD is a paid consultant for Abivax.

Press release 

Thomas Meier becomes new CEO of Medios AG

Berlin, November 3, 2025 – The Supervisory Board of Medios AG has appointed Thomas Meier as a member of the Executive Board with effect from February 1, 2026, and designated him the new Chief Executive Officer (CEO) of the Company. He succeeds Matthias Gaertner, who will remain in office until December 31, 2025.

Thomas Meier has been CEO of the Swiss CDMO (Contract Development and Manufacturing Organization) company Bachem Holding AG, which is also listed on the stock exchange, since 2020. Prior to this, he was Chief Operations Officer on the Executive Board of Bachem and worked as Head of Manufacturing at Peninsula Laboratories in San Carlos, California, USA, from 2001 to 2004. Thomas Meier will play a key role in driving the further growth of the Medios Group.

Dr. Yann Samson, Chairman of the Supervisory Board of Medios AG: “With Thomas Meier, we are gaining an internationally experienced leader with a strong track record of capital-efficient, profitable growth. We warmly welcome him and are convinced that his entrepreneurial spirit, expertise and leadership will contribute significantly to achieving our ambitious goals and sustainably increasing value for shareholders, partners, and customers. At the same time, on behalf of the entire Supervisory Board, I would like to express my sincere thanks to Matthias Gaertner for his outstanding work and great commitment over the past ten years. He has had a decisive influence on the growth and success of Medios.”

Thomas Meier: “I am very much looking forward to the task of leading Medios into its next phase of development. Together with my colleagues on the Executive Board and the entire Medios team, I will continue to consistently develop the successful strategy and sustainably expand Medios’ position in the European Specialty Pharma market.”
 

Important dates for Medios in the 2025 financial year

——————-

About Medios AG

Medios is a leading provider of Specialty Pharma in Europe. With locations in Germany, the Netherlands, Belgium and Spain, the Company supports key partners in the supply chain with innovative solutions and intelligent services. Medios has focused on pioneering individualized medicine to make the most innovative therapies available to everyone together with pharmacies, specialist practices and pharmaceutical companies.

Medios AG is Germany’s first listed specialty pharmaceutical Company. The shares (ISIN: DE000A1MMCC8) are listed on the regulated market of the Frankfurt Stock Exchange (Prime Standard) and are included in the SDAX selection index.

www.medios.group 

More information on the topic of individualized medicine: https://app.medios.group/en/individualizedmedicine
 

Contact

Claudia Nickolaus

Head of Investor & Public Relations, ESG Communications

Medios AG

Heidestraße 9 | 10557 Berlin

T +49 30 232 566 800

ir@medios.group

www.medios.group

PRESS RELEASE

Heidelberg Pharma to Present New Clinical Data of Lead ADC Candidate HDP-101 at the World ADC Congress 2025 and to Host Webinar

• Objective responses and promising anti-tumor activity observed in several patients across multiple cohorts in the ongoing Phase I/IIa clinical trial
• Data reinforces the therapeutic potential and safety profile of HDP-101 in relapsed or refractory multiple myeloma.
• R&D Webinar to be hosted on 11 November 2025 at 05:00 pm CET (08:00 am PST)

Ladenburg, Germany, 3 November 2025 – Heidelberg Pharma AG (FSE: HPHA), a clinical-stage developer of innovative Antibody Drug Conjugates (ADCs), today announced the presentation of new clinical data from its ongoing Phase I/IIa clinical study evaluating its lead Amanitin-based ADC candidate, HDP-101 (INN: pamlectabart tismanitin), at the 16^th Annual World ADC Congress, taking place in San Diego, California, from 3 to 6 November 2025.

HDP-101 (INN: pamlectabart tismanitin) is an anti-BCMA antibody-drug conjugate being investigated for the treatment of relapsed or refractory multiple myeloma, a bone marrow cancer with a high unmet medical need. Phase I of the ongoing study is a dose-escalation trial designed to determine the optimal and safe dose level of HDP-101 in preparation for subsequent Phase II clinical evaluation.

Professor Andreas Pahl, Chief Executive Officer of Heidelberg Pharma, will present an update from patient cohort 8 including efficacy data of the open-label, multicenter Phase I/IIa study evaluating HDP-101 in patients with relapsed or refractory multiple myeloma.

Details of the presentation at 16^th Annual World ADC Congress:

Presentation title: From Bench to Breakthrough: The Evolution of Amanitin ADCs – Insights from HDP-101 Phase I/II & the Future of Payload Differentiation

R&D Webinar to take place with Key Opinion Leader

Following the World ADC Congress, Heidelberg Pharma will host an R&D webinar on 11 November 2025 at 05:00 pm CET (11:00 am EST; 08:00 am PST), for investors, analysts, and media.

The R&D webinar will feature presentations by the Heidelberg Pharma management team, alongside Key Opinion Leader (KOL) Professor Marc-Steffen Raab, Head of the Myeloma Center at the University Hospital Heidelberg and clinical investigator of the study.

Webinar participants will have the opportunity to submit questions in advance of the webinar or ask questions live during the event.

For further information on the R&D webinar, or to register your attendance, please use the link below:

https://us06web.zoom.us/webinar/register/WN_AG_mESPaT-aSsm8_O2DllA

A recording of the R&D webinar will be accessible via the press & investor section of the Company website after the event.

About Heidelberg Pharma

Heidelberg Pharma is a biopharmaceutical company working on a new treatment approach in oncology and developing novel drugs based on its ADC technologies for the targeted and highly effective treatment of cancer. ADCs are antibody-drug conjugates that combine the specificity of antibodies with the efficacy of toxins to fight cancer. Selected antibodies are loaded with cytotoxic compounds, the so-called payloads, that are transported into diseased cells. Inside the cells, the toxins then unleash their effect and kill the diseased cells.

Heidelberg Pharma is the first company to use the compound Amanitin from the green death cap mushroom in cancer therapy. The biological mechanism of action of the toxin represents a new therapeutic modality and is used as a compound in the Amanitin-based ADC technology, the so-called ATAC technology.

The lead candidate HDP-101 is a BCMA ATAC in clinical development for multiple myeloma. A second ATAC candidate, HDP-102, has recently started clinical development in Non-Hodgkin Lymphoma and is currently on a temporary hold. HDP-103 against metastatic castration-resistant prostate cancer and HDP-104 targeting gastrointestinal tumors such as colorectal cancer have completed preclinical development. Heidelberg Pharma is open for partnering.

The company is based in Ladenburg, Germany, and is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol HPHA. More information is available at www.heidelberg-pharma.com

ATAC^® is a registered trademark of Heidelberg Pharma Research GmbH.

This communication contains certain forward-looking statements relating to the Company’s business, which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “will”, “should”, “future”, “potential” or similar expressions or by a general discussion of the Company’s strategy, plans or intentions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results of operations, financial condition, performance, achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors and partners are cautioned not to place undue reliance on such forward-looking statements. We disclaim any obligation to update any such forward-looking statements to reflect future events or developments.

Ad hoc announcement pursuant to Art. 53 LR

Fribourg, 3 November 2025

AEVIS VICTORIA SA (AEVS.SW) – Continued revenue growth in the third quarter of 2025

Consolidated growth of 18.2%, driven by the Healthcare and Hospitality divisions. Adjusted organic growth of 2.6%.

AEVIS VICTORIA SA (AEVIS) achieved consolidated gross revenue of CHF 899.2 million in the first nine months of 2025, compared to CHF 761.0 million in the same period of 2024, representing total growth of 18.2%. Net revenue amounted to CHF 789.9 million (3Q2024: CHF 668.6 million), up 18.1%, including adjusted organic growth of 1.5%.

Healthcare: sustained growth and successful integration of new entities
With its 21 hospitals and its outpatient centers, Swiss Medical Network generated gross revenue of CHF 722.6 million (3Q2024: CHF 594.9 million), up 21.5%. Adjusted organic growth reached 3.3%, supported by the expansion of the outpatient network and the full integration of Spital Zofingen, CentroMedico in Ticino, and several medical practices in German-speaking Switzerland. Swiss Medical Network is continuing its expansion in integrated care, with the extension of the integrated care model to a third region, Aare Netz – the first in German-speaking Switzerland – on 1 January 2026.

Viva Health: Attractive premiums in all cantons within the integrated care regions
VIVA Health, the alternative basic insurance product developed in collaboration with insurer Visana, is entering its third year with the lowest premiums on the market in most categories and cantons. Viva is available in the Jura Arc, Ticino, and Zofingen/Aarau regions.

Hospitality: positive momentum maintained
MRH Switzerland AG, the group’s hotel division managed by Michel Reybier Hospitality, generated gross revenue of CHF 157.4 million (3Q2024: CHF 151.6 million), up 3.8%. Organic growth was supported by excellent performance across all establishments. The winter season, starting on 12 December 2025, looks promising, as Switzerland continues to strengthen its appeal as a travel destination. The hotel portfolio has remained unchanged at eleven properties.

Real Estate: strong contribution driven by apartment sales in Zermatt
The Real Estate division, represented by Swiss Hotel Properties SA, recorded revenue of CHF 36.1 million (3Q2024: CHF 24.0 million), up 50.5%. This increase was mainly due to the sale of apartments in Zermatt, around one-third of which have already been sold. The remaining units will be marketed by the end of the winter season (1Q2026), further supporting the division’s revenue in the next quarter.

Strategic options under review
AEVIS VICTORIA is currently exploring various strategic options for its subsidiaries, particularly Swiss Medical Network and Infracore, to support their long-term development. Swiss Medical Network aims to cover all regions where it operates with its integrated care offering and with Viva, the alternative basic insurance product developed with Visana. In this context, AEVIS plans to welcome new strategic shareholders and intends to reduce its participation in Swiss Medical Network in order to strengthen the independence of the Swiss integrated care group. In parallel, Infracore is exploring various opportunities to open up its capital base, potentially including a listing, to meet the growing demand for sale-and-leaseback solutions in the public and private hospital market in Switzerland.

For further information:
AEVIS VICTORIA SA Media and Investor Relations: c/o Dynamics Group, Zurich
Philippe R. Blangey, prb@dynamicsgroup.ch, +41 (0) 43 268 32 35 or +41 (0) 79 785 46 32
Séverine Van der Schueren, svanderschueren@aevis.com, +41 (0) 79 635 04 10

AEVIS VICTORIA SA – Investing for a better life
AEVIS VICTORIA SA invests in healthcare, hospitality & lifestyle and infrastructure. AEVIS′s main shareholdings are Swiss Medical Network Holding SA (76.3%, directly and indirectly), the only Swiss private network of hospitals present in the country’s three main language regions, MRH Switzerland AG, a luxury hotel group managing eleven hotels in Switzerland and abroad, Infracore SA (30%, directly and indirectly), a real estate company dedicated to healthcare-related infrastructure, Swiss Hotel Properties SA, a hospitality real estate division, and NESCENS SA, a brand dedicated to better aging. AEVIS is listed on the Swiss Reporting Standard of the SIX Swiss Exchange (AEVS.SW).
www.aevis.com.

STRATEC REPORTS SUPPLY CHAIN-RELATED PRODUCTION DELAYS, ADJUSTMENT TO 2025 SALES GUIDANCE AND PRELIMINARY RESULTS FOR 9M/2025

Birkenfeld, October 30, 2025

STRATEC SE, Birkenfeld, Germany (Frankfurt: SBS; Prime Standard, SDAX), expects to witness temporary interruptions to the supply of input materials for some of its system lines in the fourth quarter of 2025. In particular, in connection with trade policy tensions a supply chain interruption has arisen in recent weeks for a specific type of magnet with impurities relating to export-restricted rare earths (0.1% share of affected production batch). Against this backdrop, delivery backlogs already arose for system deliveries in the third quarter of 2025. Following close communication with its suppliers, STRATEC now no longer expects to receive sufficient quantities of input materials to make up for these delivery backlogs or for the production volumes originally planned for the fourth quarter of 2025. Furthermore, global tariff conflicts are leading to greater fluctuations in customers’ order behavior and to associated inventory optimization measures. These particularly affect the Service Parts and Consumables business.

In view of these factors, the Board of Management has decided to adjust its sales guidance for the 2025 financial year. STRATEC now expects its consolidated sales at constant currency to approximately match the previous year’s figure (previously: “consolidated sales at constant currency to show growth in a low to medium single-digit percentage range”). Despite the lower sales base hereby forecast and negative currency items, STRATEC nevertheless expects to achieve the lower end of the forecast corridor of around 10.0% to 12.0% for its adjusted EBIT margin. This expected intra-year rise in profitability in the fourth quarter of 2025 is attributable to benefits of scale, efficiency measures, and higher earnings contributions from the realization of high-margin development sales.

Based on preliminary figures and despite the delivery backlogs that have already arisen, in the first nine months of 2025 STRATEC was able to increase its consolidated sales at constant currency year-on-year by 2.5% to € 175.6 million (9M/2024: € 173.0 million). The adjusted EBIT margin for the first nine months is expected to amount to 7.3% (9M/2024: 8.8%).

STRATEC will publish its definitive results and its Quarterly Statement for the first nine months of 2025 as planned on November 7, 2025.

FURTHER INFORMATION IS AVAILABLE FROM:
STRATEC SE
Jan Keppeler, CFA | Investor Relations, Sustainability & Corporate Communications
Tel: +49 7082 7916-6515
ir@stratec.com
www.stratec.com

Not for release, publication or distribution, directly or indirectly, in or intothe United States of America, Australia, Canada or Japan or any otherjurisdiction in which such release, publication or distribution would be unlawful. The important notes at the end of this announcement need to be observed.

• Revenue up 148% to EUR 75 million in the first nine months of 2025
• On track to become a European player – market liberalization in other European countries offers opportunities
• Outlook – Focus on further growth and geographic diversification

Berlin, 30 October 2025 – Cantourage Group SE continued its positive business development in the third quarter of 2025 and consolidated its position as one of the leading players in the European medical cannabis market, despite a challenging regulatory environment in Germany.

In the third quarter of 2025, Cantourage generated revenue of around EUR 20.1 million (comparable period 2024: EUR 13.2 million). This resulted in total group revenue of around EUR 74.9 million at the end of the third quarter (comparable period 2024: EUR 30.2 million). EBITDA of roughly EUR 3.9 million (comparable period in 2024: EUR 2.1 million) at the end of Q3 2025 underscores the strong operating performance and high scalability of the business model.

Robust development in Germany

In Germany, Cantourage recorded a robust development in both the cannabis flower and pharmaceutical ingredient business. Cantourage was able to further consolidate its position and successfully meet the demand for high-quality medical cannabis products.

“Germany remains a challenging market in a difficult regulatory and economic environment. Despite the current positive development, we are monitoring the broader conditions with due attention,” says Philip Schetter, CEO of Cantourage Group SE.

Growth in international markets

Cantourage is also continuing its growth trajectory outside Germany: positive momentum is continuing in the UK, while business is being expanded in a strategic approach in Poland. At the same time, Cantourage is preparing to enter other European growth markets such as Spain and Italy in order to benefit from the opening of these markets at an early stage.

Innovation and digitalization

Cantourage is continuing to develop its telemedicine offering in Germany in anticipation of regulatory changes, so that patients will continue to have the best possible and safe access to medical cannabis in the future. At the same time, the company is working on the development of new, innovative product formats that are designed to better meet the needs of patients.

Outlook

Against the backdrop of its operational performance to date in 2025, Cantourage is confident about the fourth quarter and the full year 2025. The company considers itself well positioned to achieve further growth in existing and new markets, but remains attentive to potential market changes. Note:

All figures are preliminary, unaudited, and unconsolidated.

About Cantourage
Cantourage is a leading European producer and distributor of cannabis flowers and cannabis-based medicinal preparations and drugs. The Berlin-based company was founded in 2019 by industry pioneers Norman Ruchholtz, Dr. Florian Holzapfel and Patrick Hoffmann. With an experienced management team and its “Fast Track Access” platform, Cantourage enables producers from around the world to become part of the growing European medical cannabis market faster, easier and more cost-effectively by processing and distributing their cannabis raw materials and extracts. In this context, Cantourage ensures compliance with the highest European pharmaceutical quality standards at all times. The company offers pharmaceutical-grade products in all relevant market segments: dried flower, extracts, dronabinol and cannabidiol. Cantourage was listed on the Frankfurt Stock Exchange on 11 November 2022 and is listed under – ISIN: DE000A3DSV01. 

Further information: www.cantourage.com

Investor Relations contact at Cantourage

Manuel Taverne
taverne@cantourage.com

This announcement does not constitute a public offer or an advertisement for a public offer to sell securities, in particular not within the meaning of Regulation (EU) 2017/1129 (Prospectus Regulation).