Trilink – highly modified oligos

TriLink is biotech company supplying RNA and DNA oligonucleotides for pre-clinical research and specialized in highly modified oligos, including RNA oligonucleotides and derivatives (2′ Fluoro RNA, 2′ O-Methyl RNA, etc…).

Trilink – highly modified oligos


TriLink is specialized in the manufacture of modified nucleic acid products including custom oligonucleotides, mRNA, modified nucleoside triphosphates, CleanAmp PCR Products, phosphoramidites, etc… TriLink is a leader in synthesizing high quality oligonucleotides for research, diagnostics, OEM and therapeutics, offering a wide selection of DNA and RNA (modified oligonucleotides, siRNA, microRNA, aptamers, etc…) in scales from 0.2 µmol up to multiple grams. TriLink has in stock over 150 modified compounds, including Aminoallyl, Biotin and 2′ Fluoro nucleotides. And TriLink also offers specialty modified nucleotides such as bisphosphates, a series of monophosphates, CAP and mCAP, etc… CleanAmp Hot Start PCR is a patented technology providing a specific, sensitive and flexible alternative to Hot Start DNA polymerases. TriLink has applied this expertise in modified nucleic acid chemistry to develop chemically modified dNTPs and primers that enable Hot Start PCR using standard Taq DNA polymerase. CleanAmp products are thus ideal for applications such as multiplex PCR, RT-PCR, fast PCR, digital PCR, end-point PCR, etc… Furthermore, new base modifications involved in epigenetic pathways are continually being discovered (i.e. 5-Hydroxymethyl-dC, 5-Hydroxymethyl-dU and 5-Formyl-dC were recently acknowledged as key players in the epigenetic pathway for 5-Methyl-dC). TriLink offers both DNA and RNA nucleoside triphosphates and oligonucleotide base modifications for epigenetic research.

Trilink Biotechnologies was founded in 1996 and I headquartered in San Diego (USA). TriLink also offers its CleanTag Library Preparation for Next-Generation Sequencing. CleanTag technology solves one of the most pervasive problems in library preparation for next-generation sequencing (NGS): adapter dimer formation. TriLink applied its nucleic acid expertise to develop CleanTag modified adapters to block adapter dimer formation.

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Trilink – Trilink Biotech – Trilink Biotechnologies – RNA oligonucleotides – DNA oligonucleotides

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